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As of 21-Jun-2017 number of released structures: 8945
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Polymer Type: All + RNA Type: All + Protein Function: All + Experimental Method: All + RNA Sequence Type: All RNA Sequence

Results: 3295  Download results as an excel file       Gallery view

NDB ID:

 5LQO

PDB ID:

5LQO 

Release:

2017-06-21

Title:

RNA duplex has central consecutive GA pairs flanked by G-C basepairs

Classification:

RNA

Authors:

Huang, L., Lilley, D.M.J.

Citation:

Control of box C/D snoRNP assembly by N6-methylation of adenine
Embo Rep. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.87Å R work:0.245R free:0.255

NDB ID:

 5LQT

PDB ID:

5LQT 

Release:

2017-06-21

Title:

RNA duplex has central consecutive GA pairs flanked by G-C basepairs

Classification:

RNA

Authors:

Huang, L., Lilley, D.M.J.

Citation:

Control of box C/D snoRNP assembly by N6-methylation of adenine
Embo Rep. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.5Å R work:0.219R free:0.227

NDB ID:

 5LR3

PDB ID:

5LR3 

Release:

2017-06-21

Title:

RNA duplex has central consecutive GA pairs flanked by G-U basepairs

Classification:

RNA

Authors:

Huang, L., Lilley, D.M.J.

Citation:

Control of box C/D snoRNP assembly by N6-methylation of adenine
Embo Rep. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.65Å R work:0.247R free:0.265

NDB ID:

 5LR4

PDB ID:

5LR4 

Release:

2017-06-21

Title:

RNA duplex has central consecutive GA pairs flanked by G-U basepairs with a methyl group on the adenine N6

Classification:

RNA

Authors:

Huang, L., Lilley, D.M.J.

Citation:

Control of box C/D snoRNP assembly by N6-methylation of adenine
Embo Rep. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.8Å R work:0.269R free:0.288

NDB ID:

 5LR5

PDB ID:

5LR5 

Release:

2017-06-21

Title:

N6-methyladenine is accommodated in a conventional A-U basepair

Classification:

RNA

Authors:

Huang, L., Lilley, D.M.J.

Citation:

Control of box C/D snoRNP assembly by N6-methylation of adenine
Embo Rep. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.4Å R work:0.247R free:0.287

NDB ID:

 5MGA

PDB ID:

5MGA 

Release:

2017-06-21

Title:

Structure of the Cpf1 endonuclease R-loop complex after DNA cleavage

Classification:

HYDROLASE

Authors:

Stella, S., Alcon, P., Montoya, G.

Citation:

Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage.
Nature pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:3.0Å R work:0.241R free:0.265

NDB ID:

 5V1K

PDB ID:

5V1K 

Release:

2017-06-21

Title:

Structure of R-GNA dodecamer

Classification:

RNA

Authors:

Schlegel, M.K., Foster, D.J., Kel'in, A.V., Zlatev, I., Bisbe, A., Jayaraman, M., Lackey, J.G., Rajeev, K.G., Charisse, K., Harp, J., Pallan, P.S., Maier, M.A., Egli, M., Manoharan, M.

Citation:

Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA.
J. Am. Chem. Soc. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.18Å R work:0.167R free:0.224

NDB ID:

 5N9G

PDB ID:

5N9G 

Release:

2017-06-14

Title:

TFIIIB -TBP/Brf2/DNA and SANT domain of Bdp1-

Classification:

TRANSCRIPTION

Authors:

Gouge, J., Vannini, A., Guthertz, N.

Citation:

Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA Polymerase III transcription initiation
To Be Published pp. - 0

Experiment:

 X-RAY DIFFRACTION Resolution:2.7Å R work:0.194R free:0.233

NDB ID:

 5NFV

PDB ID:

5NFV 

Release:

2017-06-14

Title:

Crystal structure of catalytically inactive FnCas12 mutant bound to an R-loop structure containing a pre-crRNA mimic and full-length DNA target

Classification:

HYDROLASE

Authors:

Swarts, D.C., van der Oost, J., Jinek, M.

