1 77 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 CGCGGGGuGG AGCAGCCUGG uAGCUCGUCG GGcUCAUAAC CCGAAGAUCG UCGGuPCAAA UCCGGCCCCC GCAACCA 8 4SU 21 H2U 33 OMC 55 5MU 56 PSU LOOP1 55 61 LOOP2 14 22 LOOP3 34 38 Crystallography ? ? Angstroms 1 C P -5.706 -49.697 -48.407 O3' -3.307 -45.733 -47.228 2 G P -4.816 -45.570 -46.721 O3' -5.234 -42.942 -51.825 3 C P -4.470 -41.637 -52.345 O3' -6.288 -37.192 -55.147 4 G P -5.200 -36.028 -55.090 O3' -6.777 -30.748 -54.174 5 G P -5.790 -29.549 -53.775 O3' -8.028 -25.238 -52.055 6 G P -6.629 -24.499 -51.875 O3' -6.889 -20.591 -48.054 7 G P -5.532 -19.792 -47.717 O3' -5.779 -17.808 -42.284 8 u O3' -3.837 -11.489 -43.256 P -5.930 -16.233 -42.460 9 G P -4.799 -11.342 -41.989 O3' -5.010 -6.947 -38.538 10 G P -5.676 -7.538 -37.219 O3' -10.360 -9.361 -37.107 11 A P -10.497 -10.537 -38.193 O3' -14.471 -12.076 -40.859 12 G P -13.591 -13.274 -41.413 O3' -14.415 -14.317 -46.616 13 C P -13.458 -15.421 -47.218 O3' -10.659 -15.457 -51.818 14 A P -9.533 -15.928 -52.840 O3' -5.651 -14.941 -56.385 15 G P -4.400 -15.913 -56.498 O3' 0.484 -14.517 -57.491 16 C P 0.597 -15.953 -58.131 O3' 5.181 -19.246 -56.062 17 C P 6.172 -19.666 -57.220 O3' 6.606 -23.830 -59.735 18 U P 7.926 -23.943 -60.617 O3' 9.524 -18.422 -59.838 19 G P 10.958 -18.210 -59.103 O3' 9.208 -13.825 -55.518 20 G P 8.839 -12.336 -55.982 O3' 10.677 -7.378 -55.054 21 u P 9.914 -6.829 -53.774 O3' 8.360 -5.467 -49.750 22 A P 7.451 -5.488 -48.424 O3' 1.976 -4.457 -50.474 23 G P 1.825 -2.952 -51.031 O3' -3.362 -2.303 -53.098 24 C P -4.667 -1.571 -52.538 O3' -9.184 -2.747 -54.542 25 U P -10.015 -1.616 -53.791 O3' -14.872 -2.228 -52.396 26 C P -15.038 -0.895 -51.535 O3' -17.519 -0.975 -46.456 27 G P -17.535 0.574 -46.108 O3' -16.928 1.161 -40.837 28 U P -16.921 2.758 -40.823 O3' -13.961 5.171 -37.280 29 C P -14.310 6.687 -37.656 O3' -10.814 10.260 -36.574 30 G P -11.864 11.393 -36.966 O3' -9.573 15.753 -39.076 31 G P -10.904 16.593 -39.345 O3' -10.670 19.297 -44.124 32 G P -12.170 19.817 -44.345 O3' -12.928 21.049 -49.184 33 c O3' -17.317 20.775 -53.293 P -14.386 21.716 -49.245 34 U P -18.603 21.714 -53.195 O3' -24.107 20.678 -52.652 35 C P -24.422 22.216 -52.391 O3' -24.855 21.722 -47.373 36 A P -23.488 20.899 -47.317 O3' -24.197 16.203 -44.499 37 U P -22.679 15.766 -44.363 O3' -22.545 10.547 -44.621 38 A P -21.043 10.676 -44.078 O3' -19.984 6.962 -47.598 39 A P -20.912 5.657 -47.767 O3' -19.823 5.943 -53.333 40 C P -18.304 5.478 -53.254 O3' -15.189 8.316 -56.244 41 C P -13.806 7.581 -55.907 O3' -9.491 10.687 -55.635 42 C P -8.330 9.686 -55.158 O3' -4.215 11.720 -52.402 43 G P -3.435 10.330 -52.201 O3' -1.317 9.723 -47.115 44 A P -0.970 8.170 -47.340 O3' -0.339 6.597 -42.151 45 A P 0.101 5.069 -42.189 O3' -0.704 2.863 -37.627 46 G P 0.267 1.616 -37.844 O3' -1.592 -3.455 -36.846 47 A P -0.194 -4.204 -37.054 O3' 0.104 -9.638 -37.898 48 U P 1.401 -10.162 -37.086 O3' 4.361 -11.613 -40.093 49 C P 4.420 -13.197 -40.386 O3' 0.334 -16.239 -42.864 50 G P 0.284 -17.805 -42.557 O3' 1.023 -17.932 -37.484 51 U P 2.610 -17.748 -37.452 O3' 5.617 -20.350 -34.277 52 C P 7.060 -19.758 -34.611 O3' 11.309 -22.787 -33.970 53 G P 12.496 -21.914 -34.581 O3' 15.977 -24.380 -38.405 54 G P 16.924 -23.380 -39.216 O3' 18.973 -25.107 -43.930 55 u O3' 21.075 -23.186 -49.292 P 