HEADER RNA 12-APR-00 XXXX TITLE CRYSTAL STRUCTURE OF A VITAMIN B12 BINDING RNA APTAMER WITH LIGAND AT TITLE 2 2.3 A KEYWDS B12 BINDING RNA, VITAMIN B12, COBALAMIN, RNA EXPDTA X-RAY DIFFRACTION AUTHOR D.SUSSMAN,C.WILSON JRNL AUTH D.SUSSMAN,C.WILSON JRNL TITL A WATER CHANNEL IN THE CORE OF THE VITAMIN B(12) RNA JRNL TITL 2 APTAMER. JRNL REF STRUCTURE FOLD.DES. V. 8 719 2000 JRNL REFN ISSN 0969-2126 JRNL PMID 10903943 JRNL DOI 10.1016/S0969-2126(00)00159-3 SEQRES 1 A 35 G G A A C C G G U G C G C SEQRES 2 A 35 A U A A C C A C C U C A G SEQRES 3 A 35 U G C G A G C A A SEQRES 1 B 35 G G A A C C G G U G C G C SEQRES 2 B 35 A U A A C C A C C U C A G SEQRES 3 B 35 U G C G A G C A A SEQRES 1 C 35 G G A A C C G G U G C G C SEQRES 2 C 35 A U A A C C A C C U C A G SEQRES 3 C 35 U G C G A G C A A SEQRES 1 D 35 G G A A C C G G U G C G C SEQRES 2 D 35 A U A A C C A C C U C A G SEQRES 3 D 35 U G C G A G C A A SEQRES 1 E 35 G G A A C C G G U G C G C SEQRES 2 E 35 A U A A C C A C C U C A G SEQRES 3 E 35 U G C G A G C A A HETNAM CNC CYANOCOBALAMIN FORMUL 6 CNC 5(C63 H89 CO N14 O14 P 2+) FORMUL 11 HOH *725(H2 O) SITE 1 AC1 22 C A 211 A A 214 A A 216 C A 229 SITE 2 AC1 22 G A 230 A A 231 HOH A1151 HOH A1180 SITE 3 AC1 22 HOH A1246 HOH A1253 HOH A1272 HOH A1387 SITE 4 AC1 22 HOH A1459 HOH A1503 HOH A1508 HOH A1673 SITE 5 AC1 22 HOH A1764 HOH B1490 HOH B1612 A D 516 SITE 6 AC1 22 HOH D1189 HOH D1443 SITE 1 AC2 22 HOH A1290 C B 311 A B 314 A B 316 SITE 2 AC2 22 C B 329 G B 330 HOH B1121 HOH B1137 SITE 3 AC2 22 HOH B1266 HOH B1293 HOH B1364 HOH B1420 SITE 4 AC2 22 HOH B1468 HOH B1612 HOH B1707 HOH B1709 SITE 5 AC2 22 HOH B1725 HOH B1777 HOH B1802 CNC D1001 SITE 6 AC2 22 HOH D1256 HOH D1328 SITE 1 AC3 15 C C 411 A C 414 A C 416 C C 429 SITE 2 AC3 15 G C 430 HOH C1109 HOH C1139 HOH C1178 SITE 3 AC3 15 HOH C1211 HOH C1236 HOH C1258 HOH C1271 SITE 4 AC3 15 HOH C1454 A E 117 HOH E1314 SITE 1 AC4 21 A A 216 A A 217 HOH A1246 CNC B 801 SITE 2 AC4 21 HOH B1725 C D 511 A D 514 A D 516 SITE 3 AC4 21 C D 529 G D 530 HOH D1107 HOH D1143 SITE 4 AC4 21 HOH D1168 HOH D1232 HOH D1255 HOH D1256 SITE 5 AC4 21 HOH D1288 HOH D1328 HOH D1332 HOH D1409 SITE 6 AC4 21 HOH D1591 SITE 1 AC5 13 A C 417 HOH C1211 C E 111 A E 114 SITE 2 AC5 13 A E 116 C E 129 G E 130 HOH E1281 SITE 3 AC5 13 HOH E1321 HOH E1585 HOH E1754 HOH E1759 SITE 4 AC5 13 HOH E1778 CRYST1 91.270 98.080 217.970 90.00 90.00 90.00 I 2 2 2 40 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.010957 0.000000 0.000000 0.00000 SCALE2 0.000000 0.010196 0.000000 0.00000 SCALE3 0.000000 0.000000 0.004588 0.00000 MODEL 1 ATOM 1 OP3 G B 301 52.800 44.125 59.073 1.00 45.64 O ATOM 2 P G B 301 53.708 45.376 59.244 1.00 46.03 P ATOM 3 OP1 G B 301 54.430 45.823 57.978 1.00 45.29 O ATOM 4 OP2 G B 301 52.940 46.502 59.930 1.00 45.84 O ATOM 5 O5' G B 301 54.910 45.002 60.282 1.00 45.28 O ATOM 6 C5' G B 301 54.615 44.534 61.611 1.00 44.89 C ATOM 7 C4' G B 301 55.895 44.217 62.350 1.00 44.84 C ATOM 8 O4' G B 301 56.628 43.148 61.686 1.00 44.51 O ATOM 9 C3' G B 301 56.900 45.353 62.416 1.00 44.91 C ATOM 10 O3' G B 301 56.542 46.303 63.416 1.00 45.72 O ATOM 11 C2' G B 301 58.191 44.601 62.717 1.00 44.56 C ATOM 12 O2' G B 301 58.242 44.163 64.062 1.00 44.28 O ATOM 13 C1' G B 301 58.029 43.377 61.812 1.00 44.00 C ATOM 14 N9 G B 301 58.577 43.628 60.483 1.00 43.45 N ATOM 15 C8 G B 301 57.901 43.644 59.282 1.00 43.27 C ATOM 16 N7 G B 301 58.663 43.952 58.265 1.00 42.94 N ATOM 17 C5 G B 301 59.922 44.138 58.826 1.00 42.82 C ATOM 18 C6 G B 301 61.159 44.507 58.217 1.00 42.69 C ATOM 19 O6 G B 301 61.394 44.757 57.019 1.00 42.43 O ATOM 20 N1 G B 301 62.184 44.588 59.152 1.00 42.63 N ATOM 21 C2 G B 301 62.047 44.361 60.507 1.00 43.06 C ATOM 22 N2 G B 301 63.170 44.499 61.248 1.00 42.79 N ATOM 23 N3 G B 301 60.895 44.025 61.093 1.00 43.06 N ATOM 24 C4 G B 301 59.885 43.932 60.195 1.00 43.21 C ATOM 25 P G B 302 56.930 47.865 63.223 1.00 46.57 P ATOM 26 OP1 G B 302 56.597 48.480 64.535 1.00 46.56 O ATOM 27 OP2 G B 302 56.348 48.432 61.969 1.00 45.98 O ATOM 28 O5' G B 302 58.517 47.846 63.082 1.00 46.22 O ATOM 29 C5' G B 302 59.325 47.382 64.155 1.00 46.32 C ATOM 30 C4' G B 302 60.768 47.723 63.897 1.00 46.71 C ATOM 31 O4' G B 302 61.300 46.899 62.828 1.00 46.17 O ATOM 32 C3' G B 302 61.022 49.143 63.417 1.00 47.24 C ATOM 33 O3' G B 302 60.987 50.069 64.494 1.00 48.70 O ATOM 34 C2' G B 302 62.396 49.016 62.770 1.00 46.76 C ATOM 35 O2' G B 302 63.426 48.957 63.751 1.00 47.01 O ATOM 36 C1' G B 302 62.262 47.647 62.092 1.00 45.75 C ATOM 37 N9 G B 302 61.786 47.723 60.719 1.00 44.44 N ATOM 38 C8 G B 302 60.506 47.484 60.279 1.00 43.98 C ATOM 39 N7 G B 302 60.389 47.576 58.980 1.00 43.56 N ATOM 40 C5 G B 302 61.662 47.909 58.542 1.00 43.25 C ATOM 41 C6 G B 302 62.150 48.130 57.239 1.00 42.99 C ATOM 42 O6 G B 302 61.542 48.074 56.169 1.00 43.12 O ATOM 43 N1 G B 302 63.499 48.438 57.245 1.00 42.76 N ATOM 44 C2 G B 302 64.281 48.521 58.360 1.00 42.70 C ATOM 45 N2 G B 302 65.557 48.826 58.148 1.00 42.46 N ATOM 46 N3 G B 302 63.843 48.317 59.587 1.00 43.13 N ATOM 47 C4 G B 302 62.533 48.016 59.604 1.00 43.74 C ATOM 48 P A B 303 61.004 51.647 64.185 1.00 50.13 P ATOM 49 OP1 A B 303 60.303 52.330 65.313 1.00 49.67 O ATOM 50 OP2 A B 303 60.551 51.890 62.776 1.00 49.59 O ATOM 51 O5' A B 303 62.560 51.991 64.249 1.00 49.83 O ATOM 52 C5' A B 303 63.025 53.144 63.599 1.00 50.19 C ATOM 53 C4' A B 303 64.351 52.900 62.945 1.00 50.11 C ATOM 54 O4' A B 303 64.351 51.651 62.211 1.00 50.19 O ATOM 55 C3' A B 303 64.676 53.944 61.894 1.00 50.29 C ATOM 56 O3' A B 303 65.148 55.134 62.488 1.00 50.55 O ATOM 57 C2' A B 303 65.697 53.226 61.037 1.00 50.44 C ATOM 58 O2' A B 303 66.975 53.202 61.645 1.00 50.59 O ATOM 59 C1' A B 303 65.084 51.820 60.997 1.00 50.26 C ATOM 60 N9 A B 303 64.150 51.712 59.870 1.00 49.93 N ATOM 61 C8 A B 303 62.798 51.450 59.901 1.00 49.89 C ATOM 62 N7 A B 303 62.240 51.408 58.712 1.00 49.93 N ATOM 63 C5 A B 303 63.293 51.662 57.840 1.00 49.73 C ATOM 64 C6 A B 303 63.364 51.733 56.433 1.00 49.76 C ATOM 65 N6 A B 303 62.315 51.553 55.620 1.00 49.94 N ATOM 66 N1 A B 303 64.569 51.997 55.880 1.00 49.71 N ATOM 67 C2 A B 303 65.628 52.175 56.693 1.00 49.57 C ATOM 68 N3 A B 303 65.687 52.129 58.022 1.00 49.51 N ATOM 69 C4 A B 303 64.473 51.860 58.541 1.00 49.67 C ATOM 70 P A B 304 64.096 56.256 62.947 1.00 50.68 P ATOM 71 OP1 A B 304 64.848 57.542 63.016 1.00 50.89 O ATOM 72 OP2 A B 304 63.362 55.755 64.144 1.00 50.54 O ATOM 73 O5' A B 304 63.078 56.393 61.737 1.00 49.66 O ATOM 74 C5' A B 304 63.334 57.347 60.723 1.00 48.43 C ATOM 75 C4' A B 304 64.762 57.210 60.240 1.00 47.41 C ATOM 76 O4' A B 304 65.052 55.834 59.867 1.00 47.39 O ATOM 77 C3' A B 304 65.101 58.053 59.019 1.00 46.97 C ATOM 78 O3' A B 304 65.614 59.308 59.462 1.00 45.64 O ATOM 79 C2' A B 304 66.095 57.169 58.264 1.00 46.92 C ATOM 80 O2' A B 304 67.380 57.167 58.869 1.00 47.09 O ATOM 81 C1' A B 304 65.494 55.789 58.520 1.00 46.69 C ATOM 82 N9 A B 304 64.326 55.433 57.719 1.00 46.11 N ATOM 83 C8 A B 304 63.088 55.144 58.254 1.00 45.86 C ATOM 84 N7 A B 304 62.197 54.786 57.368 1.00 45.76 N ATOM 85 C5 A B 304 62.882 54.852 56.164 1.00 45.43 C ATOM 86 C6 A B 304 62.481 54.582 54.861 1.00 45.17 C ATOM 87 N6 A B 304 61.243 54.170 54.560 1.00 45.03 N ATOM 88 N1 A B 304 63.392 54.747 53.870 1.00 44.85 N ATOM 89 C2 A B 304 64.630 55.155 54.198 1.00 44.94 C ATOM 90 N3 A B 304 65.133 55.437 55.403 1.00 