Citation:

Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.
Mol. Cell 66 pp.221 - 233.e4 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.501Å R work:0.205R free:0.237

NDB ID:

 5NG6

PDB ID:

5NG6 

Release:

2017-06-14

Title:

Crystal structure of FnCas12a bound to a crRNA

Classification:

HYDROLASE

Authors:

Swarts, D.C., van der Oost, J., Jinek, M.

Citation:

Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.
Mol. Cell 66 pp.221 - 233.e4 2017

Experiment:

 X-RAY DIFFRACTION Resolution:3.342Å R work:0.238R free:0.258

NDB ID:

 5UZZ

PDB ID:

5UZZ 

Release:

2017-06-14

Title:

Structure of wild type pre-miR21 apical loop

Classification:

TRANSPORT PROTEIN/RNA

Authors:

Shortridge, M.D., Walker, M.J., Pavelitz, T., Chen, Y., Yang, W., Varani, G.

Citation:

A Macrocyclic Peptide Ligand Binds the Oncogenic MicroRNA-21 Precursor and Suppresses Dicer Processing.
ACS Chem. Biol. pp. - 2017

Experiment:

 SOLUTION NMR

NDB ID:

 5V1L

PDB ID:

5V1L 

Release:

2017-06-14

Title:

Structure of S-GNA dodecamer

Classification:

RNA

Authors:

Schlegel, M.K., Foster, D.J., Kel'in, A.V., Zlatev, I., Bisbe, A., Jayaraman, M., Lackey, J.G., Rajeev, K.G., Charisse, K., Harp, J., Pallan, P.S., Maier, M.A., Egli, M., Manoharan, M.

Citation:

Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA.
J. Am. Chem. Soc. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.2Å R work:0.133R free:0.152

NDB ID:

 5V2H

PDB ID:

5V2H 

Release:

2017-06-14

Title:

RNA octamer containing glycol nucleic acid, SgnT

Classification:

RNA

Authors:

Schlegel, M.K., Foster, D.J., Kel'in, A.V., Zlatev, I., Bisbe, A., Jayaraman, M., Lackey, J.G., Rajeev, K.G., Charisse, K., Harp, J., Pallan, P.S., Maier, M.A., Egli, M., Manoharan, M.

Citation:

Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA.
J. Am. Chem. Soc. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.08001Å R work:0.135R free:0.156

NDB ID:

 5XBL

PDB ID:

5XBL 

Release:

2017-06-14

Title:

Structure of nuclease in complex with associated protein

Classification:

HYDROLASE/RNA

Authors:

Dong, D., Guo, M., Wang, S., Zhu, Y., Wang, S., Xiong, Z., Yang, J., Xu, Z., Huang, Z.

Citation:

Structural basis of CRISPR-SpyCas9 inhibition by an anti-CRISPR protein
Nature pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:3.052Å R work:0.237R free:0.277

NDB ID:

 5XH6

PDB ID:

5XH6 

Release:

2017-06-14

Title:

Crystal structure of the Acidaminococcus sp. BV3L6 Cpf1 RVR variant in complex with crRNA and target DNA (TATA PAM)

Classification:

HYDROLASE/RNA/DNA

Authors:

Nishimasu, H., Yamano, T., Gao, L., Zhang, F., Ishitani, R., Nureki, O.

Citation:

Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1
Mol.Cell 67 pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.0Å R work:0.174R free:0.209

NDB ID:

 5XH7

PDB ID:

5XH7 

Release:

2017-06-14

Title:

Crystal structure of the Acidaminococcus sp. BV3L6 Cpf1 RR variant in complex with crRNA and target DNA (TCCA PAM)

Classification:

HYDROLASE/RNA/DNA

Authors:

Nishimasu, H., Yamano, T., Gao, L., Zhang, F., Ishitani, R., Nureki, O.

