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As of 9-Oct-2019 number of released structures: 10416
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Polymer Type: All + Protein Function: All + Structural Features: All + Experimental Method: All

Results: 7058  Download results as an excel file       Gallery view

NDB ID:

6FY6

PDB ID:

6FY6 

Release:

2019-10-09

Title:

Concerted dynamics of metallo-base pairs in an A/B-form helical transition (major species)

Classification:

DNA

Authors:

Schmidt, O.P., Jurt, S., Johannsen, S., Sigel, R.K.O., Luedtke, N.W.

Citation:

Dynamic structural polymorphism of a metallo DNA double helix (major species)
To Be Published pp. - 0

Experiment:

SOLUTION NMR

NDB ID:

6FY7

PDB ID:

6FY7 

Release:

2019-10-09

Title:

Concerted dynamics of metallo-base pairs in an A/B-form helical transition (minor species)

Classification:

DNA

Authors:

Schmidt, O.P., Jurt, S., Johannsen, S., Sigel, R.K.O., Luedtke, N.W.

Citation:

Dynamic structural polymorphism of a metallo DNA double helix (minor species)
To Be Published pp. - 0

Experiment:

SOLUTION NMR

NDB ID:

6RCN

PDB ID:

6RCN 

Release:

2019-10-09

Title:

Crystal structure of REXO2-D199A-dAdA

Classification:

HYDROLASE

Authors:

Nicholls, T.J., Spahr, H., Jiang, S., Siira, S.J., Koolmeister, C., Kauppila, J.H.K., Kaever, V., Rackham, O., Falkenberg, M., Filipovska, A., Larsson, N.G., Gustafsson, C.M.

Citation:

Dinucleotide degradation by REXO2 maintains promoter specificity in mammalian mitochondria
to be published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.25Å R work:0.211R free:0.246

NDB ID:

6RLS

PDB ID:

6RLS 

Release:

2019-10-09

Title:

Concerted dynamics of metallo-base pairs in an A/B-form helical transition (apo species)

Classification:

DNA

Authors:

Schmidt, O.P., Jurt, S., Johannsen, S., Karimi, A., Sigel, R.K.O., Luedtke, N.W.

Citation:

Dynamic isomerization of a metallated double helix (apo species)
To Be Published pp. - 0

Experiment:

SOLUTION NMR

NDB ID:

6FZS

PDB ID:

6FZS 

Release:

2019-10-02

Title:

Crystal structure of Smad5-MH1 bound to the GGCGC site.

Classification:

TRANSCRIPTION

Authors:

Ruiz, L., Kaczmarska, Z., Aragon, E., Cordero, J., Martin Malpartida, P., Freier, R., Marquez, J.A., Macias, M.J.

Citation:

Recognition of the 5GC DNA motif is conserved in BMP and TGF-beta activated Smad proteins
to be published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.31Å R work:0.193R free:0.24

NDB ID:

6FZT

PDB ID:

6FZT 

Release:

2019-10-02

Title:

Crystal structure of Smad8_9-MH1 bound to the GGCGC site.

Classification:

TRANSCRIPTION

Authors:

Ruiz, L., Kaczmarska, Z., Aragon, E., Cordero, J., Martin Malpartida, P., Freier, R., Marquez, J.A., Macias, M.J.

Citation:

Recognition of the 5GC DNA motif is conserved in BMP and TGF-beta activated Smad proteins
to be published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.46Å R work:0.193R free:0.237

NDB ID:

6JR0

PDB ID:

6JR0 

Release:

2019-10-02

Title:

Crystal structure of the human nucleosome phased with 12 selenium atoms

Classification:

GENE REGULATION/DNA

Authors:

Saotome, M., Horikoshi, N., Urano, K., Kujirai, T., Yuzurihara, H., Kurumizaka, H., Kagawa, W.

