1 72 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 90 CGCUUCAUAU AAUCCUAAUG AUAUGGUUUG GGAGUUUCUA CCAAGAGCCU UAAACUCUUG AUUAUGAAGU GA Crystallography ? ? Angstroms 1 C O3' 3.523 -6.175 -2.086 2 G P 4.855 -6.578 -1.296 O3' 8.869 -4.186 -2.336 3 C P 9.833 -4.811 -1.208 O3' 13.490 -1.553 0.883 4 U P 14.313 -2.406 1.966 O3' 15.857 -0.257 6.270 5 U P 16.654 -1.454 6.974 O3' 16.015 -1.832 12.695 6 C P 16.597 -3.255 13.129 O3' 13.888 -5.111 17.400 7 A P 14.773 -6.431 17.604 O3' 11.884 -10.122 20.105 8 U P 12.887 -11.357 20.269 O3' 11.353 -16.188 19.782 9 A P 12.758 -16.957 19.884 O3' 13.909 -20.872 17.171 10 U P 15.137 -20.926 18.200 O3' 18.615 -17.322 15.574 11 A P 19.295 -16.247 16.555 O3' 24.380 -17.486 15.147 12 A P 24.417 -17.083 13.587 O3' 25.722 -20.937 10.251 13 U P 27.260 -21.318 10.448 O3' 28.225 -23.547 15.087 14 C P 29.213 -24.780 14.699 O3' 28.753 -29.205 17.376 15 C P 29.840 -30.278 16.880 O3' 29.066 -35.256 17.128 16 U P 30.369 -35.889 16.429 O3' 29.921 -40.428 13.849 17 A P 31.460 -40.646 13.420 O3' 32.332 -43.789 9.375 18 A P 33.902 -43.956 9.113 O3' 35.978 -43.011 4.011 19 U P 37.552 -42.855 3.801 O3' 39.484 -39.764 0.135 20 G P 41.042 -39.985 0.452 O3' 44.129 -35.973 -0.491 21 A P 45.688 -36.107 -0.198 O3' 49.125 -31.987 1.720 22 U P 50.588 -32.186 2.347 O3' 51.885 -27.301 5.556 23 A P 53.085 -26.451 4.883 O3' 52.444 -20.720 5.072 24 U P 53.118 -19.817 3.903 O3' 49.193 -22.046 -0.441 25 G P 47.510 -22.631 0.138 O3' 45.152 -26.215 1.627 26 G P 43.611 -25.809 1.733 O3' 40.206 -26.994 5.368 27 U P 38.953 -26.096 4.928 O3' 37.575 -27.167 -0.091 28 U P 35.962 -27.068 -0.200 O3' 33.500 -30.882 -3.183 29 U P 31.921 -30.575 -3.151 O3' 27.725 -34.076 -1.726 30 G P 26.311 -33.683 -1.094 O3' 23.233 -37.423 0.588 31 G P 22.042 -36.518 1.143 O3' 19.378 -38.055 5.303 32 G P 18.408 -36.804 5.644 O3' 17.086 -36.239 10.777 33 A P 16.154 -35.002 11.209 O3' 15.839 -33.054 15.779 34 G P 14.675 -31.959 15.612 O3' 14.978 -27.046 17.514 35 U P 13.397 -27.358 17.649 O3' 10.221 -22.791 16.103 36 U P 9.434 -22.125 17.325 O3' 5.374 -25.684 14.779 37 U P 6.603 -26.466 14.110 O3' 8.058 -25.255 8.795 38 C P 8.962 -26.443 8.230 O3' 9.480 -26.439 3.112 39 U P 10.908 -27.177 3.193 O3' 14.915 -24.674 0.791 40 A P 16.326 -25.367 0.966 O3' 20.854 -22.641 1.763 41 C P 21.896 -23.854 1.589 O3' 25.705 -24.169 5.353 42 C P 26.498 -25.299 4.518 O3' 29.562 -21.837 1.188 43 A P 31.155 -21.663 1.247 O3' 33.582 -17.422 -0.200 44 A P 35.150 -17.594 0.002 O3' 38.101 -13.362 1.220 45 G P 39.533 -13.932 1.631 O3' 42.225 -11.450 5.600 46 A P 43.559 -12.268 6.011 O3' 45.165 -12.094 11.130 47 G P 46.465 -13.014 11.357 O3' 46.862 -15.328 16.222 48 C P 48.349 -15.938 16.310 O3' 48.455 -20.702 18.595 49 C P 49.935 -21.306 18.635 O3' 50.626 -26.354 17.961 50 U P 52.087 -26.156 18.567 O3' 56.871 -27.975 14.940 51 U P 57.562 -29.404 15.072 O3' 55.256 -32.942 11.030 52 A P 55.284 -34.461 11.554 O3' 50.396 -36.209 14.142 53 A P 49.420 -37.118 13.265 O3' 44.028 -35.557 15.080 54 A P 42.595 -36.207 14.825 O3' 39.520 -31.210 14.710 55 C P 38.381 -31.190 13.579 O3' 37.535 -26.999 15.616 56 U P 36.273 -25.987 15.768 O3' 35.841 -21.768 18.679 57 C P 34.536 -21.020 18.145 O3' 34.205 -15.664 18.557 58 U P 32.793 -15.111 18.076 O3' 32.647 -10.270 15.815 59 U P 31.120 -9.924 15.502 O3' 29.523 -7.454 11.339 60 G P 27.933 -7.562 11.288 O3' 25.536 -7.580 6.509 61 A P 24.007 -7.787 6.930 O3' 20.239 -10.221 3.300 62 U P 18.644 -10.031 3.226 O3' 15.872 -13.678 0.899 63 U P 14.324 -13.291 1.084 O3' 10.742 -16.815 2.171 64 A P 9.453 -15.908 2.442 O3' 5.732 -17.375 5.654 65 U P 4.787 -16.100 5.455 O3' 2.031 -14.632 9.783 66 G P 1.327 -13.289 9.232 O3' 0.600 -9.688 12.891 67 A P 0.104 -8.351 12.167 O3' 0.827 -3.730 14.703 68 A P 0.409 -2.529 13.722 O3' 2.751 2.217 14.393 69 G P 1.865 3.038 13.344 O3' 4.739 6.878 10.505 70 U P 3.629 7.512 9.531 O3' 5.358 8.949 4.526 71 G P 4.147 9.325 3.545 O3' 3.373 9.323 -1.706 72 A 52 syn 53 syn 1 71 + + c 2 70 W W c 3 69 + + c 4 68 - - c 5 67 - - c 6 66 + + c 7 65 - - c 8 64 - - c 9 63 - - c 10 40 - - c 11 34 W S t 13 33 - - c 14 32 + + c 15 31 + + c 16 30 W W c 17 29 - - c 18 28 - - c 19 27 W W c 21 54 W H t 22 53 W H t 25 49 + + c 26 48 + + c 26 54 S W t 34 41 + + c 37 64 W S c 38 63 W S c 39 72 W S c 42 60 + + c 43 59 - - c 44 58 - - c 45 57 + + c 46 56 - - c 47 55 + + c 49 53 S W c 62 72 - - c 22 25 ! ! ! 23 52 ! ! ! 25 53 ! ! ! 35 39 ! ! ! 9 35 ! ! ! 11 12 ! ! ! 12 41 ! ! ! 21 25 ! ! ! 1 71 9 13 33 7 42 60 6 25 49 2 21 54 3 SG1 10 12 SG2 20 20 SG3 24 24 SG4 34 41 SG5 50 51 SG6 61 62 SG7 72 72 1 156.478 13.040 2 156.478 34.773 3 156.478 56.506 4 156.478 78.239 5 156.478 99.972 6 156.478 121.705 7 156.478 143.438 8 156.478 165.171 9 156.478 186.904 10 169.518 186.904 11 182.557 186.904 12 195.597 186.904 13 156.478 230.370 14 156.478 252.103 15 156.478 273.836 16 156.478 295.569 17 156.478 317.302 18 156.478 339.035 19 156.478 360.768 20 156.478 373.808 21 225.028 538.760 22 220.345 517.538 23 215.662 496.315 24 206.295 453.870 25 196.929 411.426 26 192.245 390.203 27 104.318 360.768 28 104.318 339.035 29 104.318 317.302 30 104.318 295.569 31 104.318 273.836 32 104.318 252.103 33 104.318 230.370 34 91.279 230.370 35 78.239 230.370 36 65.199 230.370 37 52.159 230.370 38 39.119 230.370 39 26.080 230.370 40 13.040 230.370 41 0.000 230.370 42 108.529 252.886 43 113.212 274.109 44 117.895 295.331 45 122.578 316.553 46 127.262 337.776 47 131.945 358.998 48 141.312 401.443 49 145.995 422.666 50 150.678 443.888 51 160.045 486.333 52 164.728 507.555 53 169.411 528.778 54 174.094 550.000 55 182.879 347.758 56 178.195 326.536 57 173.512 305.314 58 168.829 284.091 59 164.146 262.869 60 159.462 241.646 61 78.239 186.904 62 91.279 186.904 63 104.318 186.904 64 104.318 165.171 65 104.318 143.438 66 104.318 121.705 67 104.318 99.972 68 104.318 78.239 69 104.318 56.506 70 104.318 34.773 71 104.318 13.040 72 104.318 0.000