HEADER RNA 12-APR-00 XXXX TITLE CRYSTAL STRUCTURE OF A VITAMIN B12 BINDING RNA APTAMER WITH LIGAND AT TITLE 2 2.3 A KEYWDS B12 BINDING RNA, VITAMIN B12, COBALAMIN, RNA EXPDTA X-RAY DIFFRACTION AUTHOR D.SUSSMAN,C.WILSON JRNL AUTH D.SUSSMAN,C.WILSON JRNL TITL A WATER CHANNEL IN THE CORE OF THE VITAMIN B(12) RNA JRNL TITL 2 APTAMER. JRNL REF STRUCTURE FOLD.DES. V. 8 719 2000 JRNL REFN ISSN 0969-2126 JRNL PMID 10903943 JRNL DOI 10.1016/S0969-2126(00)00159-3 SEQRES 1 A 35 G G A A C C G G U G C G C SEQRES 2 A 35 A U A A C C A C C U C A G SEQRES 3 A 35 U G C G A G C A A SEQRES 1 B 35 G G A A C C G G U G C G C SEQRES 2 B 35 A U A A C C A C C U C A G SEQRES 3 B 35 U G C G A G C A A SEQRES 1 C 35 G G A A C C G G U G C G C SEQRES 2 C 35 A U A A C C A C C U C A G SEQRES 3 C 35 U G C G A G C A A SEQRES 1 D 35 G G A A C C G G U G C G C SEQRES 2 D 35 A U A A C C A C C U C A G SEQRES 3 D 35 U G C G A G C A A SEQRES 1 E 35 G G A A C C G G U G C G C SEQRES 2 E 35 A U A A C C A C C U C A G SEQRES 3 E 35 U G C G A G C A A HETNAM CNC CYANOCOBALAMIN FORMUL 6 CNC 5(C63 H89 CO N14 O14 P 2+) FORMUL 11 HOH *725(H2 O) SITE 1 AC1 22 C A 211 A A 214 A A 216 C A 229 SITE 2 AC1 22 G A 230 A A 231 HOH A1151 HOH A1180 SITE 3 AC1 22 HOH A1246 HOH A1253 HOH A1272 HOH A1387 SITE 4 AC1 22 HOH A1459 HOH A1503 HOH A1508 HOH A1673 SITE 5 AC1 22 HOH A1764 HOH B1490 HOH B1612 A D 516 SITE 6 AC1 22 HOH D1189 HOH D1443 SITE 1 AC2 22 HOH A1290 C B 311 A B 314 A B 316 SITE 2 AC2 22 C B 329 G B 330 HOH B1121 HOH B1137 SITE 3 AC2 22 HOH B1266 HOH B1293 HOH B1364 HOH B1420 SITE 4 AC2 22 HOH B1468 HOH B1612 HOH B1707 HOH B1709 SITE 5 AC2 22 HOH B1725 HOH B1777 HOH B1802 CNC D1001 SITE 6 AC2 22 HOH D1256 HOH D1328 SITE 1 AC3 15 C C 411 A C 414 A C 416 C C 429 SITE 2 AC3 15 G C 430 HOH C1109 HOH C1139 HOH C1178 SITE 3 AC3 15 HOH C1211 HOH C1236 HOH C1258 HOH C1271 SITE 4 AC3 15 HOH C1454 A E 117 HOH E1314 SITE 1 AC4 21 A A 216 A A 217 HOH A1246 CNC B 801 SITE 2 AC4 21 HOH B1725 C D 511 A D 514 A D 516 SITE 3 AC4 21 C D 529 G D 530 HOH D1107 HOH D1143 SITE 4 AC4 21 HOH D1168 HOH D1232 HOH D1255 HOH D1256 SITE 5 AC4 21 HOH D1288 HOH D1328 HOH D1332 HOH D1409 SITE 6 AC4 21 HOH D1591 SITE 1 AC5 13 A C 417 HOH C1211 C E 111 A E 114 SITE 2 AC5 13 A E 116 C E 129 G E 130 HOH E1281 SITE 3 AC5 13 HOH E1321 HOH E1585 HOH E1754 HOH E1759 SITE 4 AC5 13 HOH E1778 CRYST1 91.270 98.080 217.970 90.00 90.00 90.00 I 2 2 2 40 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.010957 0.000000 0.000000 0.00000 SCALE2 0.000000 0.010196 0.000000 0.00000 SCALE3 0.000000 0.000000 0.004588 0.00000 MODEL 1 ATOM 1 OP3 G A 201 40.359 45.525 45.761 1.00 48.04 O ATOM 2 P G A 201 40.206 44.013 45.948 1.00 48.16 P ATOM 3 OP1 G A 201 39.869 43.603 47.386 1.00 46.91 O ATOM 4 OP2 G A 201 41.426 43.299 45.358 1.00 47.66 O ATOM 5 O5' G A 201 38.975 43.597 44.967 1.00 46.17 O ATOM 6 C5' G A 201 39.238 43.310 43.591 1.00 44.92 C ATOM 7 C4' G A 201 38.237 42.307 43.050 1.00 44.05 C ATOM 8 O4' G A 201 38.376 41.010 43.698 1.00 43.15 O ATOM 9 C3' G A 201 36.775 42.664 43.258 1.00 43.55 C ATOM 10 O3' G A 201 36.348 43.654 42.329 1.00 43.91 O ATOM 11 C2' G A 201 36.090 41.308 43.091 1.00 42.97 C ATOM 12 O2' G A 201 35.936 40.888 41.745 1.00 42.95 O ATOM 13 C1' G A 201 37.089 40.394 43.811 1.00 42.03 C ATOM 14 N9 G A 201 36.746 40.343 45.224 1.00 40.10 N ATOM 15 C8 G A 201 37.530 40.762 46.270 1.00 39.39 C ATOM 16 N7 G A 201 36.927 40.688 47.424 1.00 38.66 N ATOM 17 C5 G A 201 35.676 40.168 47.123 1.00 38.36 C ATOM 18 C6 G A 201 34.580 39.894 47.970 1.00 37.88 C ATOM 19 O6 G A 201 34.492 40.064 49.191 1.00 37.48 O ATOM 20 N1 G A 201 33.503 39.384 47.265 1.00 37.35 N ATOM 21 C2 G A 201 33.477 39.162 45.916 1.00 37.77 C ATOM 22 N2 G A 201 32.322 38.650 45.437 1.00 37.02 N ATOM 23 N3 G A 201 34.503 39.421 45.098 1.00 38.14 N ATOM 24 C4 G A 201 35.559 39.924 45.771 1.00 38.86 C ATOM 25 P G A 202 35.437 44.891 42.842 1.00 44.23 P ATOM 26 OP1 G A 202 35.303 45.809 41.677 1.00 44.06 O ATOM 27 OP2 G A 202 35.987 45.411 44.143 1.00 43.63 O ATOM 28 O5' G A 202 34.001 44.233 43.049 1.00 43.12 O ATOM 29 C5' G A 202 33.402 43.518 41.973 1.00 42.27 C ATOM 30 C4' G A 202 32.085 42.929 42.400 1.00 41.77 C ATOM 31 O4' G A 202 32.294 41.831 43.333 1.00 40.97 O ATOM 32 C3' G A 202 31.174 43.878 43.158 1.00 41.61 C ATOM 33 O3' G A 202 30.541 44.788 42.268 1.00 42.41 O ATOM 34 C2' G A 202 30.235 42.904 43.855 1.00 40.85 C ATOM 35 O2' G A 202 29.310 42.328 42.951 1.00 41.12 O ATOM 36 C1' G A 202 31.224 41.807 44.270 1.00 39.72 C ATOM 37 N9 G A 202 31.775 42.047 45.598 1.00 37.88 N ATOM 38 C8 G A 202 33.010 42.552 45.919 1.00 37.09 C ATOM 39 N7 G A 202 33.197 42.665 47.206 1.00 36.21 N ATOM 40 C5 G A 202 32.012 42.201 47.763 1.00 35.98 C ATOM 41 C6 G A 202 31.613 42.077 49.114 1.00 35.39 C ATOM 42 O6 G A 202 32.249 42.346 50.138 1.00 35.11 O ATOM 43 N1 G A 202 30.327 41.572 49.218 1.00 34.94 N ATOM 44 C2 G A 202 29.531 41.212 48.165 1.00 35.19 C ATOM 45 N2 G A 202 28.317 40.731 48.467 1.00 34.72 N ATOM 46 N3 G A 202 29.891 41.312 46.910 1.00 35.67 N ATOM 47 C4 G A 202 31.132 41.814 46.781 1.00 36.52 C ATOM 48 P A A 203 30.030 46.219 42.814 1.00 43.38 P ATOM 49 OP1 A A 203 29.800 47.024 41.581 1.00 42.99 O ATOM 50 OP2 A A 203 30.942 46.749 43.877 1.00 42.34 O ATOM 51 O5' A A 203 28.621 45.851 43.480 1.00 42.32 O ATOM 52 C5' A A 203 27.648 45.123 42.731 1.00 41.74 C ATOM 53 C4' A A 203 26.458 44.777 43.598 1.00 41.61 C ATOM 54 O4' A A 203 26.778 43.701 44.520 1.00 41.38 O ATOM 55 C3' A A 203 25.952 45.900 44.486 1.00 41.58 C ATOM 56 O3' A A 203 25.127 46.789 43.750 1.00 41.87 O ATOM 57 C2' A A 203 25.184 45.137 45.556 1.00 41.46 C ATOM 58 O2' A A 203 23.914 44.730 45.081 1.00 41.82 O ATOM 59 C1' A A 203 26.081 43.904 45.748 1.00 41.06 C ATOM 60 N9 A A 203 27.071 44.074 46.817 1.00 40.24 N ATOM 61 C8 A A 203 28.359 44.550 46.716 1.00 39.83 C ATOM 62 N7 A A 203 28.988 44.626 47.864 1.00 39.50 N ATOM 63 C5 A A 203 28.059 44.157 48.782 1.00 39.50 C ATOM 64 C6 A A 203 28.110 43.990 50.177 1.00 39.39 C ATOM 65 N6 A A 203 29.185 44.287 50.921 1.00 38.99 N ATOM 66 N1 A A 203 27.006 43.505 50.793 1.00 39.35 N ATOM 67 C2 A A 203 25.934 43.207 50.045 1.00 39.74 C ATOM 68 N3 A A 203 25.766 43.317 48.724 1.00 39.71 N ATOM 69 C4 A A 203 26.878 43.806 48.149 1.00 39.76 C ATOM 70 P A A 204 24.849 48.269 44.309 1.00 42.09 P ATOM 71 OP1 A A 204 23.918 48.915 43.344 1.00 42.05 O ATOM 72 OP2 A A 204 26.137 48.932 44.624 1.00 42.14 O ATOM 73 O5' A A 204 24.094 48.023 45.697 1.00 42.79 O ATOM 74 C5' A A 204 22.784 47.440 45.732 1.00 43.74 C ATOM 75 C4' A A 204 22.341 47.186 47.164 1.00 44.42 C ATOM 76 O4' A A 204 23.181 46.171 47.781 1.00 44.18 O ATOM 77 C3' A A 204 22.462 48.361 48.120 1.00 44.87 C ATOM 78 O3' A A 204 21.423 49.323 47.963 1.00 46.28 O ATOM 79 C2' A A 204 22.452 47.666 49.481 1.00 44.34 C ATOM 80 O2' A A 204 21.179 47.220 49.908 1.00 44.30 O ATOM 81 C1' A A 204 23.306 46.437 49.180 1.00 43.84 C ATOM 82 N9 A A 204 24.706 46.709 49.484 1.00 43.03 N ATOM 83 C8 A A 204 25.654 47.199 48.627 1.00 42.97 C ATOM 84 N7 A A 204 26.818 47.406 49.190 1.00 42.71 N ATOM 85 C5 A A 204 26.628 47.009 50.503 1.00 42.43 C ATOM 86 C6 A A 204 27.482 46.991 51.595 1.00 42.37 C ATOM 87 N6 A