Citation:

Structure determination of the nucleosome core particle by selenium SAD phasing
Acta Crystallogr.,Sect.D 75 pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.5Å R work:0.221R free:0.253

NDB ID:

6JR1

PDB ID:

6JR1 

Release:

2019-10-02

Title:

Crystal structure of the human nucleosome phased with 16 selenium atoms

Classification:

GENE REGULATION/DNA

Authors:

Saotome, M., Horikoshi, N., Urano, K., Kujirai, T., Yuzurihara, H., Kurumizaka, H., Kagawa, W.

Citation:

Structure determination of the nucleosome core particle by selenium SAD phasing
Acta Crystallogr.,Sect.D 75 pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.4Å R work:0.208R free:0.242

NDB ID:

6U7T

PDB ID:

6U7T 

Release:

2019-10-02

Title:

MutY adenine glycosylase bound to DNA containing a transition state analog (1N) paired with d(8-oxo-G)

Classification:

hydrolase/DNA

Authors:

Woods, R.D., O'Shea, V.L., Chu, A., Cao, S., Richards, J.L., Horvath, M.P., David, S.S.

Citation:

Structure and stereochemistry of the base excision repair glycosylase MutY reveal a mechanism similar to retaining glycosidases.
Nucleic Acids Res. 44 pp.801 - 10 2016

Experiment:

X-RAY DIFFRACTION Resolution:2.0Å R work:0.261R free:0.27

NDB ID:

6JGW

PDB ID:

6JGW 

Release:

2019-09-25

Title:

Crystal structure of the transcriptional regulator CadR from P. putida in complex with DNA

Classification:

TRANSCRIPTION/DNA

Authors:

Liu, X., Hu, Q., Yang, J., Huang, S., Wei, T., Chen, W., He, Y., Wang, D., Liu, Z., Wang, K., Gan, J., Chen, H.

Citation:

Selective cadmium regulation mediated by a cooperative binding mechanism in CadR.
Proc.Natl.Acad.Sci.USA pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.8Å R work:0.204R free:0.253

NDB ID:

6JGX

PDB ID:

6JGX 

Release:

2019-09-25

Title:

Crystal structure of the transcriptional regulator CadR from P. putida in complex with Cadmium(II) and DNA

Classification:

TRANSCRIPTION/DNA

Authors:

Liu, X., Hu, Q., Yang, J., Huang, S., Wei, T., Chen, W., He, Y., Wang, D., Liu, Z., Wang, K., Gan, J., Chen, H.

Citation:

Selective cadmium regulation mediated by a cooperative binding mechanism in CadR.
Proc.Natl.Acad.Sci.USA pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.71Å R work:0.209R free:0.233

NDB ID:

6JNI

PDB ID:

6JNI 

Release:

2019-09-25

Title:

Crystal structure of the transcriptional regulator CadR from P. putida in complex with Zinc(II) and DNA

Classification:

TRANSCRIPTION/DNA

Authors:

Liu, X., Hu, Q., Yang, J., Huang, S., Wei, T., Chen, W., He, Y., Wang, D., Liu, Z., Wang, K., Gan, J., Chen, H.

Citation:

Selective cadmium regulation mediated by a cooperative binding mechanism in CadR.
Proc.Natl.Acad.Sci.USA pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.9Å R work:0.211R free:0.254

NDB ID:

6K3Z

PDB ID:

6K3Z 

Release:

2019-09-25

Title:

Crystal structure of dCas9 in complex with sgRNA and DNA (TGA PAM)

Classification:

HYDROLASE/DNA/RNA

Authors:

Chen, W., Zhang, H., Zhang, Y., Wang, Y., Gan, J., Ji, Q.

Citation:

Molecular basis for PAM recognition and high fidelity of an evolved Cas9 nuclease
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:3.2Å R work:0.196R free:0.275

NDB ID:

6K4P

PDB ID:

6K4P 

Release:

2019-09-25

Title:

Crystal structure of xCas9 in complex with sgRNA and DNA (TGG PAM)

Classification:

HYDROLASE/DNA/RNA

Authors:

Chen, W., Zhang, H., Zhang, Y., Wang, Y., Gan, J., Ji, Q.

