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NDB ID: PD0826    PDB ID: 2HHT 


Title:

C:O6-METHYL-GUANINE PAIR IN THE POLYMERASE-2 BASEPAIR POSITION

Molecular Description:

DNA polymerase I (E.C.2.7.7.7)/DNA Complex

Deposited:

2006-06-28

Released:

2006-12-12

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Warren, J.J., Forsberg, L.J., Beese, L.S.
The structural basis for the mutagenicity of O6-methyl-guanine lesions. 
Proc.Natl.Acad.Sci.Usa, 103, pp. 19701 - 19706, 2006.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 87.864   b = 93.431   c = 107.071 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.0 for 50609 reflections in the resolution range 50.0 to 2.05 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)