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| Title: |  | CRYSTAL AND MOLECULAR STRUCTURE OF A DNA DUPLEX CONTAINING THE CARCINOGENIC LESION O6-METHYLGUANINE |  |
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| Molecular Description: | 5'-D(CpGpCp(6OG)pCpG)-3' |
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| Structural Features: | Z DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DC) (DG) (DC) (6OG) (DC) (DG) |
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| Primary Citation: | Ginell, S.L., Kuzmich, S., Jones, R.A., Berman, H.M.
Crystal and molecular structure of a DNA duplex containing the carcinogenic lesion O6-methylguanine.
Biochemistry
, 29,
pp. 10461 - 10465, 1990.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 17.850 | b = 30.870 | c = 43.980 | (Ångstroms) |
= 90.00 | = 90.00 | = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the NUCLSQ program.
The R value is
19.0
for 1217 reflections
in the resolution range 8.000 to
1.900 Ångstroms
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