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As of 19-Jul-2017 number of released structures: 9000
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Polymer Type: All + RNA Type: All + Protein Function: All + Experimental Method: All + RNA Sequence Type: All RNA Sequence

Results: 3327  Download results as an excel file       Gallery view

NDB ID:

 5MPG

PDB ID:

5MPG 

Release:

2017-07-05

Title:

Solution NMR structure of hnRNP A1 RRM1 in complex with 5'-UUAGGUC-3' RNA

Classification:

SPLICING

Authors:

Barraud, P., Allain, F.H.-T.

Citation:

Solution NMR structure of hnRNP A1 RRM1 in complex with 5'-UUAGGUC-3' RNA
Elife pp. - 2017

Experiment:

 SOLUTION NMR

NDB ID:

 5MPL

PDB ID:

5MPL 

Release:

2017-07-05

Title:

hnRNP A1 RRM2 in complex with 5'-UCAGUU-3' RNA

Classification:

SPLICING

Authors:

Beusch, I., Barraud, P., Moursy, A., Clery, A., Allain, F.H.

Citation:

Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7.
Elife 6 pp. - 2017

Experiment:

 SOLUTION NMR

NDB ID:

 5O3J

PDB ID:

5O3J 

Release:

2017-07-05

Title:

Crystal structure of TIA-1 RRM2 in complex with RNA

Classification:

RNA BINDING PROTEIN

Authors:

Sonntag, M., Jagtap, P., Simon, B., Appavou, M.S., Geerlof, A., Stehle, R., Gabel, F., Hennig, J., Sattler, M.

Citation:

Segmental, domain-selective perdeuteration and small angle neutron scattering for structural analysis of multi-domain proteins.
Angew. Chem. Int. Ed. Engl. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.97Å R work:0.25R free:0.311

NDB ID:

 5T3K

PDB ID:

5T3K 

Release:

2017-07-05

Title:

Fluorescence detection of RNA-ligand binding and crystal structure determination of ribosomal decoding site RNA using a heavy atom containing fluorescent ribonucleoside

Classification:

RNA

Authors:

Nuthanakanti, A., Boerneke, M.A., Hermann, T., Srivatsan, S.G.

Citation:

Structure of the Ribosomal RNA Decoding Site Containing a Selenium-Modified Responsive Fluorescent Ribonucleoside Probe.
Angew. Chem. Int. Ed. Engl. 56 pp.2640 - 2644 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.142Å R work:0.197R free:0.246

NDB ID:

 5TWS

PDB ID:

5TWS 

Release:

2017-07-05

Title:

Post-catalytic complex of human Polymerase Mu (H329A) with newly incorporated UTP

Classification:

TRANSFERASE/DNA

Authors:

Moon, A.F., Pryor, J.M., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme Polymerase Mu
Nucleic Acids Res. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.85Å R work:0.166R free:0.2

NDB ID:

 5UED

PDB ID:

5UED 

Release:

2017-07-05

Title:

RNA primer-template complex with guanosine dinucleotide ligand G(5')pp(5')G

Classification:

RNA

Authors:

Tam, C.P., Zhang, W., Walton, T., Fahrenbach, A., Birrane, G., Szostak, J.W.

Citation:

Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex
Proc.Natl.Acad.Sci.Usa pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.5Å R work:0.21R free:0.232

NDB ID:

 5UEE

PDB ID:

5UEE 

Release:

2017-07-05

Title:

RNA primer-template complex with guanosine dinucleotide ligand G(5')ppp(5')G

Classification:

RNA

Authors:

Tam, C.P., Zhang, W., Walton, T., Fahrenbach, A., Birrane, G., Szostak, J.W.

Citation:

Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex
Proc.Natl.Acad.Sci.Usa pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.9Å R work:0.231R free:0.274

NDB ID:

 5UEF

PDB ID:

5UEF 

Release:

2017-07-05

Title:

RNA primer-template complex with guanosine dinucleotide p(5')G(3')p(5')G ligand

Classification:

RNA

Authors:

Tam, C.P., Zhang, W., Walton, T., Fahrenbach, A., Birrane, G., Szostak, J.W.

