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As of 25-May-2022 number of released structures: 12098
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Polymer Type: All + Protein Function: All + Structural Features: All + Experimental Method: All

Results: 8271  Download results as an excel file       Gallery view

NDB ID:

7MZ0

PDB ID:

7MZ0 

Release:

2022-05-25

Title:

Structure of human DNA polymerase beta complexed with dzA as the template base in a 1-nucleotide gapped DNA

Classification:

TRANSFERASE/DNA

Authors:

Koag, M.-C., Lee, S.

Citation:

Structure Of Human Dna Polymerase Beta Complexed With dzA As The Template Base In A 1-Nucleotide Gapped Dna
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.021Å R work:0.221R free:0.275

NDB ID:

7MZ1

PDB ID:

7MZ1 

Release:

2022-05-25

Title:

Structure of human DNA polymerase beta complexed with dzA in the template base paired with incoming non-hydrolyzable TTP

Classification:

TRANSFERASE/DNA

Authors:

Koag, M.-C., Lee, S.

Citation:

Structure of human DNA polymerase beta complexed with dzA in the template base paired with incoming non-hydrolyzable TTP
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.175Å R work:0.2R free:0.258

NDB ID:

7MZ2

PDB ID:

7MZ2 

Release:

2022-05-25

Title:

Structure of human DNA polymerase beta complexed with dzA at N-1 of the template base paired with incoming dTTP

Classification:

TRANSFERASE/DNA

Authors:

Koag, M.-C., Lee, S.

Citation:

Structure of human DNA polymerase beta complexed with dzA at N-1 of the template base paired with incoming dTTP
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.088Å R work:0.196R free:0.242

NDB ID:

7RH2

PDB ID:

7RH2 

Release:

2022-05-25

Title:

IRF4 Transcription factor mutant -K59R

Classification:

TRANSCRIPTION

Authors:

Sundararaj, S., Seneviratne, S., Williams, S.J., Enders, A., Casarotto, M.G.

Citation:

The molecular basis for the development of adult T-cell leukemia/lymphoma in patients with an IRF4 K59R mutation.
Protein Sci. 31 pp.787 - 796 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.47Å R work:0.203R free:0.24

NDB ID:

7T18

PDB ID:

7T18 

Release:

2022-05-25

Title:

Rev1 Ternary Complex with dTTP and Ca2+

Classification:

TRANSFERASE/DNA

Authors:

Freudenthal, B.D., Weaver, T.M.

Citation:

Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.7Å R work:0.182R free:0.225

NDB ID:

7T19

PDB ID:

7T19 

Release:

2022-05-25

Title:

Rev1 Ternary Complex with dGTP and Ca2+

Classification:

TRANSFERASE/DNA

Authors:

Freudenthal, B.D., Weaver, T.M.

Citation:

Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.01Å R work:0.181R free:0.242

NDB ID:

7T1A

PDB ID:

7T1A 

Release:

2022-05-25

Title:

Rev1 Ternary Complex with dATP and Ca2+

Classification:

TRANSFERASE/DNA

Authors:

Freudenthal, B.D., Weaver, T.M.

Citation:

Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.81Å R work:0.193R free:0.229

NDB ID:

7T1B

PDB ID:

7T1B 

Release:

2022-05-25

Title:

Rev1 Ternary Complex with rCTP and Ca2+

Classification:

TRANSFERASE/DNA

Authors:

Freudenthal, B.D., Weaver, T.M.

Citation:

Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.75Å R work:0.182R free:0.228

NDB ID:

7X1N

PDB ID:

7X1N 

Release:

2022-05-25

Title:

Crystal structure of MEF2D-MRE complex

Classification:

TRANSCRIPTION/DNA

Authors:

Zhang, M., Zhang, H., Li, Z., Bai, L., Wang, Q., Li, J., Jiang, M., Xue, Q., Cheng, N., Zhang, W., Mao, D., Chen, Z., Huang, J., Meng, G., Chen, Z., Chen, S.J.

Citation:

Functional, structural and molecular characterizations of leukemogenic driver MEF2D-HNRNPUL1 fusion.
Blood pp. - 2022

Experiment:

X-RAY DIFFRACTION Resolution:3.315Å R work:0.242R free:0.274

NDB ID:

7T8K

PDB ID:

7T8K 

Release:

2022-05-18

Title:

BrxR from Acinetobacter BREX type I phage restriction system bound to DNA

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Luyten, Y.A., Hausman, D.E., Young, J.C., Doyle, L.A., Higashi, K.M., Ubilla-Rodriguez, N.C., Lambert, A.R., Arroyo, C.S., Forsberg, K.J., Morgan, R.D., Stoddard, B.L., Kaiser, B.K.