45.20 N ATOM 91 C4 A B 304 64.195 55.264 56.358 1.00 45.63 C ATOM 92 P C B 305 65.119 60.663 58.755 1.00 44.96 P ATOM 93 OP1 C B 305 66.033 61.740 59.273 1.00 44.74 O ATOM 94 OP2 C B 305 63.624 60.824 58.903 1.00 44.30 O ATOM 95 O5' C B 305 65.480 60.377 57.227 1.00 42.89 O ATOM 96 C5' C B 305 64.810 61.039 56.174 1.00 40.05 C ATOM 97 C4' C B 305 65.385 60.589 54.854 1.00 38.41 C ATOM 98 O4' C B 305 65.192 59.155 54.691 1.00 37.74 O ATOM 99 C3' C B 305 64.732 61.198 53.625 1.00 37.43 C ATOM 100 O3' C B 305 65.267 62.494 53.370 1.00 36.66 O ATOM 101 C2' C B 305 65.084 60.187 52.546 1.00 37.05 C ATOM 102 O2' C B 305 66.425 60.337 52.147 1.00 36.72 O ATOM 103 C1' C B 305 64.939 58.869 53.319 1.00 37.00 C ATOM 104 N1 C B 305 63.587 58.285 53.205 1.00 36.17 N ATOM 105 C2 C B 305 63.149 57.826 51.954 1.00 35.55 C ATOM 106 O2 C B 305 63.900 57.921 50.987 1.00 35.46 O ATOM 107 N3 C B 305 61.924 57.291 51.835 1.00 34.93 N ATOM 108 C4 C B 305 61.133 57.197 52.898 1.00 35.13 C ATOM 109 N4 C B 305 59.930 56.659 52.725 1.00 34.69 N ATOM 110 C5 C B 305 61.541 57.655 54.191 1.00 35.28 C ATOM 111 C6 C B 305 62.768 58.189 54.298 1.00 35.86 C ATOM 112 P C B 306 64.351 63.614 52.655 1.00 35.92 P ATOM 113 OP1 C B 306 65.115 64.877 52.499 1.00 35.99 O ATOM 114 OP2 C B 306 63.033 63.622 53.355 1.00 35.60 O ATOM 115 O5' C B 306 64.198 63.080 51.171 1.00 34.65 O ATOM 116 C5' C B 306 65.310 63.082 50.304 1.00 32.92 C ATOM 117 C4' C B 306 64.880 62.629 48.946 1.00 32.25 C ATOM 118 O4' C B 306 64.396 61.260 49.015 1.00 31.95 O ATOM 119 C3' C B 306 63.704 63.383 48.365 1.00 32.09 C ATOM 120 O3' C B 306 64.159 64.616 47.835 1.00 31.99 O ATOM 121 C2' C B 306 63.210 62.397 47.312 1.00 31.90 C ATOM 122 O2' C B 306 64.103 62.326 46.219 1.00 32.03 O ATOM 123 C1' C B 306 63.353 61.074 48.062 1.00 31.39 C ATOM 124 N1 C B 306 62.146 60.648 48.793 1.00 30.61 N ATOM 125 C2 C B 306 61.049 60.144 48.087 1.00 30.13 C ATOM 126 O2 C B 306 61.098 60.103 46.842 1.00 29.78 O ATOM 127 N3 C B 306 59.962 59.717 48.778 1.00 29.62 N ATOM 128 C4 C B 306 59.948 59.792 50.112 1.00 29.73 C ATOM 129 N4 C B 306 58.868 59.350 50.774 1.00 29.48 N ATOM 130 C5 C B 306 61.044 60.318 50.844 1.00 29.83 C ATOM 131 C6 C B 306 62.109 60.731 50.154 1.00 30.30 C ATOM 132 P G B 307 63.125 65.833 47.627 1.00 32.24 P ATOM 133 OP1 G B 307 63.933 66.951 47.055 1.00 31.79 O ATOM 134 OP2 G B 307 62.357 66.034 48.891 1.00 31.52 O ATOM 135 O5' G B 307 62.112 65.293 46.514 1.00 31.12 O ATOM 136 C5' G B 307 62.470 65.226 45.139 1.00 29.13 C ATOM 137 C4' G B 307 61.270 64.789 44.319 1.00 28.23 C ATOM 138 O4' G B 307 60.871 63.428 44.655 1.00 28.03 O ATOM 139 C3' G B 307 60.001 65.587 44.546 1.00 27.67 C ATOM 140 O3' G B 307 60.038 66.799 43.815 1.00 27.08 O ATOM 141 C2' G B 307 58.937 64.636 44.020 1.00 27.63 C ATOM 142 O2' G B 307 58.963 64.612 42.605 1.00 27.93 O ATOM 143 C1' G B 307 59.457 63.289 44.536 1.00 27.21 C ATOM 144 N9 G B 307 58.931 62.925 45.854 1.00 26.79 N ATOM 145 C8 G B 307 59.582 63.078 47.051 1.00 26.00 C ATOM 146 N7 G B 307 58.872 62.683 48.072 1.00 25.92 N ATOM 147 C5 G B 307 57.678 62.227 47.519 1.00 25.59 C ATOM 148 C6 G B 307 56.532 61.669 48.139 1.00 25.47 C ATOM 149 O6 G B 307 56.335 61.438 49.328 1.00 25.71 O ATOM 150 N1 G B 307 55.549 61.357 47.220 1.00 25.49 N ATOM 151 C2 G B 307 55.645 61.551 45.873 1.00 25.58 C ATOM 152 N2 G B 307 54.569 61.190 45.153 1.00 25.39 N ATOM 153 N3 G B 307 56.709 62.059 45.278 1.00 25.88 N ATOM 154 C4 G B 307 57.687 62.370 46.159 1.00 25.96 C ATOM 155 P G B 308 59.261 68.086 44.376 1.00 26.87 P ATOM 156 OP1 G B 308 59.470 69.200 43.418 1.00 27.19 O ATOM 157 OP2 G B 308 59.572 68.276 45.823 1.00 27.00 O ATOM 158 O5' G B 308 57.725 67.675 44.263 1.00 26.38 O ATOM 159 C5' G B 308 57.150 67.377 42.996 1.00 24.91 C ATOM 160 C4' G B 308 55.779 66.777 43.181 1.00 24.10 C ATOM 161 O4' G B 308 55.900 65.519 43.898 1.00 23.50 O ATOM 162 C3' G B 308 54.823 67.573 44.048 1.00 23.59 C ATOM 163 O3' G B 308 54.202 68.634 43.341 1.00 23.83 O ATOM 164 C2' G B 308 53.818 66.511 44.442 1.00 22.88 C ATOM 165 O2' G B 308 53.033 66.248 43.301 1.00 22.27 O ATOM 166 C1' G B 308 54.746 65.321 44.705 1.00 22.39 C ATOM 167 N9 G B 308 55.180 65.205 46.099 1.00 21.81 N ATOM 168 C8 G B 308 56.400 65.566 46.630 1.00 21.24 C ATOM 169 N7 G B 308 56.497 65.310 47.919 1.00 20.82 N ATOM 170 C5 G B 308 55.273 64.744 48.252 1.00 20.45 C ATOM 171 C6 G B 308 54.813 64.256 49.473 1.00 20.49 C ATOM 172 O6 G B 308 55.425 64.189 50.560 1.00 20.73 O ATOM 173 N1 G B 308 53.496 63.791 49.377 1.00 20.53 N ATOM 174 C2 G B 308 52.736 63.787 48.223 1.00 20.22 C ATOM 175 N2 G B 308 51.465 63.300 48.307 1.00 19.14 N ATOM 176 N3 G B 308 53.179 64.226 47.070 1.00 20.20 N ATOM 177 C4 G B 308 54.442 64.687 47.153 1.00 20.87 C ATOM 178 P U B 309 53.797 69.972 44.146 1.00 23.59 P ATOM 179 OP1 U B 309 53.399 71.008 43.161 1.00 23.56 O ATOM 180 OP2 U B 309 54.890 70.251 45.121 1.00 23.18 O ATOM 181 O5' U B 309 52.499 69.548 44.966 1.00 23.03 O ATOM 182 C5' U B 309 51.253 69.331 44.301 1.00 22.63 C ATOM 183 C4' U B 309 50.203 68.845 45.286 1.00 22.27 C ATOM 184 O4' U B 309 50.596 67.580 45.883 1.00 21.88 O ATOM 185 C3' U B 309 49.968 69.742 46.487 1.00 22.09 C ATOM 186 O3' U B 309 49.121 70.811 46.126 1.00 22.28 O ATOM 187 C2' U B 309 49.294 68.790 47.461 1.00 21.67 C ATOM 188 O2' U B 309 47.954 68.549 47.084 1.00 21.30 O ATOM 189 C1' U B 309 50.093 67.513 47.217 1.00 21.40 C ATOM 190 N1 U B 309 51.230 67.414 48.141 1.00 21.03 N ATOM 191 C2 U B 309 50.984 66.949 49.402 1.00 20.93 C ATOM 192 O2 U B 309 49.863 66.625 49.774 1.00 21.23 O ATOM 193 N3 U B 309 52.082 66.878 50.227 1.00 20.69 N ATOM 194 C4 U B 309 53.369 67.224 49.923 1.00 20.59 C ATOM 195 O4 U B 309 54.251 67.093 50.781 1.00 21.00 O ATOM 196 C5 U B 309 53.552 67.706 48.593 1.00 20.94 C ATOM 197 C6 U B 309 52.501 67.782 47.765 1.00 21.06 C ATOM 198 P G B 310 49.402 72.268 46.722 1.00 22.64 P ATOM 199 OP1 G B 310 48.578 73.249 45.937 1.00 22.14 O ATOM 200 OP2 G B 310 50.869 72.431 46.781 1.00 22.15 O ATOM 201 O5' G B 310 48.877 72.148 48.229 1.00 21.68 O ATOM 202 C5' G B 310 47.499 71.932 48.509 1.00 20.71 C ATOM 203 C4' G B 310 47.105 72.599 49.809 1.00 20.05 C ATOM 204 O4' G B 310 47.747 71.967 50.947 1.00 19.47 O ATOM 205 C3' G B 310 47.538 74.045 49.962 1.00 20.17 C ATOM 206 O3' G B 310 46.659 74.888 49.244 1.00 21.63 O ATOM 207 C2' G B 310 47.367 74.268 51.464 1.00 19.32 C ATOM 208 O2' G B 310 46.026 74.523 51.812 1.00 18.79 O ATOM 209 C1' G B 310 47.735 72.894 52.031 1.00 18.50 C ATOM 210 N9 G B 310 49.016 72.843 52.723 1.00 17.47 N ATOM 211 C8 G B 310 50.250 73.189 52.230 1.00 16.76 C ATOM 212 N7 G B 310 51.213 73.013 53.098 1.00 16.73 N ATOM 213 C5 G B 310 50.568 72.529 54.231 1.00 16.43 C ATOM 214 C6 G B 310 51.089 72.146 55.479 1.00 16.38 C ATOM 215 O6 G B 310 52.271 72.158 55.847 1.00 16.19 O ATOM 216 N1 G B 310 50.082 71.698 56.345 1.00 16.32 N ATOM 217 C2 G B 310 48.736 71.637 56.026 1.00 16.57 C ATOM 218 N2 G B 310 47.881 71.182 56.986 1.00 15.57 N ATOM 219 N3 G B 310 48.255 71.995 54.849 1.00 16.30 N ATOM 220 C4 G B 310 49.215 72.419 54.012 1.00 16.50 C ATOM 221 P C B 311 47.215 76.235 48.579 1.00 23.39 P ATOM 222 OP1 C B 311 46.007 77.064 48.231 1.00 23.29 O ATOM 223 OP2 C B 311 48.204 75.887 47.534 1.00 22.76 O ATOM 224 O5' C B 311 47.989 76.974 49.778 1.00 23.52 O ATOM 225 C5' C B 311 47.827 78.392 49.997 1.00 23.12 C ATOM 226 C4' C