A 204 28.757 47.400 51.514 1.00 42.34 N ATOM 88 N1 A A 204 26.994 46.541 52.781 1.00 42.03 N ATOM 89 C2 A A 204 25.724 46.134 52.826 1.00 42.01 C ATOM 90 N3 A A 204 24.814 46.100 51.849 1.00 42.50 N ATOM 91 C4 A A 204 25.338 46.563 50.699 1.00 42.70 C ATOM 92 P C A 205 21.399 50.626 48.927 1.00 47.62 P ATOM 93 OP1 C A 205 20.062 51.260 48.730 1.00 48.00 O ATOM 94 OP2 C A 205 22.642 51.444 48.747 1.00 47.66 O ATOM 95 O5' C A 205 21.433 50.023 50.394 1.00 46.39 O ATOM 96 C5' C A 205 21.436 50.863 51.502 1.00 45.64 C ATOM 97 C4' C A 205 21.332 50.039 52.741 1.00 45.43 C ATOM 98 O4' C A 205 22.382 49.040 52.741 1.00 45.07 O ATOM 99 C3' C A 205 21.561 50.834 54.006 1.00 45.57 C ATOM 100 O3' C A 205 20.371 51.537 54.342 1.00 45.81 O ATOM 101 C2' C A 205 22.034 49.766 54.979 1.00 45.38 C ATOM 102 O2' C A 205 20.955 48.998 55.470 1.00 45.93 O ATOM 103 C1' C A 205 22.908 48.901 54.057 1.00 44.60 C ATOM 104 N1 C A 205 24.341 49.282 54.017 1.00 43.40 N ATOM 105 C2 C A 205 25.108 49.159 55.172 1.00 43.01 C ATOM 106 O2 C A 205 24.562 48.763 56.210 1.00 43.16 O ATOM 107 N3 C A 205 26.429 49.471 55.130 1.00 42.57 N ATOM 108 C4 C A 205 26.978 49.891 53.989 1.00 42.40 C ATOM 109 N4 C A 205 28.286 50.171 53.982 1.00 42.20 N ATOM 110 C5 C A 205 26.213 50.042 52.803 1.00 42.49 C ATOM 111 C6 C A 205 24.911 49.732 52.862 1.00 42.90 C ATOM 112 P C A 206 20.447 53.121 54.611 1.00 45.60 P ATOM 113 OP1 C A 206 19.056 53.629 54.748 1.00 45.80 O ATOM 114 OP2 C A 206 21.343 53.692 53.549 1.00 45.20 O ATOM 115 O5' C A 206 21.107 53.132 56.058 1.00 44.44 O ATOM 116 C5' C A 206 20.512 52.338 57.077 1.00 43.17 C ATOM 117 C4' C A 206 21.295 52.441 58.347 1.00 42.32 C ATOM 118 O4' C A 206 22.475 51.612 58.266 1.00 42.26 O ATOM 119 C3' C A 206 21.835 53.824 58.647 1.00 42.09 C ATOM 120 O3' C A 206 20.844 54.663 59.213 1.00 41.81 O ATOM 121 C2' C A 206 22.966 53.508 59.608 1.00 42.08 C ATOM 122 O2' C A 206 22.462 53.205 60.896 1.00 42.13 O ATOM 123 C1' C A 206 23.544 52.239 58.970 1.00 41.69 C ATOM 124 N1 C A 206 24.656 52.475 58.018 1.00 40.90 N ATOM 125 C2 C A 206 25.967 52.591 58.513 1.00 40.59 C ATOM 126 O2 C A 206 26.162 52.503 59.731 1.00 40.74 O ATOM 127 N3 C A 206 26.987 52.790 57.653 1.00 40.04 N ATOM 128 C4 C A 206 26.747 52.870 56.348 1.00 40.09 C ATOM 129 N4 C A 206 27.789 53.067 55.543 1.00 40.13 N ATOM 130 C5 C A 206 25.429 52.754 55.811 1.00 40.19 C ATOM 131 C6 C A 206 24.422 52.564 56.675 1.00 40.60 C ATOM 132 P G A 207 20.895 56.248 58.941 1.00 41.49 P ATOM 133 OP1 G A 207 19.666 56.850 59.541 1.00 41.59 O ATOM 134 OP2 G A 207 21.173 56.444 57.492 1.00 41.44 O ATOM 135 O5' G A 207 22.151 56.717 59.807 1.00 41.06 O ATOM 136 C5' G A 207 22.184 56.490 61.220 1.00 40.18 C ATOM 137 C4' G A 207 23.559 56.797 61.788 1.00 39.41 C ATOM 138 O4' G A 207 24.529 55.787 61.386 1.00 39.19 O ATOM 139 C3' G A 207 24.191 58.099 61.328 1.00 39.02 C ATOM 140 O3' G A 207 23.665 59.216 62.025 1.00 38.88 O ATOM 141 C2' G A 207 25.657 57.860 61.649 1.00 38.72 C ATOM 142 O2' G A 207 25.900 57.944 63.037 1.00 38.67 O ATOM 143 C1' G A 207 25.811 56.397 61.223 1.00 38.60 C ATOM 144 N9 G A 207 26.222 56.286 59.819 1.00 37.81 N ATOM 145 C8 G A 207 25.443 55.947 58.732 1.00 37.26 C ATOM 146 N7 G A 207 26.104 55.958 57.601 1.00 36.90 N ATOM 147 C5 G A 207 27.400 56.314 57.963 1.00 36.61 C ATOM 148 C6 G A 207 28.571 56.475 57.170 1.00 36.14 C ATOM 149 O6 G A 207 28.704 56.331 55.948 1.00 35.36 O ATOM 150 N1 G A 207 29.663 56.845 57.945 1.00 35.77 N ATOM 151 C2 G A 207 29.641 57.047 59.307 1.00 36.18 C ATOM 152 N2 G A 207 30.800 57.420 59.878 1.00 35.88 N ATOM 153 N3 G A 207 28.564 56.897 60.057 1.00 36.59 N ATOM 154 C4 G A 207 27.488 56.526 59.326 1.00 37.08 C ATOM 155 P G A 208 23.390 60.595 61.231 1.00 39.05 P ATOM 156 OP1 G A 208 22.731 61.476 62.243 1.00 38.88 O ATOM 157 OP2 G A 208 22.730 60.346 59.909 1.00 38.28 O ATOM 158 O5' G A 208 24.858 61.162 60.916 1.00 38.21 O ATOM 159 C5' G A 208 25.782 61.389 61.980 1.00 36.33 C ATOM 160 C4' G A 208 27.200 61.482 61.459 1.00 35.22 C ATOM 161 O4' G A 208 27.632 60.239 60.834 1.00 34.35 O ATOM 162 C3' G A 208 27.476 62.502 60.371 1.00 34.46 C ATOM 163 O3' G A 208 27.500 63.822 60.864 1.00 34.66 O ATOM 164 C2' G A 208 28.856 62.053 59.906 1.00 33.82 C ATOM 165 O2' G A 208 29.845 62.345 60.883 1.00 33.31 O ATOM 166 C1' G A 208 28.660 60.534 59.879 1.00 33.14 C ATOM 167 N9 G A 208 28.253 60.060 58.551 1.00 31.75 N ATOM 168 C8 G A 208 27.001 59.634 58.153 1.00 31.28 C ATOM 169 N7 G A 208 26.949 59.294 56.889 1.00 30.19 N ATOM 170 C5 G A 208 28.244 59.501 56.419 1.00 30.14 C ATOM 171 C6 G A 208 28.806 59.309 55.110 1.00 29.69 C ATOM 172 O6 G A 208 28.254 58.893 54.065 1.00 28.64 O ATOM 173 N1 G A 208 30.155 59.658 55.089 1.00 29.50 N ATOM 174 C2 G A 208 30.877 60.110 56.171 1.00 29.28 C ATOM 175 N2 G A 208 32.165 60.395 55.950 1.00 28.89 N ATOM 176 N3 G A 208 30.376 60.273 57.377 1.00 29.74 N ATOM 177 C4 G A 208 29.064 59.964 57.431 1.00 30.65 C ATOM 178 P U A 209 27.214 65.056 59.856 1.00 35.08 P ATOM 179 OP1 U A 209 27.153 66.299 60.676 1.00 35.33 O ATOM 180 OP2 U A 209 26.066 64.700 58.975 1.00 35.61 O ATOM 181 O5' U A 209 28.526 65.152 58.957 1.00 34.20 O ATOM 182 C5' U A 209 29.767 65.457 59.568 1.00 33.41 C ATOM 183 C4' U A 209 30.852 65.509 58.531 1.00 32.78 C ATOM 184 O4' U A 209 31.127 64.178 58.009 1.00 32.68 O ATOM 185 C3' U A 209 30.535 66.327 57.291 1.00 32.42 C ATOM 186 O3' U A 209 30.665 67.723 57.538 1.00 32.34 O ATOM 187 C2' U A 209 31.565 65.792 56.305 1.00 32.11 C ATOM 188 O2' U A 209 32.863 66.297 56.552 1.00 31.91 O ATOM 189 C1' U A 209 31.549 64.294 56.653 1.00 31.96 C ATOM 190 N1 U A 209 30.586 63.599 55.788 1.00 31.22 N ATOM 191 C2 U A 209 31.039 63.205 54.564 1.00 30.93 C ATOM 192 O2 U A 209 32.222 63.322 54.240 1.00 30.26 O ATOM 193 N3 U A 209 30.077 62.675 53.729 1.00 30.86 N ATOM 194 C4 U A 209 28.738 62.487 54.009 1.00 31.06 C ATOM 195 O4 U A 209 27.981 62.042 53.133 1.00 31.11 O ATOM 196 C5 U A 209 28.356 62.876 55.330 1.00 31.03 C ATOM 197 C6 U A 209 29.275 63.399 56.157 1.00 31.22 C ATOM 198 P G A 210 29.699 68.756 56.773 1.00 32.15 P ATOM 199 OP1 G A 210 29.834 70.049 57.480 1.00 32.82 O ATOM 200 OP2 G A 210 28.343 68.150 56.592 1.00 32.46 O ATOM 201 O5' G A 210 30.344 68.917 55.324 1.00 31.37 O ATOM 202 C5' G A 210 31.654 69.438 55.155 1.00 29.43 C ATOM 203 C4' G A 210 31.744 70.195 53.848 1.00 28.48 C ATOM 204 O4' G A 210 31.722 69.295 52.714 1.00 27.31 O ATOM 205 C3' G A 210 30.582 71.118 53.538 1.00 28.02 C ATOM 206 O3' G A 210 30.660 72.317 54.286 1.00 29.13 O ATOM 207 C2' G A 210 30.811 71.401 52.066 1.00 27.13 C ATOM 208 O2' G A 210 31.811 72.378 51.926 1.00 26.35 O ATOM 209 C1' G A 210 31.341 70.043 51.569 1.00 26.53 C ATOM 210 N9 G A 210 30.339 69.294 50.812 1.00 25.13 N ATOM 211 C8 G A 210 29.041 69.026 51.191 1.00 24.45 C ATOM 212 N7 G A 210 28.351 68.421 50.268 1.00 23.61 N ATOM 213 C5 G A 210 29.253 68.261 49.220 1.00 23.71 C ATOM 214 C6 G A 210 29.077 67.679 47.935 1.00 22.98 C ATOM 215 O6 G A 210 28.055 67.173 47.456 1.00 22.71 O ATOM 216 N1 G A 210 30.246 67.720 47.192 1.00 22.24 N ATOM 217 C2 G A 210 31.440 68.242 47.627 1.00 22.68 C ATOM 218 N2 G A 210 32.463 68.172 46.763 1.00 22.01 N ATOM 219 N3 G A 210 