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NDB ID: 2LB4    PDB ID: 2LB4 


Title:

DNA / RNA HYBRID CONTAINING A CENTRAL STEREO SPECIFIC SP BORANO PHOSPHATE LINKAGE

Molecular Description:

5'-D(*AP*TP*GP*GP*TP*(BGR)P*CP*TP*C)-3'

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Johnson, C.N., Spring, A.M., Sergueev, D., Shaw, B.R., Germann, M.W.
Structural Basis of the RNase H1 Activity on Stereo Regular Borano Phosphonate DNA/RNA Hybrids. 
Biochemistry, 50, pp. 3903 - 3912, 2011.

Experimental Information:

SOLUTION NMR

Space Group:

P 1

Cell Constants:

a = 1.0   b = 1.0   c = 1.0 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the program. The R value is for reflections in the resolution range to Ångstroms

Number of Models:

Number of Models: 1 Structures

Sample Details:

1.0 mM DNA (5'-D(*AP*TP*GP*GP*TP*BGR*CP*TP*C)-3'), 1.0 mM RNA (5'-R(*GP*AP*GP*CP*AP*CP*CP*AP*U)-3'), 50 mM sodium chloride, 10 mM sodium phosphate, 0.5 mM EDTA, 0.3 uM DSS, 10 % D2O, 90 % H2O, 90% H2O/10% D2O 90% H2O/10% D2O