Citation:

Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex
Proc.Natl.Acad.Sci.Usa pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.1Å R work:0.239R free:0.303

NDB ID:

 5UEG

PDB ID:

5UEG 

Release:

2017-07-05

Title:

RNA primer-template complex with guanosine dinucleotide G(5')pppp(5')G ligand

Classification:

RNA

Authors:

Tam, C.P., Zhang, W., Walton, T., Fahrenbach, A., Birrane, G., Szostak, J.W.

Citation:

Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex
Proc.Natl.Acad.Sci.Usa pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.6Å R work:0.207R free:0.301

NDB ID:

 5V3I

PDB ID:

5V3I 

Release:

2017-07-05

Title:

Crystal structure of the VS ribozyme - wild-type C634

Classification:

RNA

Authors:

DasGupta, S., Suslov, N.B., Piccirilli, J.A.

Citation:

Structural basis for substrate helix remodeling and cleavage loop activation in the Varkud satellite ribozyme.
J. Am. Chem. Soc. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:3.293Å R work:0.216R free:0.246

NDB ID:

 5VZ8

PDB ID:

5VZ8 

Release:

2017-07-05

Title:

Post-catalytic complex of human Polymerase Mu (G433A) mutant with incoming UTP

Classification:

TRANSFERASE/DNA

Authors:

Moon, A.F., Pryor, J.M., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme Polymerase Mu
Nucleic Acids Res. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.601Å R work:0.171R free:0.193

NDB ID:

 5VZB

PDB ID:

5VZB 

Release:

2017-07-05

Title:

Post-catalytic complex of human Polymerase Mu (G433S) mutant with incoming UTP

Classification:

TRANSFERASE/DNA

Authors:

Moon, A.F., Pryor, J.M., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme Polymerase Mu
Nucleic Acids Res. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.5Å R work:0.17R free:0.187

NDB ID:

 5VZE

PDB ID:

5VZE 

Release:

2017-07-05

Title:

Post-catalytic complex of human Polymerase Mu (W434A) mutant with incoming UTP

Classification:

TRANSFERASE/DNA

Authors:

Moon, A.F., Pryor, J.M., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme Polymerase Mu
Nucleic Acids Res. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.506Å R work:0.177R free:0.2

NDB ID:

 5VZH

PDB ID:

5VZH 

Release:

2017-07-05

Title:

Post-catalytic complex of human Polymerase Mu (W434H) mutant with incoming UTP

Classification:

TRANSFERASE/DNA

Authors:

Moon, A.F., Pryor, J.M., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme Polymerase Mu
Nucleic Acids Res. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.95Å R work:0.178R free:0.21

NDB ID:

 5WQ1

PDB ID:

5WQ1 

Release:

2017-07-05

Title:

Solution Structure of the first stem-loop of Escherichia coli DsrA RNA

Classification:

RNA

Authors:

Wu, P., Liu, X., Yang, L., Sun, Y., Gong, Q., Wu, J., Shi, Y.

Citation:

Conformational plasticity of DsrA sRNA for adaption multiple target regulation
NUCLEIC ACIDS RES. pp. - 2017

Experiment:

 SOLUTION NMR

NDB ID:

 5X21

PDB ID:

5X21 

Release:

2017-07-05

Title:

Crystal structure of Thermus thermophilus transcription initiation complex with GpA and pseudouridimycin (PUM)

Classification:

TRANSFERASE/DNA

Authors:

Maffioli, S.I., Zhang, Y., Degen, D., Carzaniga, T., Del Gatto, G., Serina, S., Monciardini, P., Mazzetti, C., Guglierame, P., Candiani, G., Chiriac, A.I., Facchetti, G., Kaltofen, P., Sahl, H.G., Deho, G., Donadio, S., Ebright, R.H.

Citation:

Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase.
Cell 169 pp.1240 - 1248.e23 2017

Experiment:

 X-RAY DIFFRACTION Resolution:3.323Å R work:0.231R free:0.28

NDB ID:

 5X22

PDB ID:

5X22 

Release:

2017-07-05

Title:

Crystal structure of Thermus thermophilus transcription initiation complex with GpA and CMPcPP

Classification:

TRANSFERASE/DNA

Authors:

Maffioli, S.I., Zhang, Y., Degen, D., Carzaniga, T., Del Gatto, G., Serina, S., Monciardini, P., Mazzetti, C., Guglierame, P., Candiani, G., Chiriac, A.I., Facchetti, G., Kaltofen, P., Sahl, H.G., Deho, G., Donadio, S., Ebright, R.H.

