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As of 22-Apr-2015 number of released structures: 7484
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Polymer Type: All + RNA Type: All + Protein Function: All + Experimental Method: All + RNA Sequence Type: All RNA Sequence

Results: 2730  Download results as an excel file       Gallery view

NDB ID:

4YCO

PDB ID:

4YCO 

Release:

2015-04-22

Title:

E. coli dihydrouridine synthase C (DusC) in complex with tRNAPhe

Classification:

OXIDOREDUCTASE

Authors:

Byrne, R.T., Jenkins, H.T., Peters, D.T., Whelan, F., Stowell, J., Aziz, N., Kasatsky, P., Rodnina, M.V., Koonin, E.V., Konevega, A.L., Antson, A.A.

Citation:

Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases
Proc.Natl.Acad.Sci.USA pp. - 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.1Å R work:0.192R free:0.223

NDB ID:

4YCP

PDB ID:

4YCP 

Release:

2015-04-22

Title:

E. coli dihydrouridine synthase C (DusC) in complex with tRNATrp

Classification:

Oxidoreductase/RNA

Authors:

Byrne, R.T., Jenkins, H.T., Peters, D.T., Whelan, F., Stowell, J., Aziz, N., Kasatsky, P., Rodnina, M.V., Koonin, E.V., Konevega, A.L., Antson, A.A.

Citation:

Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases
Proc.Natl.Acad.Sci.USA pp. - 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.55Å R work:0.208R free:0.234

NDB ID:

4YLN

PDB ID:

4YLN 

Release:

2015-04-22

Title:

E. coli Transcription Initiation Complex - 17-bp spacer and 4-nt RNA

Classification:

TRANSCRIPTION/DNA/RNA

Authors:

Zuo, Y., Steitz, T.A.

Citation:

Crystal Structures of E. coli Transcription Initiation Complexes with a Complete Bubble
Mol.Cell pp. - 2015

Experiment:

X-RAY DIFFRACTION Resolution:5.5Å R work:0.244R free:0.328

NDB ID:

4YLO

PDB ID:

4YLO 

Release:

2015-04-22

Title:

E. coli Transcription Initiation Complex - 16-bp spacer and 4-nt RNA

Classification:

TRANSCRIPTION/DNA/RNA

Authors:

Zuo, Y., Steitz, T.A.

Citation:

Crystal Structures of E. coli Transcription Initiation Complexes with a Complete Bubble
Mol.Cell pp. - 2015

Experiment:

X-RAY DIFFRACTION Resolution:6.0Å R work:0.226R free:0.314

NDB ID:

4YLP

PDB ID:

4YLP 

Release:

2015-04-22

Title:

E. coli Transcription Initiation Complex - 16-bp spacer and 5-nt RNA

Classification:

TRANSCRIPTION/DNA/RNA

Authors:

Zuo, Y., Steitz, T.A.

Citation:

Crystal Structures of E. coli Transcription Initiation Complexes with a Complete Bubble
Mol.Cell pp. - 2015

Experiment:

X-RAY DIFFRACTION Resolution:5.5Å R work:0.23R free:0.313

NDB ID:

4YN6

PDB ID:

4YN6 

Release:

2015-04-22

Title:

Structural Insight reveals dynamics in repeating r(CAG) transcript found in Huntington's disease (HD) and Spinocerebellar ataxias (SCAs)

Classification:

RNA

Authors:

Kumar, A.

Citation:

Structural Insight reveals dynamics in repeating r(CAG) transcript found in Huntington's disease (HD) and Spinocerebellar ataxias (SCAs)
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.301Å R work:0.216R free:0.26

NDB ID:

2MN0

PDB ID:

2MN0 

Release:

2015-04-15

Title:

D loop of tRNA(Met)

Classification:

RNA

Authors:

Dyubankova, N., Sochacka, E., Kraszewska, K., Nawrot, B., Herdewijn, P., Lescrinier, E.

