A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 25-May-2016 number of released structures: 8217
Search for released structures

NDB ID: 2LWK    PDB ID: 2LWK 


Title:

SOLUTION STRUCTURE OF SMALL MOLECULE-INFLUENZA RNA COMPLEX

Molecular Description:

32-MER

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Lee, M.K., Bottini, A., Kim, M., Bardaro, M.F., Zhang, Z., Pellecchia, M., Choi, B.S., Varani, G.
A novel small-molecule binds to the influenza A virus RNA promoter and inhibits viral replication. 
Chem.Commun.(Camb.), 50, pp. 368 - 370, 2014.

Experimental Information:

SOLUTION NMR

Cell Constants:

a =   b =   c = (Ångstroms)

α =   β =   γ = (degrees)

Refinement:

The structure was refined using the program. The R value is for reflections in the resolution range to Ångstroms

Number of Models:

Number of Models: 16 Structures

Sample Details:

1 mM influenza A virus RNA promoter, 90% H2O, 10% D2O 90% H2O, 10% D2O