Citation:

Identification and characterization of the WYL BrxR protein and its gene as separable regulatory elements of a BREX phage restriction system.
Nucleic Acids Res. pp. - 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.3Å R work:0.195R free:0.237

NDB ID:

7VE5

PDB ID:

7VE5 

Release:

2022-05-18

Title:

C-terminal domain of VraR

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Kumar, J.V., Tseng, T.S., Lou, Y.C., Wei, S.Y., Wu, T.H., Tang, H.C., Chiu, Y.C., Hsu, C.H., Chen, C.

Citation:

Structural insights into DNA binding domain of vancomycin-resistance-associated response regulator in complex with its promoter DNA from Staphylococcus aureus.
Protein Sci. 31 pp.e4286 - e4286 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.0Å R work:0.194R free:0.254

NDB ID:

7WGW

PDB ID:

7WGW 

Release:

2022-05-18

Title:

NMR Solution Structure of a cGMP Fill-in Vacancy G-quadruplex Formed in the Oxidized BLM Gene Promoter

Classification:

DNA

Authors:

Wang, K.B., Liu, Y., Li, Y., Dickerhoff, J., Li, J., Yang, M.H., Yang, D., Kong, L.Y.

Citation:

Oxidative Damage Induces a Vacancy G-Quadruplex That Binds Guanine Metabolites: Solution Structure of a cGMP Fill-in Vacancy G-Quadruplex in the Oxidized BLM Gene Promoter.
J.Am.Chem.Soc. 144 pp.6361 - 6372 2022

Experiment:

SOLUTION NMR

NDB ID:

7F9H

PDB ID:

7F9H 

Release:

2022-05-11

Title:

complex structure of EnrR-DNA

Classification:

DNA BINDING PROTEIN

Authors:

Ma, R., Liu, Y., Gan, J., Qiao, H., Ma, J., Zhang, Y., Bu, Y., Shao, S., Zhang, Y., Wang, Q.

Citation:

Xenogeneic nucleoid-associated EnrR thwarts H-NS silencing of bacterial virulence with unique DNA binding.
Nucleic Acids Res. 50 pp.3777 - 3798 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.78Å R work:0.2R free:0.222

NDB ID:

7KSS

PDB ID:

7KSS 

Release:

2022-05-11

Title:

DNA Polymerase Mu, dGTP:Ct Pre-Catalytic Ground State Ternary Complex, 10 mM Ca2+ (20min)

Classification:

REPLICATION

Authors:

Jamsen, J.A., Sassa, A., Shock, D.D., Beard, W.A., Wilson, S.H.

Citation:

Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide.
Nat Commun 12 pp.2059 - 2059 2021

Experiment:

X-RAY DIFFRACTION Resolution:1.503Å R work:0.159R free:0.176

NDB ID:

7KTB

PDB ID:

7KTB 

Release:

2022-05-11

Title:

DNA Polymerase Mu, 8-oxodGTP:Ct Reaction State Ternary Complex, 10 mM Mn2+ (40min)

Classification:

REPLICATION

Authors:

Jamsen, J.A., Sassa, A., Shock, D.D., Beard, W.A., Wilson, S.H.

Citation:

Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide.
Nat Commun 12 pp.2059 - 2059 2021

Experiment:

X-RAY DIFFRACTION Resolution:1.576Å R work:0.158R free:0.177

NDB ID:

7KTC

PDB ID:

7KTC 

Release:

2022-05-11

Title:

DNA Polymerase Mu, 8-oxodGTP:Ct Product State Ternary Complex, 10 mM Mn2+ (120min)

Classification:

REPLICATION

Authors:

Jamsen, J.A., Sassa, A., Shock, D.D., Beard, W.A., Wilson, S.H.

Citation:

Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide.
Nat Commun 12 pp.2059 - 2059 2021

Experiment:

X-RAY DIFFRACTION Resolution:1.653Å R work:0.155R free:0.176

NDB ID:

7KTD

PDB ID:

7KTD 

Release:

2022-05-11

Title:

DNA Polymerase Mu, 8-oxodGTP:Ct Product State Ternary Complex, 10 mM Mn2+ (960min)

Classification:

REPLICATION

Authors:

Jamsen, J.A., Sassa, A., Shock, D.D., Beard, W.A., Wilson, S.H.

