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NDB ID: PD1141    PDB ID: 3C5G 


Title:

STRUCTURE OF A TERNARY COMPLEX OF THE R517K POL LAMBDA MUTANT

Molecular Description:

DNA polymerase lambda/DNA Complex

Deposited:

2008-01-31

Released:

2008-07-29

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Bebenek, K., Garcia-Diaz, M., Foley, M.C., Pedersen, L.C., Schlick, T., Kunkel, T.A.
Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase lambda. 
Embo Rep., 9, pp. 459 - 464, 2008.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 94.335   b = 150.819   c = 85.822 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.0 for 55423 reflections in the resolution range 50.0 to 2.2 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)