B 311 47.025 78.669 51.268 1.00 23.53 C ATOM 227 O4' C B 311 47.737 78.190 52.439 1.00 23.05 O ATOM 228 C3' C B 311 46.822 80.148 51.578 1.00 23.98 C ATOM 229 O3' C B 311 45.668 80.640 50.887 1.00 25.52 O ATOM 230 C2' C B 311 46.550 80.152 53.095 1.00 23.36 C ATOM 231 O2' C B 311 45.179 80.029 53.345 1.00 23.85 O ATOM 232 C1' C B 311 47.223 78.853 53.581 1.00 22.58 C ATOM 233 N1 C B 311 48.282 78.941 54.607 1.00 21.06 N ATOM 234 C2 C B 311 48.074 78.315 55.847 1.00 20.49 C ATOM 235 O2 C B 311 46.977 77.784 56.087 1.00 20.09 O ATOM 236 N3 C B 311 49.072 78.304 56.759 1.00 20.07 N ATOM 237 C4 C B 311 50.234 78.894 56.482 1.00 20.00 C ATOM 238 N4 C B 311 51.206 78.811 57.409 1.00 19.75 N ATOM 239 C5 C B 311 50.458 79.582 55.254 1.00 19.59 C ATOM 240 C6 C B 311 49.465 79.581 54.354 1.00 20.46 C ATOM 241 P G B 312 45.787 81.177 49.366 1.00 26.93 P ATOM 242 OP1 G B 312 45.130 80.168 48.508 1.00 27.34 O ATOM 243 OP2 G B 312 47.200 81.561 49.082 1.00 26.89 O ATOM 244 O5' G B 312 44.857 82.494 49.401 1.00 28.33 O ATOM 245 C5' G B 312 44.809 83.438 48.315 1.00 29.56 C ATOM 246 C4' G B 312 44.242 84.782 48.787 1.00 30.45 C ATOM 247 O4' G B 312 42.923 84.575 49.362 1.00 30.54 O ATOM 248 C3' G B 312 45.070 85.484 49.857 1.00 31.03 C ATOM 249 O3' G B 312 46.195 84.774 50.291 1.00 31.92 O ATOM 250 C2' G B 312 44.040 86.112 50.793 1.00 30.88 C ATOM 251 O2' G B 312 43.670 87.401 50.360 1.00 31.22 O ATOM 252 C1' G B 312 42.834 85.193 50.624 1.00 30.57 C ATOM 253 N9 G B 312 42.587 84.157 51.622 1.00 30.44 N ATOM 254 C8 G B 312 42.677 82.800 51.438 1.00 30.36 C ATOM 255 N7 G B 312 42.317 82.115 52.493 1.00 30.32 N ATOM 256 C5 G B 312 41.986 83.077 53.435 1.00 29.86 C ATOM 257 C6 G B 312 41.516 82.930 54.758 1.00 29.96 C ATOM 258 O6 G B 312 41.289 81.884 55.390 1.00 29.92 O ATOM 259 N1 G B 312 41.304 84.162 55.362 1.00 29.93 N ATOM 260 C2 G B 312 41.513 85.378 54.766 1.00 30.14 C ATOM 261 N2 G B 312 41.253 86.449 55.527 1.00 30.26 N ATOM 262 N3 G B 312 41.945 85.533 53.523 1.00 30.10 N ATOM 263 C4 G B 312 42.161 84.344 52.922 1.00 30.27 C ATOM 264 P C B 313 47.552 85.534 50.654 1.00 31.57 P ATOM 265 OP1 C B 313 47.992 86.442 49.588 1.00 32.09 O ATOM 266 OP2 C B 313 48.378 84.340 51.003 1.00 32.18 O ATOM 267 O5' C B 313 47.223 86.302 52.008 1.00 31.57 O ATOM 268 C5' C B 313 46.796 87.651 52.038 1.00 31.27 C ATOM 269 C4' C B 313 46.421 88.030 53.462 1.00 31.10 C ATOM 270 O4' C B 313 45.172 87.403 53.853 1.00 30.65 O ATOM 271 C3' C B 313 47.409 87.602 54.538 1.00 31.37 C ATOM 272 O3' C B 313 48.417 88.583 54.619 1.00 31.88 O ATOM 273 C2' C B 313 46.541 87.626 55.791 1.00 30.98 C ATOM 274 O2' C B 313 46.331 88.948 56.215 1.00 31.22 O ATOM 275 C1' C B 313 45.199 87.119 55.246 1.00 30.67 C ATOM 276 N1 C B 313 45.007 85.673 55.431 1.00 30.11 N ATOM 277 C2 C B 313 44.493 85.214 56.633 1.00 29.98 C ATOM 278 O2 C B 313 44.198 86.026 57.499 1.00 30.37 O ATOM 279 N3 C B 313 44.334 83.885 56.824 1.00 30.08 N ATOM 280 C4 C B 313 44.666 83.029 55.857 1.00 29.61 C ATOM 281 N4 C B 313 44.506 81.735 56.093 1.00 29.38 N ATOM 282 C5 C B 313 45.183 83.473 54.611 1.00 29.63 C ATOM 283 C6 C B 313 45.339 84.790 54.441 1.00 29.90 C ATOM 284 P A B 314 49.970 88.177 54.706 1.00 32.70 P ATOM 285 OP1 A B 314 50.402 88.237 56.131 1.00 33.00 O ATOM 286 OP2 A B 314 50.692 88.971 53.686 1.00 32.82 O ATOM 287 O5' A B 314 50.090 86.639 54.311 1.00 32.65 O ATOM 288 C5' A B 314 51.392 86.032 54.250 1.00 31.50 C ATOM 289 C4' A B 314 51.280 84.530 54.263 1.00 30.94 C ATOM 290 O4' A B 314 50.690 84.117 55.525 1.00 30.85 O ATOM 291 C3' A B 314 50.401 83.921 53.180 1.00 30.56 C ATOM 292 O3' A B 314 50.907 82.617 52.950 1.00 30.07 O ATOM 293 C2' A B 314 49.055 83.796 53.883 1.00 30.70 C ATOM 294 O2' A B 314 48.288 82.751 53.332 1.00 30.56 O ATOM 295 C1' A B 314 49.500 83.403 55.290 1.00 30.43 C ATOM 296 N9 A B 314 48.601 83.714 56.396 1.00 30.55 N ATOM 297 C8 A B 314 48.263 84.952 56.907 1.00 30.72 C ATOM 298 N7 A B 314 47.554 84.891 58.014 1.00 30.38 N ATOM 299 C5 A B 314 47.394 83.528 58.231 1.00 30.44 C ATOM 300 C6 A B 314 46.766 82.789 59.261 1.00 30.51 C ATOM 301 N6 A B 314 46.176 83.330 60.341 1.00 29.86 N ATOM 302 N1 A B 314 46.778 81.441 59.152 1.00 30.59 N ATOM 303 C2 A B 314 47.384 80.884 58.099 1.00 30.67 C ATOM 304 N3 A B 314 48.018 81.466 57.086 1.00 30.56 N ATOM 305 C4 A B 314 47.995 82.797 57.213 1.00 30.56 C ATOM 306 P U B 315 51.077 82.069 51.454 1.00 29.67 P ATOM 307 OP1 U B 315 52.103 82.902 50.771 1.00 30.03 O ATOM 308 OP2 U B 315 49.735 81.912 50.838 1.00 29.58 O ATOM 309 O5' U B 315 51.728 80.631 51.714 1.00 29.78 O ATOM 310 C5' U B 315 53.067 80.524 52.225 1.00 28.72 C ATOM 311 C4' U B 315 53.547 79.079 52.217 1.00 28.05 C ATOM 312 O4' U B 315 53.011 78.356 53.369 1.00 27.60 O ATOM 313 C3' U B 315 53.143 78.259 50.992 1.00 27.96 C ATOM 314 O3' U B 315 54.199 77.366 50.658 1.00 28.09 O ATOM 315 C2' U B 315 52.010 77.394 51.546 1.00 27.55 C ATOM 316 O2' U B 315 51.798 76.192 50.832 1.00 27.75 O ATOM 317 C1' U B 315 52.575 77.086 52.927 1.00 26.95 C ATOM 318 N1 U B 315 51.650 76.507 53.911 1.00 25.76 N ATOM 319 C2 U B 315 52.192 76.054 55.078 1.00 25.27 C ATOM 320 O2 U B 315 53.386 76.131 55.297 1.00 24.82 O ATOM 321 N3 U B 315 51.299 75.513 55.966 1.00 24.89 N ATOM 322 C4 U B 315 49.926 75.388 55.784 1.00 24.93 C ATOM 323 O4 U B 315 49.216 74.859 56.668 1.00 24.64 O ATOM 324 C5 U B 315 49.454 75.892 54.534 1.00 24.81 C ATOM 325 C6 U B 315 50.308 76.419 53.667 1.00 25.17 C ATOM 326 P A B 316 55.614 77.950 50.148 1.00 28.45 P ATOM 327 OP1 A B 316 55.468 79.395 49.850 1.00 28.88 O ATOM 328 OP2 A B 316 56.155 77.042 49.127 1.00 28.27 O ATOM 329 O5' A B 316 56.536 77.837 51.444 1.00 28.30 O ATOM 330 C5' A B 316 56.741 76.581 52.052 1.00 27.61 C ATOM 331 C4' A B 316 58.125 76.513 52.637 1.00 27.31 C ATOM 332 O4' A B 316 58.288 77.549 53.657 1.00 26.83 O ATOM 333 C3' A B 316 58.428 75.219 53.370 1.00 26.92 C ATOM 334 O3' A B 316 58.785 74.202 52.449 1.00 26.79 O ATOM 335 C2' A B 316 59.548 75.643 54.300 1.00 26.48 C ATOM 336 O2' A B 316 60.730 75.828 53.547 1.00 26.58 O ATOM 337 C1' A B 316 59.031 77.017 54.753 1.00 26.26 C ATOM 338 N9 A B 316 58.121 76.891 55.895 1.00 25.33 N ATOM 339 C8 A B 316 56.786 77.198 55.939 1.00 24.78 C ATOM 340 N7 A B 316 56.214 76.915 57.087 1.00 24.56 N ATOM 341 C5 A B 316 57.250 76.400 57.854 1.00 24.72 C ATOM 342 C6 A B 316 57.297 75.914 59.176 1.00 24.68 C ATOM 343 N6 A B 316 56.235 75.867 59.980 1.00 24.67 N ATOM 344 N1 A B 316 58.488 75.474 59.647 1.00 24.73 N ATOM 345 C2 A B 316 59.552 75.532 58.832 1.00 24.79 C ATOM 346 N3 A B 316 59.631 75.969 57.568 1.00 24.89 N ATOM 347 C4 A B 316 58.432 76.394 57.138 1.00 24.80 C ATOM 348 P A B 317 58.380 72.682 52.761 1.00 26.46 P ATOM 349 OP1 A B 317 58.803 71.861 51.595 1.00 26.65 O ATOM 350 OP2 A B 317 56.953 72.659 53.211 1.00 26.88 O ATOM 351 O5' A B 317 59.249 72.290 54.041 1.00 26.55 O ATOM 352 C5' A B 317 60.679 72.283 54.016 1.00 26.23 C ATOM 353 C4' A B 317 61.188 71.954 55.398 1.00 26.17 C ATOM 354 O4' A B 317 60.667 72.954 56.314 1.00 26.20 O ATOM 355 C3' A B 317 60.655 70.657 55.977 1.00 26.37 C ATOM 356 O3' A B 317 61.402 69.529 55.550 1.00 27.45 O ATOM 357 C2' A B 317 60.772 70.892 57.471 1.00 25.96 C ATOM 358 O2' A B 317 62.105 70.791 57.902 1.00 26.36 O ATOM 359 C1' A B 317 60.376 72.360 57.568 1.00 25.67 C ATOM 360 N9 A B 317 58.962 72.573 57.857 1.00 25.03 N ATOM 361 C8 A B 317 58.009 