NDB ID: 2LA5    PDB ID: 2LA5 

Title:

RNA DUPLEX-QUADRUPLEX JUNCTION COMPLEX WITH FMRP RGG PEPTIDE

Molecular Description:

Fragile X mental retardation 1 protein/RNA Complex

Structural Keywords:

SINGLE STRAND, TETRAPLEX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Phan, A.T., Kuryavyi, V., Darnell, J.C., Serganov, A., Majumdar, A., Ilin, S., Raslin, T., Polonskaia, A., Chen, C., Clain, D., Darnell, R.B., Patel, D.J.
Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction. 
Nat.Struct.Mol.Biol., 18, pp. 796 - 804, 2011.

Experimental Information:

SOLUTION NMR

Cell Constants:

a =   b =   c = (Ångstroms)

α =   β =   γ = (degrees)

Refinement:

The structure was refined using the program. The R value is for reflections in the resolution range to Ångstroms

Number of Models:

Number of Models: 10 Structures

Sample Details:

1 mM RNA (36-MER), 1 mM Peptide, 90% H2O/10% D2O and 100%D2O 90% H2O/10% D2O and 100%D2O

Download Data:

Asymmetric Unit coordinates (pdb format, Unix compressed(.gz))

Asymmetric Unit coordinates (cif format, Unix compressed(.gz))

Biological Assembly coordinates (pdb format) 

Structure Factors (cif format)

Coordinates (pdb format, Unix compressed(.gz))

Coordinates (cif format, Unix compressed(.gz))

NMR Restraints (cif format, Unix compressed(.gz))

XML | Complete with coordinates (xml format, GNU compressed(.gz))

XML | Coordinates only (xml format, GNU compressed(.gz))

XML | Header only (xml format, GNU compressed(.gz))