Citation:

Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide.
Nat Commun 12 pp.2059 - 2059 2021

Experiment:

X-RAY DIFFRACTION Resolution:1.551Å R work:0.159R free:0.178

NDB ID:

7KTH

PDB ID:

7KTH 

Release:

2022-05-11

Title:

DNA Polymerase Mu, 8-oxodGTP:Ct Product State Ternary Complex, 10 mM Mg2+ (2160min)

Classification:

REPLICATION

Authors:

Jamsen, J.A., Sassa, A., Shock, D.D., Beard, W.A., Wilson, S.H.

Citation:

Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide.
Nat Commun 12 pp.2059 - 2059 2021

Experiment:

X-RAY DIFFRACTION Resolution:1.476Å R work:0.166R free:0.19

NDB ID:

7KTI

PDB ID:

7KTI 

Release:

2022-05-11

Title:

DNA Polymerase Mu, 8-oxodGTP:Ct Product State Ternary Complex, 20 uM Mn2+ (120min)

Classification:

REPLICATION

Authors:

Jamsen, J.A., Sassa, A., Shock, D.D., Beard, W.A., Wilson, S.H.

Citation:

Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide.
Nat Commun 12 pp.2059 - 2059 2021

Experiment:

X-RAY DIFFRACTION Resolution:1.57Å R work:0.161R free:0.179

NDB ID:

7KTJ

PDB ID:

7KTJ 

Release:

2022-05-11

Title:

DNA Polymerase Mu (K438D), 8-oxodGTP:Ct Pre-Catalytic Ground State Ternary Complex, 20 mM Ca2+ (120min)

Classification:

REPLICATION

Authors:

Jamsen, J.A., Sassa, A., Shock, D.D., Beard, W.A., Wilson, S.H.

Citation:

Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide.
Nat Commun 12 pp.2059 - 2059 2021

Experiment:

X-RAY DIFFRACTION Resolution:1.452Å R work:0.16R free:0.184

NDB ID:

7KTK

PDB ID:

7KTK 

Release:

2022-05-11

Title:

DNA Polymerase Mu (K438D), 8-oxodGTP:Ct Ground State Ternary Complex, 50 mM Mg2+ (90min)

Classification:

REPLICATION

Authors:

Jamsen, J.A., Sassa, A., Shock, D.D., Beard, W.A., Wilson, S.H.

Citation:

Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide.
Nat Commun 12 pp.2059 - 2059 2021

Experiment:

X-RAY DIFFRACTION Resolution:1.419Å R work:0.142R free:0.168

NDB ID:

7KTL

PDB ID:

7KTL 

Release:

2022-05-11

Title:

DNA Polymerase Mu (K438D), 8-oxodGTP:Ct Product State Ternary Complex, 50 mM Mn2+ (90min)

Classification:

REPLICATION

Authors:

Jamsen, J.A., Sassa, A., Shock, D.D., Beard, W.A., Wilson, S.H.

Citation:

Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide.
Nat Commun 12 pp.2059 - 2059 2021

Experiment:

X-RAY DIFFRACTION Resolution:1.421Å R work:0.158R free:0.173

NDB ID:

7KTM

PDB ID:

7KTM 

Release:

2022-05-11

Title:

DNA Polymerase Mu (K438D), 8-oxodGTP:Ct Reaction State Ternary Complex, 50 mM Mn2+ (30min)

Classification:

REPLICATION

Authors:

Jamsen, J.A., Sassa, A., Shock, D.D., Beard, W.A., Wilson, S.H.

Citation:

Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide.
Nat Commun 12 pp.2059 - 2059 2021

Experiment:

X-RAY DIFFRACTION Resolution:1.528Å R work:0.16R free:0.18

NDB ID:

7NQF

PDB ID:

7NQF 

Release:

2022-05-04

Title:

Prim-Pol Domain of CRISPR-associated Prim-Pol (CAPP) from Marinitoga sp. 1137 with dsDNA

Classification:

TRANSFERASE

Authors:

Li, A.W.H., Zabrady, K., Bainbridge, L.J., Zabrady, M., Naseem-Khan, S., Berger, M.B., Kolesar, P., Cisneros, G.A., Doherty, A.J.

Citation:

Molecular basis for the initiation of DNA primer synthesis.
Nature pp. - 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.02Å R work:0.212R free:0.259

NDB ID:

7P9J

PDB ID:

7P9J 

Release:

2022-05-04

Title:

Prim-Pol Domain of CRISPR-associated Prim-Pol (CAPP) from Marinitoga sp. 1137 - Primer Initiation Complex

Classification:

TRANSFERASE

Authors:

Li, A.W.H., Zabrady, K., Bainbridge, L.J., Zabrady, M., Naseem-Khan, S., Berger, M.B., Kolesar, P., Cisneros, G.A., Doherty, A.J.