Citation:

Contribution of dihydrouridine in folding of the D-arm in tRNA.
Org.Biomol.Chem. pp. - 2015

Experiment:

SOLUTION NMR

NDB ID:

4WC2

PDB ID:

4WC2 

Release:

2015-04-15

Title:

Crystal structure of tRNA nucleotidyltransferase complexed with a primer tRNA and an incoming ATP analog

Classification:

TRANSFERASE/RNA

Authors:

Yamashita, S., Martinez, A., Tomita, K.

Citation:

Measurement of acceptor-TPsiC helix length of tRNA for terminal A76-addition by A-adding enzyme
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.8Å R work:0.215R free:0.267

NDB ID:

4WC3

PDB ID:

4WC3 

Release:

2015-04-15

Title:

Structure of tRNA-processing enzyme complex 1

Classification:

TRANSFERASE/RNA

Authors:

Yamashita, S., Martinez, A., Tomita, K.

Citation:

Measurement of acceptor-TPsiC helix length of tRNA for terminal A76-addition by A-adding enzyme
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:3.1Å R work:0.24R free:0.288

NDB ID:

4WC4

PDB ID:

4WC4 

Release:

2015-04-15

Title:

tRNA-processing enzyme complex 2

Classification:

TRANSFERASE/RNA

Authors:

Yamashita, S., Martinez, A., Tomita, K.

Citation:

Measurement of acceptor-TPsiC helix length of tRNA for terminal A76-addition by A-adding enzyme
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:3.501Å R work:0.276R free:0.301

NDB ID:

4WC5

PDB ID:

4WC5 

Release:

2015-04-15

Title:

Structure of tRNA-processing enzyme complex 3

Classification:

TRANSFERASE/RNA

Authors:

Yamashita, S., Martinez, A., Tomita, K.

Citation:

Measurement of acceptor-TPsiC helix length of tRNA for terminal A76-addition by A-adding enzyme
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:3.41Å R work:0.266R free:0.308

NDB ID:

4WC6

PDB ID:

4WC6 

Release:

2015-04-15

Title:

Structure of tRNA-processing enzyme complex 4

Classification:

TRANSFERASE/RNA

Authors:

Yamashita, S., Martinez, A., Tomita, K.

Citation:

Measurement of acceptor-TPsiC helix length of tRNA for terminal A76-addition by A-adding enzyme
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:3.41Å R work:0.266R free:0.327

NDB ID:

4WC7

PDB ID:

4WC7 

Release:

2015-04-15

Title:

Structure of tRNA-processing enzyme complex 5

Classification:

TRANSFERASE/RNA

Authors:

Yamashita, S., Martinez, A., Tomita, K.

Citation:

Measurement of acceptor-TPsiC helix length of tRNA for terminal A76-addition by A-adding enzyme
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:3.102Å R work:0.277R free:0.321

NDB ID:

4X0A

PDB ID:

4X0A 

Release:

2015-04-15

Title:

Structure of tRNA-processing enzyme complex 6

Classification:

TRANSFERASE/RNA

Authors:

Yamashita, S., Martinez, A., Tomita, K.

Citation:

Measurement of acceptor-TPsiC helix length of tRNA for terminal A76-addition by A-adding enzyme
To be published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:3.505Å R work:0.258R free:0.312

NDB ID:

4X0B

PDB ID:

4X0B 

Release:

2015-04-15

Title:

Structure of tRNA-processing enzyme complex 7

Classification:

TRANSFERASE/RNA

Authors:

Yamashita, S., Martinez, A., Tomita, K.

Citation:

Measurement of acceptor-TPsiC helix length of tRNA for terminal A76-addition by A-adding enzyme
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:3.2Å R work:0.267R free:0.303

NDB ID:

4YAZ

PDB ID:

4YAZ 

Release:

2015-04-15

Title:

3',3'-cGAMP riboswitch bound with 3',3'-cGAMP

Classification:

RNA

Authors:

Ren, A., Wang, X.C., Kellenberger, C.A., Rajashankar, K.R., Jones, R.A., Hammond, M.C., Patel, D.J.

