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NDB ID: PD0992    PDB ID: 2PFQ 


Title:

MANGANESE PROMOTES CATALYSIS IN A DNA POLYMERASE LAMBDA-DNA CRYSTAL

Molecular Description:

DNA polymerase lambda (E.C. 2.7.7.7
E.C.4.2.99.-)/DNA Complex

Deposited:

2007-04-05

Released:

2007-05-15

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Garcia-Diaz, M., Bebenek, K., Krahn, J.M., Pedersen, L.C., Kunkel, T.A.
Role of the catalytic metal during polymerization by DNA polymerase lambda. 
DNA Repair, 6, pp. 1333 - 1340, 2007.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 56.091   b = 63.485   c = 139.775 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.0 for 25703 reflections in the resolution range 50.0 to 2.1 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)