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NDB ID: 2GVO    PDB ID: 2GVO 


Title:

SOLUTION STRUCTURE OF A PURINE RICH HEXALOOP HAIRPIN BELONGING TO PGY/MDR1 MRNA AND TARGETED BY ANTISENSE OLIGONUCLEOTIDES

Molecular Description:

5'-R(*GP*AP*GP*GP*UP*CP*GP*GP*GP*AP*UP*GP*GP*AP*UP*CP*UP*C)-3'

Structural Keywords:

SINGLE STRAND, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Joli, F., Bouchemal, N., Laigle, A., Hartmann, B., Hantz, E.
Solution structure of a purine rich hexaloop hairpin belonging to PGY/MDR1 mRNA and targeted by antisense oligonucleotides. 
Nucleic Acids Res., 34, pp. 5740 - 5751, 2006.

Experimental Information:

SOLUTION NMR

Space Group:

P 1

Cell Constants:

a = 1.0   b = 1.0   c = 1.0 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the program. The R value is for reflections in the resolution range to Ångstroms

Number of Models:

Number of Models: 21 Structures

Sample Details:

1mM 18mer mRNA uniformly 13C/15N labeled, 10 mM Sodium phosphate buffer, 90% H2O, 10% D2O 90% H2O, 10% D2O