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NDB ID: PD1068    PDB ID: 3BRF 


Title:

CSL (LAG-1) BOUND TO DNA WITH LIN-12 RAM PEPTIDE, C2221

Molecular Description:

Lin-12 and glp-1 phenotype protein 1
isoform a
Protein lin-12/DNA Complex

Deposited:

2007-12-21

Released:

2008-04-01

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Friedmann, D.R., Wilson, J.J., Kovall, R.A.
RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex. 
J.Biol.Chem., 283, pp. 14781 - 14791, 2008.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 62.944   b = 95.972   c = 223.63 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.232 for 24719 reflections in the resolution range 28.28 to 2.47 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)