Citation:

Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1
Mol.Cell 67 pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.0Å R work:0.182R free:0.214

NDB ID:

 5NEF

PDB ID:

5NEF 

Release:

2017-06-07

Title:

The structure of the G. violaceus guanidine II riboswitch P1 stem-loop with guanidine

Classification:

RNA

Authors:

Huang, L., Wang, J., Lilley, D.M.J.

Citation:

The Structure of the Guanidine-II Riboswitch.
Cell Chem Biol pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.91Å R work:0.202R free:0.257

NDB ID:

 5B63

PDB ID:

5B63 

Release:

2017-05-31

Title:

Crystal structures of E.coli arginyl-tRNA synthetase (ArgRS) in complex with substrate tRNA(Arg)

Classification:

LIGASE

Authors:

Zhou, M., Ye, S., Stephen, P., Zhang, R., Wang, E.D., Giege, R., Lin, S.X.

Citation:

Crystal structures of E.coli arginyl-tRNA synthetase (ArgRS) in complex with substrate tRNA(Arg)
To Be Published pp. - 0

Experiment:

 X-RAY DIFFRACTION Resolution:3.0Å R work:0.22R free:0.267

NDB ID:

 5NDH

PDB ID:

5NDH 

Release:

2017-05-31

Title:

The structure of the G. violaceus guanidine II riboswitch P2 stem-loop

Classification:

RNA

Authors:

Huang, L., Wang, J., Lilley, D.M.J.

Citation:

The Structure of the Guanidine-II Riboswitch.
Cell Chem Biol pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.81Å R work:0.206R free:0.222

NDB ID:

 5NDI

PDB ID:

5NDI 

Release:

2017-05-31

Title:

The structure of the E.coli guanidine II riboswitch P1 stem-loop

Classification:

RNA

Authors:

Huang, L., Wang, J., Lilley, D.M.J.

Citation:

The Structure of the Guanidine-II Riboswitch.
Cell Chem Biol pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.57Å R work:0.187R free:0.238

NDB ID:

 5NEO

PDB ID:

5NEO 

Release:

2017-05-31

Title:

The structure of the G. violaceus guanidine II riboswitch P1 stem-loop

Classification:

RNA

Authors:

Huang, L., Wang, J., Lilley, D.M.J.

Citation:

The Structure of the Guanidine-II Riboswitch.
Cell Chem Biol pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.69Å R work:0.215R free:0.23

NDB ID:

 5NEP

PDB ID:

5NEP 

Release:

2017-05-31

Title:

The structure of the G. violaceus guanidine II riboswitch P1 stem-loop with methylguanidine

Classification:

RNA

Authors:

Huang, L., Wang, J., Lilley, D.M.J.

Citation:

The Structure of the Guanidine-II Riboswitch.
Cell Chem Biol pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.6Å R work:0.206R free:0.217

NDB ID:

 5NEQ

PDB ID:

5NEQ 

Release:

2017-05-31

Title:

The structure of the G. violaceus guanidine II riboswitch P1 stem-loop with aminoguanidine

Classification:

RNA

Authors:

Huang, L., Wang, J., Lilley, D.M.J.

Citation:

The Structure of the Guanidine-II Riboswitch.
Cell Chem Biol pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.69Å R work:0.215R free:0.252

NDB ID:

 5NEX

PDB ID:

5NEX 

Release:

2017-05-31

Title:

The structure of the G. violaceus guanidine II riboswitch P1 stem-loop with agmatine

Classification:

RNA

Authors:

Huang, L., Wang, J., Lilley, D.M.J.

Citation:

The Structure of the Guanidine-II Riboswitch.
Cell Chem Biol pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.72Å R work:0.2R free:0.233

NDB ID:

 5NOM

PDB ID:

5NOM 

Release:

2017-05-31

Title:

The structure of the G. violaceus guanidine II riboswitch P1 stem-loop with guanidine

Classification:

RNA

Authors:

Huang, L., Wang, J., Lilley, D.M.J.

