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NDB ID: 2GKU    PDB ID: 2GKU 


Title:

MONOMERIC HUMAN TELOMERE DNA TETRAPLEX WITH 3+1 STRAND FOLD TOPOLOGY, TWO EDGEWISE LOOPS AND DOUBLE-CHAIN REVERSAL LOOP, NMR, 12 STRUCTURES

Molecular Description:

5'-D(*TP*TP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*A)-3'

Deposited:

2006-04-03

Released:

2006-08-15

Structural Keywords:

QUADRUPLE HELIX, BASE INTERCALATED, TETRAPLEX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Luu, K.N., Phan, A.T., Kuryavyi, V.V., Lacroix, L., Patel, D.J.
Structure of the human telomere in k(+) solution: an intramolecular (3 + 1) g-quadruplex scaffold. 
J.Am.Chem.Soc., 128, pp. 9963 - 9970, 2006.

Experimental Information:

SOLUTION NMR

Space Group:

P 1

Number of Models:

Number of Models: 12 Structures

Sample Details:

70 MM KCL 20 MM POTASSIUM PHOSPHATE 90% H2O 10% D2O 90% H2O/10% D2O