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As of 15-Nov-2017 number of released structures: 9208
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Polymer Type: All + RNA Type: All + Protein Function: All + Experimental Method: All + RNA Sequence Type: All RNA Sequence

Results: 3405  Download results as an excel file       Gallery view

NDB ID:

5OMW

PDB ID:

5OMW 

Release:

2017-11-15

Title:

Mutant T252A of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucyl-adenylate analogue in the aminoacylation conformation

Classification:

TRANSLATION

Authors:

Dulic, M., Cvetesic, N., Zivkovic, I., Palencia, A., Cusack, S., Bertosa, B., Gruic-Sovulj, I.

Citation:

Kinetic origin of substrate specificity in post-transfer editing by leucyl-tRNA synthetase.
J. Mol. Biol. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.6Å R work:0.218R free:0.264

NDB ID:

5ON2

PDB ID:

5ON2 

Release:

2017-11-15

Title:

Quaternary complex of mutant T252A of E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation

Classification:

TRANSLATION

Authors:

Dulic, M., Cvetesic, N., Zivkovic, I., Palencia, A., Cusack, S., Bertosa, B., Gruic-Sovulj, I.

Citation:

Kinetic origin of substrate specificity in post-transfer editing by leucyl-tRNA synthetase.
J. Mol. Biol. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.1Å R work:0.225R free:0.263

NDB ID:

5ON3

PDB ID:

5ON3 

Release:

2017-11-15

Title:

Quaternary complex of mutant T252A of E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of leucine in the aminoacylation conformation

Classification:

LIGASE

Authors:

Dulic, M., Cvetesic, N., Zivkovic, I., Palencia, A., Cusack, S., Bertosa, B., Gruic-Sovulj, I.

Citation:

Kinetic origin of substrate specificity in post-transfer editing by leucyl-tRNA synthetase.
J. Mol. Biol. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.1Å R work:0.241R free:0.277

NDB ID:

5ONH

PDB ID:

5ONH 

Release:

2017-11-15

Title:

Quaternary complex of wild type E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation

Classification:

LIGASE

Authors:

Dulic, M., Cvetesic, N., Zivkovic, I., Palencia, A., Cusack, S., Bertosa, B., Gruic-Sovulj, I.

Citation:

Kinetic origin of substrate specificity in post-transfer editing by leucyl-tRNA synthetase.
J. Mol. Biol. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.1Å R work:0.222R free:0.257

NDB ID:

5XC6

PDB ID:

5XC6 

Release:

2017-11-08

Title:

Dengue Virus 4 NS3 Helicase in complex with SSRNA SLA12

Classification:

HYDROLASE/RNA

Authors:

Swarbrick, C.M.D., Basavannacharya, C., Chan, K.W.K., Chan, S.A., Singh, D., Wei, N., Phoo, W.W., Luo, D., Lescar, J., Vasudevan, S.G.

Citation:

NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.9Å R work:0.201R free:0.256

NDB ID:

5OT2

PDB ID:

5OT2 

Release:

2017-11-01

Title:

RNA polymerase II elongation complex in the presence of 3d-Napht-A

Classification:

TRANSCRIPTION

Authors:

Malvezzi, S., Farnung, L., Aloisi, C.M.N., Angelov, T., Cramer, P., Sturla, S.J.

Citation:

Mechanism of RNA polymerase II stalling by DNA alkylation.
Proc. Natl. Acad. Sci. U.S.A. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.2Å R work:0.178R free:0.221

NDB ID:

5WTI

PDB ID:

5WTI 

Release:

2017-11-01

Title:

Crystal structure of the CRISPR-associated protein in complex with crRNA and DNA

Classification:

Hydrolase/DNA/RNA

Authors:

Wu, D., Guan, X., Zhu, Y., Ren, K., Huang, Z.

Citation:

Structural basis of stringent PAM recognition by CRISPR-C2c1 in complex with sgRNA
Cell Res. 27 pp.705 - 708 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.682Å R work:0.216R free:0.264

NDB ID:

5XJ2

PDB ID:

5XJ2 

Release:

2017-11-01

Title:

Structure of spRlmCD with U747 RNA

Classification:

TRANSFERASE/RNA

Authors:

Jiang, Y., Li, F., Wu, J., Shi, Y., Gong, Q.

