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NDB ID: NA1062    PDB ID: 3REH 


Title:

2.5 ANGSTROM CRYSTAL STRUCTURE OF THE NUCLEOSOME CORE PARTICLE ASSEMBLED WITH A 145 BP ALPHA-SATELLITE DNA (NCP145)

Molecular Description:

Histone H3.2
Histone H4
Histone H2A type 1
Histone H2B 1.1/DNA complex

Deposited:

2011-04-04

Released:

2012-03-14

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 4 protein sequences

Primary Citation:

Wu, B., Davey, G.E., Nazarov, A.A., Dyson, P.J., Davey, C.A.
Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation. 
Nucleic Acids Res., 39, pp. 8200 - 8212, 2011.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 105.606   b = 110.066   c = 181.719 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.23701 for 72054 reflections in the resolution range 91.0 to 2.5 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)