73.069 57.007 1.00 24.96 C ATOM 362 N7 A B 317 56.815 73.145 57.537 1.00 24.67 N ATOM 363 C5 A B 317 56.992 72.663 58.827 1.00 24.05 C ATOM 364 C6 A B 317 56.105 72.496 59.885 1.00 23.77 C ATOM 365 N6 A B 317 54.810 72.798 59.814 1.00 22.70 N ATOM 366 N1 A B 317 56.597 72.008 61.043 1.00 23.95 N ATOM 367 C2 A B 317 57.918 71.713 61.116 1.00 23.82 C ATOM 368 N3 A B 317 58.850 71.828 60.183 1.00 24.14 N ATOM 369 C4 A B 317 58.313 72.314 59.044 1.00 24.49 C ATOM 370 P C B 318 60.647 68.128 55.362 1.00 28.01 P ATOM 371 OP1 C B 318 61.673 67.095 55.046 1.00 28.30 O ATOM 372 OP2 C B 318 59.509 68.359 54.419 1.00 27.84 O ATOM 373 O5' C B 318 60.089 67.843 56.825 1.00 27.77 O ATOM 374 C5' C B 318 60.985 67.449 57.864 1.00 27.44 C ATOM 375 C4' C B 318 60.256 67.329 59.184 1.00 27.19 C ATOM 376 O4' C B 318 59.579 68.577 59.473 1.00 27.01 O ATOM 377 C3' C B 318 59.155 66.286 59.248 1.00 27.15 C ATOM 378 O3' C B 318 59.693 65.015 59.543 1.00 27.18 O ATOM 379 C2' C B 318 58.311 66.798 60.403 1.00 27.18 C ATOM 380 O2' C B 318 58.950 66.557 61.647 1.00 27.26 O ATOM 381 C1' C B 318 58.357 68.303 60.143 1.00 26.82 C ATOM 382 N1 C B 318 57.258 68.807 59.300 1.00 26.52 N ATOM 383 C2 C B 318 55.979 68.914 59.841 1.00 26.31 C ATOM 384 O2 C B 318 55.787 68.527 61.021 1.00 26.73 O ATOM 385 N3 C B 318 54.975 69.431 59.077 1.00 25.52 N ATOM 386 C4 C B 318 55.220 69.817 57.829 1.00 25.69 C ATOM 387 N4 C B 318 54.201 70.325 57.113 1.00 25.56 N ATOM 388 C5 C B 318 56.513 69.705 57.250 1.00 25.67 C ATOM 389 C6 C B 318 57.492 69.193 58.009 1.00 26.31 C ATOM 390 P C B 319 59.181 63.718 58.740 1.00 27.13 P ATOM 391 OP1 C B 319 59.983 62.552 59.169 1.00 27.15 O ATOM 392 OP2 C B 319 59.111 64.084 57.307 1.00 26.93 O ATOM 393 O5' C B 319 57.701 63.489 59.289 1.00 27.02 O ATOM 394 C5' C B 319 57.452 63.280 60.676 1.00 25.78 C ATOM 395 C4' C B 319 55.992 63.552 60.970 1.00 25.40 C ATOM 396 O4' C B 319 55.710 64.950 60.684 1.00 25.20 O ATOM 397 C3' C B 319 54.993 62.816 60.092 1.00 25.24 C ATOM 398 O3' C B 319 54.747 61.488 60.526 1.00 25.25 O ATOM 399 C2' C B 319 53.754 63.691 60.217 1.00 24.91 C ATOM 400 O2' C B 319 53.150 63.527 61.479 1.00 24.96 O ATOM 401 C1' C B 319 54.377 65.083 60.199 1.00 24.46 C ATOM 402 N1 C B 319 54.417 65.722 58.872 1.00 23.31 N ATOM 403 C2 C B 319 53.284 66.389 58.406 1.00 22.67 C ATOM 404 O2 C B 319 52.258 66.411 59.124 1.00 21.32 O ATOM 405 N3 C B 319 53.335 67.003 57.186 1.00 22.58 N ATOM 406 C4 C B 319 54.458 66.957 56.464 1.00 22.44 C ATOM 407 N4 C B 319 54.481 67.580 55.296 1.00 21.84 N ATOM 408 C5 C B 319 55.613 66.273 56.918 1.00 22.60 C ATOM 409 C6 C B 319 55.551 65.678 58.116 1.00 23.09 C ATOM 410 P A B 320 54.330 60.381 59.437 1.00 25.21 P ATOM 411 OP1 A B 320 54.029 59.103 60.133 1.00 25.87 O ATOM 412 OP2 A B 320 55.336 60.392 58.361 1.00 25.49 O ATOM 413 O5' A B 320 52.948 60.946 58.865 1.00 25.37 O ATOM 414 C5' A B 320 51.772 60.889 59.669 1.00 24.69 C ATOM 415 C4' A B 320 50.601 61.553 58.972 1.00 24.81 C ATOM 416 O4' A B 320 50.904 62.949 58.665 1.00 24.43 O ATOM 417 C3' A B 320 50.199 60.975 57.625 1.00 24.74 C ATOM 418 O3' A B 320 49.382 59.825 57.751 1.00 25.29 O ATOM 419 C2' A B 320 49.407 62.124 57.027 1.00 24.05 C ATOM 420 O2' A B 320 48.177 62.253 57.709 1.00 24.18 O ATOM 421 C1' A B 320 50.266 63.316 57.439 1.00 23.59 C ATOM 422 N9 A B 320 51.310 63.651 56.462 1.00 22.54 N ATOM 423 C8 A B 320 52.643 63.335 56.567 1.00 21.84 C ATOM 424 N7 A B 320 53.378 63.809 55.576 1.00 21.99 N ATOM 425 C5 A B 320 52.465 64.464 54.756 1.00 21.15 C ATOM 426 C6 A B 320 52.616 65.168 53.541 1.00 20.76 C ATOM 427 N6 A B 320 53.787 65.334 52.912 1.00 20.09 N ATOM 428 N1 A B 320 51.507 65.702 52.980 1.00 20.15 N ATOM 429 C2 A B 320 50.334 65.527 53.603 1.00 20.31 C ATOM 430 N3 A B 320 50.064 64.885 54.741 1.00 20.83 N ATOM 431 C4 A B 320 51.184 64.368 55.279 1.00 21.67 C ATOM 432 P C B 321 49.468 58.660 56.636 1.00 26.82 P ATOM 433 OP1 C B 321 48.428 57.673 57.030 1.00 25.88 O ATOM 434 OP2 C B 321 50.892 58.224 56.435 1.00 26.19 O ATOM 435 O5' C B 321 49.035 59.349 55.260 1.00 25.97 O ATOM 436 C5' C B 321 47.676 59.686 55.039 1.00 25.30 C ATOM 437 C4' C B 321 47.534 60.525 53.800 1.00 24.94 C ATOM 438 O4' C B 321 48.395 61.684 53.893 1.00 24.45 O ATOM 439 C3' C B 321 47.939 59.877 52.488 1.00 24.69 C ATOM 440 O3' C B 321 46.878 59.058 52.014 1.00 25.32 O ATOM 441 C2' C B 321 48.160 61.100 51.605 1.00 24.19 C ATOM 442 O2' C B 321 46.934 61.715 51.276 1.00 24.22 O ATOM 443 C1' C B 321 48.834 62.055 52.589 1.00 23.93 C ATOM 444 N1 C B 321 50.300 61.999 52.565 1.00 23.26 N ATOM 445 C2 C B 321 50.981 62.696 51.564 1.00 22.76 C ATOM 446 O2 C B 321 50.330 63.331 50.735 1.00 22.53 O ATOM 447 N3 C B 321 52.333 62.661 51.531 1.00 22.38 N ATOM 448 C4 C B 321 53.001 61.964 52.454 1.00 22.23 C ATOM 449 N4 C B 321 54.326 61.970 52.389 1.00 22.19 N ATOM 450 C5 C B 321 52.332 61.234 53.486 1.00 22.18 C ATOM 451 C6 C B 321 50.992 61.280 53.504 1.00 22.65 C ATOM 452 P C B 322 47.178 57.835 50.994 1.00 25.90 P ATOM 453 OP1 C B 322 45.848 57.182 50.763 1.00 26.52 O ATOM 454 OP2 C B 322 48.335 57.003 51.431 1.00 25.43 O ATOM 455 O5' C B 322 47.611 58.558 49.645 1.00 25.88 O ATOM 456 C5' C B 322 46.717 59.422 48.962 1.00 26.12 C ATOM 457 C4' C B 322 47.342 59.898 47.670 1.00 26.58 C ATOM 458 O4' C B 322 48.638 60.509 47.964 1.00 26.27 O ATOM 459 C3' C B 322 47.612 58.838 46.603 1.00 26.70 C ATOM 460 O3' C B 322 47.551 59.536 45.360 1.00 27.88 O ATOM 461 C2' C B 322 49.086 58.495 46.844 1.00 26.82 C ATOM 462 O2' C B 322 49.714 58.043 45.641 1.00 27.31 O ATOM 463 C1' C B 322 49.656 59.878 47.213 1.00 26.03 C ATOM 464 N1 C B 322 50.875 59.859 48.038 1.00 24.64 N ATOM 465 C2 C B 322 52.093 60.309 47.505 1.00 24.19 C ATOM 466 O2 C B 322 52.129 60.697 46.336 1.00 23.78 O ATOM 467 N3 C B 322 53.206 60.300 48.285 1.00 23.77 N ATOM 468 C4 C B 322 53.128 59.858 49.544 1.00 23.84 C ATOM 469 N4 C B 322 54.238 59.852 50.294 1.00 23.95 N ATOM 470 C5 C B 322 51.904 59.394 50.104 1.00 24.04 C ATOM 471 C6 C B 322 50.815 59.411 49.322 1.00 24.51 C ATOM 472 P U B 323 46.607 59.029 44.150 1.00 28.24 P ATOM 473 OP1 U B 323 45.567 58.098 44.654 1.00 28.35 O ATOM 474 OP2 U B 323 47.553 58.589 43.097 1.00 28.15 O ATOM 475 O5' U B 323 45.909 60.396 43.675 1.00 28.36 O ATOM 476 C5' U B 323 45.134 61.182 44.598 1.00 27.67 C ATOM 477 C4' U B 323 44.779 62.526 43.996 1.00 27.34 C ATOM 478 O4' U B 323 46.014 63.209 43.690 1.00 26.98 O ATOM 479 C3' U B 323 44.035 62.492 42.664 1.00 27.34 C ATOM 480 O3' U B 323 42.678 62.152 42.511 1.00 27.49 O ATOM 481 C2' U B 323 45.135 62.466 41.641 1.00 27.17 C ATOM 482 O2' U B 323 44.703 62.878 40.368 1.00 27.90 O ATOM 483 C1' U B 323 46.056 63.488 42.304 1.00 26.93 C ATOM 484 N1 U B 323 47.447 63.462 41.867 1.00 26.34 N ATOM 485 C2 U B 323 47.801 64.411 40.971 1.00 26.17 C ATOM 486 O2 U B 323 46.986 65.227 40.544 1.00 26.55 O ATOM 487 N3 U B 323 49.118 64.390 40.587 1.00 25.93 N ATOM 488 C4 U B 323 50.073 63.520 41.012 1.00 25.95 C ATOM 489 O4 U B 323 51.230 63.649 40.601 1.00 26.91 O ATOM 490 C5 U B 323 49.616 62.537 41.952 1.00 26.14 C ATOM 491 C6 U B 323 48.344 62.545 42.338 1.00 25.98 C ATOM 492 P C B 324 41.682 63.043 41.625 1.00 27.08 P ATOM 493 OP1 C B 324 40.810 61.935 41.134 1.00 28.63 O ATOM 494 OP2 C B 324 42.291 63.966 40.641 1.00 27.76 O ATOM 495 O5' C B 324 40.793 63.849 42.671 1.00 26.82 O ATOM 496 C5' C B 324 40.997 65.233 42.926 1.00 