31.618 68.788 48.816 1.00 22.89 N ATOM 220 C4 G A 210 30.491 68.769 49.554 1.00 23.82 C ATOM 221 P C A 211 29.312 73.104 54.674 1.00 29.80 P ATOM 222 OP1 C A 211 29.813 74.296 55.417 1.00 30.17 O ATOM 223 OP2 C A 211 28.370 72.153 55.333 1.00 29.30 O ATOM 224 O5' C A 211 28.717 73.574 53.273 1.00 29.76 O ATOM 225 C5' C A 211 28.742 74.952 52.906 1.00 30.13 C ATOM 226 C4' C A 211 29.616 75.198 51.683 1.00 30.42 C ATOM 227 O4' C A 211 29.068 74.548 50.527 1.00 30.35 O ATOM 228 C3' C A 211 29.674 76.668 51.296 1.00 31.02 C ATOM 229 O3' C A 211 30.759 77.300 51.959 1.00 32.26 O ATOM 230 C2' C A 211 29.720 76.673 49.760 1.00 30.64 C ATOM 231 O2' C A 211 30.925 77.216 49.276 1.00 31.10 O ATOM 232 C1' C A 211 29.566 75.197 49.383 1.00 30.25 C ATOM 233 N1 C A 211 28.637 74.918 48.271 1.00 29.61 N ATOM 234 C2 C A 211 29.153 74.543 47.017 1.00 29.44 C ATOM 235 O2 C A 211 30.391 74.565 46.836 1.00 28.94 O ATOM 236 N3 C A 211 28.290 74.176 46.034 1.00 29.11 N ATOM 237 C4 C A 211 26.967 74.198 46.259 1.00 29.42 C ATOM 238 N4 C A 211 26.145 73.795 45.269 1.00 28.92 N ATOM 239 C5 C A 211 26.423 74.627 47.506 1.00 29.16 C ATOM 240 C6 C A 211 27.285 74.977 48.470 1.00 29.55 C ATOM 241 P G A 212 30.514 77.947 53.424 1.00 34.56 P ATOM 242 OP1 G A 212 31.526 77.278 54.300 1.00 33.62 O ATOM 243 OP2 G A 212 29.034 77.933 53.826 1.00 33.48 O ATOM 244 O5' G A 212 30.890 79.493 53.259 1.00 33.54 O ATOM 245 C5' G A 212 30.665 80.416 54.344 1.00 32.93 C ATOM 246 C4' G A 212 30.524 81.806 53.808 1.00 32.58 C ATOM 247 O4' G A 212 31.747 82.087 53.087 1.00 32.07 O ATOM 248 C3' G A 212 29.392 81.969 52.806 1.00 32.46 C ATOM 249 O3' G A 212 28.498 80.906 52.590 1.00 32.86 O ATOM 250 C2' G A 212 29.952 82.902 51.742 1.00 32.19 C ATOM 251 O2' G A 212 29.686 84.215 52.160 1.00 33.13 O ATOM 252 C1' G A 212 31.465 82.672 51.845 1.00 31.75 C ATOM 253 N9 G A 212 32.152 81.863 50.849 1.00 31.07 N ATOM 254 C8 G A 212 32.630 80.596 51.057 1.00 30.56 C ATOM 255 N7 G A 212 33.250 80.109 50.024 1.00 30.36 N ATOM 256 C5 G A 212 33.164 81.107 49.061 1.00 30.06 C ATOM 257 C6 G A 212 33.651 81.134 47.726 1.00 29.86 C ATOM 258 O6 G A 212 34.263 80.249 47.118 1.00 29.84 O ATOM 259 N1 G A 212 33.362 82.336 47.098 1.00 29.46 N ATOM 260 C2 G A 212 32.685 83.378 47.681 1.00 29.74 C ATOM 261 N2 G A 212 32.504 84.453 46.906 1.00 29.69 N ATOM 262 N3 G A 212 32.222 83.366 48.920 1.00 29.82 N ATOM 263 C4 G A 212 32.494 82.200 49.549 1.00 30.31 C ATOM 264 P C A 213 26.984 81.190 52.117 1.00 32.05 P ATOM 265 OP1 C A 213 26.226 81.837 53.190 1.00 32.78 O ATOM 266 OP2 C A 213 26.584 79.845 51.647 1.00 33.18 O ATOM 267 O5' C A 213 27.103 82.104 50.821 1.00 31.60 O ATOM 268 C5' C A 213 26.577 83.406 50.776 1.00 30.50 C ATOM 269 C4' C A 213 26.736 83.962 49.386 1.00 30.20 C ATOM 270 O4' C A 213 28.126 83.927 48.975 1.00 30.45 O ATOM 271 C3' C A 213 26.019 83.186 48.296 1.00 30.06 C ATOM 272 O3' C A 213 24.684 83.621 48.310 1.00 29.54 O ATOM 273 C2' C A 213 26.775 83.612 47.039 1.00 29.74 C ATOM 274 O2' C A 213 26.434 84.914 46.636 1.00 30.02 O ATOM 275 C1' C A 213 28.206 83.697 47.568 1.00 30.13 C ATOM 276 N1 C A 213 29.006 82.480 47.338 1.00 29.73 N ATOM 277 C2 C A 213 29.616 82.309 46.105 1.00 29.41 C ATOM 278 O2 C A 213 29.468 83.178 45.241 1.00 30.19 O ATOM 279 N3 C A 213 30.351 81.210 45.876 1.00 29.25 N ATOM 280 C4 C A 213 30.481 80.289 46.825 1.00 29.12 C ATOM 281 N4 C A 213 31.204 79.209 46.538 1.00 29.22 N ATOM 282 C5 C A 213 29.874 80.432 48.104 1.00 29.25 C ATOM 283 C6 C A 213 29.149 81.538 48.315 1.00 29.29 C ATOM 284 P A A 214 23.527 82.647 47.829 1.00 29.95 P ATOM 285 OP1 A A 214 23.566 82.580 46.332 1.00 29.63 O ATOM 286 OP2 A A 214 22.286 83.102 48.518 1.00 29.88 O ATOM 287 O5' A A 214 23.921 81.227 48.434 1.00 28.57 O ATOM 288 C5' A A 214 22.953 80.185 48.471 1.00 27.13 C ATOM 289 C4' A A 214 23.623 78.835 48.445 1.00 25.94 C ATOM 290 O4' A A 214 24.352 78.665 47.197 1.00 25.35 O ATOM 291 C3' A A 214 24.634 78.582 49.553 1.00 25.56 C ATOM 292 O3' A A 214 24.582 77.186 49.735 1.00 25.72 O ATOM 293 C2' A A 214 25.958 78.969 48.888 1.00 25.09 C ATOM 294 O2' A A 214 27.017 78.270 49.514 1.00 25.12 O ATOM 295 C1' A A 214 25.726 78.445 47.466 1.00 24.70 C ATOM 296 N9 A A 214 26.470 79.056 46.365 1.00 23.67 N ATOM 297 C8 A A 214 26.134 80.221 45.738 1.00 23.88 C ATOM 298 N7 A A 214 26.879 80.496 44.688 1.00 23.42 N ATOM 299 C5 A A 214 27.783 79.442 44.640 1.00 22.81 C ATOM 300 C6 A A 214 28.808 79.117 43.736 1.00 21.88 C ATOM 301 N6 A A 214 29.090 79.833 42.653 1.00 20.97 N ATOM 302 N1 A A 214 29.522 78.009 43.975 1.00 21.98 N ATOM 303 C2 A A 214 29.215 77.266 45.026 1.00 22.29 C ATOM 304 N3 A A 214 28.263 77.446 45.935 1.00 23.11 N ATOM 305 C4 A A 214 27.566 78.567 45.684 1.00 23.09 C ATOM 306 P U A 215 24.573 76.555 51.204 1.00 26.18 P ATOM 307 OP1 U A 215 23.284 76.851 51.861 1.00 26.31 O ATOM 308 OP2 U A 215 25.853 76.946 51.858 1.00 26.56 O ATOM 309 O5' U A 215 24.577 74.982 50.907 1.00 25.48 O ATOM 310 C5' U A 215 23.499 74.377 50.171 1.00 24.40 C ATOM 311 C4' U A 215 23.568 72.860 50.269 1.00 23.72 C ATOM 312 O4' U A 215 24.460 72.351 49.237 1.00 23.46 O ATOM 313 C3' U A 215 24.116 72.327 51.590 1.00 23.45 C ATOM 314 O3' U A 215 23.554 71.055 51.885 1.00 23.03 O ATOM 315 C2' U A 215 25.579 72.051 51.241 1.00 23.33 C ATOM 316 O2' U A 215 26.165 71.065 52.064 1.00 23.25 O ATOM 317 C1' U A 215 25.402 71.487 49.839 1.00 23.49 C ATOM 318 N1 U A 215 26.591 71.378 48.977 1.00 23.57 N ATOM 319 C2 U A 215 26.429 70.701 47.766 1.00 23.68 C ATOM 320 O2 U A 215 25.346 70.220 47.414 1.00 23.63 O ATOM 321 N3 U A 215 27.552 70.606 46.993 1.00 23.13 N ATOM 322 C4 U A 215 28.795 71.107 47.278 1.00 23.53 C ATOM 323 O4 U A 215 29.712 70.955 46.448 1.00 23.03 O ATOM 324 C5 U A 215 28.891 71.805 48.552 1.00 23.50 C ATOM 325 C6 U A 215 27.810 71.909 49.334 1.00 23.27 C ATOM 326 P A A 216 21.969 70.893 52.066 1.00 22.56 P ATOM 327 OP1 A A 216 21.293 72.192 52.214 1.00 22.88 O ATOM 328 OP2 A A 216 21.760 69.825 53.073 1.00 22.25 O ATOM 329 O5' A A 216 21.474 70.397 50.624 1.00 23.47 O ATOM 330 C5' A A 216 21.823 69.108 50.106 1.00 22.61 C ATOM 331 C4' A A 216 20.613 68.454 49.470 1.00 22.36 C ATOM 332 O4' A A 216 20.090 69.296 48.400 1.00 22.83 O ATOM 333 C3' A A 216 20.872 67.108 48.807 1.00 22.02 C ATOM 334 O3' A A 216 20.811 66.057 49.754 1.00 21.17 O ATOM 335 C2' A A 216 19.783 67.055 47.736 1.00 22.28 C ATOM 336 O2' A A 216 18.496 66.746 48.261 1.00 22.04 O ATOM 337 C1' A A 216 19.796 68.505 47.254 1.00 22.24 C ATOM 338 N9 A A 216 20.842 68.772 46.264 1.00 22.11 N ATOM 339 C8 A A 216 21.900 69.648 46.391 1.00 22.05 C ATOM 340 N7 A A 216 22.686 69.695 45.335 1.00 21.83 N ATOM 341 C5 A A 216 22.109 68.780 44.461 1.00 22.16 C ATOM 342 C6 A A 216 22.470 68.358 43.175 1.00 21.87 C ATOM 343 N6 A A 216 23.540 68.811 42.527 1.00 21.51 N ATOM 344 N1 A A 216 21.684 67.445 42.571 1.00 22.21 N ATOM 345 C2 A A 216 20.597 66.990 43.228 1.00 22.31 C ATOM 346 N3 A A 216 20.157 67.304 44.446 1.00 22.47 N ATOM 347 C4 A A 216 20.968 68.213 45.018 1.00 22.11 C ATOM 348 P A A 217 21.889 64.888 49.684 1.00 21.11 P ATOM 349 OP1 A A 217 21.626 63.918 50.783 1.00 20.42 O ATOM 350 OP2 A A 217 23.238 65.562 49.555 1.00 20.39 O ATOM 351 O5' A