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As of 20-Mar-2019 number of released structures: 10085
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Polymer Type: All + RNA Type: All + Protein Function: All + Experimental Method: All + RNA Sequence Type: All RNA Sequence

Results: 4931  Download results as an excel file       Gallery view

NDB ID:

5ZX2

PDB ID:

5ZX2 

Release:

2019-03-20

Title:

Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ECF sigma factor sigma H and 7nt RNA

Classification:

TRANSCRIPTION/DNA/RNA

Authors:

Li, L., Fang, C., Zhuang, N., Zhang, Y.

Citation:

Structural basis for transcription initiation by bacterial ECF sigma factors
Nat Commun pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.8Å R work:0.219R free:0.254

NDB ID:

6ND5

PDB ID:

6ND5 

Release:

2019-03-20

Title:

Crystal structure of the Thermus thermophilus 70S ribosome in complex with chloramphenicol and bound to mRNA and A-, P-, and E-site tRNAs at 2.60A resolution

Classification:

RIBOSOME/ANTIBIOTIC

Authors:

Svetlov, M.S., Plessa, E., Chen, C.W., Bougas, A., Krokidis, M.G., Dinos, G.P., Polikanov, Y.

Citation:

High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition.
RNA pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.6Å R work:0.229R free:0.276

NDB ID:

6A4E

PDB ID:

6A4E 

Release:

2019-03-13

Title:

Two linked uridine bound Oligoribonuclease (ORN) from Colwellia psychrerythraea strain 34H

Classification:

HYDROLASE

Authors:

Lee, C.W., Park, S.H., Jeong, C.S., Cha, S.S., Park, H., Lee, J.H.

Citation:

Structural basis of small RNA hydrolysis by oligoribonuclease (CpsORN) from Colwellia psychrerythraea strain 34H.
Sci Rep 9 pp.2649 - 2649 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.45Å R work:0.236R free:0.275

NDB ID:

6AAY

PDB ID:

6AAY 

Release:

2019-03-13

Title:

the Cas13b binary complex

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Zhang, B., Ye, W.W., Ye, Y.M., Zhou, H., Saeed, A.F.U.H., Chen, J., Lin, J.Y., Perculija, V., Chen, Q., Chen, C.J., Chang, M.X., Choudhary, M.I., Ouyang, S.Y.

Citation:

Structural insights into Cas13b-guided CRISPR RNA maturation and recognition.
Cell Res. 28 pp.1198 - 1201 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.79Å R work:0.221R free:0.276

NDB ID:

5ZTM

PDB ID:

5ZTM 

Release:

2019-03-06

Title:

Crystal structure of MLE dsRBDs in complex with roX2 (R2H1)

Classification:

HYDROLASE/RNA

Authors:

Lv, M.Q., Yao, Y.X., Li, F.D., Xu, L., Yang, L.N., Gong, Q.G., Xu, Y.Z., Shi, Y.Y., Fan, Y.J., Tang, Y.J.

Citation:

Structural insights reveal the specific recognition of roX RNA by the dsRNA-binding domains of the RNA helicase MLE and its indispensable role in dosage compensation in Drosophila.
Nucleic Acids Res. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.899Å R work:0.19R free:0.243

NDB ID:

6I3P

PDB ID:

6I3P 

Release:

2019-03-06

Title:

Crystal structure of DEAH-box ATPase Prp22 with bound ssRNA

Classification:

HYDROLASE

Authors:

Hamann, F., Enders, M., Ficner, R.

Citation:

Structural basis for RNA translocation by DEAH-box ATPases.
Nucleic Acids Res. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.75Å R work:0.221R free:0.253

NDB ID:

6QIC

PDB ID:

6QIC 

Release:

2019-03-06

Title:

Crystal structure of DEAH-box ATPase Prp22-S837A with bound ssRNA

Classification:

HYDROLASE

Authors:

Hamann, F., Enders, M., Ficner, R.

Citation:

Structural basis for RNA translocation by DEAH-box ATPases.
Nucleic Acids Res. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.7Å R work:0.212R free:0.261

NDB ID:

6BY1

PDB ID:

6BY1 

Release:

2019-02-27

Title:

E. coli pH03H9 complex

Classification:

RIBOSOME

Authors:

Amiri, H., Noller, H.F.