25.38 C ATOM 497 C4' C B 324 40.522 65.558 44.320 1.00 24.84 C ATOM 498 O4' C B 324 39.075 65.413 44.350 1.00 24.22 O ATOM 499 C3' C B 324 41.060 64.639 45.414 1.00 24.33 C ATOM 500 O3' C B 324 41.175 65.364 46.636 1.00 24.26 O ATOM 501 C2' C B 324 39.935 63.611 45.552 1.00 24.27 C ATOM 502 O2' C B 324 39.850 62.999 46.818 1.00 23.62 O ATOM 503 C1' C B 324 38.707 64.487 45.343 1.00 24.28 C ATOM 504 N1 C B 324 37.496 63.773 44.893 1.00 24.76 N ATOM 505 C2 C B 324 36.313 63.950 45.603 1.00 24.65 C ATOM 506 O2 C B 324 36.314 64.694 46.583 1.00 25.02 O ATOM 507 N3 C B 324 35.197 63.304 45.210 1.00 24.78 N ATOM 508 C4 C B 324 35.231 62.491 44.151 1.00 24.79 C ATOM 509 N4 C B 324 34.093 61.853 43.802 1.00 23.98 N ATOM 510 C5 C B 324 36.423 62.292 43.402 1.00 24.48 C ATOM 511 C6 C B 324 37.526 62.948 43.804 1.00 24.91 C ATOM 512 P A B 325 42.511 66.217 46.981 1.00 24.00 P ATOM 513 OP1 A B 325 42.316 66.752 48.362 1.00 24.08 O ATOM 514 OP2 A B 325 42.819 67.146 45.872 1.00 23.81 O ATOM 515 O5' A B 325 43.680 65.135 47.050 1.00 23.51 O ATOM 516 C5' A B 325 43.684 64.089 48.031 1.00 21.82 C ATOM 517 C4' A B 325 45.116 63.722 48.376 1.00 21.20 C ATOM 518 O4' A B 325 45.829 63.278 47.192 1.00 20.78 O ATOM 519 C3' A B 325 45.960 64.860 48.928 1.00 20.81 C ATOM 520 O3' A B 325 45.782 64.875 50.329 1.00 20.77 O ATOM 521 C2' A B 325 47.376 64.390 48.627 1.00 20.45 C ATOM 522 O2' A B 325 47.756 63.408 49.554 1.00 20.29 O ATOM 523 C1' A B 325 47.193 63.686 47.275 1.00 20.37 C ATOM 524 N9 A B 325 47.478 64.562 46.142 1.00 19.71 N ATOM 525 C8 A B 325 46.612 65.452 45.570 1.00 19.07 C ATOM 526 N7 A B 325 47.129 66.114 44.567 1.00 19.30 N ATOM 527 C5 A B 325 48.426 65.616 44.469 1.00 18.84 C ATOM 528 C6 A B 325 49.483 65.913 43.595 1.00 18.84 C ATOM 529 N6 A B 325 49.382 66.807 42.602 1.00 18.08 N ATOM 530 N1 A B 325 50.658 65.256 43.771 1.00 19.08 N ATOM 531 C2 A B 325 50.745 64.363 44.766 1.00 19.18 C ATOM 532 N3 A B 325 49.802 63.996 45.652 1.00 19.69 N ATOM 533 C4 A B 325 48.656 64.671 45.437 1.00 18.98 C ATOM 534 P G B 326 44.753 65.900 50.997 1.00 21.24 P ATOM 535 OP1 G B 326 43.491 65.137 51.205 1.00 21.13 O ATOM 536 OP2 G B 326 44.724 67.160 50.204 1.00 20.30 O ATOM 537 O5' G B 326 45.438 66.168 52.417 1.00 20.66 O ATOM 538 C5' G B 326 44.727 66.005 53.638 1.00 21.06 C ATOM 539 C4' G B 326 44.698 67.325 54.394 1.00 21.52 C ATOM 540 O4' G B 326 46.070 67.688 54.780 1.00 21.22 O ATOM 541 C3' G B 326 44.177 68.495 53.561 1.00 21.39 C ATOM 542 O3' G B 326 43.611 69.527 54.359 1.00 22.72 O ATOM 543 C2' G B 326 45.459 69.083 52.995 1.00 20.96 C ATOM 544 O2' G B 326 45.317 70.456 52.681 1.00 20.59 O ATOM 545 C1' G B 326 46.391 68.925 54.184 1.00 20.41 C ATOM 546 N9 G B 326 47.803 68.944 53.837 1.00 20.04 N ATOM 547 C8 G B 326 48.374 69.439 52.690 1.00 19.91 C ATOM 548 N7 G B 326 49.677 69.410 52.719 1.00 19.57 N ATOM 549 C5 G B 326 49.977 68.847 53.945 1.00 19.16 C ATOM 550 C6 G B 326 51.221 68.562 54.532 1.00 18.96 C ATOM 551 O6 G B 326 52.354 68.775 54.080 1.00 18.58 O ATOM 552 N1 G B 326 51.076 67.964 55.774 1.00 18.93 N ATOM 553 C2 G B 326 49.885 67.681 56.371 1.00 19.11 C ATOM 554 N2 G B 326 49.952 67.072 57.552 1.00 20.07 N ATOM 555 N3 G B 326 48.710 67.960 55.846 1.00 19.68 N ATOM 556 C4 G B 326 48.832 68.535 54.633 1.00 19.75 C ATOM 557 P U B 327 42.188 69.320 55.082 1.00 23.08 P ATOM 558 OP1 U B 327 41.559 68.044 54.701 1.00 23.91 O ATOM 559 OP2 U B 327 41.405 70.565 54.998 1.00 22.95 O ATOM 560 O5' U B 327 42.705 69.043 56.555 1.00 24.81 O ATOM 561 C5' U B 327 42.139 69.678 57.650 1.00 25.62 C ATOM 562 C4' U B 327 43.195 69.983 58.681 1.00 26.17 C ATOM 563 O4' U B 327 44.372 70.573 58.026 1.00 25.98 O ATOM 564 C3' U B 327 42.700 71.052 59.643 1.00 26.36 C ATOM 565 O3' U B 327 43.414 71.009 60.868 1.00 26.98 O ATOM 566 C2' U B 327 43.085 72.311 58.898 1.00 26.11 C ATOM 567 O2' U B 327 43.008 73.452 59.712 1.00 26.17 O ATOM 568 C1' U B 327 44.499 71.924 58.439 1.00 26.04 C ATOM 569 N1 U B 327 45.011 72.730 57.320 1.00 26.24 N ATOM 570 C2 U B 327 46.083 73.579 57.570 1.00 25.90 C ATOM 571 O2 U B 327 46.625 73.647 58.645 1.00 26.43 O ATOM 572 N3 U B 327 46.483 74.345 56.509 1.00 26.00 N ATOM 573 C4 U B 327 45.933 74.351 55.241 1.00 25.82 C ATOM 574 O4 U B 327 46.386 75.122 54.384 1.00 25.78 O ATOM 575 C5 U B 327 44.842 73.438 55.060 1.00 25.66 C ATOM 576 C6 U B 327 44.434 72.678 56.074 1.00 25.75 C ATOM 577 P G B 328 43.030 69.938 61.998 1.00 27.14 P ATOM 578 OP1 G B 328 41.991 68.992 61.527 1.00 27.63 O ATOM 579 OP2 G B 328 42.801 70.720 63.243 1.00 28.10 O ATOM 580 O5' G B 328 44.397 69.129 62.142 1.00 26.95 O ATOM 581 C5' G B 328 44.466 67.918 62.863 1.00 25.25 C ATOM 582 C4' G B 328 45.904 67.602 63.198 1.00 24.70 C ATOM 583 O4' G B 328 46.655 67.351 61.993 1.00 23.82 O ATOM 584 C3' G B 328 46.710 68.718 63.838 1.00 24.50 C ATOM 585 O3' G B 328 46.432 68.897 65.206 1.00 25.57 O ATOM 586 C2' G B 328 48.123 68.201 63.670 1.00 24.09 C ATOM 587 O2' G B 328 48.381 67.181 64.622 1.00 23.72 O ATOM 588 C1' G B 328 48.038 67.573 62.271 1.00 23.46 C ATOM 589 N9 G B 328 48.609 68.423 61.230 1.00 22.30 N ATOM 590 C8 G B 328 47.931 69.136 60.271 1.00 21.41 C ATOM 591 N7 G B 328 48.729 69.766 59.450 1.00 21.33 N ATOM 592 C5 G B 328 50.006 69.464 59.904 1.00 20.85 C ATOM 593 C6 G B 328 51.263 69.849 59.397 1.00 20.69 C ATOM 594 O6 G B 328 51.518 70.548 58.392 1.00 21.07 O ATOM 595 N1 G B 328 52.301 69.331 60.148 1.00 20.18 N ATOM 596 C2 G B 328 52.157 68.520 61.240 1.00 20.75 C ATOM 597 N2 G B 328 53.305 68.145 61.833 1.00 20.04 N ATOM 598 N3 G B 328 50.980 68.119 61.714 1.00 20.90 N ATOM 599 C4 G B 328 49.953 68.640 61.001 1.00 21.34 C ATOM 600 P C B 329 46.294 70.390 65.787 1.00 26.40 P ATOM 601 OP1 C B 329 46.081 70.211 67.251 1.00 26.83 O ATOM 602 OP2 C B 329 45.306 71.168 64.975 1.00 25.83 O ATOM 603 O5' C B 329 47.773 70.957 65.599 1.00 26.86 O ATOM 604 C5' C B 329 48.848 70.288 66.266 1.00 27.27 C ATOM 605 C4' C B 329 50.185 70.756 65.756 1.00 27.90 C ATOM 606 O4' C B 329 50.394 70.340 64.384 1.00 27.63 O ATOM 607 C3' C B 329 50.429 72.258 65.715 1.00 28.73 C ATOM 608 O3' C B 329 50.743 72.767 67.009 1.00 30.32 O ATOM 609 C2' C B 329 51.646 72.330 64.801 1.00 28.43 C ATOM 610 O2' C B 329 52.826 71.913 65.463 1.00 28.58 O ATOM 611 C1' C B 329 51.309 71.240 63.768 1.00 27.66 C ATOM 612 N1 C B 329 50.685 71.824 62.573 1.00 26.32 N ATOM 613 C2 C B 329 51.522 72.291 61.561 1.00 25.93 C ATOM 614 O2 C B 329 52.745 72.169 61.705 1.00 25.69 O ATOM 615 N3 C B 329 50.989 72.851 60.459 1.00 25.21 N ATOM 616 C4 C B 329 49.671 72.952 60.339 1.00 25.35 C ATOM 617 N4 C B 329 49.194 73.516 59.234 1.00 25.03 N ATOM 618 C5 C B 329 48.781 72.481 61.355 1.00 25.70 C ATOM 619 C6 C B 329 49.328 71.925 62.449 1.00 25.91 C ATOM 620 P G B 330 50.322 74.267 67.411 1.00 32.03 P ATOM 621 OP1 G B 330 51.265 75.162 66.664 1.00 31.78 O ATOM 622 OP2 G B 330 50.228 74.350 68.887 1.00 31.18 O ATOM 623 O5' G B 330 48.866 74.480 66.804 1.00 31.05 O ATOM 624 C5' G B 330 48.104 75.625 67.143 1.00 30.70 C ATOM 625 C4' G B 330 46.941 75.745 66.203 1.00 30.73 C ATOM 626 O4' G B 330 47.375 76.405 64.977 1.00 30.27 O ATOM 627 C3' G B 330 46.357 74.410 65.766 1.00 30.81 C ATOM 628 O3' G B 330 44.979 74.590 65.518 1.00 32.45 O ATOM 629 C2' G B 330 47.095 74.139 64.455 1.00 30.22 C ATOM 630 O2' G B 330 46.392 73.317 63.566 1.00 29.96 O ATOM 631 C1' G B 330 47.177 75.538 63.865 1.00 29.55 C ATOM 