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NDB ID: 2LEB    PDB ID: 2LEB 


Title:

SOLUTION STRUCTURE OF HUMAN SRSF2 (SC35) RRM IN COMPLEX WITH 5'-UCCAGU-3'

Molecular Description:

Serine/arginine-rich splicing factor 2/RNA complex

Deposited:

2011-06-15

Released:

2011-11-23

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Daubner, G.M., Clery, A., Jayne, S., Stevenin, J., Allain, F.H.
A syn-anti conformational difference allows SRSF2 to recognize guanines and cytosines equally well. 
Embo J., 31, pp. 162 - 174, 2012.

Experimental Information:

SOLUTION NMR

Number of Models:

Number of Models: 20 Structures

Sample Details:

0.75 mM [U-15N] SRSF2 RRM + UCCAGU1, 0.75 mM [U-13C; U-15N] SRSF2 RRM + UCCAGU2, 90% H2O/10% D2O 90% H2O/10% D2O