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NDB ID: PD1104    PDB ID: 3COA 


Title:

CRYSTAL STRUCTURE OF FOXO1 DBD BOUND TO IRE DNA

Molecular Description:

Forkhead box protein O1/DNA Complex

Deposited:

2008-03-27

Released:

2008-09-16

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Brent, M.M., Anand, R., Marmorstein, R.
Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification. 
Structure, 16, pp. 1407 - 1416, 2008.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 76.062   b = 102.432   c = 65.446 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.0 for 47874 reflections in the resolution range 30.0 to 2.2 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)