Citation:

Molecular basis for PAM recognition and high fidelity of an evolved Cas9 nuclease
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.9Å R work:0.202R free:0.269

NDB ID:

6K4Q

PDB ID:

6K4Q 

Release:

2019-09-25

Title:

Crystal structure of xCas9 in complex with sgRNA and DNA (CGG PAM)

Classification:

HYDROLASE/DNA/RNA

Authors:

Chen, W., Zhang, H., Zhang, Y., Wang, Y., Gan, J., Ji, Q.

Citation:

Molecular basis for PAM recognition and high fidelity of an evolved Cas9 nuclease
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.7Å R work:0.203R free:0.275

NDB ID:

6K4S

PDB ID:

6K4S 

Release:

2019-09-25

Title:

Crystal structure of xCas9 in complex with sgRNA and DNA (TGC PAM)

Classification:

HYDROLASE/DNA/RNA

Authors:

Chen, W., Zhang, H., Zhang, Y., Wang, Y., Gan, J., Ji, Q.

Citation:

Molecular basis for PAM recognition and high fidelity of an evolved Cas9 nuclease
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:3.01Å R work:0.236R free:0.285

NDB ID:

6K4U

PDB ID:

6K4U 

Release:

2019-09-25

Title:

Crystal structure of xCas9 in complex with sgRNA and DNA (TGA PAM)

Classification:

HYDROLASE/DNA

Authors:

Chen, W., Zhang, H., Zhang, Y., Wang, Y., Gan, J., Ji, Q.

Citation:

Molecular basis for PAM recognition and high fidelity of an evolved Cas9 nuclease
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:3.2Å R work:0.219R free:0.282

NDB ID:

6K57

PDB ID:

6K57 

Release:

2019-09-25

Title:

Crystal structure of dCas9 in complex with sgRNA and DNA (CGA PAM)

Classification:

HYDROLASE/RNA/DNA

Authors:

Chen, W., Zhang, H., Zhang, Y., Wang, Y., Gan, J., Ji, Q.

Citation:

Molecular basis for PAM recognition and high fidelity of an evolved Cas9 nuclease
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.98Å R work:0.197R free:0.274

NDB ID:

6S16

PDB ID:

6S16 

Release:

2019-09-25

Title:

T. thermophilus RuvC in complex with Holliday junction substrate

Classification:

HYDROLASE

Authors:

Gorecka, K.M., Krepl, M., Szlachcic, A., Poznanski, J., Sponer, J., Nowotny, M.

Citation:

RuvC uses dynamic probing of the Holliday junction to achieve sequence specificity and efficient resolution.
Nat Commun 10 pp.4102 - 4102 2019

Experiment:

X-RAY DIFFRACTION Resolution:3.409Å R work:0.181R free:0.23

NDB ID:

6SEI

PDB ID:

6SEI 

Release:

2019-09-25

Title:

Recognition and processing of branched DNA substrates by Slx1-Slx4 nuclease

Classification:

DNA BINDING PROTEIN

Authors:

Gaur, V., Ziajko, W., Nirwal, S., Szlachcic, A., Gapinska, M., Nowotny, M.

Citation:

Recognition and processing of branched DNA substrates by Slx1-Slx4 nuclease
Nucleic Acids Res. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.69Å R work:0.208R free:0.265

NDB ID:

6H3R

PDB ID:

6H3R 

Release:

2019-09-18

Title:

Crystal structure of Smad2 without exon -MH1 bound to the CAGAC site.

Classification:

TRANSCRIPTION

Authors:

Ruiz, L., Kaczmarska, Z., Aragon, E., Gomes, T., Martin Malpartida, P., de Martin Garrido, N., Freier, R., Marquez, J.A., Macias, M.J.