Citation:

Structural insights into substrate selectivity of ribosomal RNA methyltransferase RlmCD
PLoS ONE 12 pp.e0185226 - e0185226 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.84Å R work:0.195R free:0.236

NDB ID:

5O58

PDB ID:

5O58 

Release:

2017-10-25

Title:

Structure of the inactive T.maritima PDE (TM1595) D80N D154N mutant with substrate 5'-pApG

Classification:

HYDROLASE

Authors:

Drexler, D.J., Muller, M., Rojas-Cordova, C.A., Bandera, A.M., Witte, G.

Citation:

Structural and Biophysical Analysis of the Soluble DHH/DHHA1-Type Phosphodiesterase TM1595 from Thermotoga maritima.
Structure pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:1.55Å R work:0.157R free:0.183

NDB ID:

5W3V

PDB ID:

5W3V 

Release:

2017-10-25

Title:

Crystal Structure of macaque APOBEC3H in complex with RNA

Classification:

ANTIVIRAL PROTEIN/RNA

Authors:

Bohn, J.A., Thummar, K., York, A., Raymond, A., Brown, W.C., Bieniasz, P.D., Hatziioannou, T., Smith, J.L.

Citation:

APOBEC3H structure reveals an unusual mechanism of interaction with duplex RNA.
Nat Commun 8 pp.1021 - 1021 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.243Å R work:0.181R free:0.221

NDB ID:

6B0B

PDB ID:

6B0B 

Release:

2017-10-25

Title:

Crystal structure of human APOBEC3H

Classification:

HYDROLASE/RNA

Authors:

Harris, R., Shaban, N.M., Shi, K., Lauer, K., Carpenter, M., Richards, C., Lopresti, M., Scalamango, D., Wang, J., Banerjee, S., Brown, W., Aihara, H., Harris, R.S.

Citation:

The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by a RNA-Mediated Dimerization Mechanism
Biorxiv pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.28006Å R work:0.352R free:0.362

NDB ID:

5NWQ

PDB ID:

5NWQ 

Release:

2017-10-18

Title:

The structure of the thermobifida fusca guanidine III riboswitch with guanidine.

Classification:

RNA

Authors:

Huang, L., Wang, J., Wilson, T.J., Lilley, D.M.J.

Citation:

Structure of the Guanidine III Riboswitch.
Cell Chem Biol pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:1.91Å R work:0.204R free:0.222

NDB ID:

5NY8

PDB ID:

5NY8 

Release:

2017-10-18

Title:

The structure of the thermobifida fusca guanidine III riboswitch with aminoguanidine

Classification:

RNA

Authors:

Huang, L., Wang, J., Wilson, T.J., Lilley, D.M.J.

Citation:

Structure of the Guanidine III Riboswitch.
Cell Chem Biol pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.04Å R work:0.188R free:0.225

NDB ID:

5NZ3

PDB ID:

5NZ3 

Release:

2017-10-18

Title:

The structure of the thermobifida fusca guanidine III riboswitch with methylguanidine

Classification:

RNA

Authors:

Huang, L., Wang, J., Wilson, T.J., Lilley, D.M.J.

Citation:

Structure of the Guanidine III Riboswitch.
Cell Chem Biol pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.059Å R work:0.218R free:0.273

NDB ID:

5NZ6

PDB ID:

5NZ6 

Release:

2017-10-18

Title:

The structure of the thermobifida fusca guanidine III riboswitch with guanidine in space group P3212.

Classification:

RNA

Authors:

Huang, L., Wang, J., Wilson, T.J., Lilley, D.M.J.

Citation:

Structure of the Guanidine III Riboswitch.
Cell Chem Biol pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.94Å R work:0.191R free:0.216

NDB ID:

5NZD

PDB ID:

5NZD 

Release:

2017-10-18

Title:

The structure of the thermobifida fusca guanidine III riboswitch in space group P212121.

Classification:

RNA

Authors:

Huang, L., Wang, J., Wilson, T.J., Lilley, D.M.J.

Citation:

Structure of the Guanidine III Riboswitch.
Cell Chem Biol pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.007Å R work:0.219R free:0.245

NDB ID:

5O62

PDB ID:

5O62 

Release:

2017-10-18

Title:

The structure of the thermobifida fusca guanidine III riboswitch with 1-Ethylguanidine.

Classification:

RNA

Authors:

Huang, L., Wang, J., Wilson, T.J., Lilley, D.M.J.

Citation:

Structure of the Guanidine III Riboswitch.
Cell Chem Biol pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.119Å R work:0.207R free:0.255

NDB ID:

5O69

PDB ID:

5O69 

Release:

2017-10-18

Title:

The structure of the thermobifida fusca guanidine III riboswitch with agmatine.