Citation:

Structural Basis for Molecular Discrimination by a 3',3'-cGAMP Sensing Riboswitch.
Cell Rep 11 pp.1 - 12 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.0Å R work:0.212R free:0.249

NDB ID:

4YB0

PDB ID:

4YB0 

Release:

2015-04-15

Title:

3',3'-cGAMP riboswitch bound with c-di-GMP

Classification:

RNA

Authors:

Ren, A., Wang, X.C., Kellenberger, C.A., Rajashankar, K.R., Jones, R.A., Hammond, M.C., Patel, D.J.

Citation:

Structural Basis for Molecular Discrimination by a 3',3'-cGAMP Sensing Riboswitch.
Cell Rep 11 pp.1 - 12 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.121Å R work:0.228R free:0.261

NDB ID:

4YB1

PDB ID:

4YB1 

Release:

2015-04-15

Title:

20A Mutant c-di-GMP Vc2 Riboswitch bound with 3',3'-cGAMP

Classification:

RNA/RNA BINDING PROTEIN

Authors:

Ren, A., Wang, X.C., Kellenberger, C.A., Rajashankar, K.R., Jones, R.A., Hammond, M.C., Patel, D.J.

Citation:

Structural Basis for Molecular Discrimination by a 3',3'-cGAMP Sensing Riboswitch.
Cell Rep 11 pp.1 - 12 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.081Å R work:0.218R free:0.298

NDB ID:

2MZ1

PDB ID:

2MZ1 

Release:

2015-04-08

Title:

Solution structure of hnRNP C RRM in complex with 5'-UUUUC-3' RNA

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Cienikova, Z., Damberger, F.F., Hall, J., Allain, F.H., Maris, C.

Citation:

Structural and mechanistic insights into poly(uridine) tract recognition by the hnRNP C RNA recognition motif.
J.Am.Chem.Soc. 136 pp.14536 - 14544 2014

Experiment:

SOLUTION NMR

NDB ID:

4Y1I

PDB ID:

4Y1I 

Release:

2015-04-08

Title:

Lactococcus lactis yybP-ykoY Mn riboswitch bound to Mn2+

Classification:

RNA

Authors:

Price, I.R., Gaballa, A., Ding, F., Helmann, J.D., Ke, A.

Citation:

Mn(2+)-Sensing Mechanisms of yybP-ykoY Orphan Riboswitches.
Mol.Cell 57 pp.1110 - 1123 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.85Å R work:0.192R free:0.223

NDB ID:

4Y1J

PDB ID:

4Y1J 

Release:

2015-04-08

Title:

Lactococcus lactis yybP-ykoY Mn riboswitch A41U binding site mutant in presence of Mn2+

Classification:

RNA

Authors:

Price, I.R., Gaballa, A., Ding, F., Helmann, J.D., Ke, A.

Citation:

Mn(2+)-Sensing Mechanisms of yybP-ykoY Orphan Riboswitches.
Mol.Cell 57 pp.1110 - 1123 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.24Å R work:0.199R free:0.241

NDB ID:

4Y1M

PDB ID:

4Y1M 

Release:

2015-04-08

Title:

An Escherichia coli yybP-ykoY Mn riboswitch in the Mn2+-free state

Classification:

RNA

Authors:

Price, I.R., Gaballa, A., Ding, F., Helmann, J.D., Ke, A.

Citation:

Mn(2+)-Sensing Mechanisms of yybP-ykoY Orphan Riboswitches.
Mol.Cell 57 pp.1110 - 1123 2015

Experiment:

X-RAY DIFFRACTION Resolution:3.0Å R work:0.216R free:0.252

NDB ID:

4YHH

PDB ID:

4YHH 

Release:

2015-04-08

Title:

Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with tigecycline

Classification:

RIBOSOME

Authors:

Schedlbauer, A., Kaminishi, T., Ochoa-Lizarralde, B., Dhimole, N., Zhou, S., Lopez-Alonso, J.P., Connell, S.R., Fucini, P.

Citation:

Structural characterization of an alternative mode of tigecycline binding to the bacterial ribosome.
Antimicrob.Agents Chemother. 59 pp.2849 - 2854 2015

Experiment:

X-RAY DIFFRACTION Resolution:3.417Å R work:0.228R free:0.287

NDB ID:

NA3311

PDB ID:

4RUM 

Release:

2015-04-08

Title:

Crystal structure of the NiCo transition-metal riboswitch bound to cobalt

Classification:

RNA

Authors:

Furukawa, K., Ramesh, A., Zhou, Z., Weinberg, Z., Vallery, T., Winkler, W.C., Breaker, R.R.