19.888 -23.803 -44.074 56 P O3' 22.142 -17.632 -51.420 P 22.095 -22.135 -48.679 57 C P 23.413 -17.241 -50.525 O3' 21.025 -13.677 -47.680 58 A P 19.842 -14.567 -47.078 O3' 15.100 -12.697 -47.367 59 A P 14.408 -13.956 -46.647 O3' 9.172 -14.773 -47.589 60 A P 8.281 -13.817 -46.694 O3' 5.679 -17.820 -47.072 61 U P 6.665 -18.726 -47.954 O3' 5.475 -20.443 -53.519 62 C P 5.309 -22.022 -53.356 O3' 8.357 -26.042 -53.587 63 C P 7.654 -26.987 -52.504 O3' 9.737 -30.806 -50.101 64 G P 8.544 -31.371 -49.189 O3' 9.298 -33.650 -44.654 65 G P 7.824 -34.127 -44.271 O3' 6.245 -34.493 -39.451 66 C P 4.675 -34.709 -39.182 O3' 1.619 -32.644 -35.254 67 C P 0.038 -32.759 -35.531 O3' -3.363 -29.485 -33.626 68 C P -4.715 -30.152 -34.145 O3' -9.005 -27.347 -35.131 69 C P -10.142 -28.321 -35.727 O3' -13.604 -26.747 -38.920 70 C P -14.379 -28.122 -39.168 O3' -17.019 -28.512 -43.773 71 G P -17.586 -30.005 -43.839 O3' -18.708 -31.434 -48.622 72 C P -19.448 -32.849 -48.696 O3' -18.430 -36.937 -52.479 73 A P -19.341 -38.151 -52.032 O3' -17.654 -42.439 -54.135 74 A P -18.796 -43.462 -53.683 O3' -16.790 -48.486 -52.454 75 C P -17.963 -49.242 -51.662 O3' -16.849 -52.551 -47.694 76 C P -18.203 -53.286 -47.245 O3' -18.661 -54.421 -41.931 77 A P -19.927 -55.401 -42.004 O3' -21.096 -54.565 -46.842 17 syn 20 syn 21 syn 22 syn 38 syn 59 syn 77 syn 2 72 + + c 3 71 + + c 4 70 + + c 5 69 + + c 6 68 + + c 7 67 + + c 8 14 W H t 10 26 + + c 11 25 - - c 12 24 + + c 13 23 + + c 15 49 W W t 19 56 W S t 20 57 + + c 23 47 H W t 27 45 W W c 28 44 - - c 29 43 + + c 30 38 H W t 30 42 + + c 31 41 + + c 32 40 + + c 33 39 W W c 50 66 + + c 51 65 W W c 52 64 + + c 53 63 + + c 54 62 + + c 55 59 W H t 10 46 ! ! ! 8 22 ! ! ! 17 61 ! ! ! 18 19 ! ! ! 34 36 ! ! ! 34 37 ! ! ! 48 49 ! ! ! 56 58 ! ! ! 2 72 6 50 66 5 10 26 4 27 45 7 SG1 1 1 SG2 8 9 SG3 14 22 SG4 34 38 SG5 46 49 SG6 55 61 SG7 73 77 1 494.438 55.562 2 494.438 69.453 3 494.438 92.604 4 494.438 115.755 5 494.438 138.906 6 494.438 162.057 7 494.438 185.208 8 508.328 185.208 9 522.219 185.208 10 240.662 267.086 11 263.813 266.998 12 286.964 266.910 13 310.115 266.822 14 328.004 252.158 15 350.736 247.884 16 372.729 255.050 17 388.581 271.895 18 394.398 294.282 19 388.751 316.713 20 373.028 333.679 21 351.090 341.011 22 328.326 336.911 23 310.326 322.383 24 287.175 322.472 25 264.025 322.560 26 240.874 322.648 27 194.572 322.824 28 171.421 322.912 29 148.271 323.000 30 125.120 323.088 31 101.969 323.176 32 78.818 323.264 33 55.668 323.352 34 31.578 330.234 35 9.126 319.115 36 0.000 295.783 37 8.949 272.382 38 31.315 261.092 39 55.456 267.790 40 78.607 267.702 41 101.758 267.614 42 124.909 267.526 43 148.059 267.438 44 171.210 267.350 45 194.361 267.262 46 550.000 231.510 47 536.109 231.510 48 522.219 231.510 49 508.328 231.510 50 494.438 231.510 51 494.438 254.660 52 494.438 277.811 53 494.438 300.962 54 494.438 324.113 55 506.015 344.704 56 504.058 368.244 57 489.240 386.640 58 466.657 393.566 59 444.073 386.640 60 429.255 368.244 61 427.298 344.704 62 438.875 324.113 63 438.875 300.962 64 438.875 277.811 65 438.875 254.660 66 438.875 231.510 67 438.875 185.208 68 438.875 162.057 69 438.875 138.906 70 438.875 115.755 71 438.875 92.604 72 438.875 69.453 73 438.875 55.562 74 438.875 41.672 75 438.875 27.781 76 438.875 13.891 77 438.875 0.000