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NDB ID: 2RRC    PDB ID: 2RRC 


Title:

SOLUTION STRUCTURE OF RNA APTAMER AGAINST AML1 RUNT DOMAIN

Molecular Description:

5'-R(P*GP*GP*AP*CP*CP*CP*(AP7)P*CP*CP*AP*CP*GP*GP*CP*GP*AP*GP*GP*UP*CP*CP*A)-3'

Structural Keywords:

SINGLE STRAND, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Nomura, Y., Fukunaga, J., Tanaka, Y., Fujiwara, K., Chiba, M., Iibuchi, H., Tanaka, T., Nakamura, Y., Kawai, G., Sakamoto, T., Kozu, T.
A novel high affinity RNA motif that mimics DNA in AML1 Runt domain binding
To be Published, , pp. - , 0.

Experimental Information:

SOLUTION NMR

Space Group:

P 1

Cell Constants:

a = 1.0   b = 1.0   c = 1.0 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the program. The R value is for reflections in the resolution range to Ångstroms

Number of Models:

Number of Models: 11 Structures

Sample Details:

0.6 mM AML22-1, 0.5 mM [U-100% 13C; U-100% 15N] AML22-2, 100% D2O 100% D2O