Citation:

Bacterial riboswitches cooperatively bind Ni(2+) or Co(2+) ions and control expression of heavy metal transporters.
Mol.Cell 57 pp.1088 - 1098 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.6426Å R work:0.193R free:0.231

NDB ID:

NA3205

PDB ID:

4RDX 

Release:

2015-03-25

Title:

Strucutre of histidinyl-tRNA synthetase in complex with tRNA(His)

Classification:

LIGASE/RNA

Authors:

Tian, Q., Wang, C., Liu, Y., Xie, W.

Citation:

Structural basis for recognition of G-1-containing tRNA by histidyl-tRNA synthetase
Nucleic Acids Res. 43 pp.2980 - 2990 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.55Å R work:0.207R free:0.261

NDB ID:

NA3362

PDB ID:

4S3N 

Release:

2015-03-25

Title:

Crystal structure of human OAS3 domain I in complex with dsRNA

Classification:

Transferase/RNA

Authors:

Donovan, J., Whitney, G., Rath, S., Korennykh, A.

Citation:

Structural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3.
Proc.Natl.Acad.Sci.USA 112 pp.3949 - 3954 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.0Å R work:0.181R free:0.211

NDB ID:

4WKR

PDB ID:

4WKR 

Release:

2015-03-18

Title:

LaRP7 wrapping up the 3' hairpin of 7SK non-coding RNA (302-332)

Classification:

RNA-BINDING PROTEIN

Authors:

Uchikawa, E., Natchiar, K.S., Han, X., Proux, F., Roblin, P., Zhang, E., Durand, A., Klaholz, B.P., Dock-Bregeon, A.C.

Citation:

Structural insight into the mechanism of stabilization of the 7SK small nuclear RNA by LARP7.
Nucleic Acids Res. 43 pp.3373 - 3388 2015

Experiment:

X-RAY DIFFRACTION Resolution:3.2Å R work:0.22R free:0.273

NDB ID:

4XJN

PDB ID:

4XJN 

Release:

2015-03-18

Title:

Structure of the parainfluenza virus 5 nucleocapsid-RNA complex: an insight into paramyxovirus polymerase activity

Classification:

VIRAL PROTEIN/RNA

Authors:

Alayyoubi, M., Leser, G.P., Kors, C.A., Lamb, R.A.

Citation:

Structure of the paramyxovirus parainfluenza virus 5 nucleoprotein-RNA complex.
Proc.Natl.Acad.Sci.USA 112 pp.E1792 - E1799 2015

Experiment:

X-RAY DIFFRACTION Resolution:3.11Å R work:0.227R free:0.262

NDB ID:

4Y4O

PDB ID:

4Y4O 

Release:

2015-03-18

Title:

Crystal structure of the Thermus thermophilus 70S ribosome with rRNA modifications and bound to protein Y (YfiA) at 2.3A resolution

Classification:

RIBOSOME

Authors:

Polikanov, Y.S., Melnikov, S.V., Soll, D., Steitz, T.A.

Citation:

Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly.
Nat.Struct.Mol.Biol. 22 pp.342 - 344 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.3Å R work:0.206R free:0.246

NDB ID:

4Y4P

PDB ID:

4Y4P 

Release:

2015-03-18

Title:

Crystal structure of the Thermus thermophilus 70S ribosome with rRNA modifications and bound to mRNA and A-, P- and E-site tRNAs at 2.5A resolution

Classification:

RIBOSOME

Authors:

Polikanov, Y.S., Melnikov, S.V., Soll, D., Steitz, T.A.

Citation:

Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly.
Nat.Struct.Mol.Biol. 22 pp.342 - 344 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.5Å R work:0.23R free:0.28

NDB ID:

4YBB

PDB ID:

4YBB 

Release:

2015-03-18

Title:

High-resolution structure of the Escherichia coli ribosome

Classification:

RIBOSOME

Authors:

Noeske, J., Wasserman, M.R., Terry, D.S., Altman, R.B., Blanchard, S.C., Cate, J.H.

