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NDB ID: NA0261    PDB ID: 1GT0 


Title:

CRYSTAL STRUCTURE OF A POU/HMG/DNA TERNARY COMPLEX

Molecular Description:

OCTAMER-BINDING TRANSCRIPTION FACTOR 1
TRANSCRIPTION FACTOR SOX-2/DNA Complex

Deposited:

2002-01-09

Released:

2003-01-30

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASE PAIR

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Remenyi, A., Lins, K., Nissen, L.J., Reinbold, R., Scholer, H.R., Wilmanns, M.
Crystal Structure of a POU/Hmg/DNA Ternary Complex Suggests Differential Assembly of Oct4 and Sox2 on Two Enhancers 
Genes Dev., 17, pp. 2048 - , 2003.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 31 2 1

Cell Constants:

a = 72.8   b = 72.8   c = 172.4 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.232 for 16612 reflections in the resolution range 30.0 to 2.6 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)