Citation:

The Structure of the Guanidine-II Riboswitch.
Cell Chem Biol pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.93Å R work:0.197R free:0.223

NDB ID:

 5UF3

PDB ID:

5UF3 

Release:

2017-05-31

Title:

Structure Effects of the Four-Adenine Loop of the Coliphage GA Replicase RNA Operator

Classification:

RNA

Authors:

Chang, A.T., Tran, M., Nikonowicz, E.P.

Citation:

Structure and Dynamics of the Tetra-A Loop and (A-A)-U Sequence Motif within the Coliphage GA Replicase RNA Operator.
Biochemistry 56 pp.2690 - 2700 2017

Experiment:

 SOLUTION NMR

NDB ID:

 5V3F

PDB ID:

5V3F 

Release:

2017-05-24

Title:

Co-crystal structure of the fluorogenic RNA Mango

Classification:

RNA

Authors:

Trachman, R.J., Demeshkina, N.A., Lau, M.W.L., Panchapakesan, S.S.S., Jeng, S.C.Y., Unrau, P.J., Ferre-D'Amare, A.R.

Citation:

Structural basis for high-affinity fluorophore binding and activation by RNA Mango.
Nat. Chem. Biol. pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.7Å R work:0.195R free:0.203

NDB ID:

 5VO8

PDB ID:

5VO8 

Release:

2017-05-24

Title:

X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter

Classification:

transcription/DNA/RNA

Authors:

Murakami, K.S., Shin, Y., Turnbough Jr., C.L., Molodtsov, V.

Citation:

X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter
To Be Published pp. - 0

Experiment:

 X-RAY DIFFRACTION Resolution:3.3Å R work:0.185R free:0.246

NDB ID:

 5UZT

PDB ID:

5UZT 

Release:

2017-05-10

Title:

Structure of wild type pre-miR21 apical loop

Classification:

RNA

Authors:

Shortridge, M.D., Walker, M.J., Pavelitz, T., Chen, Y., Varani, G.

Citation:

A macrocyclic peptide ligand binds the oncogenic microRNA-21 precursor and suppresses Dicer processing.
ACS Chem. Biol. pp. - 2017

Experiment:

 SOLUTION NMR

NDB ID:

 5HKV

PDB ID:

5HKV 

Release:

2017-05-03

Title:

The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with lincomycin

Classification:

RIBOSOME

Authors:

Yonath, A., Matzov, D., Eyal, Z., Ben Hamou, R., Zimmerman, E., Rozenberg, H., Bashan, A., Fridman, M.

Citation:

Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus
To Be Published pp. - 0

Experiment:

 X-RAY DIFFRACTION Resolution:3.66Å R work:0.187R free:0.233

NDB ID:

 5UX0

PDB ID:

5UX0 

Release:

2017-05-03

Title:

X-ray crystal structure of Marinitoga piezophila Argonaute in complex with 5' OH guide RNA and target DNA

Classification:

HYDROLASE/RNA/DNA

Authors:

Doxzen, K.W., Doudna, J.A.

Citation:

DNA recognition by an RNA-guided bacterial Argonaute.
PLoS ONE 12 pp.e0177097 - e0177097 2017

Experiment:

 X-RAY DIFFRACTION Resolution:3.197Å R work:0.215R free:0.258

NDB ID:

 2NCQ

PDB ID:

2NCQ 

Release:

2017-04-19

Title:

Structural insights of r(CGG) motif found in Fragile X Syndrome and Fragile-X associated tremor/ataxia syndrome (FXTAS) at 45 degree C

Classification:

RNA

Authors:

Mishra, S.K., Kumar, A.

Citation:

Structural insights reveal the dynamics of the repeating r(CGG) motif found in Fragile X Syndrome and Fragile-X associated tremor/ataxia syndrome (FXTAS)
To be Published pp. - 0

Experiment:

 SOLUTION NMR

NDB ID:

 2NCR

PDB ID:

2NCR 

Release:

2017-04-19

Title:

Structural insight for dynamics of r(CGG) motif RNA found in Fragile X syndrome/ Fragile X tremor ataxia at 25 degree C

Classification:

RNA

Authors:

Mishra, S.K., Kumar, A.

