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As of 24-Apr-2019 number of released structures: 10153
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Polymer Type: All + Protein Function: All + Structural Features: All + Experimental Method: All

Results: 6880  Download results as an excel file       Gallery view

NDB ID:

6G8S

PDB ID:

6G8S 

Release:

2019-04-24

Title:

[Ru(TAP)2(11,12-CN2-dppz)]2+ bound to d(CCGGACCCGG/CCGGGTCCGG)2

Classification:

DNA

Authors:

McQuaid, K.T., Hall, J.P., Cardin, C.J.

Citation:

[Ru(TAP)2(11,12-CN2-dppz)]2+ bound to d(CCGGACCCGG/CCGGGTCCGG)2
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.66Å R work:0.187R free:0.203

NDB ID:

6GZ6

PDB ID:

6GZ6 

Release:

2019-04-24

Title:

Structure of a left-handed G-quadruplex

Classification:

DNA

Authors:

Bakalar, B., Heddi, B., Schmitt, E., Mechulam, Y., Phan, A.T.

Citation:

A Minimal Sequence for Left-Handed G-Quadruplex Formation.
Angew.Chem.Int.Ed.Engl. 58 pp.2331 - 2335 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.006Å R work:0.184R free:0.23

NDB ID:

6H1V

PDB ID:

6H1V 

Release:

2019-04-24

Title:

The crystal structure of Pol2CORE in complex with DNA and an incoming nucleotide, carrying an Fe-S cluster

Classification:

DNA BINDING PROTEIN

Authors:

Ter Beek, J., Parkash, V., Bylund, G.O., Osterman, P., Sauer-Eriksson, A.E., Johansson, E.

Citation:

Structural evidence for an essential Fe-S cluster in the catalytic core domain of DNA polymerase ε.
Nucleic Acids Res. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.7Å R work:0.238R free:0.265

NDB ID:

6IIQ

PDB ID:

6IIQ 

Release:

2019-04-24

Title:

Complex structure of the HRP3 PWWP domain with a 16-bp TA-rich DNA

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Wang, Z., Tian, W.

Citation:

Complex structure of the HRP3 PWWP domain with a 16-bp TA-rich DNA
Nucleic Acids Res. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.85Å R work:0.204R free:0.253

NDB ID:

6IIR

PDB ID:

6IIR 

Release:

2019-04-24

Title:

Complex structure of the HRP3 PWWP domain with a 10-bp GC-rich DNA

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Wang, Z., Tian, W.

Citation:

Complex structure of the HRP3 PWWP domain with a 10-bp GC-rich DNA
Nucleic Acids Res. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.2Å R work:0.202R free:0.257

NDB ID:

6IIS

PDB ID:

6IIS 

Release:

2019-04-24

Title:

Complex structure of the HRP3 PWWP domain with both a 16-bp TA-rich DNA and an H3K36me3-containing histone peptide

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Wang, Z., Tian, W.

Citation:

Complex structure of the HRP3 PWWP domain with both a 16-bp TA-rich DNA and an H3K36me3-containing histone peptide
Nucleic Acids Res. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.358Å R work:0.185R free:0.263

NDB ID:

6IIT

PDB ID:

6IIT 

Release:

2019-04-24

Title:

Complex structure of the HRP3 PWWP domain with both a 16-bp TA-rich DNA and an H3K36me2-containing histone peptide

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Wang, Z., Tian, W.

Citation:

Complex structure of the HRP3 PWWP domain with both a 16-bp TA-rich DNA and a H3K36me2-containing histone peptide
Nucleic Acids Res. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.1Å R work:0.19R free:0.264

NDB ID:

6J4R

PDB ID:

6J4R 

Release:

2019-04-24

Title:

Structural basis for the target DNA recognition and binding by the MYB domain of phosphate starvation response regulator 1

Classification:

TRANSCRIPTION/DNA

Authors:

Jiang, M., Sun, L., Isupov, M.N., Littlechild, J.A., Wu, X., Wang, Q., Wang, Q., Yang, W., Wu, Y.

