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NDB ID: NA1406    PDB ID: 3UQ0 


Title:

CRYSTAL STRUCTURE OF THE POST-CATALYTIC PRODUCT COMPLEX OF POLYMERASE LAMBDA WITH AN RAMP AT THE PRIMER TERMINUS.

Molecular Description:

DNA polymerase lambda (E.C.2.7.7.7
4.2.99.-)/DNA complex

Deposited:

2011-11-18

Released:

2012-05-23

Structural Keywords:

B DOUBLE HELIX, NICKED

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Gosavi, R.A., Moon, A.F., Kunkel, T.A., Pedersen, L.C., Bebenek, K.
The catalytic cycle for ribonucleotide incorporation by human DNA Pol lambda 
Nucleic Acids Res., 40, pp. 7518 - 7527, 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 55.843   b = 64.241   c = 139.29 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1968 for 26459 reflections in the resolution range 25.916 to 2.14 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)