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| Title: | | HAMMERHEAD RIBOZYME WITH 5'-5' G-G LINKAGE: CONFORMATIONAL CHANGE EXPERIMENT | |
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| Molecular Description: | 5'-R(GpGpUpGpGpUpCpUpGpApUpGpApGpGpCp
C)-3'/Ribozyme |
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| Structural Features: | A DOUBLE HELIX, HAMMERHEAD, RNA HAMMERHEAD RIBOZYME, LOOP, HAIRPIN LOOP |
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| Nucleic Acid Sequence: |
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| Chain | A: | |
G G U G G U C U G A U G A G G C C
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| Chain | B: | |
G C C G A A A C U C G U A A G A G U C A C C A C
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| Primary Citation: | Dunham, C.M., Murray, J.B., Scott, W.G.
A helical twist-induced conformational switch activates cleavage in the hammerhead ribozyme.
J.Mol.Biol.
, 332,
pp. 327 - 336, 2003.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
31
2
1
|
|
| Cell Constants: |
| a = 66.689 | b = 66.689 | c = 140.528 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
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| Refinement: | The structure was refined using the REFMAC 5.1.24 program.
The R value is
24.196
for 6872 reflections
in the resolution range 19.80 to
3.00 Ångstroms
with Fobs > 0 sigma(Fobs).
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