Citation:

High-resolution structure of the Escherichia coli ribosome.
Nat.Struct.Mol.Biol. 22 pp.336 - 341 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.1Å R work:0.218R free:0.233

NDB ID:

4P97

PDB ID:

4P97 

Release:

2015-03-04

Title:

Functional conservation despite structural divergence in ligand-responsive RNA switches

Classification:

RNA

Authors:

Boerneke, M.A., Dibrov, S.M., Gu, J., Wyles, D.L., Hermann, T.

Citation:

Functional conservation despite structural divergence in ligand-responsive RNA switches.
Proc.Natl.Acad.Sci.USA 111 pp.15952 - 15957 2014

Experiment:

X-RAY DIFFRACTION Resolution:1.86Å R work:0.212R free:0.196

NDB ID:

2MXY

PDB ID:

2MXY 

Release:

2015-02-25

Title:

Solution structure of hnRNP C RRM in complex with 5'-AUUUUUC-3' RNA

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Cienikova, Z., Damberger, F.F., Hall, J., Allain, F.H., Maris, C.

Citation:

Structural and mechanistic insights into poly(uridine) tract recognition by the hnRNP C RNA recognition motif.
J.Am.Chem.Soc. 136 pp.14536 - 14544 2014

Experiment:

SOLUTION NMR

NDB ID:

4X9E

PDB ID:

4X9E 

Release:

2015-02-25

Title:

DEOXYGUANOSINETRIPHOSPHATE TRIPHOSPHOHYDROLASE from Escherichia coli with two DNA effector molecules

Classification:

HYDROLASE/DNA

Authors:

Singh, D., Gawel, D., Itsko, M., Hochkoeppler, A., Krahn, J.M., London, R.E., Schaaper, R.M.

Citation:

Structure of Escherichia coli dGTP Triphosphohydrolase: A Hexameric Enzyme With DNA Effector Molecules.
J.Biol.Chem. pp. - 2015

Experiment:

X-RAY DIFFRACTION Resolution:3.1Å R work:0.166R free:0.222

NDB ID:

4XEJ

PDB ID:

4XEJ 

Release:

2015-02-25

Title:

IRES bound to bacterial Ribosome

Classification:

Ribosome

Authors:

Colussi, T.M., Costantino, D.A., Zhu, J., Donohue, J.P., Korostelev, A.A., Jaafar, Z.A., Plank, T.D., Noller, H.F., Kieft, J.S.

Citation:

Initiation of translation in bacteria by a structured eukaryotic IRES RNA.
Nature 519 pp.110 - 113 2015

Experiment:

X-RAY DIFFRACTION Resolution:3.8Å R work:0.246R free:0.284

NDB ID:

4PHY

PDB ID:

4PHY 

Release:

2015-02-18

Title:

Functional conservation despite structural divergence in ligand-responsive RNA switches

Classification:

RNA

Authors:

Boerneke, M.A., Dibrov, S.M., Gu, J., Wyles, D.L., Hermann, T.

Citation:

Functional conservation despite structural divergence in ligand-responsive RNA switches.
Proc.Natl.Acad.Sci.USA 111 pp.15952 - 15957 2014

Experiment:

X-RAY DIFFRACTION Resolution:3.1Å R work:0.214R free:0.267

NDB ID:

4WQS

PDB ID:

4WQS 

Release:

2015-02-18

Title:

Thermus thermophilus RNA polymerase backtracked complex

Classification:

TRANSFERASE/DNA/RNA

Authors:

Sekine, S.I., Murayama, Y., Svetlov, V., Nudler, E., Yokoyama, S.

Citation:

The Ratcheted and Ratchetable Structural States of RNA Polymerase Underlie Multiple Transcriptional Functions.
Mol.Cell 57 pp.408 - 421 2015

Experiment:

X-RAY DIFFRACTION Resolution:4.306Å R work:0.28R free:0.311

NDB ID:

4WTA

PDB ID:

4WTA 

Release:

2015-02-11

Title:

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH UDP, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-CAAAAUUU

Classification:

Transferase/RNA

Authors:

Appleby, T.C., Perry, J.K., Murakami, E., Barauskas, O., Feng, J., Cho, A., Fox, D., Wetmore, D.R., McGrath, M.E., Ray, A.S., Sofia, M.J., Swaminathan, S., Edwards, T.E.