Citation:

Structural Basis for the Target DNA Recognition and Binding by the MYB Domain of Phosphate Starvation Response 1.
FEBS J. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.8Å R work:0.215R free:0.249

NDB ID:

6J5B

PDB ID:

6J5B 

Release:

2019-04-24

Title:

Structural basis for the target DNA recognition and binding by the MYB domain of phosphate starvation response regulator 1

Classification:

TRANSCRIPTION/DNA

Authors:

Jiang, M., Sun, L., Isupov, M.N., Littlechild, J.A., Wu, X., Wang, Q., Wang, Q., Yang, W., Wu, Y.

Citation:

Structural Basis for the Target DNA Recognition and Binding by the MYB Domain of Phosphate Starvation Response 1.
FEBS J. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.7Å R work:0.217R free:0.25

NDB ID:

6O19

PDB ID:

6O19 

Release:

2019-04-24

Title:

Crystal Structure of Pho7 complex with pho1 promoter site 2

Classification:

TRANSCRIPTION/DNA

Authors:

Garg, A., Goldgur, Y., Sanchez, A., Schwer, B., Shuman, S.

Citation:

Structure of fission yeast transcription factor Pho7 bound to pho1 promoter DNA and effect of Pho7 mutations on DNA binding and phosphate homeostasis
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.596Å R work:0.18R free:0.202

NDB ID:

6OE7

PDB ID:

6OE7 

Release:

2019-04-24

Title:

Crystal structure of HMCES cross-linked to DNA abasic site

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Halabelian, L., Li, Y., Zeng, H., Bountra, C., Edwards, A.M., Arrowsmith, C.H.

Citation:

Crystal structure of HMCES cross-linked to DNA abasic site
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.2Å R work:0.194R free:0.216

NDB ID:

6QZK

PDB ID:

6QZK 

Release:

2019-04-24

Title:

Structure of Clostridium butyricum Argonaute bound to a guide DNA (5' deoxycytidine) and a 19-mer target DNA

Classification:

HYDROLASE

Authors:

Hegge, J.W., Swarts, D.C., Chandradoss, S.D., Cui, T.J., Kneppers, J., Jinek, M., Joo, C., Van der Oost, J.

Citation:

DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:3.548Å R work:0.247R free:0.275

NDB ID:

6JOO

PDB ID:

6JOO 

Release:

2019-04-17

Title:

Crystal structure of Corynebacterium diphtheriae Cas9 in complex with sgRNA and target DNA

Classification:

HYDROLASE/DNA/RNA

Authors:

Nureki, O., Hatada, I., Horii, T., Ishitani, R., Zhang, F., Nishimasu, H., Gootenberg, J., Hirano, S., Abudayyeh, O.

Citation:

Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9
Nat Commun pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.9Å R work:0.22R free:0.253

NDB ID:

6QIB

PDB ID:

6QIB 

Release:

2019-04-17

Title:

The crystal structure of Pol2CORE in complex with DNA and an incoming nucleotide, carrying an Fe-S cluster

Classification:

DNA BINDING PROTEIN

Authors:

Ter Beek, J., Parkash, V., Bylund, G.O., Osterman, P., Sauer-Eriksson, A.E., Johansson, E.

Citation:

Structural evidence for an essential Fe-S cluster in the catalytic core domain of DNA polymerase ε.
Nucleic Acids Res. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.8Å R work:0.223R free:0.285

NDB ID:

6QX1

PDB ID:

6QX1 

Release:

2019-04-17

Title:

2.7A structure of benzoisoxazole 3 with S.aureus DNA gyrase and DNA.

Classification:

ISOMERASE

Authors:

Thalji, R.K., Raha, K., Andreotti, D., Checchia, A., Cui, H., Meneghelli, G., Profeta, R., Tonelli, F., Tommasi, S., Bakshi, T., Donovan, B.T., Howells, A., Jain, S., Nixon, C., Quinque, G., McCloskey, L., Bax, B.D., Neu, M., Chan, P.F., Stavenger, R.A.