Citation:

Recognition of 5GC DNA motifs is conserved in BMP and TGF-beta activated Smads
to be published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.75Å R work:0.201R free:0.222

NDB ID:

6GN2

PDB ID:

6GN2 

Release:

2019-09-11

Title:

Racemic crystal structure of A-DNA duplex formed from d(CCCGGG) in space group R3

Classification:

DNA

Authors:

Mandal, P.K., Collie, G.W., Kauffmann, B., Huc, I.

Citation:

Racemic crystal structures of A-DNA duplexes
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.48Å R work:0.258R free:0.272

NDB ID:

6GN3

PDB ID:

6GN3 

Release:

2019-09-11

Title:

Racemic crystal structure of A-DNA duplex formed from d(CCCGGG) in space group P21/n

Classification:

DNA

Authors:

Mandal, P.K., Collie, G.W., Kauffmann, B., Huc, I.

Citation:

Racemic crystal structures of A-DNA duplexes
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.8Å R work:0.279R free:0.318

NDB ID:

6IDO

PDB ID:

6IDO 

Release:

2019-09-11

Title:

Crystal structure of Klebsiella pneumoniae sigma4 of sigmaS fusing with the RNA polymerase beta-flap-tip-helix in complex with -35 element DNA

Classification:

TRANSCRIPTION

Authors:

Lou, Y.C., Chou, C.C., Yeh, H.H., Chien, C.Y., Sadotra, S., Hsu, C.H., Chen, C.

Citation:

Constructing well-folded sigma4 domains from bacterial sigma70 and sigmaS factors for -35 element DNA recognition and transcription factor interaction
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:3.748Å R work:0.222R free:0.252

NDB ID:

6KI6

PDB ID:

6KI6 

Release:

2019-09-11

Title:

Crystal structure of BCL11A in complex with gamma-globin -115 HPFH region

Classification:

TRANSCRIPTION/DNA

Authors:

Yang, Y., Xu, Z., He, C., Zhang, B., Shi, Y., Li, F.

Citation:

Structural insights into the recognition of gamma-globin gene promoter by BCL11A.
Cell Res. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.5Å R work:0.206R free:0.251

NDB ID:

6OZF

PDB ID:

6OZF 

Release:

2019-09-04

Title:

Crystal structure of Thermotoga maritima (Tm) Endonuclease V (D110N) in complex with a 12mer DNA containing an inosine followed by a ribo-adenosine

Classification:

HYDROLASE

Authors:

Wu, J., Samara, N.L., Kuraoka, I., Yang, W.

Citation:

Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.8Å R work:0.166R free:0.197

NDB ID:

6OZG

PDB ID:

6OZG 

Release:

2019-09-04

Title:

Crystal structure of Thermotoga maritima (Tm) Endonuclease V (E89Q) in complex with a 12mer DNA containing an inosine followed by a ribo-adenosine

Classification:

HYDROLASE

Authors:

Wu, J., Samara, N.L., Kuraoka, I., Yang, W.

Citation:

Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.93Å R work:0.177R free:0.209

NDB ID:

6OZH

PDB ID:

6OZH 

Release:

2019-09-04

Title:

Crystal structure of Ciona intestinalis (Ci) Endonuclease V in complex with a 24mer DNA containing an inosine followed by a ribo-adenosine

Classification:

HYDROLASE

Authors:

Wu, J., Samara, N.L., Kuraoka, I., Yang, W.

Citation:

Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:3.026Å R work:0.233R free:0.269

NDB ID:

6OZI

PDB ID:

6OZI 

Release:

2019-09-04

Title:

Crystal structure of Ciona intestinalis (Ci) Endonuclease V (D234N) in complex with a 23mer DNA containing an inosine followed by a ribo-adenosine

Classification:

HYDROLASE

Authors:

Wu, J., Samara, N.L., Kuraoka, I., Yang, W.

Citation:

Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.302Å R work:0.174R free:0.201

NDB ID:

6OZJ

PDB ID:

6OZJ 

Release:

2019-09-04

Title:

Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine in the absence of divalent cation

Classification:

HYDROLASE

Authors:

Wu, J., Samara, N.L., Kuraoka, I., Yang, W.