Classification:

RNA

Authors:

Huang, L., Wang, J., Wilson, T.J., Lilley, D.M.J.

Citation:

Structure of the Guanidine III Riboswitch.
Cell Chem Biol pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.319Å R work:0.242R free:0.27

NDB ID:

5OLA

PDB ID:

5OLA 

Release:

2017-10-18

Title:

Structure of mitochondrial transcription elongation complex in complex with elongation factor TEFM

Classification:

TRANSCRIPTION

Authors:

Hillen, H.S., Parshin, A.V., Agaronyan, K., Morozov, Y.I., Graber, J.J., Chernev, A., Schwinghammer, K., Urlaub, H., Anikin, M., Cramer, P., Temiakov, D.

Citation:

Mechanism of Transcription Anti-termination in Human Mitochondria.
Cell pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.904Å R work:0.242R free:0.275

NDB ID:

5TGP

PDB ID:

5TGP 

Release:

2017-10-18

Title:

DNA 8mer containing two 2SeT modifications

Classification:

DNA

Authors:

Zhang, W., Huang, Z.

Citation:

DNA 8mer containing two 2SeT modifications
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.6Å R work:0.188R free:0.208

NDB ID:

5VM9

PDB ID:

5VM9 

Release:

2017-10-18

Title:

Human Argonaute3 bound to guide RNA

Classification:

Hydrolase/RNA

Authors:

Park, M.S., Phan, H.D., Busch, F., Hinckley, S.H., Brackbill, J.A., Wysocki, V.H., Nakanishi, K.

Citation:

Human Argonaute3 has slicer activity.
Nucleic Acids Res. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.28Å R work:0.187R free:0.239

NDB ID:

5M8I

PDB ID:

5M8I 

Release:

2017-10-11

Title:

Solution structure of CUG-BP2 RRM3 in complex with 5'-UUUAA-3' RNA

Classification:

RNA BINDING PROTEIN

Authors:

Diarra Dit Konte, N., Krepl, M., Damberger, F.F., Ripin, N., Duss, O., Sponer, J., Allain, F.H.

Citation:

Aromatic side-chain conformational switch on the surface of the RNA Recognition Motif enables RNA discrimination.
Nat Commun 8 pp.654 - 654 2017

Experiment:

SOLUTION NMR

NDB ID:

5TKO

PDB ID:

5TKO 

Release:

2017-10-11

Title:

RNA heptamer duplex with one 2'-5'-linkage

Classification:

RNA

Authors:

Luo, Z., Sheng, J., Wang, R.

Citation:

RNA heptamer duplex with one 2'-5'-linkage
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.52Å R work:0.144R free:0.177

NDB ID:

5UD5

PDB ID:

5UD5 

Release:

2017-10-11

Title:

Crystal structure of the tRNA binding domain of Pyrrolysyl-tRNA synthetase bound to tRNA(Pyl)

Classification:

LIGASE/RNA

Authors:

Suzuki, T., Miller, C., Guo, L.T., Ho, J.M.L., Bryson, D.I., Wang, Y.S., Liu, D.R., Soll, D.

Citation:

Crystal structures reveal an elusive functional domain of pyrrolysyl-tRNA synthetase.
Nat. Chem. Biol. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.347Å R work:0.216R free:0.242

NDB ID:

5V6X

PDB ID:

5V6X 

Release:

2017-10-11

Title:

Crystal structure of the tRNA binding domain of Pyrrolysyl-tRNA synthetase mutant (32A NTD) bound to tRNA(Pyl)

Classification:

LIGASE/RNA

Authors:

Suzuki, T., Miller, C., Guo, L.T., Ho, J.M.L., Bryson, D.I., Wang, Y.S., Liu, D.R., Soll, D.

Citation:

Crystal structures reveal an elusive functional domain of pyrrolysyl-tRNA synthetase.
Nat. Chem. Biol. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.76Å R work:0.206R free:0.248

NDB ID:

5XWG

PDB ID:

5XWG 

Release:

2017-10-11

Title:

Crystal structure of a novel RNA motif that allows for precise positioning of a metal ion

Classification:

RNA

Authors:

Kanazawa, H., Kondo, J.