Citation:

Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase.
Cell 169 pp.1240 - 1248.e23 2017

Experiment:

 X-RAY DIFFRACTION Resolution:3.35Å R work:0.207R free:0.25

NDB ID:

 5MEI

PDB ID:

5MEI 

Release:

2017-06-28

Title:

Crystal structure of Agelastatin A bound to the 80S ribosome

Classification:

RIBOSOME

Authors:

McClary, B., Zinshteyn, B., Meyer, M., Jouanneau, M., Pellegrino, S., Yusupova, G., Schuller, A., Reyes, J.C.P., Lu, J., Guo, Z., Ayinde, S., Luo, C., Dang, Y., Romo, D., Yusupov, M., Green, R., Liu, J.O.

Citation:

Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A.
Cell Chem Biol 24 pp.605 - 613.e5 2017

Experiment:

 X-RAY DIFFRACTION Resolution:3.5Å R work:0.195R free:0.238

NDB ID:

 5VH7

PDB ID:

5VH7 

Release:

2017-06-28

Title:

Structure and dynamics of RNA repeat expansions that cause Huntington's Disease and myotonic dystrophy type 1

Classification:

RNA

Authors:

Chen, J.L., VanEtten, D.M., Fountain, M.A., Yildirim, I., Disney, M.D.

Citation:

Structure and dynamics of RNA repeat expansions that cause Huntington's Disease and myotonic dystrophy type 1.
Biochemistry pp. - 2017

Experiment:

 SOLUTION NMR

NDB ID:

 5VH8

PDB ID:

5VH8 

Release:

2017-06-28

Title:

Structure and dynamics of RNA repeat expansions that cause Huntington's Disease and myotonic dystrophy type 1

Classification:

RNA

Authors:

Chen, J.L., VanEtten, D.M., Fountain, M.A., Yildirim, I., Disney, M.D.

Citation:

Structure and dynamics of RNA repeat expansions that cause Huntington's Disease and myotonic dystrophy type 1.
Biochemistry pp. - 2017

Experiment:

 SOLUTION NMR

NDB ID:

 5VJ9

PDB ID:

5VJ9 

Release:

2017-06-28

Title:

Guanidine-II riboswitch P2 hairpin dimer from Pseudomonas aeruginosa

Classification:

RNA

Authors:

Reiss, C.W., Strobel, S.A.

Citation:

Structural basis for ligand binding to the guanidine-II riboswitch.
RNA pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.57Å R work:0.192R free:0.234

NDB ID:

 5VJB

PDB ID:

5VJB 

Release:

2017-06-28

Title:

Guanidine-II riboswitch P2 hairpin dimer with 5-bromoU substitution from Pseudomonas aeruginosa

Classification:

RNA

Authors:

Reiss, C.W., Strobel, S.A.

Citation:

Structural basis for ligand binding to the guanidine-II riboswitch.
RNA pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.1Å R work:0.215R free:0.238

NDB ID:

 5VP2

PDB ID:

5VP2 

Release:

2017-06-28

Title:

Crystal structure of the Thermus thermophilus 70S ribosome in complex with madumycin II and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution

Classification:

RIBOSOME

Authors:

Osterman, I.A., Khabibullina, N.F., Komarova, E.S., Kasatsky, P., Kartsev, V.G., Bogdanov, A.A., Dontsova, O.A., Konevega, A.L., Sergiev, P.V., Polikanov, Y.S.

Citation:

Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state.
Nucleic Acids Res. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.8Å R work:0.229R free:0.278

NDB ID:

 5VW1

PDB ID:

5VW1 

Release:

2017-06-28

Title:

Crystal structure of SpyCas9-sgRNA-AcrIIA4 ternary complex

Classification:

HYDROLASE

Authors:

Yang, H., Patel, D.J.