A 217 21.543 64.152 48.307 1.00 21.39 O ATOM 352 C5' A A 217 20.248 63.607 48.068 1.00 21.29 C ATOM 353 C4' A A 217 20.178 63.039 46.672 1.00 21.41 C ATOM 354 O4' A A 217 20.265 64.118 45.701 1.00 21.83 O ATOM 355 C3' A A 217 21.301 62.093 46.279 1.00 21.32 C ATOM 356 O3' A A 217 20.998 60.769 46.673 1.00 21.85 O ATOM 357 C2' A A 217 21.259 62.183 44.763 1.00 22.01 C ATOM 358 O2' A A 217 20.138 61.485 44.214 1.00 22.08 O ATOM 359 C1' A A 217 20.996 63.679 44.564 1.00 21.64 C ATOM 360 N9 A A 217 22.224 64.465 44.503 1.00 21.30 N ATOM 361 C8 A A 217 22.704 65.314 45.463 1.00 21.44 C ATOM 362 N7 A A 217 23.805 65.938 45.114 1.00 21.35 N ATOM 363 C5 A A 217 24.076 65.450 43.850 1.00 21.31 C ATOM 364 C6 A A 217 25.107 65.718 42.931 1.00 21.42 C ATOM 365 N6 A A 217 26.115 66.588 43.146 1.00 20.41 N ATOM 366 N1 A A 217 25.069 65.057 41.751 1.00 21.91 N ATOM 367 C2 A A 217 24.068 64.197 41.525 1.00 21.53 C ATOM 368 N3 A A 217 23.054 63.863 42.305 1.00 21.82 N ATOM 369 C4 A A 217 23.115 64.530 43.466 1.00 21.49 C ATOM 370 P C A 218 22.161 59.804 47.233 1.00 22.36 P ATOM 371 OP1 C A 218 21.466 58.559 47.638 1.00 22.48 O ATOM 372 OP2 C A 218 22.967 60.554 48.242 1.00 22.45 O ATOM 373 O5' C A 218 23.079 59.522 45.954 1.00 22.70 O ATOM 374 C5' C A 218 22.582 58.775 44.842 1.00 22.67 C ATOM 375 C4' C A 218 23.476 58.961 43.630 1.00 22.79 C ATOM 376 O4' C A 218 23.522 60.368 43.259 1.00 23.03 O ATOM 377 C3' C A 218 24.938 58.584 43.824 1.00 22.95 C ATOM 378 O3' C A 218 25.110 57.188 43.696 1.00 23.61 O ATOM 379 C2' C A 218 25.626 59.384 42.722 1.00 23.23 C ATOM 380 O2' C A 218 25.455 58.853 41.423 1.00 23.74 O ATOM 381 C1' C A 218 24.820 60.685 42.752 1.00 23.17 C ATOM 382 N1 C A 218 25.440 61.702 43.616 1.00 22.57 N ATOM 383 C2 C A 218 26.541 62.427 43.130 1.00 22.45 C ATOM 384 O2 C A 218 26.979 62.189 41.988 1.00 22.37 O ATOM 385 N3 C A 218 27.117 63.354 43.913 1.00 22.06 N ATOM 386 C4 C A 218 26.658 63.566 45.141 1.00 22.02 C ATOM 387 N4 C A 218 27.294 64.466 45.888 1.00 21.34 N ATOM 388 C5 C A 218 25.534 62.860 45.661 1.00 22.09 C ATOM 389 C6 C A 218 24.959 61.942 44.871 1.00 22.35 C ATOM 390 P C A 219 26.145 56.415 44.647 1.00 23.69 P ATOM 391 OP1 C A 219 26.149 55.002 44.261 1.00 23.75 O ATOM 392 OP2 C A 219 25.826 56.773 46.050 1.00 23.97 O ATOM 393 O5' C A 219 27.538 57.041 44.218 1.00 24.10 O ATOM 394 C5' C A 219 28.024 56.873 42.890 1.00 23.97 C ATOM 395 C4' C A 219 29.268 57.693 42.688 1.00 24.03 C ATOM 396 O4' C A 219 28.918 59.093 42.721 1.00 23.88 O ATOM 397 C3' C A 219 30.346 57.553 43.752 1.00 24.55 C ATOM 398 O3' C A 219 31.188 56.425 43.511 1.00 25.28 O ATOM 399 C2' C A 219 31.106 58.860 43.588 1.00 24.15 C ATOM 400 O2' C A 219 31.971 58.833 42.471 1.00 23.47 O ATOM 401 C1' C A 219 29.953 59.831 43.330 1.00 23.95 C ATOM 402 N1 C A 219 29.412 60.374 44.580 1.00 24.01 N ATOM 403 C2 C A 219 30.084 61.420 45.198 1.00 23.96 C ATOM 404 O2 C A 219 31.081 61.883 44.639 1.00 23.02 O ATOM 405 N3 C A 219 29.624 61.900 46.381 1.00 23.67 N ATOM 406 C4 C A 219 28.520 61.377 46.929 1.00 23.82 C ATOM 407 N4 C A 219 28.089 61.879 48.090 1.00 23.23 N ATOM 408 C5 C A 219 27.804 60.315 46.304 1.00 23.74 C ATOM 409 C6 C A 219 28.281 59.849 45.139 1.00 23.96 C ATOM 410 P A A 220 31.710 55.543 44.742 1.00 25.98 P ATOM 411 OP1 A A 220 32.484 54.392 44.186 1.00 26.97 O ATOM 412 OP2 A A 220 30.601 55.291 45.687 1.00 26.58 O ATOM 413 O5' A A 220 32.760 56.504 45.451 1.00 26.59 O ATOM 414 C5' A A 220 33.781 57.115 44.682 1.00 26.35 C ATOM 415 C4' A A 220 34.419 58.226 45.467 1.00 26.79 C ATOM 416 O4' A A 220 33.497 59.342 45.618 1.00 26.66 O ATOM 417 C3' A A 220 34.805 57.874 46.896 1.00 26.72 C ATOM 418 O3' A A 220 36.003 57.106 46.937 1.00 26.46 O ATOM 419 C2' A A 220 34.921 59.260 47.527 1.00 26.44 C ATOM 420 O2' A A 220 36.088 59.904 47.071 1.00 25.99 O ATOM 421 C1' A A 220 33.728 59.973 46.877 1.00 26.58 C ATOM 422 N9 A A 220 32.503 59.874 47.677 1.00 26.57 N ATOM 423 C8 A A 220 31.443 59.017 47.489 1.00 26.56 C ATOM 424 N7 A A 220 30.488 59.144 48.386 1.00 26.05 N ATOM 425 C5 A A 220 30.947 60.156 49.216 1.00 26.30 C ATOM 426 C6 A A 220 30.395 60.755 50.373 1.00 26.31 C ATOM 427 N6 A A 220 29.206 60.398 50.907 1.00 25.60 N ATOM 428 N1 A A 220 31.109 61.737 50.969 1.00 26.00 N ATOM 429 C2 A A 220 32.297 62.088 50.432 1.00 26.26 C ATOM 430 N3 A A 220 32.917 61.602 49.354 1.00 26.19 N ATOM 431 C4 A A 220 32.182 60.624 48.787 1.00 26.44 C ATOM 432 P C A 221 36.306 56.158 48.207 1.00 27.67 P ATOM 433 OP1 C A 221 37.669 55.595 48.001 1.00 27.60 O ATOM 434 OP2 C A 221 35.177 55.258 48.551 1.00 26.94 O ATOM 435 O5' C A 221 36.405 57.164 49.449 1.00 27.78 O ATOM 436 C5' C A 221 37.493 58.087 49.562 1.00 27.77 C ATOM 437 C4' C A 221 37.243 59.055 50.701 1.00 28.16 C ATOM 438 O4' C A 221 35.964 59.719 50.498 1.00 28.02 O ATOM 439 C3' C A 221 37.115 58.437 52.085 1.00 28.12 C ATOM 440 O3' C A 221 38.396 58.197 52.660 1.00 28.68 O ATOM 441 C2' C A 221 36.333 59.509 52.832 1.00 28.19 C ATOM 442 O2' C A 221 37.147 60.614 53.188 1.00 28.19 O ATOM 443 C1' C A 221 35.360 59.975 51.747 1.00 27.85 C ATOM 444 N1 C A 221 34.073 59.268 51.793 1.00 28.17 N ATOM 445 C2 C A 221 33.166 59.624 52.794 1.00 28.25 C ATOM 446 O2 C A 221 33.487 60.513 53.587 1.00 28.45 O ATOM 447 N3 C A 221 31.975 58.991 52.877 1.00 28.20 N ATOM 448 C4 C A 221 31.680 58.021 52.006 1.00 28.22 C ATOM 449 N4 C A 221 30.496 57.413 52.134 1.00 28.33 N ATOM 450 C5 C A 221 32.587 57.635 50.966 1.00 27.81 C ATOM 451 C6 C A 221 33.761 58.283 50.896 1.00 27.69 C ATOM 452 P C A 222 38.587 57.008 53.734 1.00 28.91 P ATOM 453 OP1 C A 222 40.034 56.755 53.895 1.00 29.74 O ATOM 454 OP2 C A 222 37.689 55.886 53.351 1.00 29.58 O ATOM 455 O5' C A 222 38.001 57.596 55.090 1.00 29.81 O ATOM 456 C5' C A 222 38.364 58.872 55.563 1.00 29.93 C ATOM 457 C4' C A 222 37.671 59.134 56.870 1.00 30.79 C ATOM 458 O4' C A 222 36.237 59.127 56.627 1.00 30.49 O ATOM 459 C3' C A 222 37.909 58.093 57.961 1.00 31.35 C ATOM 460 O3' C A 222 37.872 58.738 59.241 1.00 32.81 O ATOM 461 C2' C A 222 36.705 57.172 57.802 1.00 31.11 C ATOM 462 O2' C A 222 36.347 56.418 58.947 1.00 31.33 O ATOM 463 C1' C A 222 35.616 58.184 57.475 1.00 30.55 C ATOM 464 N1 C A 222 34.492 57.577 56.753 1.00 30.11 N ATOM 465 C2 C A 222 33.242 57.527 57.375 1.00 30.00 C ATOM 466 O2 C A 222 33.122 57.989 58.522 1.00 29.92 O ATOM 467 N3 C A 222 32.205 56.972 56.723 1.00 29.71 N ATOM 468 C4 C A 222 32.379 56.472 55.499 1.00 29.85 C ATOM 469 N4 C A 222 31.316 55.926 54.891 1.00 29.84 N ATOM 470 C5 C A 222 33.644 56.507 54.842 1.00 29.80 C ATOM 471 C6 C A 222 34.661 57.065 55.498 1.00 29.89 C ATOM 472 P U A 223 39.246 58.987 60.047 1.00 33.59 P ATOM 473 OP1 U A 223 40.360 59.243 59.101 1.00 34.14 O ATOM 474 OP2 U A 223 39.375 57.873 61.017 1.00 34.24 O ATOM 475 O5' U A 223 38.962 60.338 60.831 1.00 34.21 O ATOM 476 C5' U A 223 38.798 61.558 60.130 1.00 35.12 C ATOM 477 C4' U A 223 38.010 62.538 60.965 1.00 35.73 C ATOM 478 O4' U A 223 36.598 62.201 60.926 1.00 36.32 O ATOM 479 C3' U A 223 38.388 62.616 62.440 1.00 35.96 C ATOM 480 O3' U A 223 38.258 63.959 62.894 1.00 35.62 O ATOM 481 C2' U A 223 37.314 61.767 63.106 1.00 36.40 C ATOM 482 O2' U A 223 37.050 62.199 64.421 1.00 36.66 