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| Title: | | CONFORMATIONAL PERTURBATION OF THE ANTICANCER NUCLEOSIDE ARABINOSYLCYTOSINE ON Z-DNA: MOLECULAR STRUCTURE OF (ARAC-DG)3 AT 1.3 ANGSTROMS RESOLUTION | |
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| Molecular Description: | DNA(5'-ARA(*CP*)-D(*GP*)-ARA(*CP*)-D(*GP*)-ARA(*CP*)-D(*GP)-3') |
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| Structural Features: | Z DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Primary Citation: | H. Zhang, G.A. Van Der Marel, J.H. Van Boom, A. H. -J. Wang
Conformational Perturbation of the Anticancer Nucleoside Arabinosylcytosine on Z-DNA: Molecular Structure of (araC-dG)3 at 1.3 Angstroms Resolution
Biopolymers
, 32,
pp. 1559-1569, 1992.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
651
21
21
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| Cell Constants: |
| a = 17.960 | b = 17.960 | c = 43.220 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
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| Crystallization Conditions: |
| Methcomputing.od: | | VAPOR DIFFUSION |
| Drop: | | WATER, MPD, Na Cacodylate, MgCl2, MaCl |
| Reservoir: | | WATER, MPD |
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| Refinement: | The structure was refined using the NUCLSQ program.
The R value is
28.7
for 737 reflections
in the resolution range 10.000 to 1.300 Å.
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