Citation:

Structural basis for RNA replication by the hepatitis C virus polymerase.
Science 347 pp.771 - 775 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.8Å R work:0.175R free:0.224

NDB ID:

4WTC

PDB ID:

4WTC 

Release:

2015-02-11

Title:

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH CDP, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-AGAAAUUU

Classification:

Transferase/RNA

Authors:

Appleby, T.C., Perry, J.K., Murakami, E., Barauskas, O., Feng, J., Cho, A., Fox, D., Wetmore, D.R., McGrath, M.E., Ray, A.S., Sofia, M.J., Swaminathan, S., Edwards, T.E.

Citation:

Structural basis for RNA replication by the hepatitis C virus polymerase.
Science 347 pp.771 - 775 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.75Å R work:0.178R free:0.229

NDB ID:

4WTD

PDB ID:

4WTD 

Release:

2015-02-11

Title:

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH ADP, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-AUAAAUUU

Classification:

Transferase/RNA

Authors:

Appleby, T.C., Perry, J.K., Murakami, E., Barauskas, O., Feng, J., Cho, A., Fox, D., Wetmore, D.R., McGrath, M.E., Ray, A.S., Sofia, M.J., Swaminathan, S., Edwards, T.E.

Citation:

Structural basis for RNA replication by the hepatitis C virus polymerase.
Science 347 pp.771 - 775 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.7Å R work:0.181R free:0.223

NDB ID:

4WTE

PDB ID:

4WTE 

Release:

2015-02-11

Title:

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH GDP, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-ACAAAUUU

Classification:

Transferase/RNA

Authors:

Appleby, T.C., Perry, J.K., Murakami, E., Barauskas, O., Feng, J., Cho, A., Fox, D., Wetmore, D.R., McGrath, M.E., Ray, A.S., Sofia, M.J., Swaminathan, S., Edwards, T.E.

Citation:

Structural basis for RNA replication by the hepatitis C virus polymerase.
Science 347 pp.771 - 775 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.9Å R work:0.18R free:0.218

NDB ID:

4WTF

PDB ID:

4WTF 

Release:

2015-02-11

Title:

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH GS-639475, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-CAAAAUUU

Classification:

Transferase/RNA

Authors:

Appleby, T.C., Perry, J.K., Murakami, E., Barauskas, O., Feng, J., Cho, A., Fox, D., Wetmore, D.R., McGrath, M.E., Ray, A.S., Sofia, M.J., Swaminathan, S., Edwards, T.E.

Citation:

Structural basis for RNA replication by the hepatitis C virus polymerase.
Science 347 pp.771 - 775 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.65Å R work:0.187R free:0.233

NDB ID:

4WTG

PDB ID:

4WTG 

Release:

2015-02-11

Title:

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH SOFOSBUVIR DIPHOSPHATE GS-607596, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-CAAAAUUU

Classification:

Transferase/RNA

Authors:

Appleby, T.C., Perry, J.K., Murakami, E., Barauskas, O., Feng, J., Cho, A., Fox, D., Wetmore, D.R., McGrath, M.E., Ray, A.S., Sofia, M.J., Swaminathan, S., Edwards, T.E.

Citation:

Structural basis for RNA replication by the hepatitis C virus polymerase.
Science 347 pp.771 - 775 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.9Å R work:0.179R free:0.231

NDB ID:

4WTI

PDB ID:

4WTI 

Release:

2015-02-11

Title:

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS IN COMPLEX WITH RNA TEMPLATE 5'-ACGG, RNA PRIMER 5'-PCC, MN2+, AND GDP

Classification:

Transferase/RNA

Authors:

Appleby, T.C., Perry, J.K., Murakami, E., Barauskas, O., Feng, J., Cho, A., Fox, D., Wetmore, D.R., McGrath, M.E., Ray, A.S., Sofia, M.J., Swaminathan, S., Edwards, T.E.

