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| Title: | | CRYSTAL STRUCTURE AT 1.5 ANGSTROMS RESOLUTION OF D(CGCICICG), AN OCTANUCLEOTIDE CONTAINING INOSINE, AND ITS COMPARISON WITH D(CGCG) AND D(CGCGCG) STRUCTURES | |
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| Molecular Description: | 5'-D(CpGpCpIpCpIpCpG)-3' |
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| Structural Features: | Z DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A, B: | |
(DC) (DG)
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| Chains | C, D: | |
(DC) (DG) (DC) (DG)
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| Primary Citation: | Kumar, V.D., Harrison, R.W., Andrews, L.C., Weber, I.T.
Crystal structure at 1.5-A resolution of d(CGCICICG), an octanucleotide containing inosine, and its comparison with d(CGCG) and d(CGCGCG) structures.
Biochemistry
, 31,
pp. 1541 - 1550, 1992.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
65
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| Cell Constants: |
| a = 31.000 | b = 31.000 | c = 43.700 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, HANGING DROP |
| Drop: | | WATER, MPD, SPERMINE, Mg ACETATE |
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| Refinement: | The structure was refined using the X-PLOR, NUCLSQ program.
The R value is
22.5
for 2503 reflections
in the resolution range 5.000 to
1.500 Ångstroms
with Fobs > 3.000 sigma(Fobs).
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