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| Title: |  | GUANINE RIBOSWITCH BOUND TO HYPOXANTHINE |  |
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| Molecular Description: | 67-MER |
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| Structural Features: | SINGLE STRAND, TETRAPLEX, BASE TRIPLET, BASE INTERCALATED |
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| Nucleic Acid Sequence: |
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| Chain | A: | |
G G A C A U A U A A U C G C G U G G A U A U G G C A C G C A A G U U U C U A C C G G G C A C C G U A A A U G U C C G A C U A U G U C C A
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| Primary Citation: | Batey, R.T., Gilbert, S.D., Montange, R.K.
Structure of a natural guanine-responsive riboswitch complexed with the metabolite hypoxanthine.
Nature
, 432,
pp. 411 - 415, 2004.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
C
1
2
1
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| Cell Constants: |
| a = 132.298 | b = 35.250 | c = 42.225 | (Ångstroms) |
= 90.00 | = 90.95 | = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, HANGING DROP |
| Drop: | | cobalt hexammine, ammonium acetate, PEG
2000 H2O |
| Reservoir: | | ammonium acetate, PEG
2000 cobalt hexammine, H2O |
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| Refinement: | The structure was refined using the CNS 1.1 program.
The R value is
17.8
for 25786 reflections
in the resolution range 19.41 to
1.95 Ångstroms
with Fobs > 0.0 sigma(Fobs).
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