A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 28-Sep-2016 number of released structures: 8524
Search for released structures

NDB ID: 2RN1    PDB ID: 2RN1 


Title:

LIQUID CRYSTAL SOLUTION STRUCTURE OF THE KISSING COMPLEX FORMED BY THE APICAL LOOP OF THE HIV TAR RNA AND A HIGH AFFINITY RNA APTAMER OPTIMIZED BY SELEX

Molecular Description:

5'-R(P*GP*AP*GP*CP*CP*CP*UP*GP*GP*GP*AP*GP*GP*CP*UP*C)-3'
5'-R(P*GP*CP*UP*GP*GP*UP*CP*CP*CP*AP*GP*AP*CP*AP*GP*C)-3'

Structural Keywords:

SINGLE STRAND, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Van Melckebeke, H., Devany, M., Di Primo, C., Beaurain, F., Bryce, D.L., Boisbouvier, J.
Liquid-crystal NMR structure of HIV TAR RNA bound to its SELEX RNA aptamer reveals the origins of the high stability of the complex 
Proc.Natl.Acad.Sci.Usa, 105, pp. 9210 - 9215, 2008.

Experimental Information:

SOLUTION NMR

Cell Constants:

a =   b =   c = (Ångstroms)

α =   β =   γ = (degrees)

Refinement:

The structure was refined using the program. The R value is for reflections in the resolution range to Ångstroms

Number of Models:

Number of Models: 17 Structures

Sample Details:

1.3mM TAR, 1.3mM TAR*GA, 10mM sodium phosphate, 50mM sodium chloride, 0.01mM EDTA, 0.4g/L sodium azide, 100% D2O 100% D2O