1 74 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 GGCGCGUuAA CAAAGCGGuu AUGUAGCGGA PUGCAaAPCC GUCUAGUCCG GTPCGACUCC GGAACGCGCC UCCA 8 4SU 19 H2U 20 H2U 31 PSU 36 MIA 38 PSU 53 PSU LOOP1 52 58 LOOP2 13 21 LOOP3 30 38 Crystallography ? ? Angstroms 1 G P -2.433 -11.276 31.805 O3' -5.885 -12.159 34.987 2 G P -6.035 -10.676 35.587 O3' -7.473 -9.885 40.413 3 C P -7.639 -8.287 40.471 O3' -6.656 -6.010 45.091 4 G P -6.756 -4.426 44.858 O3' -3.671 -1.249 47.536 5 C P -3.791 0.290 47.089 O3' 0.188 3.602 47.260 6 G P -0.406 4.947 46.611 O3' 2.727 8.392 44.138 7 U P 1.724 9.581 43.737 O3' 2.343 12.635 39.348 8 u P 2.213 13.853 40.388 O3' 1.897 17.152 37.377 9 A P 3.308 17.887 37.144 O3' 5.047 22.206 34.165 10 A P 5.968 21.706 32.942 O3' 10.050 18.840 35.041 11 C P 9.231 17.905 36.057 O3' 11.330 16.895 40.923 12 A P 10.461 16.384 42.179 O3' 9.570 17.228 46.976 13 A P 8.330 16.334 47.488 O3' 4.430 17.648 50.490 14 A P 2.982 16.959 50.580 O3' -2.236 18.847 51.839 15 G P -3.358 17.712 51.668 O3' -7.952 20.152 52.620 16 C P -8.980 18.965 52.316 O3' -13.402 20.495 49.710 17 G P -14.320 19.330 49.088 O3' -15.934 22.111 44.852 18 G P -14.973 23.251 45.458 O3' -14.287 27.269 41.048 19 u P -12.809 27.826 40.793 O3' -10.912 32.204 43.449 20 u P -9.907 31.869 44.655 O3' -4.858 29.722 42.448 21 A P -4.332 28.299 42.971 O3' -1.668 30.499 46.292 22 U P -0.362 31.171 45.630 O3' 4.231 31.103 48.173 23 G P 5.383 31.690 47.217 O3' 10.290 29.888 48.478 24 U P 11.422 30.619 47.589 O3' 15.486 28.415 45.376 25 A P 16.246 29.656 44.691 O3' 19.362 28.550 39.846 26 G P 19.778 29.220 38.446 O3' 20.284 28.704 33.811 27 C P 20.613 30.266 33.642 O3' 18.890 32.973 29.627 28 G P 19.234 34.527 29.854 O3' 16.531 38.234 27.875 29 G P 17.423 39.489 28.315 O3' 14.897 43.791 29.404 30 A P 15.909 44.994 29.729 O3' 15.096 49.127 33.715 31 P P 16.445 49.978 33.559 O3' 19.033 50.764 37.965 32 U P 20.404 51.473 37.502 O3' 24.898 50.895 39.833 33 G P 25.386 52.133 38.925 O3' 27.081 49.734 34.636 34 C P 25.796 48.768 34.621 O3' 26.831 43.689 33.694 35 A P 25.739 42.601 34.149 O3' 25.268 39.068 38.656 36 a P 23.858 38.449 39.135 O3' 22.837 37.587 44.409 37 A P 21.230 37.438 44.417 O3' 18.569 38.477 48.204 38 P P 17.073 38.116 47.715 O3' 12.623 40.576 47.216 39 C P 11.483 39.790 46.403 O3' 7.529 41.770 42.660 40 C P 6.617 40.687 41.894 O3' 4.789 40.567 37.325 41 G P 4.247 39.050 37.337 O3' 4.366 36.494 32.869 42 U P 3.795 35.015 33.109 O3' 5.603 31.209 30.129 43 C P 4.353 30.225 30.368 O3' 6.647 24.924 30.030 44 U P 6.241 24.205 28.653 O3' 0.631 22.754 30.984 45 A P 0.095 24.066 31.748 O3' -2.127 20.510 33.769 46 G P -3.490 19.648 33.708 O3' -2.639 14.913 37.313 47 U P -2.467 13.353 36.959 O3' -2.105 13.827 31.908 48 C P -3.634 14.162 31.575 O3' -5.866 11.919 27.615 49 C P -7.376 12.462 27.630 O3' -11.283 9.730 25.876 50 G P -12.666 10.508 26.120 O3' -17.747 8.903 28.463 51 G P -18.774 10.000 29.023 O3' -22.340 9.081 32.520 52 T P -23.160 10.439 32.749 O3' -25.447 11.907 36.896 53 P P -26.131 13.116 36.088 O3' -26.132 17.827 