Citation:

Inhibition Mechanism of an Anti-CRISPR Suppressor AcrIIA4 Targeting SpyCas9.
Mol. Cell pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.598Å R work:0.178R free:0.226

NDB ID:

 5W0M

PDB ID:

5W0M 

Release:

2017-06-28

Title:

Structure of human TUT7 catalytic module (CM) in complex with U5 RNA

Classification:

TRANSFERASE/RNA

Authors:

Faehnle, C.R., Walleshauser, J., Joshua-Tor, L.

Citation:

Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis
Nat.Struct.Mol.Biol. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.298Å R work:0.188R free:0.228

NDB ID:

 5W0O

PDB ID:

5W0O 

Release:

2017-06-28

Title:

Structure of human TUT7 catalytic module (CM) in complex with dsRNA

Classification:

TRANSFERASE/RNA

Authors:

Faehnle, C.R., Walleshauser, J., Joshua-Tor, L.

Citation:

Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis
Nat.Struct.Mol.Biol. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.488Å R work:0.205R free:0.254

NDB ID:

 5W5I

PDB ID:

5W5I 

Release:

2017-06-28

Title:

Human IFIT1 dimer with PPP-AAAA

Classification:

RNA binding protein/RNA

Authors:

Abbas, Y.M., Martinez-Montero, S., Cencic, R., Pelletier, J., Damha, M.J., Pawelek, P.D., Nagar, B.

Citation:

Structural insights into IFIT1 dimerization and conformational changes associated with mRNA binding
To Be Published pp. - 0

Experiment:

 X-RAY DIFFRACTION Resolution:2.65Å R work:0.218R free:0.241

NDB ID:

 5W7N

PDB ID:

5W7N 

Release:

2017-06-28

Title:

2-Se-T2/4-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant

Classification:

HYDROLASE/DNA/RNA

Authors:

Fang, Z., Yang, F., Huang, Z.

Citation:

2-Se-T2/4-modified-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant
To Be Published pp. - 0

Experiment:

 X-RAY DIFFRACTION Resolution:1.8Å R work:0.192R free:0.232

NDB ID:

 5W7O

PDB ID:

5W7O 

Release:

2017-06-28

Title:

2-Se-T4-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant

Classification:

HYDROLASE/DNA/RNA

Authors:

Fang, Z., Yang, F., Huang, Z.

Citation:

2-Se-T-modified-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant
To Be Published pp. - 0

Experiment:

 X-RAY DIFFRACTION Resolution:1.75Å R work:0.182R free:0.228

NDB ID:

 5WWR

PDB ID:

5WWR 

Release:

2017-06-28

Title:

Crystal structure of human NSun6/tRNA/SFG

Classification:

TRANSFERASE/RNA

Authors:

Liu, R.J., Long, T., Li, J., Li, H., Wang, E.D.

Citation:

Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6
Nucleic Acids Res. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:3.096Å R work:0.195R free:0.235

NDB ID:

 5WWS

PDB ID:

5WWS 

Release:

2017-06-28

Title:

Crystal structure of human NSun6/tRNA/SAM

Classification:

TRANSFERASE/RNA

Authors:

Liu, R.J., Long, T., Li, J., Li, H., Wang, E.D.

Citation:

Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6
Nucleic Acids Res. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:3.247Å R work:0.193R free:0.222

NDB ID:

 5WWT

PDB ID:

5WWT 

Release:

2017-06-28

Title:

Crystal structure of human NSun6/tRNA

Classification:

TRANSFERASE/RNA

Authors:

Liu, R.J., Long, T., Li, J., Li, H., Wang, E.D.

Citation:

Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6
Nucleic Acids Res. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:3.197Å R work:0.19R free:0.223

NDB ID:

 5LQO

PDB ID:

5LQO 

Release:

2017-06-21

Title:

RNA duplex has central consecutive GA pairs flanked by G-C basepairs

Classification:

RNA

Authors:

Huang, L., Ashraf, S., Wang, J., Lilley, D.M.

Citation:

Control of box C/D snoRNP assembly by N(6)-methylation of adenine.
EMBO Rep. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.87Å R work:0.245R free:0.255

NDB ID:

 5LQT

PDB ID:

5LQT 

Release:

2017-06-21

Title:

RNA duplex has central consecutive GA pairs flanked by G-C basepairs

Classification:

RNA

Authors:

Huang, L., Ashraf, S., Wang, J., Lilley, D.M.

