NDB ID: 2LA5    PDB ID: 2LA5 

Title:

RNA DUPLEX-QUADRUPLEX JUNCTION COMPLEX WITH FMRP RGG PEPTIDE

Molecular Description:

Fragile X mental retardation 1 protein/RNA Complex

Structural Keywords:

DOUBLE HELIX, TETRAPLEX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Phan, A.T., Kuryavyi, V., Darnell, J.C., Serganov, A., Majumdar, A., Ilin, S., Raslin, T., Polonskaia, A., Chen, C., Clain, D., Darnell, R.B., Patel, D.J.
Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction. 
Nat.Struct.Mol.Biol., 18, pp. 796 - 804, 2011.

Experimental Information:

SOLUTION NMR

Cell Constants:

a =   b =   c = (Ångstroms)

α =   β =   γ = (degrees)

Refinement:

The structure was refined using the program. The R value is for reflections in the resolution range to Ångstroms

Number of Models:

Number of Models: 10 Structures

Sample Details:

1 mM RNA (36-MER), 1 mM Peptide, 90% H2O/10% D2O and 100%D2O 90% H2O/10% D2O and 100%D2O

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