Citation:

Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.247Å R work:0.156R free:0.193

NDB ID:

6OZK

PDB ID:

6OZK 

Release:

2019-09-04

Title:

Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after 68h soak in Ca2+

Classification:

HYDROLASE

Authors:

Wu, J., Samara, N.L., Kuraoka, I., Yang, W.

Citation:

Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.104Å R work:0.176R free:0.214

NDB ID:

6OZL

PDB ID:

6OZL 

Release:

2019-09-04

Title:

Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 2 min soak in Mn2+

Classification:

HYDROLASE

Authors:

Wu, J., Samara, N.L., Kuraoka, I., Yang, W.

Citation:

Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.1Å R work:0.175R free:0.216

NDB ID:

6OZM

PDB ID:

6OZM 

Release:

2019-09-04

Title:

Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 10 min soak in 10 mM Mn2+

Classification:

HYDROLASE/RNA

Authors:

Wu, J., Samara, N.L., Kuraoka, I., Yang, W.

Citation:

Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.15Å R work:0.173R free:0.216

NDB ID:

6OZN

PDB ID:

6OZN 

Release:

2019-09-04

Title:

Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 15 min soak in 10 mM Mn2+

Classification:

HYDROLASE/RNA

Authors:

Wu, J., Samara, N.L., Kuraoka, I., Yang, W.

Citation:

Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.9Å R work:0.191R free:0.221

NDB ID:

6OZO

PDB ID:

6OZO 

Release:

2019-09-04

Title:

Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 30 min soak in 10 mM Mn2+

Classification:

HYDROLASE/RNA

Authors:

Wu, J., Samara, N.L., Kuraoka, I., Yang, W.

Citation:

Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.235Å R work:0.168R free:0.211

NDB ID:

6OZP

PDB ID:

6OZP 

Release:

2019-09-04

Title:

Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 180 min soak in 10 mM Mn2+

Classification:

HYDROLASE/RNA

Authors:

Wu, J., Samara, N.L., Kuraoka, I., Yang, W.

Citation:

Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.96Å R work:0.174R free:0.201

NDB ID:

6OZQ

PDB ID:

6OZQ 

Release:

2019-09-04

Title:

Crystal structure of Mus musculus (Mm) Endonuclease V (K155M) in complex with a 23mer RNA oligo containing an inosine after a 100 min soak in 10 mM Mn2+ and K+

Classification:

HYDROLASE

Authors:

Wu, J., Samara, N.L., Kuraoka, I., Yang, W.

Citation:

Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.153Å R work:0.173R free:0.209

NDB ID:

6OZR

PDB ID:

6OZR 

Release:

2019-09-04

Title:

Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 15 min soak in 10 mM Mg2+

Classification:

HYDROLASE

Authors:

Wu, J., Samara, N.L., Kuraoka, I., Yang, W.

Citation:

Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.15Å R work:0.157R free:0.194

NDB ID:

6OZS

PDB ID:

6OZS 

Release:

2019-09-04

Title:

Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 90 min soak in 10 mM Mg2+

Classification:

HYDROLASE/RNA

Authors:

Wu, J., Samara, N.L., Kuraoka, I., Yang, W.

Citation:

Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.41Å R work:0.19R free:0.236

NDB ID:

6P1M

PDB ID:

6P1M 

Release:

2019-09-04

Title:

Binary complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG

Classification:

TRANSFERASE

Authors:

Kaminski, A.M., Chiruvella, K.K., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Unexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2'-guanosine.
Nucleic Acids Res. 47 pp.9410 - 9422 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.65Å R work:0.165R free:0.189

NDB ID:

6P1N

PDB ID:

6P1N 

Release:

2019-09-04

Title:

Pre-catalytic ternary complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and bound incoming dAMPNPP

Classification:

TRANSFERASE

Authors:

Kaminski, A.M., Chiruvella, K.K., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Unexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2'-guanosine.
Nucleic Acids Res. 47 pp.9410 - 9422 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.6Å R work:0.165R free:0.186