Citation:

Structural evidence for product stabilization by the ribosomal mRNA helicase.
RNA 25 pp.364 - 375 2019

Experiment:

X-RAY DIFFRACTION Resolution:3.94Å R work:0.248R free:0.269

NDB ID:

6NDK

PDB ID:

6NDK 

Release:

2019-02-27

Title:

Structure of ASLSufA6 A37.5 bound to the 70S A site

Classification:

RIBOSOME

Authors:

Nguyen, H., Hoffer, E.D., Dunham, C.M.

Citation:

Structure of ASLSufA6 A37.5 bound to the 70S A site
to be published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:3.64Å R work:0.208R free:0.249

NDB ID:

6D06

PDB ID:

6D06 

Release:

2019-02-20

Title:

Human ADAR2d E488Y mutant complexed with dsRNA containing an abasic site opposite the edited base

Classification:

HYDROLASE/RNA

Authors:

Monteleone, L.R., Matthews, M.M., Palumbo, C.M., Thomas, J.M., Zheng, Y., Chiang, Y., Fisher, A.J., Beal, P.A.

Citation:

A Bump-Hole Approach for Directed RNA Editing.
Cell Chem Biol 26 pp.269 - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.55Å R work:0.19R free:0.255

NDB ID:

6DTD

PDB ID:

6DTD 

Release:

2019-02-20

Title:

High-resolution crystal structure of Cas13b from Prevotella buccae

Classification:

HYDROLASE/RNA

Authors:

Slaymaker, I.M.S., Zhang, F.Z.

Citation:

High-resolution crystal structure of Cas13b from Prevotella buccae
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.65Å R work:0.153R free:0.185

NDB ID:

6DV9

PDB ID:

6DV9 

Release:

2019-02-20

Title:

Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 4nt spacer

Classification:

TRANSFERASE/DNA/RNA

Authors:

Lin, W., Mandal, S., Degen, D., Cho, M.S., Feng, Y., Das, K., Ebright, R.H.

Citation:

Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun 10 pp.710 - 710 2019

Experiment:

X-RAY DIFFRACTION Resolution:3.8Å R work:0.184R free:0.231

NDB ID:

6DVB

PDB ID:

6DVB 

Release:

2019-02-20

Title:

Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 5nt spacer

Classification:

TRANSFERASE/DNA/RNA

Authors:

Lin, W., Mandal, S., Degen, D., Cho, M.S., Feng, Y., Das, K., Ebright, R.H.

Citation:

Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun 10 pp.710 - 710 2019

Experiment:

X-RAY DIFFRACTION Resolution:3.8Å R work:0.201R free:0.24

NDB ID:

6DVC

PDB ID:

6DVC 

Release:

2019-02-20

Title:

Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 6nt spacer

Classification:

TRANSFERASE/DNA/RNA

Authors:

Lin, W., Mandal, S., Degen, D., Cho, M.S., Feng, Y., Das, K., Ebright, R.H.

Citation:

Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun 10 pp.710 - 710 2019

Experiment:

X-RAY DIFFRACTION Resolution:3.3Å R work:0.197R free:0.234

NDB ID:

6E0O

PDB ID:

6E0O 

Release:

2019-02-20

Title:

Structure of Elizabethkingia meningoseptica CdnE cyclic dinucleotide synthase with pppA[3'-5']pA

Classification:

TRANSFERASE/RNA

Authors:

Whiteley, A.T., Eaglesham, J.B., de Oliveira Mann, C.C., Morehouse, B.R., Lowey, B., Nieminen, E.A., Danilchanka, O., King, D.S., Lee, A.S.Y., Mekalanos, J.J., Kranzusch, P.J.

Citation:

Bacterial cGAS-like enzymes synthesize diverse nucleotide signals.
Nature pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.25Å R work:0.142R free:0.163

NDB ID:

6G99

PDB ID:

6G99 

Release:

2019-02-20

Title:

Solution structure of FUS-ZnF bound to UGGUG

Classification:

RNA BINDING PROTEIN

Authors:

Loughlin, F.E., Lukavsky, P.J., Kazeeva, T., Reber, S., Hock, E.M., Colombo, M., Von Schroetter, C., Pauli, P., Clery, A., Muhlemann, O., Polymenidou, M., Ruepp, M.D., Allain, F.H.

