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NDB ID: PD0309    PDB ID: 1LE9 


Title:

CRYSTAL STRUCTURE OF A NF-KB HETERODIMER BOUND TO THE IG/HIV-KB SITI

Molecular Description:

NUCLEAR FACTOR NF-KAPPA-B P65 SUBUNIT/NUCLEAR FACTOR NF-KAPPA-B P50 SUBUNIT/DNA Complex

Deposited:

2002-04-09

Released:

2003-04-15

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASE

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Berkowitz, B., Huang, D.B., Chen-Park, F.E., Sigler, P.B., Ghosh, G.
The x-ray crystal structure of the NF-kappa B p50.p65 heterodimer bound to the interferon beta -kappa B site. 
J.Biol.Chem., 277, pp. 24694 - 24700, 2002.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 137.835   b = 138.002   c = 90.044 (Ångstroms)

α = 90.0   β = 97.28   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.0 for 28493 reflections in the resolution range 30.0 to 3.0 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)