O ATOM 483 C1' U A 223 36.103 62.088 62.243 1.00 36.91 C ATOM 484 N1 U A 223 35.075 61.035 62.270 1.00 37.44 N ATOM 485 C2 U A 223 33.926 61.273 63.017 1.00 37.66 C ATOM 486 O2 U A 223 33.760 62.302 63.661 1.00 37.77 O ATOM 487 N3 U A 223 32.988 60.273 62.982 1.00 37.83 N ATOM 488 C4 U A 223 33.083 59.083 62.304 1.00 38.24 C ATOM 489 O4 U A 223 32.142 58.285 62.345 1.00 38.52 O ATOM 490 C5 U A 223 34.313 58.906 61.565 1.00 38.28 C ATOM 491 C6 U A 223 35.239 59.870 61.578 1.00 37.60 C ATOM 492 P C A 224 39.587 64.824 63.197 1.00 35.17 P ATOM 493 OP1 C A 224 40.344 64.161 64.303 1.00 35.16 O ATOM 494 OP2 C A 224 39.174 66.249 63.310 1.00 35.00 O ATOM 495 O5' C A 224 40.460 64.653 61.877 1.00 34.37 O ATOM 496 C5' C A 224 41.804 65.099 61.816 1.00 32.03 C ATOM 497 C4' C A 224 42.061 65.721 60.471 1.00 30.74 C ATOM 498 O4' C A 224 43.466 66.109 60.394 1.00 30.12 O ATOM 499 C3' C A 224 41.814 64.796 59.280 1.00 30.01 C ATOM 500 O3' C A 224 41.354 65.561 58.170 1.00 29.13 O ATOM 501 C2' C A 224 43.215 64.260 58.986 1.00 29.64 C ATOM 502 O2' C A 224 43.374 63.871 57.639 1.00 29.38 O ATOM 503 C1' C A 224 44.059 65.498 59.267 1.00 29.06 C ATOM 504 N1 C A 224 45.475 65.258 59.555 1.00 28.02 N ATOM 505 C2 C A 224 46.441 65.956 58.811 1.00 27.49 C ATOM 506 O2 C A 224 46.075 66.709 57.894 1.00 26.72 O ATOM 507 N3 C A 224 47.747 65.787 59.103 1.00 27.35 N ATOM 508 C4 C A 224 48.112 64.943 60.076 1.00 27.67 C ATOM 509 N4 C A 224 49.418 64.809 60.337 1.00 27.88 N ATOM 510 C5 C A 224 47.158 64.198 60.825 1.00 27.48 C ATOM 511 C6 C A 224 45.857 64.387 60.535 1.00 27.68 C ATOM 512 P A A 225 39.765 65.738 57.908 1.00 29.38 P ATOM 513 OP1 A A 225 39.597 66.357 56.557 1.00 28.48 O ATOM 514 OP2 A A 225 39.188 66.428 59.100 1.00 29.10 O ATOM 515 O5' A A 225 39.202 64.249 57.855 1.00 28.75 O ATOM 516 C5' A A 225 39.520 63.378 56.764 1.00 28.41 C ATOM 517 C4' A A 225 38.249 62.908 56.082 1.00 28.17 C ATOM 518 O4' A A 225 37.357 62.322 57.068 1.00 28.35 O ATOM 519 C3' A A 225 37.434 63.998 55.401 1.00 27.82 C ATOM 520 O3' A A 225 37.895 64.121 54.053 1.00 26.88 O ATOM 521 C2' A A 225 36.016 63.422 55.433 1.00 28.33 C ATOM 522 O2' A A 225 35.755 62.501 54.396 1.00 28.40 O ATOM 523 C1' A A 225 36.014 62.635 56.745 1.00 28.85 C ATOM 524 N9 A A 225 35.396 63.308 57.890 1.00 29.97 N ATOM 525 C8 A A 225 35.747 64.509 58.449 1.00 30.10 C ATOM 526 N7 A A 225 35.024 64.835 59.492 1.00 30.62 N ATOM 527 C5 A A 225 34.136 63.782 59.631 1.00 30.64 C ATOM 528 C6 A A 225 33.103 63.525 60.559 1.00 30.90 C ATOM 529 N6 A A 225 32.779 64.347 61.560 1.00 30.44 N ATOM 530 N1 A A 225 32.402 62.377 60.417 1.00 31.40 N ATOM 531 C2 A A 225 32.715 61.559 59.402 1.00 30.98 C ATOM 532 N3 A A 225 33.655 61.697 58.468 1.00 30.97 N ATOM 533 C4 A A 225 34.341 62.840 58.644 1.00 30.44 C ATOM 534 P G A 226 38.438 65.528 53.480 1.00 25.95 P ATOM 535 OP1 G A 226 39.889 65.672 53.721 1.00 26.08 O ATOM 536 OP2 G A 226 37.520 66.614 53.895 1.00 26.66 O ATOM 537 O5' G A 226 38.341 65.335 51.905 1.00 26.36 O ATOM 538 C5' G A 226 37.087 65.119 51.254 1.00 25.28 C ATOM 539 C4' G A 226 36.866 66.186 50.203 1.00 24.82 C ATOM 540 O4' G A 226 35.594 65.933 49.548 1.00 24.68 O ATOM 541 C3' G A 226 36.754 67.589 50.782 1.00 24.45 C ATOM 542 O3' G A 226 36.934 68.601 49.806 1.00 25.08 O ATOM 543 C2' G A 226 35.273 67.672 51.126 1.00 24.62 C ATOM 544 O2' G A 226 34.791 69.011 51.111 1.00 23.79 O ATOM 545 C1' G A 226 34.662 66.908 49.948 1.00 24.60 C ATOM 546 N9 G A 226 33.358 66.285 50.193 1.00 24.46 N ATOM 547 C8 G A 226 32.510 66.519 51.248 1.00 24.61 C ATOM 548 N7 G A 226 31.330 65.993 51.082 1.00 24.50 N ATOM 549 C5 G A 226 31.425 65.328 49.870 1.00 24.71 C ATOM 550 C6 G A 226 30.452 64.582 49.143 1.00 24.70 C ATOM 551 O6 G A 226 29.257 64.357 49.430 1.00 24.43 O ATOM 552 N1 G A 226 30.986 64.071 47.968 1.00 24.85 N ATOM 553 C2 G A 226 32.281 64.235 47.551 1.00 25.11 C ATOM 554 N2 G A 226 32.620 63.641 46.400 1.00 24.70 N ATOM 555 N3 G A 226 33.184 64.928 48.213 1.00 25.12 N ATOM 556 C4 G A 226 32.689 65.450 49.346 1.00 24.70 C ATOM 557 P U A 227 38.335 68.800 49.041 1.00 24.14 P ATOM 558 OP1 U A 227 39.347 67.804 49.455 1.00 24.98 O ATOM 559 OP2 U A 227 38.633 70.223 49.125 1.00 25.26 O ATOM 560 O5' U A 227 37.890 68.419 47.565 1.00 25.45 O ATOM 561 C5' U A 227 38.339 69.130 46.459 1.00 25.71 C ATOM 562 C4' U A 227 37.334 69.060 45.319 1.00 25.74 C ATOM 563 O4' U A 227 35.956 69.107 45.835 1.00 25.52 O ATOM 564 C3' U A 227 37.466 70.308 44.467 1.00 25.67 C ATOM 565 O3' U A 227 36.961 70.089 43.177 1.00 25.43 O ATOM 566 C2' U A 227 36.589 71.270 45.233 1.00 25.50 C ATOM 567 O2' U A 227 36.310 72.475 44.574 1.00 26.68 O ATOM 568 C1' U A 227 35.385 70.364 45.476 1.00 25.71 C ATOM 569 N1 U A 227 34.492 70.853 46.536 1.00 25.79 N ATOM 570 C2 U A 227 33.237 71.307 46.158 1.00 25.80 C ATOM 571 O2 U A 227 32.827 71.248 45.016 1.00 26.71 O ATOM 572 N3 U A 227 32.480 71.838 47.157 1.00 25.62 N ATOM 573 C4 U A 227 32.826 71.955 48.474 1.00 25.83 C ATOM 574 O4 U A 227 32.025 72.475 49.262 1.00 25.70 O ATOM 575 C5 U A 227 34.121 71.435 48.800 1.00 25.69 C ATOM 576 C6 U A 227 34.885 70.906 47.841 1.00 25.78 C ATOM 577 P G A 228 37.817 69.231 42.126 1.00 26.04 P ATOM 578 OP1 G A 228 39.196 68.984 42.663 1.00 25.78 O ATOM 579 OP2 G A 228 37.646 69.957 40.837 1.00 25.72 O ATOM 580 O5' G A 228 37.022 67.841 42.099 1.00 24.79 O ATOM 581 C5' G A 228 37.591 66.694 41.497 1.00 24.24 C ATOM 582 C4' G A 228 36.512 65.739 41.006 1.00 23.90 C ATOM 583 O4' G A 228 35.832 65.125 42.124 1.00 23.47 O ATOM 584 C3' G A 228 35.373 66.325 40.185 1.00 23.28 C ATOM 585 O3' G A 228 35.744 66.538 38.842 1.00 23.09 O ATOM 586 C2' G A 228 34.349 65.209 40.262 1.00 23.24 C ATOM 587 O2' G A 228 34.714 64.151 39.418 1.00 23.22 O ATOM 588 C1' G A 228 34.540 64.710 41.704 1.00 23.20 C ATOM 589 N9 G A 228 33.543 65.197 42.656 1.00 22.82 N ATOM 590 C8 G A 228 33.731 66.112 43.663 1.00 22.59 C ATOM 591 N7 G A 228 32.648 66.341 44.356 1.00 22.60 N ATOM 592 C5 G A 228 31.684 65.537 43.770 1.00 22.36 C ATOM 593 C6 G A 228 30.310 65.361 44.091 1.00 22.35 C ATOM 594 O6 G A 228 29.645 65.912 44.980 1.00 22.26 O ATOM 595 N1 G A 228 29.699 64.440 43.245 1.00 22.37 N ATOM 596 C2 G A 228 30.324 63.787 42.204 1.00 22.23 C ATOM 597 N2 G A 228 29.546 62.961 41.474 1.00 21.69 N ATOM 598 N3 G A 228 31.607 63.940 41.898 1.00 22.18 N ATOM 599 C4 G A 228 32.221 64.822 42.716 1.00 22.53 C ATOM 600 P C A 229 35.228 67.848 38.073 1.00 23.67 P ATOM 601 OP1 C A 229 35.724 67.816 36.670 1.00 23.53 O ATOM 602 OP2 C A 229 35.552 69.028 38.912 1.00 24.38 O ATOM 603 O5' C A 229 33.650 67.670 38.093 1.00 23.90 O ATOM 604 C5' C A 229 33.072 66.470 37.621 1.00 24.30 C ATOM 605 C4' C A 229 31.590 66.411 37.921 1.00 24.44 C ATOM 606 O4' C A 229 31.317 66.028 39.285 1.00 24.15 O ATOM 607 C3' C A 229 30.800 67.688 37.716 1.00 25.09 C ATOM 608 O3' C A 229 30.593 67.825 36.329 1.00 26.34 O ATOM 609 C2' C A 229 29.517 67.389 38.500 1.00 24.79 C ATOM 610 O2' C A 229 28.605 66.513 37.872 1.00 24.38 O ATOM 611 C1' C A 229 30.072 66.600 39.688 1.00 24.27 C ATOM 612 N1 C A 229 30.305 67.426 40.877 1.00 23.55 N ATOM 613 C2 C A 229 29.308 67.518 41.848 1.00 23.34 C ATOM 614 O2 C A 229 28.239 66.908 41.675 1.00 