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NDB ID: 2KMJ    PDB ID: 2KMJ 


Title:

HIGH RESOLUTION NMR SOLUTION STRUCTURE OF A COMPLEX OF HIV-2 TAR RNA AND A SYNTHETIC TRIPEPTIDE IN A 1:2 STOICHIOMETRY

Molecular Description:

PROTEIN/RNA Complex

Deposited:

2009-07-30

Released:

2009-08-18

Structural Keywords:

A DOUBLE HELIX, BULGES, MISMATCHED BASE PAIRS

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Ferner, J., Suhartono, M., Breitung, S., Jonker, H.R.A., Hennig, M., Wohnert, J., Gobel, M., Schwalbe, H.
Structures of HIV TAR RNA-ligand complexes reveal higher binding stoichiometries. 
Chembiochem, 10, pp. 1490 - 1494, 2009.

Experimental Information:

SOLUTION NMR

Number of Models:

Number of Models: 10 Structures

Sample Details:

0.65 mM [U-100% 13C; U-100% 15N] UUCG-TAR-1, 5.2 mM Pyrimidinylpeptide-2, 50 mM potassium chloride-3, 25 mM potassium phosphate-4, 90% H2O/10% D2O 90% H2O/10% D2O