Citation:

Structural insights reveal the dynamics of the repeating r(CGG) motif found in Fragile X Syndrome and Fragile-X associated tremor/ataxia syndrome (FXTAS)
To be Published pp. - 0

Experiment:

 SOLUTION NMR

NDB ID:

 5UK4

PDB ID:

5UK4 

Release:

2017-04-19

Title:

VESICULAR STOMATITS VIRUS N PROTEIN IN COMPLEX WITH INHIBITORY NANOBODY 1307

Classification:

Viral Protein/RNA/Immune System

Authors:

Hanke, L., Schmidt, F.I., Knockenhauer, K.E., Morin, B., Whelan, S.P., Schwartz, T.U., Ploegh, H.L.

Citation:

Vesicular stomatitis virus N protein-specific single-domain antibody fragments inhibit replication.
EMBO Rep. 18 pp.1027 - 1037 2017

Experiment:

 X-RAY DIFFRACTION Resolution:3.204Å R work:0.236R free:0.287

NDB ID:

 5UKB

PDB ID:

5UKB 

Release:

2017-04-19

Title:

VSV N PROTEIN IN COMPLEX WITH INHIBITORY NANOBODY 1004

Classification:

Viral Protein/RNA/Immune System

Authors:

Hanke, L., Schmidt, F.I., Knockenhauer, K.E., Morin, B., Whelan, S.P., Schwartz, T.U., Ploegh, H.L.

Citation:

Vesicular stomatitis virus N protein-specific single-domain antibody fragments inhibit replication.
EMBO Rep. 18 pp.1027 - 1037 2017

Experiment:

 X-RAY DIFFRACTION Resolution:5.473Å R work:0.336R free:0.337

NDB ID:

 5V7C

PDB ID:

5V7C 

Release:

2017-04-19

Title:

Crystal structure of LARP1-unique domain DM15 bound 5'TOP RNA sequence

Classification:

RNA BINDING PROTEIN

Authors:

Lahr, R.M., Fonseca, B.D., Ciotti, G.E., Al-Ashtal, H.A., Jia, J.J., Niklaus, M.R., Blagden, S.P., Alain, T., Berman, A.J.

Citation:

La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs.
Elife 6 pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.59Å R work:0.206R free:0.235

NDB ID:

 5SZE

PDB ID:

5SZE 

Release:

2017-04-12

Title:

Crystal structure of Aquifex aeolicus Hfq-RNA complex at 1.5A

Classification:

RNA-binding protein/RNA

Authors:

Stanek, K.A., Patterson-West, J., Randolph, P.S., Mura, C.

Citation:

Crystal structure and RNA-binding properties of an Hfq homolog from the deep-branching Aquificae: conservation of the lateral RNA-binding mode.
Acta Crystallogr D Struct Biol 73 pp.294 - 315 2017

Experiment:

 X-RAY DIFFRACTION Resolution:1.5Å R work:0.144R free:0.172

NDB ID:

 5TSN

PDB ID:

5TSN 

Release:

2017-04-12

Title:

Crystal structures of Norwalk virus polymerase bound to an RNA primer-template duplex

Classification:

TRANSFERASE/RNA

Authors:

Shaik, M.M., Bhattacharjee, N., Feliks, M., Ng, K.K., Field, M.J.

Citation:

Norovirus RNA-dependent RNA polymerase: A computational study of metal-binding preferences.
Proteins pp. - 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.1Å R work:0.174R free:0.219

NDB ID:

 5UH5

PDB ID:

5UH5 

Release:

2017-04-12

Title:

Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3 nt of RNA

Classification:

TRANSCRIPTION/DNA/RNA

Authors:

Lin, W., Mandal, S., Degen, D., Liu, Y., Ebright, Y.W., Li, S., Feng, Y., Zhang, Y., Mandal, S., Jiang, Y., Liu, S., Gigliotti, M., Talaue, M., Connell, N., Das, K., Arnold, E., Ebright, R.H.

