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NDB ID: 2JZW    PDB ID: 2JZW 


Title:

HOW THE HIV-1 NUCLEOCAPSID PROTEIN BINDS AND DESTABILISES THE (-)PRIMER BINDING SITE DURING REVERSE TRANSCRIPTION

Molecular Description:

HIV-1 nucleocapsid protein NCp7(12-55)/DNA Complex

Deposited:

2008-01-21

Released:

2009-01-13

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Bourbigot, S., Ramalanjaona, N., Boudier, C., Salgado, G.F., Roques, B.P., Mely, Y., Bouaziz, S., Morellet, N.
How the HIV-1 nucleocapsid protein binds and destabilises the (-)primer binding site during reverse transcription. 
J.Mol.Biol., 383, pp. 1112 - 1128, 2008.

Experimental Information:

SOLUTION NMR

Number of Models:

Number of Models: 19 Structures

Sample Details:

1 mM NCp7(12-55), 1 mM P(-)PBS, 3 mM ZnCl2, 30 mM sodium chloride, 0.2 mM MgCl2, 90% H2O/10% D2O 90% H2O/10% D2O