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NDB ID: 1FC8    PDB ID: 1FC8 


Title:

NMR SOLUTION STRUCTURE OF A CHIMERIC OLIGONUCLEOTIDE HAIRPIN R(GGAC)D(TTCG)2'F-A(GTCC)

Molecular Description:

NMR SOLUTION STRUCTURE OF A CHIMERIC OLIGONUCLEOTIDE HAIRPIN R(GGAC)D(TTCG)2'F-A(GTCC)

Structural Keywords:

DOUBLE HELIX, HAIRPIN, HYBRID DULEX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Trempe, J.F., Wilds, C.J., Denisov, A.Y., Pon, R.T., Damha, M.J., Gehring, K.
NMR solution structure of an oligonucleotide hairpin with a 2'F-ANA/RNA stem: implications for RNase H specificity toward DNA/RNA hybrid duplexes. 
J.Am.Chem.Soc., 123, pp. 4896 - 4903, 2001.

Experimental Information:

SOLUTION NMR

Space Group:

P 1

Cell Constants:

a = 1.0   b = 1.0   c = 1.0 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the program. The R value is for reflections in the resolution range to Ångstroms

Number of Models:

Number of Models: 5 Structures

Sample Details:

0.5 mM Oligonucleotide hairpin; 90% H2O, 10% D2O 90% H2O, 10% D2O