632 N9 G B 330 48.299 75.729 62.955 1.00 28.44 N ATOM 633 C8 G B 330 49.630 75.577 63.260 1.00 28.19 C ATOM 634 N7 G B 330 50.421 75.923 62.284 1.00 27.38 N ATOM 635 C5 G B 330 49.559 76.303 61.264 1.00 27.07 C ATOM 636 C6 G B 330 49.841 76.786 59.972 1.00 26.73 C ATOM 637 O6 G B 330 50.950 76.990 59.453 1.00 25.93 O ATOM 638 N1 G B 330 48.672 77.044 59.255 1.00 26.61 N ATOM 639 C2 G B 330 47.395 76.859 59.734 1.00 26.63 C ATOM 640 N2 G B 330 46.396 77.157 58.895 1.00 26.16 N ATOM 641 N3 G B 330 47.124 76.420 60.943 1.00 27.01 N ATOM 642 C4 G B 330 48.246 76.163 61.651 1.00 27.44 C ATOM 643 P A B 331 43.911 73.788 66.400 1.00 33.59 P ATOM 644 OP1 A B 331 44.497 72.560 66.991 1.00 33.54 O ATOM 645 OP2 A B 331 42.687 73.710 65.593 1.00 34.27 O ATOM 646 O5' A B 331 43.649 74.756 67.622 1.00 35.44 O ATOM 647 C5' A B 331 42.479 75.509 67.659 1.00 35.63 C ATOM 648 C4' A B 331 42.783 76.945 67.942 1.00 36.14 C ATOM 649 O4' A B 331 44.107 77.365 67.507 1.00 35.90 O ATOM 650 C3' A B 331 41.836 77.840 67.184 1.00 36.65 C ATOM 651 O3' A B 331 40.596 77.788 67.845 1.00 37.29 O ATOM 652 C2' A B 331 42.580 79.169 67.140 1.00 36.49 C ATOM 653 O2' A B 331 42.415 79.938 68.312 1.00 37.17 O ATOM 654 C1' A B 331 44.037 78.698 66.992 1.00 35.91 C ATOM 655 N9 A B 331 44.416 78.649 65.585 1.00 35.56 N ATOM 656 C8 A B 331 44.391 77.537 64.782 1.00 35.25 C ATOM 657 N7 A B 331 44.714 77.776 63.541 1.00 34.72 N ATOM 658 C5 A B 331 44.995 79.129 63.525 1.00 34.55 C ATOM 659 C6 A B 331 45.400 79.981 62.499 1.00 34.41 C ATOM 660 N6 A B 331 45.595 79.570 61.246 1.00 33.95 N ATOM 661 N1 A B 331 45.601 81.286 62.802 1.00 34.66 N ATOM 662 C2 A B 331 45.397 81.685 64.061 1.00 34.31 C ATOM 663 N3 A B 331 45.010 80.967 65.120 1.00 34.90 N ATOM 664 C4 A B 331 44.827 79.681 64.778 1.00 34.97 C ATOM 665 P G B 332 39.308 78.338 67.097 1.00 38.91 P ATOM 666 OP1 G B 332 38.182 78.188 68.087 1.00 38.82 O ATOM 667 OP2 G B 332 39.196 77.690 65.746 1.00 38.65 O ATOM 668 O5' G B 332 39.724 79.858 66.878 1.00 37.89 O ATOM 669 C5' G B 332 39.137 80.643 65.875 1.00 37.81 C ATOM 670 C4' G B 332 39.954 81.898 65.674 1.00 38.12 C ATOM 671 O4' G B 332 41.289 81.562 65.206 1.00 37.64 O ATOM 672 C3' G B 332 39.393 82.831 64.619 1.00 38.62 C ATOM 673 O3' G B 332 38.408 83.657 65.224 1.00 39.70 O ATOM 674 C2' G B 332 40.626 83.596 64.149 1.00 38.13 C ATOM 675 O2' G B 332 40.943 84.684 64.988 1.00 38.54 O ATOM 676 C1' G B 332 41.717 82.527 64.252 1.00 37.45 C ATOM 677 N9 G B 332 41.988 81.847 62.984 1.00 36.51 N ATOM 678 C8 G B 332 41.838 80.503 62.714 1.00 36.12 C ATOM 679 N7 G B 332 42.156 80.190 61.482 1.00 35.58 N ATOM 680 C5 G B 332 42.544 81.393 60.904 1.00 35.37 C ATOM 681 C6 G B 332 42.999 81.674 59.595 1.00 34.96 C ATOM 682 O6 G B 332 43.167 80.899 58.649 1.00 34.72 O ATOM 683 N1 G B 332 43.281 83.016 59.429 1.00 34.66 N ATOM 684 C2 G B 332 43.156 83.974 60.389 1.00 34.75 C ATOM 685 N2 G B 332 43.506 85.202 59.997 1.00 34.57 N ATOM 686 N3 G B 332 42.730 83.741 61.623 1.00 35.12 N ATOM 687 C4 G B 332 42.444 82.431 61.811 1.00 35.68 C ATOM 688 P C B 333 37.140 84.133 64.371 1.00 41.12 P ATOM 689 OP1 C B 333 36.243 84.830 65.332 1.00 41.30 O ATOM 690 OP2 C B 333 36.616 82.967 63.588 1.00 40.95 O ATOM 691 O5' C B 333 37.749 85.209 63.359 1.00 40.87 O ATOM 692 C5' C B 333 38.262 86.445 63.843 1.00 40.96 C ATOM 693 C4' C B 333 38.853 87.248 62.717 1.00 40.97 C ATOM 694 O4' C B 333 40.029 86.575 62.209 1.00 40.94 O ATOM 695 C3' C B 333 37.965 87.406 61.498 1.00 41.21 C ATOM 696 O3' C B 333 36.987 88.420 61.665 1.00 41.87 O ATOM 697 C2' C B 333 38.979 87.717 60.405 1.00 41.17 C ATOM 698 O2' C B 333 39.454 89.052 60.436 1.00 40.60 O ATOM 699 C1' C B 333 40.116 86.773 60.799 1.00 40.98 C ATOM 700 N1 C B 333 40.004 85.453 60.145 1.00 40.72 N ATOM 701 C2 C B 333 40.389 85.322 58.807 1.00 40.65 C ATOM 702 O2 C B 333 40.791 86.339 58.193 1.00 40.38 O ATOM 703 N3 C B 333 40.311 84.089 58.216 1.00 40.06 N ATOM 704 C4 C B 333 39.868 83.039 58.918 1.00 39.96 C ATOM 705 N4 C B 333 39.810 81.848 58.320 1.00 39.96 N ATOM 706 C5 C B 333 39.462 83.157 60.270 1.00 40.21 C ATOM 707 C6 C B 333 39.540 84.369 60.839 1.00 40.74 C ATOM 708 P A B 334 35.553 88.264 60.947 1.00 42.67 P ATOM 709 OP1 A B 334 34.720 89.443 61.330 1.00 43.07 O ATOM 710 OP2 A B 334 35.062 86.884 61.244 1.00 42.24 O ATOM 711 O5' A B 334 35.876 88.415 59.394 1.00 41.98 O ATOM 712 C5' A B 334 36.491 89.597 58.905 1.00 41.69 C ATOM 713 C4' A B 334 36.985 89.396 57.489 1.00 41.68 C ATOM 714 O4' A B 334 37.991 88.344 57.442 1.00 41.29 O ATOM 715 C3' A B 334 35.942 88.947 56.479 1.00 41.80 C ATOM 716 O3' A B 334 35.149 90.043 56.032 1.00 42.52 O ATOM 717 C2' A B 334 36.813 88.367 55.370 1.00 41.38 C ATOM 718 O2' A B 334 37.434 89.383 54.604 1.00 41.31 O ATOM 719 C1' A B 334 37.898 87.664 56.191 1.00 40.86 C ATOM 720 N9 A B 334 37.590 86.265 56.469 1.00 40.01 N ATOM 721 C8 A B 334 37.089 85.749 57.638 1.00 39.60 C ATOM 722 N7 A B 334 36.960 84.442 57.630 1.00 39.28 N ATOM 723 C5 A B 334 37.398 84.075 56.367 1.00 39.10 C ATOM 724 C6 A B 334 37.518 82.827 55.741 1.00 38.69 C ATOM 725 N6 A B 334 37.197 81.672 56.333 1.00 38.24 N ATOM 726 N1 A B 334 37.986 82.802 54.474 1.00 38.50 N ATOM 727 C2 A B 334 38.297 83.961 53.878 1.00 38.66 C ATOM 728 N3 A B 334 38.221 85.204 54.363 1.00 39.25 N ATOM 729 C4 A B 334 37.768 85.190 55.631 1.00 39.42 C ATOM 730 P A B 335 33.581 89.826 55.716 1.00 43.18 P ATOM 731 OP1 A B 335 32.982 91.165 55.418 1.00 43.30 O ATOM 732 OP2 A B 335 32.987 88.959 56.781 1.00 43.10 O ATOM 733 O5' A B 335 33.578 89.042 54.336 1.00 42.66 O ATOM 734 C5' A B 335 34.158 89.638 53.187 1.00 42.04 C ATOM 735 C4' A B 335 34.287 88.612 52.113 1.00 41.65 C ATOM 736 O4' A B 335 35.195 87.576 52.569 1.00 41.19 O ATOM 737 C3' A B 335 33.004 87.863 51.792 1.00 41.49 C ATOM 738 O3' A B 335 32.049 88.694 51.073 1.00 41.63 O ATOM 739 C2' A B 335 33.543 86.579 51.174 1.00 41.17 C ATOM 740 O2' A B 335 34.011 86.752 49.842 1.00 41.27 O ATOM 741 C1' A B 335 34.772 86.327 52.057 1.00 40.77 C ATOM 742 N9 A B 335 34.497 85.448 53.190 1.00 40.05 N ATOM 743 C8 A B 335 34.011 85.804 54.415 1.00 39.63 C ATOM 744 N7 A B 335 33.839 84.788 55.229 1.00 39.60 N ATOM 745 C5 A B 335 34.257 83.691 54.490 1.00 39.19 C ATOM 746 C6 A B 335 34.323 82.315 54.789 1.00 39.16 C ATOM 747 N6 A B 335 33.939 81.792 55.961 1.00 38.72 N ATOM 748 N1 A B 335 34.791 81.481 53.829 1.00 38.86 N ATOM 749 C2 A B 335 35.147 82.005 52.652 1.00 39.04 C ATOM 750 N3 A B 335 35.119 83.280 52.250 1.00 39.25 N ATOM 751 C4 A B 335 34.665 84.080 53.232 1.00 39.45 C TER 752 A B 335 HETATM 753 CO CNC B 801 54.614 81.361 60.981 1.00 33.90 CO HETATM 754 N21 CNC B 801 54.928 80.010 62.280 1.00 32.60 N HETATM 755 N22 CNC B 801 56.480 81.341 60.460 1.00 32.96 N HETATM 756 N23 CNC B 801 54.067 82.754 59.714 1.00 33.04 N HETATM 757 N24 CNC B 801 52.797 81.206 61.530 1.00 32.92 N HETATM 758 C1 CNC B 801 53.799 79.669 63.205 1.00 32.84 C HETATM 759 C20 CNC B 801 53.813 80.588 64.435 1.00 32.95 C HETATM 760 C2 CNC B 801 54.147 78.115 63.611 1.00 32.89 C HETATM 761 C25 CNC B 801 53.526 77.710 64.966 1.00 32.73 C HETATM 762 C26 CNC B 801 53.692 77.128 62.491 1.00 33.36 C HETATM 763 C27 CNC B 801 54.144 75.690 62.622 1.00 33.34 C HETATM 764 O28 CNC B 801 55.332 75.338 62.685 1.00 34.58 O HETATM 765 N29 CNC B 801 53.145 74.800 62.666 1.00 34.46 N HETATM 766 C3 CNC B 801 55.704 78.204 63.592 1.00 32.78 C HETATM 