Citation:

The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity.
Mol. Cell 73 pp.490 - 504.e6 2019

Experiment:

SOLUTION NMR

NDB ID:

6GBM

PDB ID:

6GBM 

Release:

2019-02-20

Title:

Solution structure of FUS-RRM bound to stem-loop RNA

Classification:

RNA BINDING PROTEIN

Authors:

Loughlin, F.E., Lukavsky, P.J., Kazeeva, T., Reber, S., Hock, E.M., Colombo, M., Von Schroetter, C., Pauli, P., Clery, A., Muhlemann, O., Polymenidou, M., Ruepp, M.D., Allain, F.H.

Citation:

The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity.
Mol. Cell 73 pp.490 - 504.e6 2019

Experiment:

SOLUTION NMR

NDB ID:

6HBT

PDB ID:

6HBT 

Release:

2019-02-20

Title:

The structure of the G. violaceus guanidine II riboswitch P2 stem-loop with arcaine

Classification:

RNA

Authors:

Huang, L., Wang, J., Wilson, T.J., Lilley, D.M.J.

Citation:

Structure-guided design of a high affinity ligand for a riboswitch.
RNA pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.66Å R work:0.206R free:0.213

NDB ID:

6HBX

PDB ID:

6HBX 

Release:

2019-02-20

Title:

The structure of the G. violaceus guanidine II riboswitch P2 stem-loop with ethylguanidine

Classification:

RNA

Authors:

Huang, L., Wang, J., Wilson, T.J., Lilley, D.M.J.

Citation:

Structure-guided design of a high affinity ligand for a riboswitch.
RNA pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.54Å R work:0.189R free:0.23

NDB ID:

6HC5

PDB ID:

6HC5 

Release:

2019-02-20

Title:

The structure of the G. violaceus guanidine II riboswitch P2 stem-loop with audouine

Classification:

RNA

Authors:

Huang, L., Wang, J., Wilson, T.J., Lilley, D.M.J.

Citation:

Structure-guided design of a high affinity ligand for a riboswitch.
RNA pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.413Å R work:0.175R free:0.198

NDB ID:

6HHQ

PDB ID:

6HHQ 

Release:

2019-02-20

Title:

Crystal structure of compound C45 bound to the yeast 80S ribosome

Classification:

RIBOSOME

Authors:

Pellegrino, S., Meyer, M., Konst, Z.A., Holm, M., Voora, V.K., Kashinskaya, D., Zanette, C., Mobley, D.L., Yusupova, G., Vanderwal, C.D., Blanchard, S.C., Yusupov, M.

Citation:

Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome.
Nucleic Acids Res. pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:3.1Å R work:0.216R free:0.264

NDB ID:

6M7K

PDB ID:

6M7K 

Release:

2019-02-20

Title:

Structure of mouse RECON (AKR1C13) in complex with cyclic AMP-AMP-GMP (cAAG)

Classification:

OXIDOREDUCTASE

Authors:

Whiteley, A.T., Eaglesham, J.B., de Oliveira Mann, C.C., Morehouse, B.R., Lowey, B., Nieminen, E.A., Danilchanka, O., King, D.S., Lee, A.S.Y., Mekalanos, J.J., Kranzusch, P.J.

Citation:

Bacterial cGAS-like enzymes synthesize diverse nucleotide signals.
Nature pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.1Å R work:0.142R free:0.157

NDB ID:

6ND6

PDB ID:

6ND6 

Release:

2019-02-20

Title:

Crystal structure of the Thermus thermophilus 70S ribosome in complex with erythromycin and bound to mRNA and A-, P-, and E-site tRNAs at 2.85A resolution

Classification:

RIBOSOME/ANTIBIOTIC

Authors:

Svetlov, M.S., Plessa, E., Chen, C.W., Bougas, A., Krokidis, M.G., Dinos, G.P., Polikanov, Y.

Citation:

High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition.
RNA pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.85Å R work:0.249R free:0.304

NDB ID:

6N8F

PDB ID:

6N8F 

Release:

2019-02-13

Title:

RNA Duplex containing the internal loop 5'-GCUU/3'-UUCG

Classification:

RNA

Authors:

Berger, K.D., Kennedy, S.D., Turner, D.H.