Citation:

Structure-guided design of antibacterials that allosterically inhibit DNA gyrase.
Bioorg.Med.Chem.Lett. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.65Å R work:0.162R free:0.206

NDB ID:

6QX2

PDB ID:

6QX2 

Release:

2019-04-17

Title:

3.4A structure of benzoisoxazole 3 with S.aureus DNA gyrase and DNA

Classification:

ISOMERASE

Authors:

Thalji, R.K., Raha, K., Andreotti, D., Checchia, A., Cui, H., Meneghelli, G., Profeta, R., Tonelli, F., Tommasi, S., Bakshi, T., Donovan, B.T., Howells, A., Jain, S., Nixon, C., Quinque, G., McCloskey, L., Bax, B.D., Neu, M., Chan, P.F., Stavenger, R.A.

Citation:

Structure-guided design of antibacterials that allosterically inhibit DNA gyrase.
Bioorg.Med.Chem.Lett. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:3.4Å R work:0.176R free:0.208

NDB ID:

5ZMD

PDB ID:

5ZMD 

Release:

2019-04-10

Title:

Crystal structure of FTO in complex with m6dA modified ssDNA

Classification:

OXIDOREDUCTASE/DNA

Authors:

Zhang, X., Wei, L.H., Wang, Y., Xiao, Y., Liu, J., Zhang, W., Yan, N., Amu, G., Tang, X., Zhang, L., Jia, G.

Citation:

Structural insights into FTO's catalytic mechanism for the demethylation of multiple RNA substrates.
Proc. Natl. Acad. Sci. U.S.A. 116 pp.2919 - 2924 2019

Experiment:

X-RAY DIFFRACTION Resolution:3.3Å R work:0.27R free:0.291

NDB ID:

6FC9

PDB ID:

6FC9 

Release:

2019-04-10

Title:

The 1,8-bis(aminomethyl)anthracene and Quadruplex-duplex junction complex

Classification:

DNA

Authors:

Santana, A., Serrano, I., Montalvillo-Jimenez, L., Corzana, F., Bastida, A., Jimenez-Barbero, J., Gonzalez, C., Asensio, J.L.

Citation:

Minimalistic scaffolds for the selective recognition of Quad-ruplex-Duplex Junctions: Targeting the G4 Hot-Spot
To Be Published pp. - 0

Experiment:

SOLUTION NMR

NDB ID:

6G3B

PDB ID:

6G3B 

Release:

2019-04-10

Title:

AvaII restriction endonuclease in complex with an RNA/DNA hybrid

Classification:

HYDROLASE

Authors:

Kisiala, M., Kowalska, M., Czapinska, H., Bochtler, M.

Citation:

Restriction endonucleases that cleave RNA/DNA heteroduplexes bind dsDNA in A-like conformation
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.8Å R work:0.167R free:0.202

NDB ID:

6MDX

PDB ID:

6MDX 

Release:

2019-04-10

Title:

Mechanism of protease dependent DPC repair

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Li, F., Raczynska, J.E., Chen, Z., Yu, H.

Citation:

Structural Insight into DNA-Dependent Activation of Human Metalloprotease Spartan.
Cell Rep 26 pp.3336 - 3346.e4 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.55Å R work:0.159R free:0.192

NDB ID:

6OEA

PDB ID:

6OEA 

Release:

2019-04-10

Title:

Crystal structure of HMCES SRAP domain in complex with longer 3' overhang DNA

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Halabelian, L., Ravichandran, M., Li, Y., Zeng, H., Bountra, C., Edwards, A.M., Arrowsmith, C.H.

Citation:

Crystal structure of HMCES SRAP domain in complex with longer 3' overhang DNA
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.1Å R work:0.208R free:0.241

NDB ID:

6OEB

PDB ID:

6OEB 

Release:

2019-04-10

Title:

Crystal structure of HMCES SRAP domain in complex with 3' overhang DNA

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Halabelian, L., Ravichandran, M., Li, Y., Zeng, H., Bountra, C., Edwards, A.M., Arrowsmith, C.H.

Citation:

Crystal structure of HMCES SRAP domain in complex with 3' overhang DNA
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.1Å R work:0.205R free:0.235

NDB ID:

5ZGN

PDB ID:

5ZGN 

Release:

2019-04-03

Title:

The crystal structure of KacTA-DNA complex

Classification:

TOXIN

Authors:

Qian, H.L., Yao, Q.Q., Gan, J.H., Ou, H.Y.

