As of 22-Jun-2022 number of released structures: 12128
Structural Features
Base Pair Hydrogen Bonding Classification
Nucleic Acid Backbone Torsions
Base Pair Morphology Parameters
Biological Assembly 1
RNA View
NDB ID: PD0477 PDB ID: 1R49 
Title:
HUMAN TOPOISOMERASE I (TOPO70) DOUBLE MUTANT K532R/Y723F
Molecular Description:
Deposited:
2003-10-03Released:
2003-12-16Structural Keywords:
B DOUBLE HELIX
Nucleic Acid Sequence:
Click to show/hide 2 nucleic acid sequences
Protein Sequence:
Click to show/hide 1 protein sequences
Primary Citation:
Interthal, H., Quigley, P.M., Hol, W.G., Champoux, J.J.
The role of lysine 532 in the catalytic mechanism of human topoisomerase I.
J.Biol.Chem., 279, pp. 2984 - 2992, 2004.
Experimental Information:
X-RAY DIFFRACTION
Space Group:
P 1 21 1
Cell Constants:
a = 56.944 b = 118.638 c = 71.651 (Ångstroms)
α = 90.0 β = 98.33 γ = 90.0 (degrees)
Refinement:
The structure was refined using the REFMAC program. The R value is 0.28009 for 14675 reflections in the resolution range 47.67 to 3.13 Ångstroms with Fobs > 0.0 sigma(Fobs) and with I > 0.0 sigma(I)
Download Data:
Asymmetric Unit coordinates (pdb format, Unix compressed(.gz))
Asymmetric Unit coordinates (cif format, Unix compressed(.gz))
Biological Assembly coordinates (pdb format) 1
Structure Factors (cif format)
Coordinates (pdb format, Unix compressed(.gz))
Coordinates (cif format, Unix compressed(.gz))
NMR Restraints (cif format, Unix compressed(.gz))
XML | Complete with coordinates (xml format, GNU compressed(.gz))