Citation:

Nuclear Magnetic Resonance Reveals That GU Base Pairs Flanking Internal Loops Can Adopt Diverse Structures.
Biochemistry 58 pp.1094 - 1108 2019

Experiment:

SOLUTION NMR

NDB ID:

6N8H

PDB ID:

6N8H 

Release:

2019-02-13

Title:

RNA Duplex containing the internal loop 5'-GCAU/3'-UACG

Classification:

RNA

Authors:

Berger, K.D., Kennedy, S.D., Turner, D.H.

Citation:

Nuclear Magnetic Resonance Reveals That GU Base Pairs Flanking Internal Loops Can Adopt Diverse Structures.
Biochemistry 58 pp.1094 - 1108 2019

Experiment:

SOLUTION NMR

NDB ID:

6N8I

PDB ID:

6N8I 

Release:

2019-02-13

Title:

RNA Duplex containing the internal loop 5'-UUCG/3'-GCUU

Classification:

RNA

Authors:

Berger, K.D., Kennedy, S.D., Turner, D.H.

Citation:

Nuclear Magnetic Resonance Reveals That GU Base Pairs Flanking Internal Loops Can Adopt Diverse Structures.
Biochemistry 58 pp.1094 - 1108 2019

Experiment:

SOLUTION NMR

NDB ID:

5Z71

PDB ID:

5Z71 

Release:

2019-01-30

Title:

Crystal structure of the Homo Sapiens cytoplasmic ribosomal decoding site in complex with G418 (P21212 form)

Classification:

RNA

Authors:

Kanazawa, H., Tsurumi, N., Baasov, T., Kondo, J.

Citation:

Structural studies of aminoglycoside antibiotics G418 and its derivatives with readthrough activities
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.5Å R work:0.269R free:0.305

NDB ID:

5ZSA

PDB ID:

5ZSA 

Release:

2019-01-30

Title:

Crystal structure of monkey TLR7 in complex with IMDQ and UUUUUU

Classification:

IMMUNE SYSTEM

Authors:

Shimizu, T.

Citation:

To be published
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.5Å R work:0.198R free:0.249

NDB ID:

5ZSB

PDB ID:

5ZSB 

Release:

2019-01-30

Title:

Crystal structure of monkey TLR7 in complex with IMDQ and AAUUAA

Classification:

IMMUNE SYSTEM

Authors:

Shimizu, T.

Citation:

To be published
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.7Å R work:0.191R free:0.251

NDB ID:

5ZSC

PDB ID:

5ZSC 

Release:

2019-01-30

Title:

Crystal structure of monkey TLR7 in complex with IMDQ and CCUUCC

Classification:

IMMUNE SYSTEM

Authors:

Shimizu, T.

Citation:

To be published
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.2Å R work:0.191R free:0.227

NDB ID:

5ZSD

PDB ID:

5ZSD 

Release:

2019-01-30

Title:

Crystal structure of monkey TLR7 in complex with IMDQ and GGUUGG

Classification:

IMMUNE SYSTEM

Authors:

Shimizu, T.

Citation:

To be published
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.603Å R work:0.19R free:0.233

NDB ID:

5ZSE

PDB ID:

5ZSE 

Release:

2019-01-30

Title:

Crystal structure of monkey TLR7 in complex with IMDQ and GGUCCC

Classification:

IMMUNE SYSTEM

Authors:

Shimizu, T.

Citation:

To be published
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.201Å R work:0.195R free:0.232

NDB ID:

5ZSL

PDB ID:

5ZSL 

Release:

2019-01-30

Title:

Crystal structure of monkey TLR7 in complex with GGUUGG

Classification:

IMMUNE SYSTEM

Authors:

Shimizu, T.

Citation:

To be published
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.3Å R work:0.217R free:0.258

NDB ID:

5ZSM

PDB ID:

5ZSM 

Release:

2019-01-30

Title:

Crystal structure of monkey TLR7 in complex with GGUCCC

Classification:

IMMUNE SYSTEM

Authors:

Shimizu, T.

Citation:

To be published
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.5Å R work:0.228R free:0.273

NDB ID:

5ZSN

PDB ID:

5ZSN 

Release:

2019-01-30

Title:

Crystal structure of monkey TLR7 in complex with AAUUAA

Classification:

IMMUNE SYSTEM

Authors:

Shimizu, T.