Citation:

Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell 66 pp.169 - 179.e8 2017

Experiment:

 X-RAY DIFFRACTION Resolution:3.746Å R work:0.193R free:0.248

NDB ID:

 5UH6

PDB ID:

5UH6 

Release:

2017-04-12

Title:

Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 2ntRNA in complex with Rifampin

Classification:

transcription/dna/rna/antibiotic

Authors:

Lin, W., Mandal, S., Degen, D., Liu, Y., Ebright, Y.W., Li, S., Feng, Y., Zhang, Y., Mandal, S., Jiang, Y., Liu, S., Gigliotti, M., Talaue, M., Connell, N., Das, K., Arnold, E., Ebright, R.H.

Citation:

Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell 66 pp.169 - 179.e8 2017

Experiment:

 X-RAY DIFFRACTION Resolution:3.837Å R work:0.211R free:0.263

NDB ID:

 5UH8

PDB ID:

5UH8 

Release:

2017-04-12

Title:

Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 4nt RNA

Classification:

TRANSCRIPTION/DNA/RNA

Authors:

Lin, W., Mandal, S., Degen, D., Liu, Y., Ebright, Y.W., Li, S., Feng, Y., Zhang, Y., Mandal, S., Jiang, Y., Liu, S., Gigliotti, M., Talaue, M., Connell, N., Das, K., Arnold, E., Ebright, R.H.

Citation:

Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell 66 pp.169 - 179.e8 2017

Experiment:

 X-RAY DIFFRACTION Resolution:4.176Å R work:0.2R free:0.256

NDB ID:

 5UH9

PDB ID:

5UH9 

Release:

2017-04-12

Title:

Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 2nt RNA

Classification:

TRANSCRIPTION/DNA/RNA

Authors:

Lin, W., Mandal, S., Degen, D., Liu, Y., Ebright, Y.W., Li, S., Feng, Y., Zhang, Y., Mandal, S., Jiang, Y., Liu, S., Gigliotti, M., Talaue, M., Connell, N., Das, K., Arnold, E., Ebright, R.H.

Citation:

Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell 66 pp.169 - 179.e8 2017

Experiment:

 X-RAY DIFFRACTION Resolution:4.402Å R work:0.281R free:0.331

NDB ID:

 5UHC

PDB ID:

5UHC 

Release:

2017-04-12

Title:

Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3nt RNA in complex with Rifampin

Classification:

TRANSCRIPTION/DNA/RNA

Authors:

Lin, W., Mandal, S., Degen, D., Liu, Y., Ebright, Y.W., Li, S., Feng, Y., Zhang, Y., Mandal, S., Jiang, Y., Liu, S., Gigliotti, M., Talaue, M., Connell, N., Das, K., Arnold, E., Ebright, R.H.

Citation:

Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell 66 pp.169 - 179.e8 2017

Experiment:

 X-RAY DIFFRACTION Resolution:3.796Å R work:0.204R free:0.266

NDB ID:

 5LM7

PDB ID:

5LM7 

Release:

2017-04-05

Title:

Crystal structure of the lambda N-Nus factor complex

Classification:

TRANSCRIPTION

Authors:

Said, N., Santos, K., Weber, G., Wahl, M.C.

Citation:

Crystal structure of the lambda N-Nus factor complex
To Be Published pp. - 0

Experiment:

 X-RAY DIFFRACTION Resolution:3.35Å R work:0.296R free:0.335

NDB ID:

 5UNE

PDB ID:

5UNE 

Release:

2017-03-29

Title:

Dimerized Structure Gives Further Insight Into the Function of the Novel RNA Gene: HAR1

Classification:

RNA

Authors:

Lares, M., Scott, W.G., Kimberly, T.

