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| Title: | | A THYMINE-LIKE BASE ANALOGUE FORMS WOBBLE PAIRS WITH ADENINE | |
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| Molecular Description: | 5'-D(CpApCpGp(C46)pG)-3') |
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| Structural Features: | Z DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A, B: | |
(DC) (DA) (DC) (DG) (C46) (DG)
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| Primary Citation: | Schuerman, G.S., Van Meervelt, L., Loakes, D., Brown, D.M., Kong Thoo Lin, P., Moore, M.H., Salisbury, S.A.
A thymine-like base analogue forms wobble pairs with adenine in a Z-DNA duplex.
J.Mol.Biol.
, 282,
pp. 1005 - 1011, 1998.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 17.338 | b = 31.432 | c = 44.486 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, SITTING DROP |
| Drop: | | Na Cacodylate, MgCl2, SPERMINE, MPD |
| Reservoir: | | MPD |
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| Refinement: | The structure was refined using the SHELXL-93 program.
The R value is
15.5
for 3696 reflections
in the resolution range 10.000 to
1.500 Ångstroms
with Fobs > 4.000 sigma(Fobs).
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