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NDB ID: NA1144    PDB ID: 3AZI 


Title:

CRYSTAL STRUCTURE OF HUMAN NUCLEOSOME CORE PARTICLE CONTAINING H4K31Q MUTATION

Molecular Description:

Histone H3.1
Histone H4
Histone H2A type 1-B/E
Histone H2B type 1-J/DNA

Deposited:

2011-05-25

Released:

2011-09-21

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 4 protein sequences

Primary Citation:

Iwasaki, W., Tachiwana, H., Kawaguchi, K., Shibata, T., Kagawa, W., Kurumizaka, H.
Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains 
Biochemistry, 50, pp. 7822 - 7832, 2011.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 106.361   b = 109.451   c = 176.006 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.0 for 56732 reflections in the resolution range 38.14 to 2.7 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)