Citation:

To be published
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.4Å R work:0.202R free:0.245

NDB ID:

6FHH

PDB ID:

6FHH 

Release:

2019-01-30

Title:

Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 22-mer modified Pol II CTD peptide with serine 5 thiophosphorylated.

Classification:

VIRAL PROTEIN

Authors:

Claron, M., Lukarska, M., Uhrig, U., Sehr, P., Drncova, P., Lewis, J.D., Will, D.W., Cusack, S.

Citation:

Towards New Anti-Influenza Therapeutics: Structure-Activity Relationships in the Interaction between Heterotrimeric Influenza Polymerase and Pol II C-terminal domain
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.7Å R work:0.212R free:0.257

NDB ID:

6FHI

PDB ID:

6FHI 

Release:

2019-01-30

Title:

Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 19-mer serine 5 phosphorylated Pol II CTD peptide with a truncated linker.

Classification:

VIRAL PROTEIN

Authors:

Claron, M., Lukarska, M., Uhrig, U., Sehr, P., Drncova, P., Lewis, J.D., Will, D.W., Cusack, S.

Citation:

Towards New Anti-Influenza Therapeutics: Structure-Activity Relationships in the Interaction between Heterotrimeric Influenza Polymerase and Pol II C-terminal domain
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.8Å R work:0.23R free:0.269

NDB ID:

6GC5

PDB ID:

6GC5 

Release:

2019-01-30

Title:

Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM

Classification:

RNA BINDING PROTEIN

Authors:

Ripin, N., Boudet, J., Duszczyk, M.M., Hinniger, A., Faller, M., Krepl, M., Gadi, A., Schneider, R.J., Sponer, J., Meisner-Kober, N.C., Allain, F.H.

Citation:

Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM.
Proc. Natl. Acad. Sci. U.S.A. 116 pp.2935 - 2944 2019

Experiment:

X-RAY DIFFRACTION Resolution:1.9Å R work:0.2R free:0.231

NDB ID:

6NOC

PDB ID:

6NOC 

Release:

2019-01-30

Title:

Crystal structure of FBF-2 repeat 5 mutant (C363A, R364Y) in complex with 8-nt RNA

Classification:

rna binding protein/rna

Authors:

Bhat, V.D., McCann, K.L., Wang, Y., Fonseca, D.R., Shukla, T., Alexander, J.C., Qiu, C., Wickens, M., Lo, T.W., Tanaka Hall, T.M., Campbell, Z.T.

Citation:

Engineering a conserved RNA regulatory protein repurposes its biological functionin vivo.
Elife 8 pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.849Å R work:0.219R free:0.277

NDB ID:

6NOD

PDB ID:

6NOD 

Release:

2019-01-30

Title:

Crystal structure of C. elegans PUF-8 in complex with RNA

Classification:

rna binding protein/rna

Authors:

Bhat, V.D., McCann, K.L., Wang, Y., Fonseca, D.R., Shukla, T., Alexander, J.C., Qiu, C., Wickens, M., Lo, T.W., Tanaka Hall, T.M., Campbell, Z.T.

Citation:

Engineering a conserved RNA regulatory protein repurposes its biological functionin vivo.
Elife 8 pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.547Å R work:0.229R free:0.285

NDB ID:

6NOF

PDB ID:

6NOF 

Release:

2019-01-30

Title:

Crystal structure of FBF-2 repeat 5 mutant (C363A, R364Y, Q367S) in complex with 8-nt RNA

Classification:

rna binding protein/rna

Authors:

Bhat, V.D., McCann, K.L., Wang, Y., Fonseca, D.R., Shukla, T., Alexander, J.C., Qiu, C., Wickens, M., Lo, T.W., Tanaka Hall, T.M., Campbell, Z.T.

Citation:

Engineering a conserved RNA regulatory protein repurposes its biological functionin vivo.
Elife 8 pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.251Å R work:0.164R free:0.222

NDB ID:

6NOH

PDB ID:

6NOH 

Release:

2019-01-30

Title:

Crystal structure of FBF-2 repeat 5 mutant (C363S, R364Y, Q367S) in complex with 8-nt RNA

Classification:

rna binding protein/rna

Authors:

Bhat, V.D., McCann, K.L., Wang, Y., Fonseca, D.R., Shukla, T., Alexander, J.C., Qiu, C., Wickens, M., Lo, T.W., Tanaka Hall, T.M., Campbell, Z.T.