37.906 54 C P -27.071 18.367 36.718 O3' -23.682 20.735 33.791 55 G P -22.547 19.608 33.962 O3' -17.552 20.959 34.847 56 A P -16.812 19.540 34.737 O3' -12.129 18.377 37.189 57 C P -11.008 19.395 36.663 O3' -9.450 15.185 38.846 58 U P -10.932 14.776 39.302 O3' -11.214 13.831 45.056 59 C P -11.433 12.285 45.456 O3' -15.072 8.824 45.218 60 C P -14.200 7.550 44.771 O3' -15.840 3.579 42.144 61 G P -14.499 2.724 41.920 O3' -14.265 0.395 37.706 62 G P -12.953 -0.471 37.362 O3' -10.060 -1.292 32.420 63 A P -8.570 -1.850 32.625 O3' -4.955 -0.592 29.115 64 A P -3.521 -1.214 29.479 O3' 1.000 0.698 28.390 65 C P 1.988 -0.433 28.960 O3' 6.455 0.890 31.328 66 G P 7.072 -0.420 32.026 O3' 9.721 -0.253 36.135 67 C P 10.012 -1.790 36.486 O3' 10.725 -3.018 41.276 68 G P 10.863 -4.581 41.595 O3' 8.683 -7.526 45.999 69 C P 8.939 -9.057 45.607 O3' 5.966 -12.396 48.012 70 C P 6.134 -13.885 47.440 O3' 2.298 -17.982 46.182 71 U P 2.933 -19.162 45.303 O3' 0.020 -21.192 41.849 72 C P 1.003 -22.284 41.208 O3' 0.753 -22.815 36.246 73 C P 1.129 -24.292 36.744 O3' 3.263 -27.310 33.481 74 A P 2.919 -28.780 32.945 O3' 0.497 -27.949 27.611 9 syn 56 syn 1 70 + + c 2 69 + + c 3 68 + + c 4 67 + + c 5 66 + + c 6 65 + + c 7 64 - - c 8 14 W H t 9 13 H W t 10 24 - - c 11 23 + + c 12 22 - - c 13 21 S H t 14 45 W W t 15 46 W W t 16 57 W W t 17 53 W S t 18 54 + + c 26 42 W W c 27 41 + + c 28 40 + + c 29 39 + + c 47 63 - - c 48 62 + + c 49 61 + + c 50 60 + + c 51 59 + + c 52 56 W H t 8 46 ! ! ! 9 14 ! ! ! 9 22 ! ! ! 10 23 ! ! ! 16 18 ! ! ! 8 45 ! ! ! 19 20 ! ! ! 32 35 ! ! ! 46 47 ! ! ! 49 50 ! ! ! 73 74 ! ! ! 1 70 7 47 63 5 10 24 3 26 42 4 SG1 8 9 SG2 13 21 SG3 25 25 SG4 30 38 SG5 43 46 SG6 52 58 SG7 71 74 1 77.209 63.895 2 77.209 90.518 3 77.209 117.141 4 77.209 143.765 5 77.209 170.388 6 77.209 197.011 7 77.209 223.634 8 93.183 223.634 9 109.156 223.634 10 318.770 420.753 11 292.180 419.418 12 265.591 418.084 13 244.140 433.813 14 217.771 437.311 15 192.961 427.719 16 175.803 407.393 17 170.511 381.324 18 178.386 355.917 19 197.493 337.410 20 223.139 330.350 21 249.025 336.471 22 268.793 354.269 23 295.383 355.603 24 321.973 356.938 25 322.773 340.984 26 375.152 359.606 27 401.741 360.941 28 428.331 362.275 29 454.921 363.610 30 476.372 347.880 31 502.741 344.382 32 527.551 353.974 33 544.709 374.301 34 550.000 400.369 35 542.125 425.777 36 523.019 444.283 37 497.373 451.343 38 471.486 445.222 39 451.718 427.425 40 425.128 426.090 41 398.539 424.756 42 371.949 423.421 43 141.104 276.880 44 125.130 276.880 45 109.156 276.880 46 93.183 276.880 47 77.209 276.880 48 77.209 303.503 49 77.209 330.126 50 77.209 356.749 51 77.209 383.372 52 90.522 407.050 53 88.272 434.121 54 71.232 455.277 55 45.261 463.241 56 19.291 455.277 57 2.250 434.121 58 0.000 407.050 59 13.313 383.372 60 13.313 356.749 61 13.313 330.126 62 13.313 303.503 63 13.313 276.880 64 13.313 223.634 65 13.313 197.011 66 13.313 170.388 67 13.313 143.765 68 13.313 117.141 69 13.313 90.518 70 13.313 63.895 71 13.313 47.922 72 13.313 31.948 73 13.313 15.974 74 13.313 0.000