Citation:

The crystal structure of KacTA-DNA complex
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.24Å R work:0.214R free:0.254

NDB ID:

5ZKI

PDB ID:

5ZKI 

Release:

2019-04-03

Title:

Human EXOG-H140A in complex with duplex DNA

Classification:

HYDROLASE/DNA

Authors:

Wu, C.C., Lin, J.L.J., Yang-Yen, H.F., Yuan, H.S.

Citation:

A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication.
Nucleic Acids Res. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.321Å R work:0.179R free:0.218

NDB ID:

5ZKJ

PDB ID:

5ZKJ 

Release:

2019-04-03

Title:

Human EXOG-H140A in complex with RNA/DNA hybrid duplex

Classification:

HYDROLASE/RNA/DNA

Authors:

Wu, C.C., Lin, J.L.J., Yang-Yen, H.F., Yuan, H.S.

Citation:

A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication.
Nucleic Acids Res. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.798Å R work:0.18R free:0.226

NDB ID:

6E3R

PDB ID:

6E3R 

Release:

2019-04-03

Title:

Structure of human DNA polymerase beta complexed with 8OA as the template base in a 1-nucleotide gapped DNA

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Koag, M.C., Jung, H., Lee, S.

Citation:

Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases.
J. Am. Chem. Soc. 141 pp.4584 - 4596 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.26Å R work:0.203R free:0.272

NDB ID:

6E3V

PDB ID:

6E3V 

Release:

2019-04-03

Title:

Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable TTP

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Koag, M.C., Jung, H., Lee, S.

Citation:

Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases.
J. Am. Chem. Soc. 141 pp.4584 - 4596 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.96Å R work:0.194R free:0.239

NDB ID:

6E3W

PDB ID:

6E3W 

Release:

2019-04-03

Title:

Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable GTP

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Koag, M.C., Jung, H., Lee, S.

Citation:

Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases.
J. Am. Chem. Soc. 141 pp.4584 - 4596 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.02Å R work:0.193R free:0.245

NDB ID:

6E3X

PDB ID:

6E3X 

Release:

2019-04-03

Title:

Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable ATP

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Koag, M.-C., Lee, S.

Citation:

Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable ATP
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.65Å R work:0.192R free:0.266

NDB ID:

6IID

PDB ID:

6IID 

Release:

2019-04-03

Title:

Human EXOG-H140A in complex with RNA-DNA chimeric duplex

Classification:

HYDROLASE/DNA

Authors:

Wu, C.C., Lin, J.L.J., Yang-Yen, H.F., Yuan, H.S.

Citation:

A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication.
Nucleic Acids Res. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.986Å R work:0.199R free:0.252

NDB ID:

6JKN

PDB ID:

6JKN 

Release:

2019-04-03

Title:

Crystal Structure of G-quadruplex Formed by Bromo-substituted Human Telomeric DNA

Classification:

DNA

Authors:

Geng, Y., Liu, C., Zhou, B., Cai, Q., Miao, H., Shi, X., Xu, N., You, Y., Fung, C.P., Din, R.U., Zhu, G.

Citation:

The crystal structure of an antiparallel chair-type G-quadruplex formed by Bromo-substituted human telomeric DNA.
Nucleic Acids Res. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.401Å R work:0.158R free:0.184

NDB ID:

6N2R

PDB ID:

6N2R 

Release:

2019-04-03

Title:

Binary complex crystal structure of DNA polymerase Beta with 5-carboxy-dC (5-caC) at the templating position

Classification:

gene regulation/dna

Authors:

Howard, M.J., Foley, K.G., Shock, D.D., Batra, V.K., Wilson, S.H.

Citation:

Molecular basis for the faithful replication of 5-methylcytosine and its oxidized forms by DNA Polymerase ß.
J. Biol. Chem. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.1Å R work:0.209R free:0.266

NDB ID:

5ZG9

PDB ID:

5ZG9 

Release:

2019-03-27

Title:

Crystal structure of MoSub1-ssDNA complex in phosphate buffer

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Zhao, Y., Zhang, Y., Huang, J., Wang, S., Yi, L., Zhang, X., Xu, M., Fang, X., Liu, J.

