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NDB ID: PD0983    PDB ID: 2P66 


Title:

HUMAN DNA POLYMERASE BETA COMPLEXED WITH TETRAHYDROFURAN (ABASIC SITE) CONTAINING DNA

Molecular Description:

DNA polymerase beta/DNA Complex

Deposited:

2007-03-16

Released:

2007-04-10

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Prasad, R., Batra, V.K., Yang, X.-P., Krahn, J.M., Pedersen, L.C., Beard, W.A., Wilson, S.H.
Structural insight into the DNA Polymerase beta deoxyribose phosphate lyase mechanism 
DNA REPAIR, 4, pp. 1347 - 1357, 2005.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 55.7   b = 81.1   c = 54.9 (Ångstroms)

α = 90.0   β = 108.6   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.217 for 14019 reflections in the resolution range 24.06 to 2.5 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)