767 C30 CNC B 801 56.470 78.569 64.868 1.00 32.49 C HETATM 768 C31 CNC B 801 57.008 77.322 65.598 1.00 32.42 C HETATM 769 C32 CNC B 801 57.748 77.674 66.840 1.00 33.08 C HETATM 770 O34 CNC B 801 58.970 78.019 66.750 1.00 32.94 O HETATM 771 N33 CNC B 801 57.093 77.624 68.004 1.00 32.61 N HETATM 772 C4 CNC B 801 55.937 79.190 62.448 1.00 32.64 C HETATM 773 C5 CNC B 801 57.189 79.291 61.707 1.00 32.53 C HETATM 774 C35 CNC B 801 58.173 78.125 61.905 1.00 32.46 C HETATM 775 C6 CNC B 801 57.428 80.327 60.805 1.00 32.79 C HETATM 776 C7 CNC B 801 58.664 80.599 59.875 1.00 32.85 C HETATM 777 C36 CNC B 801 60.068 80.339 60.487 1.00 32.71 C HETATM 778 C37 CNC B 801 58.350 79.719 58.608 1.00 32.50 C HETATM 779 C38 CNC B 801 59.387 79.802 57.507 1.00 32.35 C HETATM 780 O39 CNC B 801 59.114 80.436 56.498 1.00 32.29 O HETATM 781 N40 CNC B 801 60.543 79.158 57.687 1.00 31.81 N HETATM 782 C8 CNC B 801 58.510 82.119 59.560 1.00 33.25 C HETATM 783 C41 CNC B 801 59.200 83.079 60.576 1.00 33.74 C HETATM 784 C42 CNC B 801 58.907 84.589 60.427 1.00 34.59 C HETATM 785 C43 CNC B 801 59.575 85.424 61.427 1.00 34.92 C HETATM 786 O44 CNC B 801 60.373 84.972 62.297 1.00 35.58 O HETATM 787 N45 CNC B 801 59.299 86.734 61.405 1.00 35.44 N HETATM 788 C9 CNC B 801 57.000 82.230 59.640 1.00 33.08 C HETATM 789 C10 CNC B 801 56.311 83.176 58.899 1.00 33.29 C HETATM 790 C11 CNC B 801 54.950 83.346 58.887 1.00 33.51 C HETATM 791 C12 CNC B 801 54.230 84.234 57.834 1.00 33.85 C HETATM 792 C46 CNC B 801 54.040 83.424 56.553 1.00 33.95 C HETATM 793 C47 CNC B 801 55.084 85.493 57.433 1.00 34.50 C HETATM 794 C13 CNC B 801 52.903 84.482 58.513 1.00 34.21 C HETATM 795 C48 CNC B 801 52.784 85.772 59.370 1.00 35.04 C HETATM 796 C49 CNC B 801 52.169 87.052 58.680 1.00 36.57 C HETATM 797 C50 CNC B 801 50.787 87.414 59.179 1.00 37.48 C HETATM 798 O51 CNC B 801 50.190 88.372 58.639 1.00 38.93 O HETATM 799 N52 CNC B 801 50.217 86.700 60.194 1.00 37.54 N HETATM 800 C14 CNC B 801 52.822 83.257 59.464 1.00 33.48 C HETATM 801 C15 CNC B 801 51.657 82.830 60.105 1.00 32.91 C HETATM 802 C53 CNC B 801 50.343 83.524 59.694 1.00 32.72 C HETATM 803 C16 CNC B 801 51.654 81.776 61.128 1.00 32.99 C HETATM 804 C17 CNC B 801 50.450 81.134 61.833 1.00 33.38 C HETATM 805 C54 CNC B 801 49.770 80.145 60.839 1.00 33.23 C HETATM 806 C55 CNC B 801 49.407 82.133 62.429 1.00 33.50 C HETATM 807 C56 CNC B 801 49.946 83.306 63.241 1.00 34.17 C HETATM 808 C57 CNC B 801 48.903 84.381 63.503 1.00 34.78 C HETATM 809 O58 CNC B 801 48.685 85.284 62.631 1.00 34.82 O HETATM 810 N59 CNC B 801 48.256 84.303 64.683 1.00 34.75 N HETATM 811 C18 CNC B 801 51.171 80.417 63.024 1.00 33.09 C HETATM 812 C60 CNC B 801 50.394 79.242 63.680 1.00 33.30 C HETATM 813 C61 CNC B 801 49.642 79.701 64.956 1.00 33.66 C HETATM 814 O63 CNC B 801 48.544 79.026 65.294 1.00 34.45 O HETATM 815 N62 CNC B 801 50.070 80.637 65.576 1.00 34.22 N HETATM 816 C19 CNC B 801 52.497 80.040 62.385 1.00 33.02 C HETATM 817 C1P CNC B 801 47.218 85.248 65.088 1.00 35.34 C HETATM 818 C2P CNC B 801 47.770 86.579 65.537 1.00 35.71 C HETATM 819 C3P CNC B 801 46.687 87.613 65.892 1.00 35.59 C HETATM 820 O3 CNC B 801 48.612 86.297 66.735 1.00 35.53 O HETATM 821 O4 CNC B 801 49.944 88.426 66.429 1.00 35.30 O HETATM 822 O5 CNC B 801 50.699 86.489 68.005 1.00 35.48 O HETATM 823 P CNC B 801 50.050 86.941 66.713 1.00 35.91 P HETATM 824 O2 CNC B 801 50.726 86.265 65.449 1.00 35.33 O HETATM 825 C3R CNC B 801 51.999 86.775 64.939 1.00 34.79 C HETATM 826 C2R CNC B 801 53.133 85.834 65.132 1.00 34.43 C HETATM 827 O7R CNC B 801 52.710 84.485 65.109 1.00 34.71 O HETATM 828 C1R CNC B 801 54.007 86.129 63.894 1.00 34.24 C HETATM 829 O6R CNC B 801 53.144 86.676 62.882 1.00 34.31 O HETATM 830 C4R CNC B 801 51.887 87.080 63.475 1.00 34.85 C HETATM 831 C5R CNC B 801 51.584 88.590 63.167 1.00 35.26 C HETATM 832 O8R CNC B 801 52.754 89.393 62.698 1.00 36.95 O HETATM 833 N1B CNC B 801 54.681 84.883 63.421 1.00 34.40 N HETATM 834 C8B CNC B 801 55.951 84.390 63.901 1.00 34.13 C HETATM 835 C2B CNC B 801 54.215 83.963 62.543 1.00 33.83 C HETATM 836 N3B CNC B 801 55.017 82.868 62.379 1.00 33.36 N HETATM 837 C9B CNC B 801 56.123 83.156 63.254 1.00 33.75 C HETATM 838 C4B CNC B 801 57.322 82.387 63.568 1.00 33.69 C HETATM 839 C5B CNC B 801 58.268 82.908 64.484 1.00 33.60 C HETATM 840 C5M CNC B 801 59.523 82.059 64.779 1.00 33.27 C HETATM 841 C6B CNC B 801 58.082 84.174 65.121 1.00 33.58 C HETATM 842 C6M CNC B 801 59.096 84.724 66.098 1.00 32.92 C HETATM 843 C7B CNC B 801 56.890 84.944 64.829 1.00 33.98 C HETATM 844 N1A CNC B 801 54.161 79.206 58.899 1.00 32.15 N HETATM 845 C1A CNC B 801 54.311 80.037 59.678 1.00 33.18 C HETATM 846 O HOH B1105 53.839 57.780 52.896 1.06 9.87 O HETATM 847 O HOH B1106 56.027 80.899 54.879 0.91 6.12 O HETATM 848 O HOH B1111 47.535 65.170 55.739 0.86 17.88 O HETATM 849 O HOH B1116 58.941 60.369 53.860 1.06 10.36 O HETATM 850 O HOH B1121 47.523 79.259 68.071 1.02 13.45 O HETATM 851 O HOH B1127 46.351 69.091 45.185 0.80 13.53 O HETATM 852 O HOH B1129 48.849 70.793 41.926 1.06 14.82 O HETATM 853 O HOH B1133 44.029 71.922 47.955 0.91 17.98 O HETATM 854 O HOH B1137 53.885 78.727 56.147 0.76 14.78 O HETATM 855 O HOH B1140 61.458 80.186 54.024 0.95 18.01 O HETATM 856 O HOH B1141 41.417 66.532 50.951 0.80 21.08 O HETATM 857 O HOH B1148 50.667 70.341 50.230 0.86 30.54 O HETATM 858 O HOH B1149 57.993 56.366 55.501 0.95 23.32 O HETATM 859 O HOH B1155 47.146 68.063 49.643 0.93 20.24 O HETATM 860 O HOH B1158 41.279 67.813 40.092 0.92 7.06 O HETATM 861 O HOH B1159 54.164 71.595 54.266 0.83 14.27 O HETATM 862 O HOH B1164 52.199 73.575 58.169 0.74 10.85 O HETATM 863 O HOH B1169 38.848 79.518 59.505 1.05 23.96 O HETATM 864 O HOH B1170 49.890 66.836 38.543 1.00 19.55 O HETATM 865 O HOH B1171 52.911 60.626 41.832 1.08 25.36 O HETATM 866 O HOH B1173 42.124 60.867 46.108 1.01 24.78 O HETATM 867 O HOH B1179 55.565 74.198 55.135 0.95 25.73 O HETATM 868 O HOH B1192 43.380 75.640 57.872 0.87 25.24 O HETATM 869 O HOH B1197 41.231 69.296 45.031 0.91 27.51 O HETATM 870 O HOH B1203 54.521 74.364 66.304 0.88 25.73 O HETATM 871 O HOH B1204 44.689 67.249 43.416 0.84 22.07 O HETATM 872 O HOH B1205 55.224 72.130 63.182 0.79 19.14 O HETATM 873 O HOH B1206 59.024 84.903 56.597 0.98 25.87 O HETATM 874 O HOH B1212 57.399 62.478 51.616 0.85 22.26 O HETATM 875 O HOH B1214 39.508 60.093 44.400 1.08 32.58 O HETATM 876 O HOH B1218 54.027 73.715 52.607 0.85 20.61 O HETATM 877 O HOH B1225 59.476 52.034 53.314 1.35 39.71 O HETATM 878 O HOH B1227 57.039 64.781 53.370 0.92 18.84 O HETATM 879 O HOH B1229 61.056 78.286 69.369 1.08 31.08 O HETATM 880 O HOH B1230 43.876 66.193 40.612 0.76 15.27 O HETATM 881 O HOH B1231 46.932 68.270 42.249 0.75 12.00 O HETATM 882 O HOH B1241 54.160 74.296 49.737 0.83 15.55 O HETATM 883 O HOH B1242 59.471 69.116 51.968 0.89 28.34 O HETATM 884 O HOH B1244 34.797 59.981 41.284 0.89 26.08 O HETATM 885 O HOH B1248 56.861 67.575 53.744 1.07 31.73 O HETATM 886 O HOH B1249 45.915 90.872 50.934 0.95 34.40 O HETATM 887 O HOH B1252 68.046 49.364 61.028 1.06 34.56 O HETATM 888 O HOH B1259 59.326 66.475 48.680 0.92 21.54 O HETATM 889 O HOH B1261 63.994 71.060 52.929 1.13 32.33 O HETATM 890 O HOH B1266 47.272 86.515 60.468 0.93 33.96 O HETATM 891 O HOH B1269 40.273 64.777 49.232 0.77 15.07 O HETATM 892 O HOH B1273 51.006 66.004 63.654 0.93 40.90 O HETATM 893 O HOH B1276 44.195 87.947 61.795 1.13 