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NDB ID: PD0911    PDB ID: 2J6T 


Title:

TERNARY COMPLEX OF SULFOLOBUS SOLFATARICUS DPO4 DNA POLYMERASE, O6- METHYLGUANINE MODIFIED DNA, AND DATP.

Molecular Description:

DNA POLYMERASE IV (E.C.2.7.7.7)

Deposited:

2006-10-04

Released:

2006-11-22

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Eoff, R.L., Irimia, A., Egli, M., Guengerich, F.P.
Sulfolobus Solfataricus DNA Polymerase Dpo4 is Partially Inhibited by ""Wobble"" Pairing between O6- Methylguanine and Cytosine, But Accurate Bypass is Preferred. 
J.Biol.Chem., 282, pp. 1456 - , 2007.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 95.012   b = 102.949   c = 53.013 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.237 for 16550 reflections in the resolution range 22.5 to 2.6 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)