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NDB ID: 2L1V    PDB ID: 2L1V 


Title:

SOLUTION STRUCTURE OF A PREQ1 RIBOSWITCH (CLASS I) APTAMER BOUND TO PREQ1

Molecular Description:

RNA 36-MER
7-DEAZA-7-AMINOMETHYL-GUANINE

Structural Keywords:

SINGLE STRAND, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Kang, M., Peterson, R.D., Feigon, J.
Structural Insights into Riboswitch Control of the Biosynthesis of Queuosine, a Modified Nucleotide Found in the Anticodon of tRNA 
Mol.Cell, 33, pp. 784 - 790, 2009.

Experimental Information:

SOLUTION NMR

Cell Constants:

a =   b =   c = (Ångstroms)

α =   β =   γ = (degrees)

Refinement:

The structure was refined using the program. The R value is for reflections in the resolution range to Ångstroms

Number of Models:

Number of Models: 20 Structures

Sample Details:

1 mM preQ1-RNA 36mer, 1 mM [U-13C; U-15N]-Cyt preQ1-RNA 36mer, 1 mM [U-13C; U-15N]-Ade preQ1-RNA 36mer, 1 mM [U-13C; U-15N]-Gua preQ1-RNA 36mer, 1 mM [U-13C; U-15N]-Ura preQ1-RNA 36mer, 1 mM U-H5,3',4',5',5''-2H preQ1-RNA 36mer, 100% D2O 100% D2O