38.07 O HETATM 894 O HOH B1278 62.471 58.514 57.756 1.10 48.96 O HETATM 895 O HOH B1285 45.343 82.461 67.638 0.89 38.42 O HETATM 896 O HOH B1291 30.064 89.957 50.328 1.10 34.77 O HETATM 897 O HOH B1292 44.338 69.149 47.498 0.85 21.13 O HETATM 898 O HOH B1293 53.355 76.310 58.524 0.83 17.95 O HETATM 899 O HOH B1295 57.135 67.387 50.345 1.05 36.51 O HETATM 900 O HOH B1300 55.043 86.695 53.677 0.93 26.02 O HETATM 901 O HOH B1305 53.341 70.244 52.025 0.92 24.74 O HETATM 902 O HOH B1307 57.194 65.883 63.929 1.02 35.94 O HETATM 903 O HOH B1310 43.971 73.963 61.850 0.70 23.37 O HETATM 904 O HOH B1313 41.582 63.503 52.678 0.71 11.27 O HETATM 905 O HOH B1316 45.192 70.328 38.491 0.79 27.09 O HETATM 906 O HOH B1317 41.753 79.403 54.989 0.80 21.22 O HETATM 907 O HOH B1320 42.848 76.279 53.274 1.02 34.19 O HETATM 908 O HOH B1326 64.004 71.848 61.751 0.82 32.32 O HETATM 909 O HOH B1333 44.050 75.573 50.477 0.83 22.14 O HETATM 910 O HOH B1349 63.039 75.121 54.691 0.88 32.11 O HETATM 911 O HOH B1351 57.405 87.465 58.640 0.98 49.27 O HETATM 912 O HOH B1355 51.076 59.929 43.795 0.97 39.04 O HETATM 913 O HOH B1357 44.484 57.556 55.374 0.96 38.99 O HETATM 914 O HOH B1359 42.600 70.216 65.955 0.91 21.76 O HETATM 915 O HOH B1362 43.824 58.494 40.666 0.93 32.06 O HETATM 916 O HOH B1364 48.724 83.179 66.695 1.06 41.35 O HETATM 917 O HOH B1367 38.095 61.381 39.470 1.09 41.48 O HETATM 918 O HOH B1370 46.945 85.307 45.934 1.04 33.78 O HETATM 919 O HOH B1382 56.726 70.615 49.436 0.91 35.09 O HETATM 920 O HOH B1385 41.319 77.652 60.801 0.94 37.26 O HETATM 921 O HOH B1386 44.064 57.572 46.725 0.82 43.73 O HETATM 922 O HOH B1388 61.429 68.756 62.586 0.83 21.26 O HETATM 923 O HOH B1389 59.323 74.958 62.388 0.99 38.97 O HETATM 924 O HOH B1394 57.734 71.248 44.352 0.84 31.32 O HETATM 925 O HOH B1402 52.860 57.217 58.371 0.95 39.14 O HETATM 926 O HOH B1406 58.520 64.395 50.147 0.94 28.92 O HETATM 927 O HOH B1412 50.665 57.280 53.468 1.00 45.67 O HETATM 928 O HOH B1414 43.899 59.078 51.679 0.84 38.97 O HETATM 929 O HOH B1417 67.744 58.041 56.450 0.97 41.07 O HETATM 930 O HOH B1420 51.937 83.364 67.210 0.93 39.43 O HETATM 931 O HOH B1445 42.686 62.047 50.620 0.90 32.56 O HETATM 932 O HOH B1450 64.003 44.316 63.670 1.27 44.15 O HETATM 933 O HOH B1456 42.515 72.017 52.767 1.22 46.83 O HETATM 934 O HOH B1462 61.158 62.242 41.303 0.87 37.94 O HETATM 935 O HOH B1468 62.846 78.922 55.928 0.93 26.37 O HETATM 936 O HOH B1469 46.452 75.164 45.153 1.02 35.05 O HETATM 937 O HOH B1474 41.870 74.523 63.381 0.78 34.92 O HETATM 938 O HOH B1478 60.044 53.774 57.656 0.89 49.38 O HETATM 939 O HOH B1485 50.200 56.142 49.412 0.99 37.28 O HETATM 940 O HOH B1486 51.272 86.614 50.437 0.98 42.13 O HETATM 941 O HOH B1487 44.147 77.781 56.009 0.82 29.96 O HETATM 942 O HOH B1489 65.166 48.266 62.269 1.12 49.90 O HETATM 943 O HOH B1490 61.901 71.619 64.987 1.23 58.50 O HETATM 944 O HOH B1494 45.345 63.923 64.444 1.03 29.42 O HETATM 945 O HOH B1496 58.826 60.187 59.007 0.95 39.65 O HETATM 946 O HOH B1498 61.156 82.957 56.854 0.90 45.83 O HETATM 947 O HOH B1500 36.334 58.215 42.451 0.96 33.79 O HETATM 948 O HOH B1506 51.700 78.921 47.894 1.16 47.89 O HETATM 949 O HOH B1517 40.601 65.545 39.058 1.05 53.64 O HETATM 950 O HOH B1518 46.972 71.544 43.991 0.95 33.31 O HETATM 951 O HOH B1522 67.722 55.767 54.298 0.87 31.40 O HETATM 952 O HOH B1524 68.460 52.671 58.840 1.23 49.52 O HETATM 953 O HOH B1525 51.381 47.205 58.614 0.98 48.10 O HETATM 954 O HOH B1531 40.523 60.125 49.563 0.73 24.63 O HETATM 955 O HOH B1537 59.365 50.734 58.000 0.96 38.75 O HETATM 956 O HOH B1542 64.703 69.477 48.378 0.97 35.90 O HETATM 957 O HOH B1549 55.378 61.473 55.267 0.72 31.39 O HETATM 958 O HOH B1551 57.289 65.807 39.652 1.03 51.00 O HETATM 959 O HOH B1555 49.462 75.798 44.800 1.05 34.95 O HETATM 960 O HOH B1563 42.408 69.537 49.691 0.81 50.62 O HETATM 961 O HOH B1565 60.533 64.057 51.954 0.94 35.75 O HETATM 962 O HOH B1568 45.728 58.254 58.102 0.85 31.43 O HETATM 963 O HOH B1569 61.632 75.576 50.899 0.89 33.32 O HETATM 964 O HOH B1579 52.758 73.639 45.748 0.91 40.59 O HETATM 965 O HOH B1582 35.652 91.497 62.498 1.12 42.53 O HETATM 966 O HOH B1583 40.407 72.841 56.197 0.74 27.23 O HETATM 967 O HOH B1589 37.846 78.804 55.056 0.97 37.89 O HETATM 968 O HOH B1593 46.306 90.261 68.309 1.03 39.41 O HETATM 969 O HOH B1595 29.406 87.218 50.109 1.12 46.99 O HETATM 970 O HOH B1602 53.686 65.064 39.496 0.87 37.11 O HETATM 971 O HOH B1606 52.389 70.368 40.977 0.80 38.67 O HETATM 972 O HOH B1608 54.092 80.402 47.911 0.79 36.65 O HETATM 973 O HOH B1612 60.625 78.017 64.500 1.00 43.64 O HETATM 974 O HOH B1629 59.089 62.163 63.269 0.86 50.83 O HETATM 975 O HOH B1634 66.477 58.566 49.815 0.89 39.83 O HETATM 976 O HOH B1635 47.913 56.196 54.897 0.72 30.36 O HETATM 977 O HOH B1636 52.119 90.723 59.738 1.10 47.28 O HETATM 978 O HOH B1640 53.988 71.729 47.024 0.87 39.01 O HETATM 979 O HOH B1645 56.176 69.599 52.130 0.71 47.17 O HETATM 980 O HOH B1648 52.945 71.411 49.358 0.77 46.63 O HETATM 981 O HOH B1651 43.787 76.902 60.822 0.86 47.89 O HETATM 982 O HOH B1652 62.297 76.469 56.722 0.91 40.20 O HETATM 983 O HOH B1653 43.254 78.916 51.984 0.97 28.60 O HETATM 984 O HOH B1654 45.922 67.829 39.569 0.75 44.44 O HETATM 985 O HOH B1656 50.951 76.500 48.401 0.91 36.26 O HETATM 986 O HOH B1660 63.250 78.609 70.681 0.93 45.91 O HETATM 987 O HOH B1663 68.062 56.990 51.680 0.88 39.44 O HETATM 988 O HOH B1666 61.405 73.009 62.852 0.84 41.87 O HETATM 989 O HOH B1667 39.840 76.338 51.388 1.00 39.72 O HETATM 990 O HOH B1675 43.664 78.515 49.547 0.95 32.47 O HETATM 991 O HOH B1680 42.696 72.644 50.367 1.18 49.13 O HETATM 992 O HOH B1681 41.911 75.408 55.780 0.84 46.85 O HETATM 993 O HOH B1698 38.273 80.599 52.750 0.93 39.11 O HETATM 994 O HOH B1703 38.058 80.174 61.794 1.06 49.37 O HETATM 995 O HOH B1707 56.700 74.018 64.432 0.85 47.00 O HETATM 996 O HOH B1709 54.562 76.928 68.739 0.92 51.79 O HETATM 997 O HOH B1716 57.303 80.106 52.966 1.01 45.52 O HETATM 998 O HOH B1721 42.764 78.097 58.575 0.87 43.38 O HETATM 999 O HOH B1722 47.020 60.471 59.275 0.94 47.78 O HETATM 1000 O HOH B1725 50.484 90.745 65.170 0.98 48.06 O HETATM 1001 O HOH B1726 45.571 55.940 53.290 0.83 46.17 O HETATM 1002 O HOH B1730 57.133 63.294 55.218 0.71 45.58 O HETATM 1003 O HOH B1737 60.292 60.327 61.167 0.95 51.62 O HETATM 1004 O HOH B1747 40.785 62.463 38.085 1.02 43.29 O HETATM 1005 O HOH B1749 61.645 70.898 60.546 0.89 45.21 O HETATM 1006 O HOH B1755 40.934 77.126 63.729 0.74 45.16 O HETATM 1007 O HOH B1765 57.919 70.837 41.744 0.92 45.82 O HETATM 1008 O HOH B1774 39.559 62.256 50.349 0.89 45.21 O HETATM 1009 O HOH B1777 61.070 88.460 60.126 0.91 40.01 O HETATM 1010 O HOH B1783 65.408 62.991 61.492 0.91 47.77 O HETATM 1011 O HOH B1787 36.939 92.654 53.024 0.99 40.21 O HETATM 1012 O HOH B1788 60.786 64.810 55.133 0.79 50.92 O HETATM 1013 O HOH B1795 52.258 67.366 36.988 0.95 41.80 O HETATM 1014 O HOH B1796 61.437 42.643 63.300 0.81 51.61 O HETATM 1015 O HOH B1800 40.132 70.492 66.765 0.85 36.05 O HETATM 1016 O HOH B1801 39.226 71.224 58.103 0.74 39.58 O HETATM 1017 O HOH B1802 56.376 87.458 61.152 0.86 49.08 O HETATM 1018 O HOH B1804 54.429 65.685 64.316 0.93 44.38 O HETATM 1019 O HOH B1807 64.754 66.955 50.948 0.76 37.07 O HETATM 1020 O HOH B1808 60.659 74.906 65.433 0.92 38.17 O HETATM 1021 O HOH B1813 65.378 57.304 65.689 0.96 42.02 O ENDMDL MASTER 0 0 0 0 0 0 26 6 1020 1 0 15 END