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NDB ID: NA0311    PDB ID: 2V9W 


Title:

COMPLEX STRUCTURE OF SULFOLOBUS SOLFATARICUS DPO4 AND DNA DUPLEX CONTAINING A HYDROPHOBIC THYMINE ISOSTERE 2,4-DIFLUOROTOLUENE NUCLEOTIDE IN THE TEMPLATE STRAND

Molecular Description:

DNA POLYMERASE IV (E.C.2.7.7.7)

Deposited:

2007-08-27

Released:

2007-10-30

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Irimia, A., Eoff, R.L., Pallan, P.S., Guengerich, F.P., Egli, M.
Structure and Activity of Y-Class DNA Polymerase Dpo4 from Sulfolobus Solfataricus with Templates Containing the Hydrophobic Thymine Analog 2,4-Difluorotoluene. 
J.Biol.Chem., 282, pp. 36421 - , 2007.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 52.704   b = 186.744   c = 52.73 (Ångstroms)

α = 90.0   β = 110.06   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.218 for 16763 reflections in the resolution range 49.51 to 3.0 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)