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NDB ID: 2KOW    PDB ID: 2KOW 


Title:

STRUCTURE OF A TWO-G-TETRAD BASKET-TYPE INTRAMOLECULAR G-QUADRUPLEX FORMED BY GIARDIA TELOMERIC REPEAT D(TAGGG)4 IN K+ SOLUTION (WITH G18-TO-INO SUBSTITUTION)

Molecular Description:

5'-D(*TP*AP*GP*GP*GP*TP*AP*GP*GP*GP*TP*AP*GP*GP*GP*TP*AP*IP*GP*G)-3'

Deposited:

2009-10-02

Released:

2009-11-17

Structural Keywords:

QUADRUPLE HELIX, INTERNAL LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Hu, L., Lim, K.W., Bouaziz, S., Phan, A.T.
Giardia Telomeric Sequence d(TAGGG)(4) Forms Two Intramolecular G-Quadruplexes in K(+) Solution: Effect of Loop Length and Sequence on the Folding Topology. 
J.Am.Chem.Soc., 131, pp. 16824 - 16831, 2009.

Experimental Information:

SOLUTION NMR

Number of Models:

Number of Models: 10 Structures

Sample Details:

0.5-2.0mM DNA (5'-D(*TP*AP*GP*GP*GP*TP*AP*GP*GP*GP*TP*AP*GP*GP*GP*TP*AP*IP*GP*G)-3')-1, 90% H2O/10% D2O 90% H2O/10% D2O