Citation:

Engineering a conserved RNA regulatory protein repurposes its biological functionin vivo.
Elife 8 pp. - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.249Å R work:0.158R free:0.205

NDB ID:

6I1K

PDB ID:

6I1K 

Release:

2019-01-23

Title:

Crystal structure of catalytically inactive FnCas12a in complex with a crRNA guide and a dsDNA target

Classification:

HYDROLASE

Authors:

Swarts, D.C., Jinek, M.

Citation:

Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12a.
Mol. Cell 73 pp.589 - 600.e4 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.65Å R work:0.248R free:0.263

NDB ID:

6I1L

PDB ID:

6I1L 

Release:

2019-01-23

Title:

Crystal structure of FnCas12a in complex with a crRNA guide and ssDNA target

Classification:

HYDROLASE

Authors:

Swarts, D.C., Jinek, M.

Citation:

Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12a.
Mol. Cell 73 pp.589 - 600.e4 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.98Å R work:0.203R free:0.231

NDB ID:

6IFO

PDB ID:

6IFO 

Release:

2019-01-23

Title:

Crystal structure of AcrIIA2-SpyCas9-sgRNA ternary complex

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Liu, L., Yin, M., Wang, M., Wang, Y.

Citation:

Phage AcrIIA2 DNA Mimicry: Structural Basis of the CRISPR and Anti-CRISPR Arms Race.
Mol. Cell 73 pp.611 - 620.e3 2019

Experiment:

X-RAY DIFFRACTION Resolution:3.313Å R work:0.222R free:0.268

NDB ID:

5ZC9

PDB ID:

5ZC9 

Release:

2019-01-16

Title:

Crystal structure of the human eIF4A1-ATP analog-RocA-polypurine RNA complex

Classification:

TRANSLATION/RNA

Authors:

Iwasaki, S., Iwasaki, W., Takahashi, M., Sakamoto, A., Watanabe, C., Shichino, Y., Floor, S.N., Fujiwara, K., Mito, M., Dodo, K., Sodeoka, M., Imataka, H., Honma, T., Fukuzawa, K., Ito, T., Ingolia, N.T.

Citation:

The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA.
Mol. Cell 73 pp.738 - 2019

Experiment:

X-RAY DIFFRACTION Resolution:2.0Å R work:0.192R free:0.23

NDB ID:

6BJG

PDB ID:

6BJG 

Release:

2019-01-16

Title:

CIRV p19 mutant T111H in complex with siRNA

Classification:

RNA BINDING PROTEIN

Authors:

Foss, D.V., Schirle, N.T., MacRae, I.J., Pezacki, J.P.

Citation:

Structural examination of p19 mutants with high affinity for human miRNA-122
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.29Å R work:0.212R free:0.257

NDB ID:

6BJH

PDB ID:

6BJH 

Release:

2019-01-16

Title:

CIRV p19 mutant T111S in complex with siRNA

Classification:

RNA BINDING PROTEIN

Authors:

Foss, D.V., Schirle, N.T., MacRae, I.J., Pezacki, J.P.

Citation:

Structural examination of p19 mutants with high affinity for human miRNA-122.
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.58Å R work:0.224R free:0.277

NDB ID:

6BJV

PDB ID:

6BJV 

Release:

2019-01-16

Title:

CIRV p19 protein in complex with siRNA

Classification:

RNA BINDING PROTEIN

Authors:

Foss, D.V., Schirle, N.T., MacRae, I.J., Pezacki, J.P.

Citation:

Structural examination of p19 mutants with high affinity for human miRNA-122
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.198Å R work:0.259R free:0.297

NDB ID:

6C27

PDB ID:

6C27 

Release:

2019-01-09

Title:

SAM-III riboswitch ON-state

Classification:

RNA

Authors:

Price, I.R., Grigg, J.C., Martell, D.J., Ding, F., Peng, C., Ke, A.

Citation:

Evidence for two-tiered conformation selection in the SAM-III riboswitch
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:3.601Å R work:0.21R free:0.243

Equivalence Class: 

NR_all_86306.1 

Eq. Class Rep:

6C27