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| Title: | | THE LOW-TEMPERATURE CRYSTAL STRUCTURE OF THE PURE-SPERMINE FORM OF Z-DNA REVEALS BINDING OF A SPERMINE MOLECULE IN THE MINOR GROOVE | |
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| Molecular Description: | 5'-D(CpGpCpGpCpG)-3'
SPERMINE
-110C |
 |
| Structural Features: | Z DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A, B: | |
(DC) (DG) (DC) (DG) (DC) (DG)
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| Primary Citation: | Bancroft, D., Williams, L.D., Rich, A., Egli, M.
The low-temperature crystal structure of the pure-spermine form of Z-DNA reveals binding of a spermine molecule in the minor groove.
Biochemistry
, 33,
pp. 1073 - 1086, 1994.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 18.265 | b = 30.690 | c = 42.460 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, SITTING DROP |
| Drop: | | WATER, SPERMINE |
| Reservoir: | | WATER, MPD |
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| Refinement: | The structure was refined using the PROLSQ (MODIFIED BY G.J.QUIGLEY) program.
The R value is
18
for 9575 reflections
in the resolution range 5.000 to
1.000 Ångstroms
with Fobs > 2.000 sigma(Fobs).
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