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NDB ID: 1UTS    PDB ID: 1UTS 


Title:

DESIGNED HIV-1 TAR BINDING LIGAND

Molecular Description:

29-MER
N-[2-(3-AMINOPROPOXY)-5-(1H-INDOL-5-YL)BENZYL]-N-(2-PIPERAZIN-1-YLETHYL)AMINE

Structural Keywords:

SINGLE STRAND, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Murchie, A.I.H., Davis, B., Isel, C., Afshar, M., Drysdale, M.J., Bower, J., Potter, A.J., Starkey, I.D., Swarbrick, T.M., Mirza, S., Prescott, C.D., Vaglio, P., Aboul-Ela, F., Karn, J.
Structure-Based Drug Design Targeting an Inactive RNA Conformation: Exploiting the Flexibility of HIV-1 Tar RNA 
J.Mol.Biol., 236, pp. 625 - , 2004.

Experimental Information:

SOLUTION NMR

Space Group:

P 1

Cell Constants:

a = 1.0   b = 1.0   c = 1.0 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the program. The R value is for reflections in the resolution range to Ångstroms

Number of Models:

Number of Models: 16 Structures