Citation:

The effect of phosphate ion on the ssDNA binding mode of MoSub1, a Sub1/PC4 homolog from rice blast fungus.
Proteins 87 pp.257 - 264 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.04Å R work:0.176R free:0.224

NDB ID:

5ZKL

PDB ID:

5ZKL 

Release:

2019-03-27

Title:

Crystal structure of Streptococcus pneumoniae SP_0782 (residues 7-79) in complex with single-stranded DNA dT12

Classification:

UNKNOWN FUNCTION/DNA

Authors:

Lu, G., Li, S., Zhu, J., Yang, Y., Gong, P.

Citation:

Crystal structure of Streptococcus pneumoniae SP_0782 (residues 7-79) in complex with single-stranded DNA dT12
To be published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.951Å R work:0.181R free:0.209

NDB ID:

5ZKM

PDB ID:

5ZKM 

Release:

2019-03-27

Title:

Crystal structure of Streptococcus pneumoniae SP_0782 (residues 7-79) in complex with single-stranded DNA TCTTCC

Classification:

UNKNOWN FUNCTION/DNA

Authors:

Lu, G., Li, S., Zhu, J., Yang, Y., Gong, P.

Citation:

Crystal structure of Streptococcus pneumoniae SP_0782 (residues 7-79) in complex with single-stranded DNA TCTTCC
To be published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.65Å R work:0.178R free:0.203

NDB ID:

6ADV

PDB ID:

6ADV 

Release:

2019-03-27

Title:

Crystal Structure Analysis of the duplex containing the S2T(2',4'-BNA/LNA)G mismatch pairs

Classification:

DNA

Authors:

Habuchi, T., Yamaguchi, T., Aoyama, H., Horiba, M., Ito, K.R., Obika, S.

Citation:

Hybridization and Mismatch Discrimination Abilities of 2',4'-Bridged Nucleic Acids Bearing 2-Thiothymine or 2-Selenothymine Nucleobase.
J. Org. Chem. 84 pp.1430 - 1439 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.96Å R work:0.253R free:0.296

NDB ID:

6AEB

PDB ID:

6AEB 

Release:

2019-03-27

Title:

Crystal structure of xCas9 in complex with sgRNA and target DNA (AAG PAM)

Classification:

DNA BINDING PROTEIN/RNA

Authors:

Guo, M., Ren, K., Zhu, Y., Tang, Z., Wang, Y., Zhang, B., Huang, Z.

Citation:

Structural insights into a high fidelity variant of SpCas9.
Cell Res. 29 pp.183 - 192 2019

Experiment:

X-RAY DIFFRACTION Resolution:3.004Å R work:0.231R free:0.282

NDB ID:

6AEG

PDB ID:

6AEG 

Release:

2019-03-27

Title:

Crystal structure of xCas9 in complex with sgRNA and target DNA (GAT PAM)

Classification:

DNA BINDING PROTEIN/DNA/RNA

Authors:

Guo, M., Ren, K., Zhu, Y., Tang, Z., Wang, Y., Zhang, B., Huang, Z.

Citation:

Structural insights into a high fidelity variant of SpCas9.
Cell Res. 29 pp.183 - 192 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.701Å R work:0.214R free:0.262

NDB ID:

6CU9

PDB ID:

6CU9 

Release:

2019-03-27

Title:

Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable CTP and MANGANESE

Classification:

Transferase, Lyase/DNA

Authors:

Koag, M.-C., Lee, S.

Citation:

Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable CTP and MANGANESE
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.04Å R work:0.193R free:0.24

NDB ID:

6CUA

PDB ID:

6CUA 

Release:

2019-03-27

Title:

Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable GTP and MANGANESE

Classification:

Transferase, Lyase/DNA

Authors:

Koag, M.-C., Lee, S.

Citation:

Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable GTP and MANGANESE
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.17Å R work:0.209R free:0.259

NDB ID:

6CUB

PDB ID:

6CUB 

Release:

2019-03-27

Title:

Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable ATP and MANGANESE

Classification:

Transferase, Lyase/DNA

Authors:

Koag, M.-C., Lee, S.

