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| Title: | | CRYSTAL STRUCTURE OF A COPPER-MEDIATED BASE PAIR IN DNA | |
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| Molecular Description: | 5'-D(CpGpCpGp(DPY)pApTp(DRP)pCpGpCpG)-3' |
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| Structural Features: | Z DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A, B: | |
(DC) (DG) (DC) (DG) (DPY) (DA) (DT) (DRP) (DC) (DG) (DC) (DG)
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| Primary Citation: | Atwell, S., Meggers, E., Spraggon, G., Schultz, P.G.
Structure of a Copper-Mediated Base Pair in DNA
J.Am.Chem.Soc.
, 123,
pp. 12364 - 12367, 2001.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
1
21
1
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| Cell Constants: |
| a = 25.343 | b = 34.359 | c = 31.093 | (Ångstroms) |
 = 90.00 |  = 101.13 |  = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, HANGING DROP |
| Drop: | | MPD, Na Cacodylate, Spermine tetra-HCl, NaCl, MgCl2 |
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| Refinement: | The structure was refined using the CNS program.
The R value is
16.9
for 8520 reflections
in the resolution range 50 to
1.5 Ångstroms
with I > 0 sigma(I).
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