Citation:

Structural basis for RNA replication by the hepatitis C virus polymerase.
Science 347 pp.771 - 775 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.8Å R work:0.18R free:0.233

NDB ID:

4WTJ

PDB ID:

4WTJ 

Release:

2015-02-11

Title:

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS IN COMPLEX WITH RNA TEMPLATE 5'-AUCC, RNA PRIMER 5'-PGG, MN2+, AND ADP

Classification:

Transferase/RNA

Authors:

Appleby, T.C., Perry, J.K., Murakami, E., Barauskas, O., Feng, J., Cho, A., Fox, D., Wetmore, D.R., McGrath, M.E., Ray, A.S., Sofia, M.J., Swaminathan, S., Edwards, T.E.

Citation:

Structural basis for RNA replication by the hepatitis C virus polymerase.
Science 347 pp.771 - 775 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.2Å R work:0.175R free:0.21

NDB ID:

4WTK

PDB ID:

4WTK 

Release:

2015-02-11

Title:

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS IN COMPLEX WITH RNA TEMPLATE 5'-AGCC, RNA PRIMER 5'-PGG, MN2+, AND CDP

Classification:

Transferase/RNA

Authors:

Appleby, T.C., Perry, J.K., Murakami, E., Barauskas, O., Feng, J., Cho, A., Fox, D., Wetmore, D.R., McGrath, M.E., Ray, A.S., Sofia, M.J., Swaminathan, S., Edwards, T.E.

Citation:

Structural basis for RNA replication by the hepatitis C virus polymerase.
Science 347 pp.771 - 775 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.5Å R work:0.184R free:0.224

NDB ID:

4WTL

PDB ID:

4WTL 

Release:

2015-02-11

Title:

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS IN COMPLEX WITH RNA TEMPLATE 5'-UACC, RNA PRIMER 5'-PGG, MN2+, AND UDP

Classification:

Transferase/RNA

Authors:

Appleby, T.C., Perry, J.K., Murakami, E., Barauskas, O., Feng, J., Cho, A., Fox, D., Wetmore, D.R., McGrath, M.E., Ray, A.S., Sofia, M.J., Swaminathan, S., Edwards, T.E.

Citation:

Structural basis for RNA replication by the hepatitis C virus polymerase.
Science 347 pp.771 - 775 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.0Å R work:0.202R free:0.234

NDB ID:

4WTM

PDB ID:

4WTM 

Release:

2015-02-11

Title:

CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS IN COMPLEX WITH RNA TEMPLATE 5'-UAGG, RNA PRIMER 5'-PCC, MN2+, AND UDP

Classification:

Transferase/RNA

Authors:

Appleby, T.C., Perry, J.K., Murakami, E., Barauskas, O., Feng, J., Cho, A., Fox, D., Wetmore, D.R., McGrath, M.E., Ray, A.S., Sofia, M.J., Swaminathan, S., Edwards, T.E.

Citation:

Structural basis for RNA replication by the hepatitis C virus polymerase.
Science 347 pp.771 - 775 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.15Å R work:0.185R free:0.216

NDB ID:

4X4N

PDB ID:

4X4N 

Release:

2015-02-11

Title:

Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix

Classification:

transferase/RNA

Authors:

Kuhn, C.D., Wilusz, J.E., Zheng, Y., Beal, P.A., Joshua-Tor, L.

Citation:

On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme.
Cell 160 pp.644 - 658 2015

Experiment:

X-RAY DIFFRACTION Resolution:2.953Å R work:0.191R free:0.248

NDB ID:

4X4O

PDB ID:

4X4O 

Release:

2015-02-11

Title:

Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix and CTP

Classification:

RNA BINDING PROTEIN

Authors:

Kuhn, C.D., Wilusz, J.E., Zheng, Y., Beal, P.A., Joshua-Tor, L.

Citation:

On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme.
Cell 160 pp.644 - 658 2015

Experiment:

X-RAY DIFFRACTION Resolution:3.201Å R work:0.209R free:0.251