NDB ID:

6P1O

PDB ID:

6P1O 

Release:

2019-09-04

Title:

Post-catalytic nicked complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and newly incorporated dAMP

Classification:

TRANSFERASE

Authors:

Kaminski, A.M., Chiruvella, K.K., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Unexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2'-guanosine.
Nucleic Acids Res. 47 pp.9410 - 9422 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.65Å R work:0.167R free:0.187

NDB ID:

6P1P

PDB ID:

6P1P 

Release:

2019-09-04

Title:

Pre-catalytic ternary complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and bound incoming dCMPNPP

Classification:

TRANSFERASE

Authors:

Kaminski, A.M., Chiruvella, K.K., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Unexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2'-guanosine.
Nucleic Acids Res. 47 pp.9410 - 9422 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.75Å R work:0.164R free:0.184

NDB ID:

6P1Q

PDB ID:

6P1Q 

Release:

2019-09-04

Title:

Post-catalytic nicked complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and newly incorporated dCMP

Classification:

TRANSFERASE

Authors:

Kaminski, A.M., Chiruvella, K.K., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Unexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2'-guanosine.
Nucleic Acids Res. 47 pp.9410 - 9422 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.9Å R work:0.168R free:0.206

NDB ID:

6P1R

PDB ID:

6P1R 

Release:

2019-09-04

Title:

Pre-catalytic ternary complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and bound incoming AMPNPP

Classification:

TRANSFERASE

Authors:

Kaminski, A.M., Chiruvella, K.K., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Unexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2'-guanosine.
Nucleic Acids Res. 47 pp.9410 - 9422 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.701Å R work:0.174R free:0.194

NDB ID:

6P1S

PDB ID:

6P1S 

Release:

2019-09-04

Title:

Post-catalytic nicked complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and newly incorporated AMP

Classification:

TRANSFERASE/DNA

Authors:

Kaminski, A.M., Chiruvella, K.K., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Unexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2'-guanosine.
Nucleic Acids Res. 47 pp.9410 - 9422 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.75Å R work:0.172R free:0.195

NDB ID:

6P1T

PDB ID:

6P1T 

Release:

2019-09-04

Title:

Pre-catalytic ternary complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and bound CMPCPP

Classification:

TRANSFERASE

Authors:

Kaminski, A.M., Chiruvella, K.K., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Unexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2'-guanosine.
Nucleic Acids Res. 47 pp.9410 - 9422 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.7Å R work:0.169R free:0.19

NDB ID:

6P1U

PDB ID:

6P1U 

Release:

2019-09-04

Title:

Post-catalytic nicked complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and newly incorporated CMP

Classification:

TRANSFERASE

Authors:

Kaminski, A.M., Chiruvella, K.K., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Unexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2'-guanosine.
Nucleic Acids Res. 47 pp.9410 - 9422 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.75Å R work:0.169R free:0.192

NDB ID:

6P1V

PDB ID:

6P1V 

Release:

2019-09-04

Title:

Pre-catalytic ternary complex of human DNA Polymerase Mu with 1-nt gapped substrate containing undamaged template dG and bound incoming dCMPNPP

Classification:

TRANSFERASE

Authors:

Kaminski, A.M., Chiruvella, K.K., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Unexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2'-guanosine.
Nucleic Acids Res. 47 pp.9410 - 9422 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.95Å R work:0.176R free:0.203

NDB ID:

6P1W

PDB ID:

6P1W 

Release:

2019-09-04

Title:

Pre-catalytic ternary complex of human DNA Polymerase Mu with 1-nt gapped substrate containing undamaged template dG and bound incoming CMPCPP

Classification:

TRANSFERASE

Authors:

Kaminski, A.M., Chiruvella, K.K., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Unexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2'-guanosine.
Nucleic Acids Res. 47 pp.9410 - 9422 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.751Å R work:0.163R free:0.189