Citation:

Dimerized Structure Gives Further Insight Into the Function of the Novel RNA Gene: HAR1
To Be Published pp. - 0

Experiment:

 X-RAY DIFFRACTION Resolution:2.9001Å R work:0.2R free:0.249

NDB ID:

 5X2G

PDB ID:

5X2G 

Release:

2017-03-29

Title:

Crystal structure of Campylobacter jejuni Cas9 in complex with sgRNA and target DNA (AGAAACC PAM)

Classification:

HYDROLASE/RNA/DNA

Authors:

Yamada, M., Watanabe, Y., Gootenberg, J.S., Hirano, H., Ran, F.A., Nakane, T., Ishitani, R., Zhang, F., Nishimasu, H., Nureki, O.

Citation:

Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems
Mol. Cell 65 pp.1109 - 1121.e3 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.4Å R work:0.189R free:0.221

NDB ID:

 5X2H

PDB ID:

5X2H 

Release:

2017-03-29

Title:

Crystal structure of Campylobacter jejuni Cas9 in complex with sgRNA and target DNA (AGAAACA PAM)

Classification:

HYDROLASE/RNA/DNA

Authors:

Yamada, M., Watanabe, Y., Gootenberg, J.S., Hirano, H., Ran, F.A., Nakane, T., Ishitani, R., Zhang, F., Nishimasu, H., Nureki, O.

Citation:

Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems
Mol. Cell 65 pp.1109 - 1121.e3 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.3Å R work:0.2R free:0.231

NDB ID:

 5IP2

PDB ID:

5IP2 

Release:

2017-03-22

Title:

Tomato spotted wilt tospovirus nucleocapsid protein-ssRNA complex

Classification:

VIRAL PROTEIN/RNA

Authors:

Komoda, K., Narita, M., Yamashita, K., Tanaka, I., Yao, M.

Citation:

Crystal structure of TSWV nucleocapsid protein
to be published pp. - 0

Experiment:

 X-RAY DIFFRACTION Resolution:3.3Å R work:0.282R free:0.316

NDB ID:

 5UDZ

PDB ID:

5UDZ 

Release:

2017-03-22

Title:

Human LIN28A in complex with let-7f-1 microRNA pre-element

Classification:

RNA Binding Protein/RNA

Authors:

Wang, L., Nam, Y., Lee, A.K., Yu, C., Roth, K., Chen, C., Ransey, E.M., Sliz, P.

Citation:

LIN28 Zinc Knuckle Domain Is Required and Sufficient to Induce let-7 Oligouridylation.
Cell Rep 18 pp.2664 - 2675 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.0Å R work:0.164R free:0.2

NDB ID:

 5UJ2

PDB ID:

5UJ2 

Release:

2017-03-22

Title:

Crystal structure of HCV NS5B genotype 2A JFH-1 isolate with S15G E86Q E87Q C223H V321I mutations and Delta8 neta hairpoin loop deletion in complex with GS-639476 (diphsohate version of GS-9813), Mn2+ and symmetrical primer template 5'-AUAAAUUU

Classification:

immune system/RNA

Authors:

Kirschberg, T.A., Metobo, S., Clarke, M.O., Aktoudianakis, V., Babusis, D., Barauskas, O., Birkus, G., Butler, T., Byun, D., Chin, G., Doerffler, E., Edwards, T.E., Fenaux, M., Lee, R., Lew, W., Mish, M.R., Murakami, E., Park, Y., Squires, N.H., Tirunagari, N., Wang, T., Whitcomb, M., Xu, J., Yang, H., Ye, H., Zhang, L., Appleby, T.C., Feng, J.Y., Ray, A.S., Cho, A., Kim, C.U.

Citation:

Discovery of a 2'-fluoro-2'-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties.
Bioorg. Med. Chem. Lett. 27 pp.1840 - 1847 2017

Experiment:

 X-RAY DIFFRACTION Resolution:2.9Å R work:0.184R free:0.226

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