23.09 O ATOM 615 N3 C A 229 29.532 68.265 42.958 1.00 23.66 N ATOM 616 C4 C A 229 30.693 68.908 43.102 1.00 23.77 C ATOM 617 N4 C A 229 30.878 69.638 44.203 1.00 23.17 N ATOM 618 C5 C A 229 31.729 68.829 42.112 1.00 23.68 C ATOM 619 C6 C A 229 31.490 68.090 41.032 1.00 23.46 C ATOM 620 P G A 230 30.573 69.272 35.636 1.00 27.70 P ATOM 621 OP1 G A 230 29.120 69.578 35.536 1.00 28.71 O ATOM 622 OP2 G A 230 31.427 69.317 34.420 1.00 27.33 O ATOM 623 O5' G A 230 31.190 70.320 36.653 1.00 27.63 O ATOM 624 C5' G A 230 31.538 71.620 36.169 1.00 26.91 C ATOM 625 C4' G A 230 32.489 72.284 37.122 1.00 26.54 C ATOM 626 O4' G A 230 31.753 72.754 38.297 1.00 26.15 O ATOM 627 C3' G A 230 33.577 71.366 37.652 1.00 26.35 C ATOM 628 O3' G A 230 34.730 72.160 37.893 1.00 27.80 O ATOM 629 C2' G A 230 32.949 70.833 38.942 1.00 26.09 C ATOM 630 O2' G A 230 33.907 70.409 39.889 1.00 25.87 O ATOM 631 C1' G A 230 32.196 72.068 39.450 1.00 25.44 C ATOM 632 N9 G A 230 31.008 71.824 40.256 1.00 24.19 N ATOM 633 C8 G A 230 29.894 71.142 39.870 1.00 23.47 C ATOM 634 N7 G A 230 28.933 71.193 40.743 1.00 22.79 N ATOM 635 C5 G A 230 29.462 71.930 41.790 1.00 23.04 C ATOM 636 C6 G A 230 28.872 72.317 43.022 1.00 22.96 C ATOM 637 O6 G A 230 27.729 72.074 43.431 1.00 22.58 O ATOM 638 N1 G A 230 29.748 73.052 43.805 1.00 22.43 N ATOM 639 C2 G A 230 31.038 73.383 43.449 1.00 23.26 C ATOM 640 N2 G A 230 31.747 74.118 44.359 1.00 22.37 N ATOM 641 N3 G A 230 31.600 73.027 42.291 1.00 23.21 N ATOM 642 C4 G A 230 30.751 72.307 41.519 1.00 23.69 C ATOM 643 P A A 231 36.129 71.756 37.211 1.00 27.93 P ATOM 644 OP1 A A 231 35.901 70.589 36.311 1.00 28.83 O ATOM 645 OP2 A A 231 37.150 71.656 38.274 1.00 28.79 O ATOM 646 O5' A A 231 36.432 72.995 36.295 1.00 29.46 O ATOM 647 C5' A A 231 36.583 74.256 36.866 1.00 31.26 C ATOM 648 C4' A A 231 35.769 75.274 36.113 1.00 32.59 C ATOM 649 O4' A A 231 34.338 75.006 36.220 1.00 32.60 O ATOM 650 C3' A A 231 35.950 76.666 36.681 1.00 33.50 C ATOM 651 O3' A A 231 37.153 77.239 36.187 1.00 35.28 O ATOM 652 C2' A A 231 34.643 77.359 36.329 1.00 33.29 C ATOM 653 O2' A A 231 34.588 77.853 35.002 1.00 33.40 O ATOM 654 C1' A A 231 33.643 76.216 36.552 1.00 33.10 C ATOM 655 N9 A A 231 33.225 76.137 37.962 1.00 32.70 N ATOM 656 C8 A A 231 33.725 75.270 38.891 1.00 32.53 C ATOM 657 N7 A A 231 33.219 75.428 40.094 1.00 32.54 N ATOM 658 C5 A A 231 32.319 76.468 39.946 1.00 32.32 C ATOM 659 C6 A A 231 31.457 77.108 40.864 1.00 32.26 C ATOM 660 N6 A A 231 31.383 76.767 42.154 1.00 32.14 N ATOM 661 N1 A A 231 30.672 78.113 40.409 1.00 32.36 N ATOM 662 C2 A A 231 30.758 78.438 39.110 1.00 32.34 C ATOM 663 N3 A A 231 31.534 77.898 38.143 1.00 32.90 N ATOM 664 C4 A A 231 32.298 76.910 38.636 1.00 32.51 C ATOM 665 P G A 232 37.726 78.550 36.893 1.00 36.49 P ATOM 666 OP1 G A 232 38.965 78.990 36.185 1.00 37.21 O ATOM 667 OP2 G A 232 37.751 78.337 38.357 1.00 36.51 O ATOM 668 O5' G A 232 36.568 79.594 36.596 1.00 36.97 O ATOM 669 C5' G A 232 36.674 80.885 37.074 1.00 37.79 C ATOM 670 C4' G A 232 35.329 81.530 37.147 1.00 38.02 C ATOM 671 O4' G A 232 34.307 80.594 37.569 1.00 38.01 O ATOM 672 C3' G A 232 35.305 82.617 38.199 1.00 38.18 C ATOM 673 O3' G A 232 35.960 83.739 37.662 1.00 38.99 O ATOM 674 C2' G A 232 33.829 82.723 38.535 1.00 37.89 C ATOM 675 O2' G A 232 33.094 83.442 37.571 1.00 37.90 O ATOM 676 C1' G A 232 33.433 81.247 38.484 1.00 37.64 C ATOM 677 N9 G A 232 33.561 80.582 39.776 1.00 37.08 N ATOM 678 C8 G A 232 34.341 79.493 40.078 1.00 36.78 C ATOM 679 N7 G A 232 34.181 79.080 41.308 1.00 36.70 N ATOM 680 C5 G A 232 33.258 79.965 41.848 1.00 36.34 C ATOM 681 C6 G A 232 32.684 80.020 43.145 1.00 36.31 C ATOM 682 O6 G A 232 32.882 79.276 44.122 1.00 35.71 O ATOM 683 N1 G A 232 31.794 81.072 43.258 1.00 35.93 N ATOM 684 C2 G A 232 31.490 81.957 42.264 1.00 36.18 C ATOM 685 N2 G A 232 30.592 82.910 42.570 1.00 36.07 N ATOM 686 N3 G A 232 32.018 81.918 41.055 1.00 36.38 N ATOM 687 C4 G A 232 32.884 80.905 40.919 1.00 36.50 C ATOM 688 P C A 233 37.154 84.408 38.486 1.00 39.37 P ATOM 689 OP1 C A 233 37.881 85.306 37.548 1.00 39.61 O ATOM 690 OP2 C A 233 37.881 83.322 39.204 1.00 39.13 O ATOM 691 O5' C A 233 36.332 85.321 39.493 1.00 39.41 O ATOM 692 C5' C A 233 35.263 86.111 38.977 1.00 39.29 C ATOM 693 C4' C A 233 34.336 86.521 40.078 1.00 39.44 C ATOM 694 O4' C A 233 33.521 85.400 40.523 1.00 39.13 O ATOM 695 C3' C A 233 35.014 86.986 41.350 1.00 39.61 C ATOM 696 O3' C A 233 35.554 88.290 41.216 1.00 40.47 O ATOM 697 C2' C A 233 33.871 86.875 42.338 1.00 39.39 C ATOM 698 O2' C A 233 32.908 87.868 42.041 1.00 39.41 O ATOM 699 C1' C A 233 33.287 85.518 41.923 1.00 39.13 C ATOM 700 N1 C A 233 33.959 84.381 42.600 1.00 38.45 N ATOM 701 C2 C A 233 33.568 84.041 43.904 1.00 38.19 C ATOM 702 O2 C A 233 32.707 84.738 44.478 1.00 38.05 O ATOM 703 N3 C A 233 34.139 82.967 44.510 1.00 37.98 N ATOM 704 C4 C A 233 35.071 82.261 43.869 1.00 37.90 C ATOM 705 N4 C A 233 35.600 81.199 44.498 1.00 37.65 N ATOM 706 C5 C A 233 35.505 82.605 42.554 1.00 37.90 C ATOM 707 C6 C A 233 34.930 83.662 41.965 1.00 38.07 C ATOM 708 P A A 234 36.912 88.676 42.007 1.00 41.31 P ATOM 709 OP1 A A 234 37.228 90.075 41.581 1.00 41.16 O ATOM 710 OP2 A A 234 37.936 87.608 41.832 1.00 41.15 O ATOM 711 O5' A A 234 36.491 88.642 43.553 1.00 40.61 O ATOM 712 C5' A A 234 35.395 89.433 44.026 1.00 40.20 C ATOM 713 C4' A A 234 34.993 89.018 45.426 1.00 40.12 C ATOM 714 O4' A A 234 34.448 87.672 45.413 1.00 39.53 O ATOM 715 C3' A A 234 36.110 88.964 46.460 1.00 39.90 C ATOM 716 O3' A A 234 36.366 90.255 46.988 1.00 40.39 O ATOM 717 C2' A A 234 35.528 88.017 47.504 1.00 39.63 C ATOM 718 O2' A A 234 34.556 88.615 48.355 1.00 39.71 O ATOM 719 C1' A A 234 34.826 86.999 46.602 1.00 39.09 C ATOM 720 N9 A A 234 35.724 85.913 46.223 1.00 38.59 N ATOM 721 C8 A A 234 36.454 85.768 45.065 1.00 38.11 C ATOM 722 N7 A A 234 37.171 84.670 45.032 1.00 37.96 N ATOM 723 C5 A A 234 36.893 84.055 46.249 1.00 37.73 C ATOM 724 C6 A A 234 37.335 82.868 46.822 1.00 37.52 C ATOM 725 N6 A A 234 38.194 82.025 46.227 1.00 37.71 N ATOM 726 N1 A A 234 36.867 82.556 48.046 1.00 37.23 N ATOM 727 C2 A A 234 36.016 83.387 48.640 1.00 37.25 C ATOM 728 N3 A A 234 35.527 84.528 48.205 1.00 37.70 N ATOM 729 C4 A A 234 36.011 84.810 46.989 1.00 37.97 C ATOM 730 P A A 235 37.872 90.718 47.267 1.00 40.85 P ATOM 731 OP1 A A 235 37.796 92.184 47.550 1.00 41.12 O ATOM 732 OP2 A A 235 38.753 90.234 46.174 1.00 41.03 O ATOM 733 O5' A A 235 38.260 89.952 48.611 1.00 40.71 O ATOM 734 C5' A A 235 37.635 90.298 49.835 1.00 40.43 C ATOM 735 C4' A A 235 37.817 89.200 50.839 1.00 40.48 C ATOM 736 O4' A A 235 37.403 87.947 50.233 1.00 40.40 O ATOM 737 C3' A A 235 39.244 88.933 51.295 1.00 40.60 C ATOM 738 O3' A A 235 39.733 89.869 52.304 1.00 41.14 O ATOM 739 C2' A A 235 39.144 87.500 51.798 1.00 40.10 C ATOM 740 O2' A A 235 38.502 87.438 53.048 1.00 40.34 O ATOM 741 C1' A A 235 38.183 86.893 50.772 1.00 39.95 C ATOM 742 N9 A A 235 38.868 86.219 49.675 1.00 39.34 N ATOM 743 C8 A A 235 39.257 86.747 48.474 1.00 38.94 C ATOM 744 N7 A A 235 39.857 85.885 47.692 1.00 38.95 N ATOM 745 C5 A A 235 39.855 84.707 48.431 1.00 38.72 C ATOM 746 C6 A A 235 40.328 83.414 48.155 