Citation:

Crystal structure of a novel RNA motif that allows for precise positioning of a single metal ion.
J. Inorg. Biochem. 176 pp.140 - 143 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.002Å R work:0.216R free:0.225

NDB ID:

5NEW

PDB ID:

5NEW 

Release:

2017-10-04

Title:

RNA-RNA base stacking in the crystal structure of an Hfq6:RNA dimer

Classification:

RNA

Authors:

Schulz, E.C., Seiler, M., Zuliani, C., Voigt, F., Rybin, V., Pogenberg, V., Mucke, N., Wilmanns, M., Gibson, T.J., Barabas, O.

Citation:

Intermolecular base stacking mediates RNA-RNA interaction in a crystal structure of the RNA chaperone Hfq.
Sci Rep 7 pp.9903 - 9903 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.511Å R work:0.196R free:0.252

NDB ID:

5OB3

PDB ID:

5OB3 

Release:

2017-10-04

Title:

iSpinach aptamer

Classification:

RNA

Authors:

Fernandez-Millan, P., Autour, A., Ennifar, E., Westhof, E., Ryckelynck, M.

Citation:

Crystal structure and fluorescence properties of the iSpinach aptamer in complex with DFHBI.
RNA pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.004Å R work:0.198R free:0.222

NDB ID:

5VR4

PDB ID:

5VR4 

Release:

2017-10-04

Title:

RNA octamer containing 2'-F-4'-OMe U.

Classification:

RNA

Authors:

Malek-Adamian, E., Guenther, D.C., Matsuda, S., Martinez-Montero, S., Zlatev, I., Harp, J., Burai Patrascu, M., Foster, D.J., Fakhoury, J., Perkins, L., Moitessier, N., Manoharan, R.M., Taneja, N., Bisbe, A., Charisse, K., Maier, M., Rajeev, K.G., Egli, M., Manoharan, M., Damha, M.J.

Citation:

4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing.
J. Am. Chem. Soc. 139 pp.14542 - 14555 2017

Experiment:

X-RAY DIFFRACTION Resolution:1.5Å R work:0.186R free:0.242

NDB ID:

5XOW

PDB ID:

5XOW 

Release:

2017-10-04

Title:

Crystal structure of T. thermophilus Argonaute protein complexed with a bulge 6'A7' on the target strand

Classification:

DNA BINDING PROTEIN

Authors:

Sheng, G., Gogakos, T., Wang, J., Zhao, H., Serganov, A., Juranek, S., Tuschl, T., Patel, D.J., Wang, Y.

Citation:

Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes
Nucleic Acids Res. 45 pp.9149 - 9163 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.902Å R work:0.214R free:0.256

NDB ID:

5BJO

PDB ID:

5BJO 

Release:

2017-09-27

Title:

Crystal structure of the Corn RNA aptamer in complex with DFHO, site-specific 5-iodo-U

Classification:

RNA

Authors:

Warner, K.D., Sjekloca, L., Song, W., Filonov, G.S., Jaffrey, S.R., Ferre-D'Amare, A.R.

Citation:

A homodimer interface without base pairs in an RNA mimic of red fluorescent protein.
Nat. Chem. Biol. 13 pp.1195 - 1201 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.35Å R work:0.179R free:0.228

NDB ID:

5BJP

PDB ID:

5BJP 

Release:

2017-09-27

Title:

Crystal structure of the Corn RNA aptamer in complex with DFHO, iridium hexammine soak

Classification:

RNA

Authors:

Warner, K.D., Sjekloca, L., Song, W., Filonov, G.S., Jaffrey, S.R., Ferre-D'Amare, A.R.

Citation:

A homodimer interface without base pairs in an RNA mimic of red fluorescent protein.
Nat. Chem. Biol. 13 pp.1195 - 1201 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.51Å R work:0.19R free:0.239

NDB ID:

5WZG

PDB ID:

5WZG 

Release:

2017-09-27

Title:

Structure of APUM23-GAAUUGACGG

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Bao, H., Wang, N., Wang, C., Jiang, Y., Wu, J., Shi, Y.

Citation:

Structural basis for the specific recognition of 18S rRNA by APUM23.
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.55Å R work:0.181R free:0.216

NDB ID:

5WZH

PDB ID:

5WZH 

Release:

2017-09-27

Title:

Structure of APUM23-GGAAUUGACGG

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Bao, H., Wang, N., Wang, C., Jiang, Y., Wu, J., Shi, Y.

