1 77 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 CGCGGGGuGG AGCAGCCUGG uAGCUCGUCG GGcUCAUAAC CCGAAGAUCG UCGGuPCAAA UCCGGCCCCC GCAACCA 8 4SU 21 H2U 33 OMC 55 5MU 56 PSU LOOP1 55 61 LOOP2 14 22 LOOP3 34 38 Crystallography ? ? Angstroms 1 C P 7.992 35.655 32.515 O3' 5.399 31.575 31.123 2 G P 4.532 32.814 30.596 O3' 2.176 31.957 35.697 3 C P 1.432 30.609 36.122 O3' -3.159 29.887 39.066 4 G P -3.702 28.408 38.858 O3' -9.153 27.285 38.098 5 G P -9.706 25.830 37.753 O3' -14.349 25.392 35.864 6 G P -14.445 23.837 35.522 O3' -18.043 22.323 31.808 7 G P -17.902 20.766 31.499 O3' -19.466 19.558 26.095 8 u O3' -24.115 14.914 27.095 P -20.966 19.031 26.231 9 G P -24.716 15.773 25.892 O3' -28.665 13.841 22.367 10 G P -28.544 14.699 21.026 O3' -29.372 19.659 20.957 11 A P -28.512 20.355 22.110 O3' -28.963 24.500 24.740 12 G P -27.520 24.261 25.357 O3' -27.107 25.726 30.495 13 C P -25.696 25.487 31.206 O3' -24.234 22.841 35.778 14 A P -23.091 22.158 36.662 O3' -22.049 18.221 40.056 15 G P -20.577 17.714 40.328 O3' -19.337 12.743 41.378 16 C P -17.953 13.306 41.909 O3' -12.902 11.192 39.920 17 C P -12.186 10.271 40.992 O3' -8.283 12.225 43.645 18 U P -7.563 11.077 44.484 O3' -11.426 6.764 43.808 19 G P -11.157 5.498 42.849 O3' -15.619 4.639 39.273 20 G P -17.118 4.427 39.751 O3' -20.544 0.393 39.101 21 u P -21.226 0.706 37.696 O3' -23.268 1.158 33.521 22 A P -23.886 1.991 32.296 O3' -27.123 6.164 34.516 23 G P -28.669 5.839 34.867 O3' -31.788 10.021 36.866 24 C P -33.109 10.856 36.551 O3' -34.140 15.253 38.498 25 U P -35.549 15.283 37.795 O3' -37.733 19.846 36.368 26 C P -39.002 19.373 35.517 O3' -40.238 21.523 30.374 27 G P -41.535 20.748 29.869 O3' -41.562 20.150 24.729 28 U P -42.907 19.289 24.770 O3' -43.784 15.743 21.250 29 C P -45.243 15.210 21.662 O3' -46.555 10.509 20.404 30 G P -48.083 10.697 20.827 O3' -50.595 6.481 22.612 31 G P -51.966 7.200 23.000 O3' -54.304 5.870 27.866 32 G P -55.414 6.979 28.212 O3' -56.959 6.830 32.876 33 c O3' -58.993 10.537 36.992 P -58.241 7.783 32.997 34 U P -60.435 11.172 36.766 O3' -62.000 16.520 36.443 35 C P -63.503 16.024 36.263 O3' -63.474 16.675 31.312 36 A P -62.050 15.954 31.225 O3' -58.316 18.858 28.462 37 U P -57.212 17.722 28.377 O3' -52.685 20.184 28.355 38 A P -52.156 18.782 27.799 O3' -48.460 19.760 31.263 39 A P -47.627 21.127 31.457 O3' -47.436 20.204 37.085 40 C P -46.232 19.147 37.039 O3' -47.045 15.064 39.967 41 C P -45.769 14.203 39.532 O3' -46.287 8.967 39.392 42 C P -44.838 8.499 38.899 O3' -44.400 4.014 36.375 43 G P -42.839 4.106 36.006 O3' -41.461 2.206 31.190 44 A P -39.912 2.617 31.125 O3' -38.195 2.902 25.947 45 A P -36.644 3.217 25.807 O3' -34.907 5.332 21.243 46 G P -33.377 4.932 21.412 O3' -29.955 9.013 20.628 47 A P -28.615 8.209 20.918 O3' -23.824 9.481 21.780 48 U P -23.362 7.983 21.413 O3' -19.842 7.739 24.115 49 C P -18.619 8.750 24.402 O3' -18.037 13.947 26.709 50 G P -16.698 14.762 26.410 O3' -16.231 14.013 21.659 51 U P -15.485 12.629 21.371 O3' -11.860 11.321 18.260 52 C P -11.537 9.789 18.579 O3' -6.955 7.710 17.867 53 G P -7.067 6.207 18.406 O3' -3.147 4.236 22.307 54 G P -3.528 2.876 23.043 O3' -1.020 1.995 27.594 55 u O3' -1.709 -0.587 32.967 P -1.706 