Citation:

Control of box C/D snoRNP assembly by N(6)-methylation of adenine.
EMBO Rep. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.5Å R work:0.219R free:0.227

NDB ID:

 5LR3

PDB ID:

5LR3 

Release:

2017-06-21

Title:

RNA duplex has central consecutive GA pairs flanked by G-U basepairs

Classification:

RNA

Authors:

Huang, L., Ashraf, S., Wang, J., Lilley, D.M.

Citation:

Control of box C/D snoRNP assembly by N(6)-methylation of adenine.
EMBO Rep. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.65Å R work:0.247R free:0.265

NDB ID:

 5LR4

PDB ID:

5LR4 

Release:

2017-06-21

Title:

RNA duplex has central consecutive GA pairs flanked by G-U basepairs with a methyl group on the adenine N6

Classification:

RNA

Authors:

Huang, L., Ashraf, S., Wang, J., Lilley, D.M.

Citation:

Control of box C/D snoRNP assembly by N(6)-methylation of adenine.
EMBO Rep. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.8Å R work:0.269R free:0.288

NDB ID:

 5LR5

PDB ID:

5LR5 

Release:

2017-06-21

Title:

N6-methyladenine is accommodated in a conventional A-U basepair

Classification:

RNA

Authors:

Huang, L., Ashraf, S., Wang, J., Lilley, D.M.

Citation:

Control of box C/D snoRNP assembly by N(6)-methylation of adenine.
EMBO Rep. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.4Å R work:0.247R free:0.287

NDB ID:

 5MGA

PDB ID:

5MGA 

Release:

2017-06-21

Title:

Structure of the Cpf1 endonuclease R-loop complex after DNA cleavage

Classification:

HYDROLASE

Authors:

Stella, S., Alcon, P., Montoya, G.

Citation:

Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage.
Nature 546 pp.559 - 563 2017

Experiment:

 X-RAY DIFFRACTION Resolution:3.0Å R work:0.241R free:0.265

NDB ID:

 5V1K

PDB ID:

5V1K 

Release:

2017-06-21

Title:

Structure of R-GNA dodecamer

Classification:

RNA

Authors:

Schlegel, M.K., Foster, D.J., Kel'in, A.V., Zlatev, I., Bisbe, A., Jayaraman, M., Lackey, J.G., Rajeev, K.G., Charisse, K., Harp, J., Pallan, P.S., Maier, M.A., Egli, M., Manoharan, M.

Citation:

Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA.
J. Am. Chem. Soc. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.18Å R work:0.167R free:0.224

NDB ID:

 5N9G

PDB ID:

5N9G 

Release:

2017-06-14

Title:

TFIIIB -TBP/Brf2/DNA and SANT domain of Bdp1-

Classification:

TRANSCRIPTION

Authors:

Gouge, J., Vannini, A., Guthertz, N.

Citation:

Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA Polymerase III transcription initiation
To Be Published pp. - 0

Experiment:

 X-RAY DIFFRACTION Resolution:2.7Å R work:0.194R free:0.233

NDB ID:

 5NFV

PDB ID:

5NFV 

Release:

2017-06-14

Title:

Crystal structure of catalytically inactive FnCas12 mutant bound to an R-loop structure containing a pre-crRNA mimic and full-length DNA target

Classification:

HYDROLASE

Authors:

Swarts, D.C., van der Oost, J., Jinek, M.

Citation:

Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.
Mol. Cell 66 pp.221 - 233.e4 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.501Å R work:0.205R free:0.237

NDB ID:

 5NG6

PDB ID:

5NG6 

Release:

2017-06-14

Title:

Crystal structure of FnCas12a bound to a crRNA

Classification:

HYDROLASE

Authors:

Swarts, D.C., van der Oost, J., Jinek, M.

Citation:

Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.
Mol. Cell 66 pp.221 - 233.e4 2017

Experiment:

 X-RAY DIFFRACTION Resolution:3.342Å R work:0.238R free:0.258

NDB ID:

 5UZZ

PDB ID:

5UZZ 

Release:

2017-06-14

Title:

Structure of wild type pre-miR21 apical loop

Classification:

TRANSPORT PROTEIN/RNA

Authors:

Shortridge, M.D., Walker, M.J., Pavelitz, T., Chen, Y., Yang, W., Varani, G.