Citation:

Structural basis for the specific recognition of 18S rRNA by APUM23.
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.509Å R work:0.187R free:0.229

NDB ID:

5WZI

PDB ID:

5WZI 

Release:

2017-09-27

Title:

Structure of APUM23-GGAGUUGACGG

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Bao, H., Wang, N., Wang, C., Jiang, Y., Wu, J., Shi, Y.

Citation:

Structural basis for the specific recognition of 18S rRNA by APUM23.
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.75Å R work:0.188R free:0.241

NDB ID:

5WZJ

PDB ID:

5WZJ 

Release:

2017-09-27

Title:

Structure of APUM23-GGAUUUGACGG

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Bao, H., Wang, N., Wang, C., Jiang, Y., Wu, J., Shi, Y.

Citation:

Structural basis for the specific recognition of 18S rRNA by APUM23.
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.101Å R work:0.176R free:0.196

NDB ID:

5WZK

PDB ID:

5WZK 

Release:

2017-09-27

Title:

Structure of APUM23-deletion-of-insert-region-GGAAUUGACGG

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Bao, H., Wang, N., Wang, C., Jiang, Y., Wu, J., Shi, Y.

Citation:

Structural basis for the specific recognition of 18S rRNA by APUM23.
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.8Å R work:0.18R free:0.224

NDB ID:

5LSN

PDB ID:

5LSN 

Release:

2017-09-20

Title:

SINEB2 element of the long non-coding RNA activator of translation AS Uchl1

Classification:

RNA

Authors:

Podbevsek, P., Fasolo, F., Bon, C., Cimatti, L., Reisser, S., Carninci, P., Bussi, G., Zucchelli, S., Plavec, J., Gustincich, S.

Citation:

Structural determinants of the SINEB2 element embedded in the long non-coding RNA activator of translation AS Uchl1
To Be Published pp. - 0

Experiment:

SOLUTION NMR

NDB ID:

5VAJ

PDB ID:

5VAJ 

Release:

2017-09-13

Title:

BhRNase H - amide-RNA/DNA complex

Classification:

hydrolase/rna/dna

Authors:

Mutisya, D., Hardcastle, T., Cheruiyot, S.K., Pallan, P.S., Kennedy, S.D., Egli, M., Kelley, M.L., Smith, A.V.B., Rozners, E.

Citation:

Amide linkages mimic phosphates in RNA interactions with proteins and are well tolerated in the guide strand of short interfering RNAs.
Nucleic Acids Res. 45 pp.8142 - 8155 2017

Experiment:

X-RAY DIFFRACTION Resolution:1.95Å R work:0.165R free:0.216

NDB ID:

5W1H

PDB ID:

5W1H 

Release:

2017-09-13

Title:

Crystal structure of LbaCas13a (C2c2) bound to mature crRNA (24-nt spacer)

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Knott, G.J., East-Seletsky, A., Cofsky, J.C., Holton, J.M., Charles, E., O'Connell, M.R., Doudna, J.A.

Citation:

Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme.
Nat. Struct. Mol. Biol. 24 pp.825 - 833 2017

Experiment:

X-RAY DIFFRACTION Resolution:1.99Å R work:0.185R free:0.216

NDB ID:

5W1I

PDB ID:

5W1I 

Release:

2017-09-13

Title:

Crystal structure of LbaCas13a (C2c2) bound to mature crRNA (20-nt spacer)

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Knott, G.J., East-Seletsky, A., Cofsky, J.C., Holton, J.M., Charles, E., O'Connell, M.R., Doudna, J.A.

Citation:

Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme.
Nat. Struct. Mol. Biol. 24 pp.825 - 833 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.2Å R work:0.196R free:0.232

NDB ID:

5WLH

PDB ID:

5WLH 

Release:

2017-09-13

Title:

Crystal structure of LbaCas13a H328A (C2c2) bound to pre-crRNA (24-nt spacer)

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Knott, G.J., East-Seletsky, A., Cofsky, J.C., Holton, J.M., Charles, E., O'Connell, M.R., Doudna, J.A.

Citation:

Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme.
Nat. Struct. Mol. Biol. 24 pp.825 - 833 2017

Experiment:

X-RAY DIFFRACTION Resolution:1.80001Å R work:0.184R free:0.217

NDB ID:

5XWP

PDB ID:

5XWP 

Release:

2017-09-13

Title:

Crystal structure of LbuCas13a-crRNA-target RNA ternary complex

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Liu, L., Li, X., Ma, J., Li, Z., You, L., Wang, J., Wang, M., Zhang, X., Wang, Y.

