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NDB ID: 2KGP    PDB ID: 2KGP 


Title:

STRUCTURAL BASIS FOR STABILIZATION OF THE TAU PRE-MRNA SPLICING REGULATORY ELEMENT BY NOVANTRONE (MITOXANTRONE)

Molecular Description:

25-MER

Deposited:

2009-03-13

Released:

2009-06-02

Structural Keywords:

B DOUBLE HELIX, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Zheng, S., Chen, Y., Donahue, C.P., Wolfe, M.S., Varani, G.
Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by novantrone (mitoxantrone). 
Chem.Biol., 16, pp. 557 - 566, 2009.

Experimental Information:

SOLUTION NMR

Number of Models:

Number of Models: 10 Structures

Sample Details:

0.8~1.8 mM tau pre-mRNA splicing regulatory element-1, 95% H2O/5% D2O 95% H2O/5% D2O