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NDB ID: NA0725    PDB ID: 3AN2 


Title:

THE STRUCTURE OF THE CENTROMERIC NUCLEOSOME CONTAINING CENP-A

Molecular Description:

Histone H3-like centromeric protein A
Histone H4
Histone H2A type 1-B/E
Histone H2B type 1-J

Deposited:

2010-08-27

Released:

2011-07-20

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 4 protein sequences

Primary Citation:

Tachiwana, H., Kagawa, W., Shiga, T., Osakabe, A., Miya, Y., Saito, K., Hayashi-Takanaka, Y., Oda, T., Sato, M., Park, S.-Y., Kimura, H., Kurumizaka, H.
Crystal structure of the human centromeric nucleosome containing CENP-A 
Nature, 476, pp. 232 - 235, 2011.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 65.84   b = 83.29   c = 176.83 (Ångstroms)

α = 90.0   β = 100.7   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.271 for 21021 reflections in the resolution range 50.0 to 3.6 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)