Citation:

The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a.
Cell 170 pp.714 - 726.e10 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.086Å R work:0.218R free:0.243

NDB ID:

5OR0

PDB ID:

5OR0 

Release:

2017-08-30

Title:

NMR derived model of the 5'-splice site of SMN2 in complex with the 5'-end of U1 snRNA

Classification:

RNA

Authors:

Sivaramakrishnan, M., McCarthy, K.D., Campagne, S., Huber, S., Meier, S., Augustin, A., Heckel, T., Meistermann, H., Hug, M.N., Birrer, P., Moursy, A., Khawaja, S., Schmucki, R., Berntenis, N., Giroud, N., Golling, S., Tzouros, N., Banfai, B., Duran-Pacheco, G., Lamerz, J., Hsiu Liu, Y., Luebbers, T., Ratni, A., Ebeling, M., Clery, A., Paushkin, S., Krainer, A.R., Allain, F.H., Metzger, F.

Citation:

Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers
Nat Commun pp. - 2017

Experiment:

SOLUTION NMR

NDB ID:

5W4K

PDB ID:

5W4K 

Release:

2017-08-30

Title:

Crystal structure of the Thermus thermophilus 70S ribosome in complex with Klebsazolicin and bound to mRNA and A-, P- and E-site tRNAs at 2.7A resolution

Classification:

ribosome/antibiotic

Authors:

Metelev, M., Osterman, I.A., Ghilarov, D., Khabibullina, N.F., Yakimov, A., Shabalin, K., Utkina, I., Travin, D.Y., Komarova, E.S., Serebryakova, M., Artamonova, T., Khodorkovskii, M., Konevega, A.L., Sergiev, P.V., Severinov, K., Polikanov, Y.S.

Citation:

Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel.
Nat. Chem. Biol. 13 pp.1129 - 1136 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.7Å R work:0.206R free:0.252

NDB ID:

5KW1

PDB ID:

5KW1 

Release:

2017-08-23

Title:

Crystal Structure of the Two Tandem RRM Domains of PUF60 Bound to a Modified AdML Pre-mRNA 3' Splice Site Analogue

Classification:

splicing/dna

Authors:

Hsiao, H.-H., Crichlow, G.V., Albright, R.A., Murphy, J.W., Folta-Stogniew, E.J., Lolis, E.J., Braddock, D.T.

Citation:

Recognition of the 3' AdML intron by the alternative splicing factor PUF60
To be published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.1Å R work:0.219R free:0.237

NDB ID:

5WWW

PDB ID:

5WWW 

Release:

2017-08-23

Title:

Crystal structure of the KH1 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C complex with RNA

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Yang, L., Wang, C., Li, F., Zhang, J., Nayab, A., Wu, J., Shi, Y., Gong, Q.

Citation:

The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem. 292 pp.16221 - 16234 2017

Experiment:

X-RAY DIFFRACTION Resolution:1.798Å R work:0.172R free:0.209

NDB ID:

5WWX

PDB ID:

5WWX 

Release:

2017-08-23

Title:

Crystal structure of the KH2 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C complex with RNA

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Yang, L., Wang, C., Li, F., Zhang, J., Nayab, A., Wu, J., Shi, Y., Gong, Q.

Citation:

The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem. 292 pp.16221 - 16234 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.0Å R work:0.17R free:0.217

NDB ID:

5O6U

PDB ID:

5O6U 

Release:

2017-08-16

Title:

Structure of the Cascade-I-Fv R-loop complex from Shewanella putrefaciens

Classification:

ANTIVIRAL PROTEIN

Authors:

Pausch, P., Muller-Esparza, H., Gleditzsch, D., Altegoer, F., Randau, L., Bange, G.

Citation:

Structural Variation of Type I-F CRISPR RNA Guided DNA Surveillance.
Mol. Cell 67 pp.622 - 632.e4 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.25Å R work:0.252R free:0.285

NDB ID:

5O7H

PDB ID:

5O7H 

Release:

2017-08-16

Title:

Structure of the Cascade-I-Fv complex from Shewanella putrefaciens

Classification:

ANTIVIRAL PROTEIN

Authors:

Pausch, P., Muller-Esparza, H., Gleditzsch, D., Altegoer, F., Randau, L., Bange, G.

Citation:

Structural Variation of Type I-F CRISPR RNA Guided DNA Surveillance.
Mol. Cell 67 pp.622 - 632.e4 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.0Å R work:0.221R free:0.267