1.00 38.56 C ATOM 747 N6 A A 235 40.922 83.078 47.006 1.00 38.63 N ATOM 748 N1 A A 235 40.168 82.467 49.108 1.00 38.54 N ATOM 749 C2 A A 235 39.564 82.805 50.245 1.00 38.33 C ATOM 750 N3 A A 235 39.070 83.981 50.615 1.00 38.70 N ATOM 751 C4 A A 235 39.253 84.900 49.652 1.00 38.75 C TER 752 A A 235 HETATM 753 CO CNC A 701 22.615 74.408 41.383 1.00 33.88 CO HETATM 754 N21 CNC A 701 23.008 73.088 40.045 1.00 32.96 N HETATM 755 N22 CNC A 701 20.898 73.572 41.745 1.00 33.63 N HETATM 756 N23 CNC A 701 22.442 75.833 42.726 1.00 33.79 N HETATM 757 N24 CNC A 701 24.358 75.033 40.956 1.00 33.05 N HETATM 758 C1 CNC A 701 24.239 73.290 39.216 1.00 32.27 C HETATM 759 C20 CNC A 701 23.928 74.176 37.993 1.00 31.97 C HETATM 760 C2 CNC A 701 24.622 71.773 38.782 1.00 31.86 C HETATM 761 C25 CNC A 701 25.464 71.707 37.490 1.00 31.24 C HETATM 762 C26 CNC A 701 25.358 71.079 39.944 1.00 31.66 C HETATM 763 C27 CNC A 701 25.597 69.569 39.870 1.00 31.55 C HETATM 764 O28 CNC A 701 24.694 68.729 39.669 1.00 29.87 O HETATM 765 N29 CNC A 701 26.884 69.203 40.081 1.00 31.86 N HETATM 766 C3 CNC A 701 23.191 71.189 38.668 1.00 32.40 C HETATM 767 C30 CNC A 701 22.376 71.216 37.343 1.00 32.04 C HETATM 768 C31 CNC A 701 22.254 69.792 36.764 1.00 32.30 C HETATM 769 C32 CNC A 701 21.417 69.686 35.526 1.00 32.13 C HETATM 770 O34 CNC A 701 20.285 69.137 35.632 1.00 32.79 O HETATM 771 N33 CNC A 701 21.859 70.157 34.381 1.00 31.46 N HETATM 772 C4 CNC A 701 22.465 71.934 39.794 1.00 32.37 C HETATM 773 C5 CNC A 701 21.229 71.471 40.422 1.00 32.71 C HETATM 774 C35 CNC A 701 20.842 69.993 40.133 1.00 32.52 C HETATM 775 C6 CNC A 701 20.498 72.273 41.311 1.00 33.49 C HETATM 776 C7 CNC A 701 19.173 71.945 42.116 1.00 33.69 C HETATM 777 C36 CNC A 701 18.085 71.162 41.307 1.00 33.48 C HETATM 778 C37 CNC A 701 19.639 71.204 43.426 1.00 33.42 C HETATM 779 C38 CNC A 701 18.508 70.784 44.392 1.00 33.60 C HETATM 780 O39 CNC A 701 18.461 71.271 45.530 1.00 33.42 O HETATM 781 N40 CNC A 701 17.638 69.885 43.965 1.00 33.17 N HETATM 782 C8 CNC A 701 18.654 73.389 42.462 1.00 34.32 C HETATM 783 C41 CNC A 701 17.757 74.051 41.353 1.00 35.73 C HETATM 784 C42 CNC A 701 17.373 75.545 41.498 1.00 37.97 C HETATM 785 C43 CNC A 701 16.552 76.129 40.387 1.00 39.60 C HETATM 786 O44 CNC A 701 15.805 75.456 39.543 1.00 40.77 O HETATM 787 N45 CNC A 701 16.633 77.481 40.263 1.00 40.20 N HETATM 788 C9 CNC A 701 19.984 74.113 42.545 1.00 34.22 C HETATM 789 C10 CNC A 701 20.171 75.225 43.398 1.00 34.28 C HETATM 790 C11 CNC A 701 21.349 75.947 43.516 1.00 34.35 C HETATM 791 C12 CNC A 701 21.650 76.952 44.670 1.00 34.74 C HETATM 792 C46 CNC A 701 22.321 76.192 45.816 1.00 34.37 C HETATM 793 C47 CNC A 701 20.351 77.565 45.283 1.00 34.78 C HETATM 794 C13 CNC A 701 22.661 77.833 44.012 1.00 35.01 C HETATM 795 C48 CNC A 701 22.112 78.968 43.149 1.00 36.40 C HETATM 796 C49 CNC A 701 21.580 80.242 43.894 1.00 38.47 C HETATM 797 C50 CNC A 701 22.283 81.455 43.436 1.00 39.46 C HETATM 798 O51 CNC A 701 23.527 81.521 43.568 1.00 40.68 O HETATM 799 N52 CNC A 701 21.543 82.439 42.878 1.00 40.20 N HETATM 800 C14 CNC A 701 23.328 76.806 43.063 1.00 34.10 C HETATM 801 C15 CNC A 701 24.607 76.943 42.480 1.00 33.88 C HETATM 802 C53 CNC A 701 25.482 78.124 42.970 1.00 33.25 C HETATM 803 C16 CNC A 701 25.125 76.013 41.432 1.00 33.51 C HETATM 804 C17 CNC A 701 26.555 75.940 40.814 1.00 33.20 C HETATM 805 C54 CNC A 701 27.479 75.380 41.921 1.00 32.96 C HETATM 806 C55 CNC A 701 27.185 77.222 40.248 1.00 33.65 C HETATM 807 C56 CNC A 701 26.364 78.046 39.296 1.00 34.62 C HETATM 808 C57 CNC A 701 26.905 79.424 39.174 1.00 35.41 C HETATM 809 O58 CNC A 701 26.685 80.261 40.086 1.00 36.33 O HETATM 810 N59 CNC A 701 27.601 79.697 38.087 1.00 35.81 N HETATM 811 C18 CNC A 701 26.313 74.968 39.626 1.00 32.79 C HETATM 812 C60 CNC A 701 27.549 74.171 39.162 1.00 32.70 C HETATM 813 C61 CNC A 701 28.089 74.700 37.844 1.00 32.89 C HETATM 814 O63 CNC A 701 29.364 74.448 37.613 1.00 33.70 O HETATM 815 N62 CNC A 701 27.347 75.311 37.089 1.00 32.60 N HETATM 816 C19 CNC A 701 25.181 74.110 40.145 1.00 32.58 C HETATM 817 C1P CNC A 701 28.171 81.018 37.875 1.00 36.38 C HETATM 818 C2P CNC A 701 27.166 81.962 37.259 1.00 36.52 C HETATM 819 C3P CNC A 701 27.848 83.245 36.748 1.00 36.61 C HETATM 820 O3 CNC A 701 26.563 81.223 36.111 1.00 36.72 O HETATM 821 O4 CNC A 701 24.397 82.549 35.899 1.00 37.13 O HETATM 822 O5 CNC A 701 24.769 80.312 34.744 1.00 37.11 O HETATM 823 P CNC A 701 25.000 81.168 35.956 1.00 37.13 P HETATM 824 O2 CNC A 701 24.572 80.477 37.306 1.00 36.47 O HETATM 825 C3R CNC A 701 23.176 80.423 37.690 1.00 36.02 C HETATM 826 C2R CNC A 701 22.526 79.116 37.323 1.00 35.91 C HETATM 827 O7R CNC A 701 23.467 78.036 37.381 1.00 35.55 O HETATM 828 C1R CNC A 701 21.494 78.966 38.484 1.00 35.50 C HETATM 829 O6R CNC A 701 22.015 79.704 39.609 1.00 35.81 O HETATM 830 C4R CNC A 701 23.059 80.592 39.175 1.00 36.32 C HETATM 831 C5R CNC A 701 22.767 82.032 39.690 1.00 36.42 C HETATM 832 O8R CNC A 701 21.410 82.509 39.339 1.00 37.79 O HETATM 833 N1B CNC A 701 21.339 77.556 38.891 1.00 35.20 N HETATM 834 C8B CNC A 701 20.437 76.614 38.314 1.00 35.10 C HETATM 835 C2B CNC A 701 22.049 76.903 39.828 1.00 34.48 C HETATM 836 N3B CNC A 701 21.753 75.602 39.951 1.00 34.06 N HETATM 837 C9B CNC A 701 20.718 75.421 38.977 1.00 34.86 C HETATM 838 C4B CNC A 701 19.980 74.241 38.591 1.00 35.05 C HETATM 839 C5B CNC A 701 19.005 74.329 37.581 1.00 35.65 C HETATM 840 C5M CNC A 701 18.232 73.037 37.199 1.00 35.41 C HETATM 841 C6B CNC A 701 18.726 75.562 36.916 1.00 35.69 C HETATM 842 C6M CNC A 701 17.666 75.655 35.802 1.00 35.70 C HETATM 843 C7B CNC A 701 19.465 76.749 37.292 1.00 35.43 C HETATM 844 N1A CNC A 701 23.818 72.531 43.433 1.00 32.35 N HETATM 845 C1A CNC A 701 23.368 73.267 42.676 1.00 33.32 C HETATM 846 O HOH A1100 17.002 64.630 46.944 0.97 5.23 O HETATM 847 O HOH A1102 30.810 75.070 34.682 1.00 5.08 O HETATM 848 O HOH A1103 20.718 73.049 47.066 0.93 2.00 O HETATM 849 O HOH A1104 45.584 62.843 55.963 0.95 9.20 O HETATM 850 O HOH A1117 16.132 70.275 47.465 0.90 7.22 O HETATM 851 O HOH A1123 32.464 53.906 52.456 0.98 15.26 O HETATM 852 O HOH A1124 27.841 68.241 44.960 0.80 10.03 O HETATM 853 O HOH A1125 37.770 79.504 43.067 1.05 21.07 O HETATM 854 O HOH A1128 35.537 69.978 53.724 0.94 13.02 O HETATM 855 O HOH A1130 25.719 70.144 44.079 0.97 17.15 O HETATM 856 O HOH A1132 34.403 66.829 54.368 1.04 19.22 O HETATM 857 O HOH A1142 27.086 53.573 52.879 1.03 19.66 O HETATM 858 O HOH A1145 38.167 69.213 38.408 0.80 33.92 O HETATM 859 O HOH A1151 23.791 72.540 46.362 0.69 12.10 O HETATM 860 O HOH A1153 35.400 74.318 46.527 0.97 17.75 O HETATM 861 O HOH A1156 50.264 62.843 62.516 1.07 26.57 O HETATM 862 O HOH A1165 25.813 39.974 46.738 1.15 21.62 O HETATM 863 O HOH A1166 20.438 59.906 41.492 0.92 12.36 O HETATM 864 O HOH A1167 29.726 55.256 50.271 0.99 26.36 O HETATM 865 O HOH A1172 34.315 74.643 42.622 0.80 17.21 O HETATM 866 O HOH A1174 35.316 63.208 48.758 0.75 13.50 O HETATM 867 O HOH A1180 18.547 79.120 41.862 1.11 21.28 O HETATM 868 O HOH A1183 24.205 67.178 47.838 0.83 18.74 O HETATM 869 O HOH A1186 26.790 58.130 49.531 1.19 27.24 O HETATM 870 O HOH A1191 25.497 68.037 50.216 