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NDB ID: 2L8W    PDB ID: 2L8W 


Title:

R(CCGCUGCGG)2 UU INTERNAL LOOP FOUND IN MYOTONIC DYSTROPHY TYPE 1 - UU PAIR WITH TWO HYDROGEN BOND PAIRS

Molecular Description:

5'-R(*CP*CP*GP*CP*UP*GP*CP*GP*G)-3'

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Parkesh, R., Fountain, M., Disney, M.D.
NMR Spectroscopy and Molecular Dynamics Simulation of r(CCGCUGCGG)(2) Reveal a Dynamic UU Internal Loop Found in Myotonic Dystrophy Type 1. 
Biochemistry, 50, pp. 599 - 601, 2011.

Experimental Information:

SOLUTION NMR

Cell Constants:

a =   b =   c = (Ångstroms)

α =   β =   γ = (degrees)

Refinement:

The structure was refined using the program. The R value is for reflections in the resolution range to Ångstroms

Number of Models:

Number of Models: 1 Structures

Sample Details:

1.5 mM RNA (5'-R(*CP*CP*GP*CP*UP*GP*CP*GP*G)-3'), 100% D2O 100% D2O