0.597 27.974 56 P O3' -5.929 -4.354 35.251 P -2.096 -2.042 32.417 57 C P -5.835 -5.721 34.420 O3' -10.096 -5.406 31.496 58 A P -9.730 -3.939 30.990 O3' -13.665 -0.805 31.170 59 A P -13.045 0.537 30.524 O3' -15.160 5.207 31.607 60 A P -16.250 5.670 30.555 O3' -13.978 9.847 30.993 61 U P -12.665 9.479 31.824 O3' -11.685 11.402 37.353 62 C P -10.520 12.492 37.257 O3' -5.724 11.743 37.262 63 C P -5.069 12.782 36.228 O3' -0.735 12.826 33.767 64 G P -0.899 14.218 33.003 O3' 1.419 14.785 28.374 65 G P 1.108 16.333 28.149 O3' 0.797 17.815 23.275 66 C P 0.188 19.288 23.137 O3' -3.361 20.778 19.077 67 C P -3.950 22.234 19.369 O3' -8.483 23.667 17.529 68 C P -8.562 25.180 18.044 O3' -13.147 27.271 19.016 69 C P -12.832 28.745 19.559 O3' -15.954 31.093 22.672 70 C P -15.161 32.441 23.004 O3' -16.076 34.912 27.783 71 G P -15.189 36.242 27.753 O3' -14.440 37.860 32.555 72 C P -13.622 39.225 32.532 O3' -9.523 40.439 36.238 73 A P -8.926 41.825 35.731 O3' -4.297 42.395 37.873 74 A P -3.951 43.916 37.520 O3' 1.232 44.662 36.179 75 C P 1.402 46.077 35.444 O3' 4.825 46.679 31.300 76 C P 4.772 48.242 30.936 O3' 5.654 49.409 25.828 77 A P 5.870 50.986 26.053 O3' 4.096 51.271 30.915 17 syn 20 syn 21 syn 38 syn 59 syn 77 syn 2 72 + + c 3 71 + + c 4 70 + + c 5 69 + + c 6 68 + + c 7 67 + + c 8 14 W H t 10 26 + + c 11 25 - - c 12 24 + + c 13 23 + + c 15 49 W W t 19 56 W S t 20 57 + + c 23 47 H W t 27 45 W W c 28 44 - - c 29 43 + + c 30 38 H W t 30 42 + + c 31 41 + + c 32 40 + + c 33 39 W W c 50 66 + + c 51 65 W W c 52 64 + + c 53 63 + + c 54 62 + + c 55 59 W H t 10 46 ! ! ! 8 22 ! ! ! 17 61 ! ! ! 18 19 ! ! ! 34 36 ! ! ! 34 37 ! ! ! 48 49 ! ! ! 56 58 ! ! ! 61 62 ! ! ! 2 72 6 50 66 5 10 26 4 27 45 7 SG1 1 1 SG2 8 9 SG3 14 22 SG4 34 38 SG5 46 49 SG6 55 61 SG7 73 77 1 55.719 55.719 2 55.719 69.649 3 55.719 92.866 4 55.719 116.082 5 55.719 139.298 6 55.719 162.515 7 55.719 185.731 8 41.789 185.731 9 27.860 185.731 10 308.338 322.749 11 285.122 322.566 12 261.906 322.383 13 238.691 322.200 14 220.581 336.695 15 197.735 340.714 16 175.766 333.271 17 160.068 316.194 18 154.497 293.676 19 160.422 271.249 20 176.387 254.422 21 198.471 247.326 22 221.250 251.704 23 239.130 266.482 24 262.345 266.665 25 285.561 266.848 26 308.777 267.031 27 355.208 267.397 28 378.424 267.580 29 401.639 267.763 30 424.855 267.946 31 448.071 268.129 32 471.286 268.312 33 494.502 268.494 34 518.739 261.876 35 541.122 273.289 36 550.000 296.792 37 540.753 320.153 38 518.193 331.212 39 494.063 324.212 40 470.847 324.029 41 447.632 323.846 42 424.416 323.663 43 401.200 323.480 44 377.985 323.297 45 354.769 323.115 46 0.000 232.164 47 13.930 232.164 48 27.860 232.164 49 41.789 232.164 50 55.719 232.164 51 55.719 255.380 52 55.719 278.597 53 55.719 301.813 54 55.719 325.029 55 44.109 345.678 56 46.072 369.285 57 60.932 387.733 58 83.579 394.678 59 106.226 387.733 60 121.086 369.285 61 123.048 345.678 62 111.439 325.029 63 111.439 301.813 64 111.439 278.597 65 111.439 255.380 66 111.439 232.164 67 111.439 185.731 68 111.439 162.515 69 111.439 139.298 70 111.439 116.082 71 111.439 92.866 72 111.439 69.649 73 111.439 55.719 74 111.439 41.789 75 111.439 27.860 76 111.439 13.930 77 111.439 0.000