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NDB ID: 2RMQ    PDB ID: 2RMQ 


Title:

SOLUTION STRUCTURE OF FULLY MODIFIED 4'-THIODNA WITH THE SEQUENCE OF D(CGCGAATTCGCG)

Molecular Description:

5'-D(*(C4S)P*(S4G)P*(C4S)P*(S4G)P*(S4A)P*(S4A)P*(T49)P*(T49)P*(C4S)P*(S4G)P*(C4S)P*(S4G))-3'

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Matsugami, A., Ohyama, T., Inada, M., Inoue, N., Minakawa, N., Matsuda, A., Katahira, M.
Unexpected A-form formation of 4'-thioDNA in solution, revealed by NMR, and the implications as to the mechanism of nuclease resistance 
Nucleic Acids Res., 36, pp. 1805 - 1812, 2008.

Experimental Information:

SOLUTION NMR

Cell Constants:

a =   b =   c = (Ångstroms)

α =   β =   γ = (degrees)

Refinement:

The structure was refined using the program. The R value is for reflections in the resolution range to Ångstroms

Number of Models:

Number of Models: 1 Structures

Sample Details:

0.42mM 4'-thio DNA; 10mM sodium phosphate; 10mM sodium chloride; 0.01mM DSS; 95% H2O, 5% D2O 95% H2O, 5% D2O