0.82 16.36 O HETATM 871 O HOH A1208 30.191 66.250 53.381 0.84 29.79 O HETATM 872 O HOH A1213 42.124 79.874 46.426 0.94 33.62 O HETATM 873 O HOH A1217 34.034 77.200 44.604 0.88 32.57 O HETATM 874 O HOH A1221 37.652 61.858 48.368 0.81 16.22 O HETATM 875 O HOH A1222 22.117 61.133 50.823 0.79 24.01 O HETATM 876 O HOH A1228 24.860 62.700 56.495 0.81 31.51 O HETATM 877 O HOH A1233 26.153 65.596 48.601 0.82 11.29 O HETATM 878 O HOH A1235 35.414 72.050 42.055 0.79 16.90 O HETATM 879 O HOH A1237 29.994 59.299 39.287 1.01 22.23 O HETATM 880 O HOH A1239 27.508 71.476 34.754 0.70 21.05 O HETATM 881 O HOH A1246 17.406 67.085 44.803 0.92 34.35 O HETATM 882 O HOH A1250 42.145 64.889 55.297 0.67 17.00 O HETATM 883 O HOH A1253 25.011 77.773 35.350 0.69 15.69 O HETATM 884 O HOH A1260 19.853 77.231 49.025 0.87 25.36 O HETATM 885 O HOH A1272 24.963 83.342 44.447 0.89 36.08 O HETATM 886 O HOH A1279 28.809 57.969 62.442 1.05 40.36 O HETATM 887 O HOH A1283 38.398 54.660 50.524 0.97 36.07 O HETATM 888 O HOH A1287 16.830 73.181 48.426 0.74 17.13 O HETATM 889 O HOH A1290 17.107 69.139 49.827 0.80 25.19 O HETATM 890 O HOH A1294 32.334 70.230 58.183 1.15 63.56 O HETATM 891 O HOH A1301 39.377 74.443 34.719 1.02 24.14 O HETATM 892 O HOH A1312 33.477 67.518 61.406 0.97 27.82 O HETATM 893 O HOH A1315 26.010 71.940 54.623 0.78 33.95 O HETATM 894 O HOH A1318 25.995 65.843 39.327 0.84 18.56 O HETATM 895 O HOH A1319 25.571 60.764 49.639 0.88 29.66 O HETATM 896 O HOH A1322 25.226 79.106 53.925 0.82 22.76 O HETATM 897 O HOH A1327 35.534 54.629 51.544 0.95 27.86 O HETATM 898 O HOH A1338 36.970 80.508 49.874 0.78 27.03 O HETATM 899 O HOH A1345 33.169 77.677 52.840 1.25 41.93 O HETATM 900 O HOH A1347 24.931 50.113 47.578 0.95 57.86 O HETATM 901 O HOH A1352 29.435 85.161 40.788 1.12 38.01 O HETATM 902 O HOH A1360 28.741 57.242 47.431 1.10 43.71 O HETATM 903 O HOH A1363 34.140 63.679 52.767 0.79 45.66 O HETATM 904 O HOH A1366 35.925 59.258 65.315 1.07 38.68 O HETATM 905 O HOH A1371 26.973 68.250 53.953 0.94 36.25 O HETATM 906 O HOH A1374 37.205 41.858 49.600 0.98 56.49 O HETATM 907 O HOH A1380 36.882 67.631 56.811 0.89 29.71 O HETATM 908 O HOH A1387 22.770 66.723 39.903 0.97 31.30 O HETATM 909 O HOH A1398 42.435 57.721 57.487 0.76 36.35 O HETATM 910 O HOH A1399 30.413 87.203 47.026 0.99 28.24 O HETATM 911 O HOH A1408 37.027 76.362 39.945 0.74 27.47 O HETATM 912 O HOH A1416 33.190 62.157 39.844 0.98 41.92 O HETATM 913 O HOH A1419 18.786 65.618 51.596 1.11 40.48 O HETATM 914 O HOH A1422 33.438 53.757 47.519 0.99 54.71 O HETATM 915 O HOH A1423 38.218 55.872 60.955 0.88 62.58 O HETATM 916 O HOH A1426 23.824 56.332 47.507 0.87 40.96 O HETATM 917 O HOH A1427 43.541 43.148 46.950 0.98 33.44 O HETATM 918 O HOH A1429 21.014 50.824 46.357 0.96 30.11 O HETATM 919 O HOH A1431 40.565 71.908 43.686 1.03 37.99 O HETATM 920 O HOH A1433 26.489 56.278 54.517 0.91 29.81 O HETATM 921 O HOH A1434 31.347 38.176 42.610 0.89 29.30 O HETATM 922 O HOH A1438 39.361 82.308 43.726 0.91 35.41 O HETATM 923 O HOH A1444 24.922 73.035 34.118 0.83 25.69 O HETATM 924 O HOH A1447 38.788 69.255 53.180 1.09 46.03 O HETATM 925 O HOH A1451 41.257 40.476 42.628 0.90 34.74 O HETATM 926 O HOH A1455 36.596 57.223 62.640 1.03 47.32 O HETATM 927 O HOH A1459 26.201 82.335 41.330 1.01 45.22 O HETATM 928 O HOH A1460 23.287 80.720 52.114 0.89 29.25 O HETATM 929 O HOH A1463 35.935 64.567 64.886 0.86 42.66 O HETATM 930 O HOH A1465 27.234 64.531 51.314 0.80 34.41 O HETATM 931 O HOH A1466 18.922 57.959 46.094 0.94 33.09 O HETATM 932 O HOH A1471 29.616 72.579 57.868 0.88 39.42 O HETATM 933 O HOH A1492 30.644 75.996 57.069 0.84 48.44 O HETATM 934 O HOH A1502 31.199 79.257 35.588 0.93 37.99 O HETATM 935 O HOH A1503 23.098 82.271 33.207 0.94 50.57 O HETATM 936 O HOH A1508 27.531 77.444 35.883 0.85 37.87 O HETATM 937 O HOH A1511 35.083 92.561 50.989 0.90 24.59 O HETATM 938 O HOH A1520 31.361 68.735 31.724 0.72 22.16 O HETATM 939 O HOH A1526 32.374 90.716 43.472 0.98 36.40 O HETATM 940 O HOH A1527 31.774 45.496 49.541 0.90 42.61 O HETATM 941 O HOH A1528 13.689 77.168 45.221 0.78 28.13 O HETATM 942 O HOH A1533 28.522 53.501 44.173 0.84 32.54 O HETATM 943 O HOH A1539 39.960 72.959 45.989 0.86 27.42 O HETATM 944 O HOH A1543 34.300 78.003 48.863 0.98 43.16 O HETATM 945 O HOH A1544 28.596 65.984 63.225 1.10 47.36 O HETATM 946 O HOH A1581 38.826 69.121 55.858 0.75 32.93 O HETATM 947 O HOH A1586 29.178 51.456 50.981 1.03 46.75 O HETATM 948 O HOH A1590 35.728 77.301 42.459 0.97 37.37 O HETATM 949 O HOH A1596 36.460 63.505 37.546 0.81 38.17 O HETATM 950 O HOH A1621 34.952 44.125 51.863 1.02 38.38 O HETATM 951 O HOH A1623 40.085 57.168 47.360 0.94 49.27 O HETATM 952 O HOH A1624 22.013 48.352 57.986 1.22 57.40 O HETATM 953 O HOH A1633 26.347 68.216 59.017 0.69 28.54 O HETATM 954 O HOH A1642 19.994 53.287 62.787 0.85 31.28 O HETATM 955 O HOH A1643 40.343 91.758 51.432 1.13 42.83 O HETATM 956 O HOH A1644 24.446 68.633 53.006 0.95 35.92 O HETATM 957 O HOH A1646 27.358 59.974 40.116 0.81 36.35 O HETATM 958 O HOH A1658 33.874 70.786 34.071 0.83 37.66 O HETATM 959 O HOH A1659 43.340 42.983 44.234 0.88 42.88 O HETATM 960 O HOH A1662 31.571 55.038 48.560 0.65 44.11 O HETATM 961 O HOH A1664 24.755 70.986 32.781 0.99 41.01 O HETATM 962 O HOH A1671 42.131 69.157 42.615 0.96 39.14 O HETATM 963 O HOH A1672 34.670 43.068 49.564 0.78 51.55 O HETATM 964 O HOH A1673 20.773 67.375 37.661 0.76 53.48 O HETATM 965 O HOH A1676 39.896 84.874 44.309 0.97 37.66 O HETATM 966 O HOH A1683 42.245 81.648 44.322 0.96 48.83 O HETATM 967 O HOH A1687 43.351 61.156 61.438 1.17 45.90 O HETATM 968 O HOH A1699 36.428 75.441 44.558 0.90 44.24 O HETATM 969 O HOH A1700 32.836 76.024 46.894 0.76 36.31 O HETATM 970 O HOH A1701 42.231 60.502 57.409 0.96 38.82 O HETATM 971 O HOH A1704 34.076 38.731 42.432 0.88 45.35 O HETATM 972 O HOH A1705 30.147 61.657 38.915 0.84 44.66 O HETATM 973 O HOH A1706 36.770 73.804 40.504 0.80 43.55 O HETATM 974 O HOH A1710 30.976 54.014 41.565 0.81 35.14 O HETATM 975 O HOH A1713 27.703 65.873 53.412 0.78 54.12 O HETATM 976 O HOH A1714 41.194 70.543 47.760 0.82 41.92 O HETATM 977 O HOH A1729 21.365 45.618 55.382 1.09 42.15 O HETATM 978 O HOH A1742 41.674 58.881 53.169 0.93 47.56 O HETATM 979 O HOH A1746 33.762 68.016 58.464 0.87 46.20 O HETATM 980 O HOH A1756 27.707 50.857 48.974 1.04 45.52 O HETATM 981 O HOH A1757 25.320 58.622 54.937 0.92 43.93 O HETATM 982 O HOH A1764 19.045 80.667 39.838 0.84 47.21 O HETATM 983 O HOH A1767 36.743 67.308 60.142 0.86 40.72 O HETATM 984 O HOH A1771 18.984 71.903 49.743 0.83 42.20 O HETATM 985 O HOH A1775 40.597 69.690 51.553 0.48 55.23 O HETATM 986 O HOH A1776 28.605 47.709 46.354 0.98 45.99 O HETATM 987 O HOH A1779 24.961 63.678 50.297 0.95 52.34 O HETATM 988 O HOH A1794 39.841 61.024 52.789 0.90 31.96 O HETATM 989 O HOH A1799 22.251 78.873 53.454 0.80 49.05 O HETATM 990 O HOH A1803 30.480 83.855 38.858 0.90 49.59 O HETATM 991 O HOH A1809 29.527 48.071 48.973 0.85 50.02 O HETATM 992 O HOH A1814 22.224 81.741 54.632 1.01 41.07 O HETATM 993 O HOH A1817 32.469 52.619 55.093 1.10 45.45 O HETATM 994 O HOH A1821 24.297 85.618 44.826 0.94 41.80 O HETATM 995 O HOH A1824 34.679 53.685 45.522 0.66 47.21 O ENDMDL MASTER 0 0 0 0 0 0 26 6 994 1 0 15 END