Citation:

Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable ATP and MANGANESE
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.05Å R work:0.196R free:0.254

NDB ID:

6E53

PDB ID:

6E53 

Release:

2019-03-27

Title:

Structure of TERT in complex with a novel telomerase inhibitor

Classification:

TRANSFERASE/TRANSFERASE INHIBITOR

Authors:

Hernandez-Sanchez, W., Huang, W., Plucinsky, B., Garcia-Vazquez, N., Berdis, A.J., Skordalakes, E., Taylor, D.J.

Citation:

Structure of TERT in complex with a novel telomerase inhibitor
To be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.8Å R work:0.23R free:0.287

NDB ID:

6JNL

PDB ID:

6JNL 

Release:

2019-03-27

Title:

REF6 ZnF2-4-NAC004 complex

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Yao, Q.Q., Wu, B.X., Ma, J.B.

Citation:

REF6 ZnF2-4-NAC004 complex
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.15Å R work:0.204R free:0.249

NDB ID:

6JNM

PDB ID:

6JNM 

Release:

2019-03-27

Title:

REF6 ZnF2-4-NAC004-mC3 complex

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Yao, Q.Q., Wu, B.X., Ma, J.B.

Citation:

REF6 ZnF2-4-NAC004-mC3 complex
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.05Å R work:0.2R free:0.228

NDB ID:

6JNN

PDB ID:

6JNN 

Release:

2019-03-27

Title:

REF6 ZnF2-4-NAC004-mC1 complex

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Yao, Q.Q., Wu, B.X., Ma, J.B.

Citation:

REF6 ZnF2-4-NAC004-mC1 complex
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.6Å R work:0.25R free:0.264

NDB ID:

6N2S

PDB ID:

6N2S 

Release:

2019-03-27

Title:

Ternary complex crystal structure of DNA polymerase Beta with 5-carboxy-dC (5-caC) at the templating position

Classification:

gene regulation/dna

Authors:

Howard, M.J., Foley, K.G., Shock, D.D., Batra, V.K., Wilson, S.H.

Citation:

Molecular basis for the faithful replication of 5-methylcytosine and its oxidized forms by DNA Polymerase ß.
J. Biol. Chem. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.457Å R work:0.202R free:0.289

NDB ID:

6N2T

PDB ID:

6N2T 

Release:

2019-03-27

Title:

Ternary complex crystal structure of DNA polymerase Beta with 5-hydroxymethyl-dC (5-hmC) at the templating position

Classification:

gene regulation/dna

Authors:

Howard, M.J., Foley, K.G., Shock, D.D., Batra, V.K., Wilson, S.H.

Citation:

Molecular basis for the faithful replication of 5-methylcytosine and its oxidized forms by DNA Polymerase ß.
J. Biol. Chem. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.6Å R work:0.198R free:0.29

NDB ID:

5ZAD

PDB ID:

5ZAD 

Release:

2019-03-20

Title:

Human topoisomerase II beta in complex with DNA

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Sun, L.Y., Zhu, L.W., Tang, Y.J.

Citation:

Increasing the distance between two monomers of topoisomerase II beta under the action of antitumor agent 4 beta-sulfur-(benzimidazole) 4'-demethylepipodophyllotoxin.
Sci Rep 8 pp.14949 - 14949 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.54Å R work:0.18R free:0.227

NDB ID:

5ZX2

PDB ID:

5ZX2 

Release:

2019-03-20

Title:

Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ECF sigma factor sigma H and 7nt RNA

Classification:

TRANSCRIPTION/DNA/RNA

Authors:

Li, L., Fang, C., Zhuang, N., Wang, T., Zhang, Y.

Citation:

Structural basis for transcription initiation by bacterial ECF sigma factors.
Nat Commun 10 pp.1153 - 1153 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.8Å R work:0.219R free:0.254

NDB ID:

6CPQ

PDB ID:

6CPQ 

Release:

2019-03-20

Title:

Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable CTP

Classification:

Transferase/DNA

Authors:

Koag, M.-C., Lee, S.

Citation:

Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable CTP
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.93Å R work:0.19R free:0.238