Citation:

Molecular basis for the initiation of DNA primer synthesis.
Nature pp. - 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.9Å R work:0.227R free:0.259

NDB ID:

7QAZ

PDB ID:

7QAZ 

Release:

2022-05-04

Title:

Prim-Pol Domain of CRISPR-associated Prim-Pol (CAPP) from Marinitoga sp. 1137 - Primer Initiation Complex

Classification:

TRANSFERASE

Authors:

Li, A.W.H., Zabrady, K., Bainbridge, L.J., Zabrady, M., Naseem-Khan, S., Berger, M.B., Kolesar, P., Cisneros, G.A., Doherty, A.J.

Citation:

Molecular basis for the initiation of DNA primer synthesis.
Nature pp. - 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.11Å R work:0.209R free:0.26

NDB ID:

7U72

PDB ID:

7U72 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA ternary mismatch complex:ground state at pH7.0 (K+ MES) with 1 Ca2+ ion

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.53Å R work:0.187R free:0.219

NDB ID:

7U73

PDB ID:

7U73 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 0.5 mM Mn2+ for 1800s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.56Å R work:0.18R free:0.213

NDB ID:

7U74

PDB ID:

7U74 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 0.5 mM Mn2+ for 1800s then with 10 mM Mn2+ for 30s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.52Å R work:0.189R free:0.224

NDB ID:

7U75

PDB ID:

7U75 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 0.5 mM Mn2+ for 1800s then with 10 mM Mn2+ for 90s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.55Å R work:0.186R free:0.221

NDB ID:

7U76

PDB ID:

7U76 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 0.5 mM Mn2+ for 1800s then with 10 mM Mn2+ for 300s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.69Å R work:0.182R free:0.219

NDB ID:

7U77

PDB ID:

7U77 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 1.0 mM Mg2+ for 40s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.58Å R work:0.183R free:0.202

NDB ID:

7U78

PDB ID:

7U78 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 1.0 mM Mg2+ for 80s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.61Å R work:0.186R free:0.217

NDB ID:

7U79

PDB ID:

7U79 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 1.0 mM Mg2+ for 140s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.69Å R work:0.175R free:0.22

NDB ID:

7U7A

PDB ID:

7U7A 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 1.0 mM Mg2+ for 200s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.58Å R work:0.186R free:0.216

NDB ID:

7U7B

PDB ID:

7U7B 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 1.0 mM Mg2+ for 250s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.58Å R work:0.178R free:0.206

NDB ID:

7U7C

PDB ID:

7U7C 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 1.0 mM Mg2+ for 300s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.55Å R work:0.18R free:0.212

NDB ID:

7U7D

PDB ID:

7U7D 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 30s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.57Å R work:0.181R free:0.217

NDB ID:

7U7E

PDB ID:

7U7E 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 60s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.58Å R work:0.182R free:0.217

NDB ID:

7U7F

PDB ID:

7U7F 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 90s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.65Å R work:0.2R free:0.246

NDB ID:

7U7G

PDB ID:

7U7G 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 120s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.77Å R work:0.175R free:0.209

NDB ID:

7U7I

PDB ID:

7U7I 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 180s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.57Å R work:0.18R free:0.219

NDB ID:

7U7J

PDB ID:

7U7J 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 300s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.58Å R work:0.181R free:0.212

NDB ID:

7U7K

PDB ID:

7U7K 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 600s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.67Å R work:0.176R free:0.221

NDB ID:

7U7L

PDB ID:

7U7L 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 1.0 mM Mg2+ for 300s with flipped-out product

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.47Å R work:0.187R free:0.193

NDB ID:

7U7R

PDB ID:

7U7R 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex:no Me2+ soaking

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.64Å R work:0.192R free:0.218

NDB ID:

7U7S

PDB ID:

7U7S 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 0.025 mM Mg2+ for 600s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.6Å R work:0.187R free:0.207

NDB ID:

7U7T

PDB ID:

7U7T 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 0.05 mM Mg2+ for 600s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.55Å R work:0.188R free:0.202

NDB ID:

7U7U

PDB ID:

7U7U 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 0.1 mM Mg2+ for 600s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.54Å R work:0.193R free:0.221

NDB ID:

7U7V

PDB ID:

7U7V 

Release:

2022-05-04

Title:

Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 0.4 mM Mg2+ for 600s

Classification:

TRANSFERASE/DNA

Authors:

Chang, C., Lee Luo, C., Gao, Y.

Citation:

In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun 13 pp.2346 - 2346 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.65Å R work:0.185R free:0.217