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NDB ID: NA1385    PDB ID: 3VK7 


Title:

CRYSTAL STRUCTURE OF DNA-GLYCOSYLASE BOUND TO DNA CONTAINING 5-HYDROXYURACIL

Molecular Description:

Probable formamidopyrimidine-DNA glycosylase (E.C.3.2.2.23
4.2.99.18)/DNA complex

Deposited:

2011-11-10

Released:

2011-12-14

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Imamura, K., Averill, A., Wallace, S.S., Doublie, S.
Structural characterization of viral ortholog of human DNA glycosylase NEIL1 bound to thymine glycol or 5-hydroxyuracil-containing DNA 
J.Biol.Chem., 287, pp. 4288 - 4298, 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 39.703   b = 121.594   c = 81.121 (Ångstroms)

α = 90.0   β = 95.49   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2179 for 40659 reflections in the resolution range 28.296 to 2.1 Ångstroms with Fobs >  1.0 sigma(Fobs) and with I >  0.0 sigma(I)