Citation:

A Macrocyclic Peptide Ligand Binds the Oncogenic MicroRNA-21 Precursor and Suppresses Dicer Processing.
ACS Chem. Biol. 12 pp.1611 - 1620 2017

Experiment:

 SOLUTION NMR

NDB ID:

 5V1L

PDB ID:

5V1L 

Release:

2017-06-14

Title:

Structure of S-GNA dodecamer

Classification:

RNA

Authors:

Schlegel, M.K., Foster, D.J., Kel'in, A.V., Zlatev, I., Bisbe, A., Jayaraman, M., Lackey, J.G., Rajeev, K.G., Charisse, K., Harp, J., Pallan, P.S., Maier, M.A., Egli, M., Manoharan, M.

Citation:

Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA.
J. Am. Chem. Soc. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.2Å R work:0.133R free:0.152

NDB ID:

 5V2H

PDB ID:

5V2H 

Release:

2017-06-14

Title:

RNA octamer containing glycol nucleic acid, SgnT

Classification:

RNA

Authors:

Schlegel, M.K., Foster, D.J., Kel'in, A.V., Zlatev, I., Bisbe, A., Jayaraman, M., Lackey, J.G., Rajeev, K.G., Charisse, K., Harp, J., Pallan, P.S., Maier, M.A., Egli, M., Manoharan, M.

Citation:

Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA.
J. Am. Chem. Soc. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.08001Å R work:0.135R free:0.156

NDB ID:

 5XBL

PDB ID:

5XBL 

Release:

2017-06-14

Title:

Structure of nuclease in complex with associated protein

Classification:

HYDROLASE/RNA

Authors:

Guo, M., Wang, S., Zhu, Y., Wang, S., Xiong, Z., Yang, J., Xu, Z., Huang, Z.

Citation:

Structural basis of CRISPR-SpyCas9 inhibition by an anti-CRISPR protein
Nature 546 pp.436 - 439 2017

Experiment:

 X-RAY DIFFRACTION Resolution:3.052Å R work:0.237R free:0.277

NDB ID:

 5XH6

PDB ID:

5XH6 

Release:

2017-06-14

Title:

Crystal structure of the Acidaminococcus sp. BV3L6 Cpf1 RVR variant in complex with crRNA and target DNA (TATA PAM)

Classification:

HYDROLASE/RNA/DNA

Authors:

Nishimasu, H., Yamano, T., Gao, L., Zhang, F., Ishitani, R., Nureki, O.

Citation:

Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1
Mol.Cell 67 pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.0Å R work:0.174R free:0.209

NDB ID:

 5XH7

PDB ID:

5XH7 

Release:

2017-06-14

Title:

Crystal structure of the Acidaminococcus sp. BV3L6 Cpf1 RR variant in complex with crRNA and target DNA (TCCA PAM)

Classification:

HYDROLASE/RNA/DNA

Authors:

Nishimasu, H., Yamano, T., Gao, L., Zhang, F., Ishitani, R., Nureki, O.

Citation:

Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1
Mol.Cell 67 pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.0Å R work:0.182R free:0.214

NDB ID:

 5NEF

PDB ID:

5NEF 

Release:

2017-06-07

Title:

The structure of the G. violaceus guanidine II riboswitch P1 stem-loop with guanidine

Classification:

RNA

Authors:

Huang, L., Wang, J., Lilley, D.M.J.

Citation:

The Structure of the Guanidine-II Riboswitch.
Cell Chem Biol 24 pp.695 - 702.e2 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.91Å R work:0.202R free:0.257

NDB ID:

 5B63

PDB ID:

5B63 

Release:

2017-05-31

Title:

Crystal structures of E.coli arginyl-tRNA synthetase (ArgRS) in complex with substrate tRNA(Arg)

Classification:

LIGASE

Authors:

Zhou, M., Ye, S., Stephen, P., Zhang, R., Wang, E.D., Giege, R., Lin, S.X.

Citation:

Crystal structures of E.coli arginyl-tRNA synthetase (ArgRS) in complex with substrate tRNA(Arg)
To Be Published pp. - 0

Experiment:

 X-RAY DIFFRACTION Resolution:3.0Å R work:0.22R free:0.267

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