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NDB ID: PD0702    PDB ID: 2AJQ 


Title:

STRUCTURE OF REPLICATIVE DNA POLYMERASE PROVIDES INSIGTS INTO THE MECHANISMS FOR PROCESSIVITY, FRAMESHIFTING AND EDITING

Molecular Description:

T7 DNA polymerase (E.C.2.7.7.7)/thioredoxin 1/DNA complex

Deposited:

2005-08-02

Released:

2006-09-26

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Brieba, L., Ellenberger, T.
Structure of replicative DNA polymerase provides insigts into the mechanisms for processivity, frameshifting and editing
To be Published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 168.312   b = 169.235   c = 179.788 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.2331 for 78685 reflections in the resolution range 45.97 to 2.6 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)